Clinical trials: Screening Score
Prostate Cancer, Polygenic Risk Score
Polygenic Risk Stratification Combined With mpMRI to Identify Clinically Relevant Prostate Cancer
The goal of this clinical trial is to evaluate a screening method to detect clinically relevant prostate cancer. This clinical trial is using genetic data to determine a man's risk of cancer, together with multiparametric…
- Trial name
- PRS (NCT06398639)
- Testing
- Polygenic Risk Score (PRS)
- Where
- 5 sites in United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Adam S. Kibel, MD
Colorectal Cancer
Scaling CRC Screening Through Outreach, Referral, and Engagement (SCORE)
This study will test the effectiveness of mailing fecal immunochemical tests (FITs) in increasing colorectal cancer (CRC) screening rates in U.S. adults ages 45-75.
- Trial name
- SCORE (NCT04406714)
- Testing
- Trial Mailed FIT Intervention - Age Group 50-75, Sub-Study Mailed FIT Intervention Enhanced Envelope - Age Group 45-49, Sub-Study Mailed FIT Active Comparator Plain Envelope - Age Group 45-49
- Where
- 2 sites in United States
- Volunteers
- 4,318 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Atherosclerosis of Artery
Screening for Atherotic Plaques by Ultrasound for Assessing Cardiovascular Risk
Cardiovascular disease is a common diagnosed and treated condition in private practices of primary health care. There is growing evidence that atherosclerotic plaques as predictors for stroke and heart attack are more prevalent…
- Trial name
- NCT03499496
- Testing
- ultrasound guided detection of atherosclerotic plaques
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cabinet de Medecine Interne Générale Demetrio Pitarch
Diabetes Mellitus, Type 2, Prediabetic State
PREDICT-DM: Community Pharmacy-Based Point-of-Care Testing for Undiagnosed T2DM
The goal of this observational study is to learn whether community pharmacy-based risk assessment and point-of-care HbA1c testing can help detect undiagnosed type 2 diabetes and prediabetes among adults in Irbid Governorate…
- Conditions
- Diabetes Mellitus, Type 2, Prediabetic State, Prediabetes / Type 2 Diabetes, T2DM
- Trial name
- PREDICT-DM (NCT07795918)
- Where
- Jordan
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Type 2 Diabetes
Evaluation of SCOUT DS Device in the Diagnosis of Diabetes
The primary objective is to identify compare SCOUT DS to random capillary glucose for identification of at-risk subjects with dysglycemia defined by hemoglobin A1c ≥ 6.0%.
- Trial name
- NCT01634997
- Where
- United Kingdom
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- VeraLight, Inc.
Sleep Apnea, Obstructive
Comparison of Different Screening Score for Hypoxemic OSA (Obstructive Sleep Apnea) With the Results of a Polysomnography (PSG)
Comparison of different screening score for hypoxemic OSA (Obstructive Sleep Apnea) with the results of a polysomnography (PSG). The different screening score studied are: STOP-BANG, DES-OSA, P-SAP and OSA50.
- Trial name
- NCT02050685
- Testing
- All patients incoming in the sleep study centre for a PSG
- Where
- Belgium
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Eric DEFLANDRE, MD, FCCP
Colorectal Cancer Screening, Colon Polyps and Adenomas
Artificial Intelligence (AI) Technology May Help Patients to Understand Bowel Preparation Better Before They go for Colonoscopy.This Study Attempts to Leverage AI Chatbot in Counselling Patients to Improve Bowel Cleanliness, Reduce Anxiety as Well as Increase Procedural Satisfaction
Traditional pre-colonoscopy counselling requires significant time from healthcare workers to explain procedures, limiting efficiency and patient turnover.
- Conditions
- Colorectal Cancer Screening, Colon Polyps and Adenomas, Bowel Preparation Quality, Artificial Intelligence (AI)
- Trial name
- NCT06905782
- Testing
- AI chatbot study arm, Traditional counselling study arm
- Where
- Malaysia
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Light Sensitivity
"Eye Protection After Mydriatic Use for ROP Screening: Impact on Vitals Signs and Pain Scores"
Pupillary dilation induced by mydriatic agents during Retinopathy of Prematurity exams can persist for hours. Despite regular use of eye protection for mydriatic-induced light sensitivity for infants, children and adults, eye…
- Trial name
- NCT01860534
- Testing
- eye covers
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Obstructive Sleep Apnea
Comparison of Methodology Proposed by the SFAR for the Detection by Videoconference of Obstructive Sleep Apnea.
The SFAR (French society of anesthesiology and ICU) proposed a method to detect OSA (Obstructive Sleep Apnea) patients via videoconference.
- Trial name
- NCT05711329
- Testing
- Accuracy
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Astes
Colorectal Cancer, Colorectal Neoplasm
A Stool DNA Test for Detection of Advanced Colorectal Neoplasia in Asymptomatic Chinese Community Population
to determine screening value of stool-based SDC2 DNA methylation test for advanced colorectal neoplasia in the asymptomatic Chinese community population.
