Clinical trials: Seasonal Affective Disorder
Major Depressive Disorder
Light Therapy for Elderly Depression
The purpose of this study is to investigate the following two hypotheses: 1. Treatment with bright light improves their sleep, mood, concentration and self-sufficiency of elderly depressed subjects.
- Trial name
- NCT00332670
- Testing
- 10.000lux blue 1 hour every day during three weeks, 50lux dim red 1 hour every day during three weeks
- Where
- Netherlands
- Volunteers
- 89 people
- Sponsor
- GGZ Buitenamstel
Seasonal Affective Disorder
30-Minute Light Exposure for the Treatment of Seasonal Affective Disorder
The primary objective of this study is to evaluate the effect of light therapy using a narrow 467nm light compared to a 580nm light in subjects with Seasonal Affective Disorder (SAD).
- Trial name
- SAD (NCT01462305)
- Testing
- goLITE, Control
- Where
- 4 sites in United States
- Volunteers
- 35 people
- Sponsor
- Philips Respironics
Seasonal Affective Disorder (SAD)
Transcranial Bright Light Therapy in Seasonal Affective Disorder (SAD)
Bright light therapy (BLT) has been found to be effective in treatment of seasonal affective disorder (SAD). The mechanism of action of conventional BLT in the treatment of SAD is under debate.
- Trial name
- SAD3 (NCT01784705)
- Testing
- Transcranial bright light therapy
- Where
- Finland
- Volunteers
- 60 people
- Sponsor
- University of Oulu
Seasonal Affective Disorder
Bright Light Therapy in Seasonal Affective Disorder (SAD)
The aim of this study is to investigate the efficacy of bright light therapy in SAD. This is a placebo-controlled, double-blind randomized controlled trial (RCT).
- Trial name
- VAHAVA (NCT01030276)
- Testing
- Bright light therapy
- Where
- Finland
- Volunteers
- 60 people
- Sponsor
- University of Oulu
Seasonal Affective Disorder, Vitamin D3
The Role of Vitamin D Supplementation on Well Being and Symptoms of Depression During the Winter Season in Health Service Staff
The purpose of this study is to investigate whether vitamin D3 (70 micrograms) is better than placebo in preventing depression symptoms among employees in health care
- Conditions
- Seasonal Affective Disorder, Vitamin D3, Mental Health, Dietary Supplement
- Trial name
- D3-vit-SAD (NCT01462058)
- Testing
- Vitamin D3
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Connie Thuree Nielsen, consultant, MD, ph.d
Depression
Predicting Effectiveness of Light Treatment for Winter Seasonal Affective Disorder
This study will evaluate a possible tool for predicting future effectiveness of bright light in treating seasonal affective disorder, winter subtype, and will examine secondary effects of bright light on cardiovascular risk…
- Trial name
- NCT00742365
- Testing
- Bright light
- Volunteers
- 41 people
- Sponsor
- University of Maryland, Baltimore
Seasonal Affective Disorder
Optimizing Long-Term Outcomes for Winter Depression With CBT-SAD and Light Therapy
Major depression is a highly prevalent, chronic, and debilitating mental health problem with significant social cost that poses a tremendous economic burden.
- Trial name
- NCT03691792
- Testing
- Cognitive-Behavioral Therapy (CBT-SAD), Light Therapy
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- University of Vermont
Major Depressive Disorder
Efficacy and Safety of Light Therapy in the Treatment of Non-seasonal Depressive Disorder in Chinese Population
Depression is a kind of mental illness with high incidence, high recurrence and high disability. But so far, treatment remission rates for depression remain low. Therefore, it is necessary to develop more new treatments.
- Trial name
- NCT05499117
- Testing
- Light terapy, pseudo-light therapy
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Shanghai Mental Health Center
Seasonal Affective Disorder, Visual Impairment
Seasonal Affective Disorder and Visual Impairment
As a subtype of major depressive disorder, seasonal affective disorder (SAD) or winter depression causes severe reductions in both quality of life and productivity and results in high morbidity and frequent sick leave (1).
- Trial name
- NCT03403959
- Testing
- light therapy
- Where
- Denmark
- Volunteers
- 18 people
- Sponsor
- Psychiatric Centre Rigshospitalet
Seasonal Affective Disorder
Low Intensity 'Blue Light' Treatment of Seasonal Affective Disorder
One of the most frequently investigated hypothesis of the pathophysiology underlying Seasonal Affective Disorder(SAD) or so called winter depression is a disturbance of circadian rhythms.
- Trial name
- NCT01149135
- Testing
- Blue enriched light with a low intensity, standard light treatment
- Volunteers
- 22 people
- Sponsor
- University Medical Center Groningen
Seasonal Affective Disorder, Major Depressive Disorder
Investigation of Seasonal Variations of Brain Structure and Connectivity