- Conditions
- Colorectal Cancer, Colorectal Neoplasm, Advanced Adenoma, Adenoma
- Trial name
- NCT04786704
- Testing
- Stool-based SDC2 DNA methylation test, quantitative Fecal immunochemical test
- Where
- China
- Volunteers
- 12,106 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Type 1 Diabetes, Celiac Disease
General Population Level Estimation for Type 1 Diabetes Risk in Children During Routine Care Delivery
In partnership with Helmsley Charitable Trust, the Sanford PLEDGE Study is a large-scale, observational, feasibility study of general population screening for T1D and celiac autoantibodies.
- Trial name
- PLEDGE (NCT04477928)
- Testing
- Sera and whole blood sampling, Differential Gene Expression (DGE)
- Where
- 4 sites in United States
- Volunteers
- 33,000 people, healthy volunteers welcome
- Sponsor
- Sanford Health
Colonoscopy
Comparing Warm Versus Cool Temperature Water During Colonoscopy
The purpose of this study will be to determine if the temperature of water used during insertion of colonoscopy makes a difference in patient discomfort and sedation requirements.
- Trial name
- NCT01322724
- Testing
- Warm vs Cool water
- Where
- United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- OHSU Knight Cancer Institute
Cervical Cancer, Stigma
Effectiveness of a Cervical Cancer Stigma Reduction Intervention Program on Cancer Stigma Score and Cervical Cancer Screening Uptake in Nepal
It is an interventional study to assess the effectiveness of the cervical cancer stigma reduction intervention on cancer stigma score and cervical cancer screening uptake in Nepal
- Conditions
- Cervical Cancer, Stigma, Screening
- Trial name
- NCT05489978
- Testing
- "Cervical Cancer Stigma Reduction Intervention"
- Where
- Nepal
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- Kathmandu University School of Medical Sciences
Gastric Cancer
Multi-Omics Noninvasive Inspection of TumOr Risk for Gastric Cancer
This is a prospective, case-control study intended to develop and validate a blood-based multi-omics assay and computational model for early detection of gastric cancer.
- Trial name
- MONITOR- GAC (NCT04947995)
- Testing
- ctDNA multi-omics test
- Where
- China
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- GeneCast Biotechnology Co., Ltd.
Glaucoma
Screening Protocol
The objective of this study is to collect data for the development and validation a screening process using aggregate data. In this study, data collection will encompass both retrospective and prospective approaches across…
- Trial name
- NCT06135727
- Testing
- Maestro2 OCT
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Topcon Corporation
Audio-Visual Triage System, Anxiety Levels
Innovation of Audio-Visual Triage System in Combating the Spread of COVID-19 Infection and Its Efficacy: A Novel Strategy
During the novel coronavirus pandemic, also known as SARS-CoV-2 or COVID-19 pandemic, frontline healthcare professionals suffered psychological as well as pathological trauma due to the lack of preparation to cope with this…
- Conditions
- Audio-Visual Triage System, Anxiety Levels, COVID-19 Spread, GAD-7 Score
- Trial name
- NCT04621214
- Testing
- Audio-Visual Triage System (AVT)
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Lahore
Preterm Birth
Effectiveness of Targeted Cervical Length Screening Guided by a Preterm Birth Risk Scoring System in Reducing the Rate of Preterm Birth
This cluster non-randomized controlled trial aims to evaluate the effectiveness and feasibility of a risk score-guided targeted cervical length screening strategy for the prevention of spontaneous preterm birth in routine…
- Trial name
- NCT07415070
- Testing
- Preterm birth risk scoring system, Transvaginal ultrasound cervical length measurement, Vaginal Progesterone
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Ningbo University
Colorectal Cancer, Colorectal Neoplasms
Exploring the Risk Factors for Colorectal Cancer in Our General Population Using Asian Pacific Screening Score: a Survey From Pakistan
In Pakistan, due to the lack of a National based cancer registry exact number of CRC cases is unknown. However, minimal data that is present in literature shows an increase in CRC cases with a concerning increase in incidence in…
- Trial name
- NCT05617378
- Where
- Pakistan
- Volunteers
- 558 people, healthy volunteers welcome
- Sponsor
- Sindh Institute of Urology and Transplantation
Biliary Atresia, Neonatal Cholestasis
Development and Validation of a Screening Score for the Biliary Atresia in Infantile Cholestasis: A Prospective Study
Better survival and prognosis of biliary atresia (BA) depend on early diagnosis and timely Kasai portoenterostomy. Identifying BA from other causes of infantile cholestasis at early stage of the disease still remains a major…
- Conditions
- Biliary Atresia, Neonatal Cholestasis, Infantile Hepatitis Syndrome
- Trial name
- NCT03842150
- Testing
- biliary atresia screen score
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Healthy Volunteers, Physical Fitness
Effects of 8-Week Mat Pilates and Reformer Pilates Exercises on Functional Movement Screen Scores and Joint Range of Motion in Recreationally Active Males
The goal of this clinical trial is to compare how 8 weeks of Mat Pilates and Reformer Pilates affect movement quality and joint flexibility in active young men.
- Trial name
- PILATES-FMS (NCT07869862)
- Testing
- Reformer Pilates Training, Mat Pilates Training
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University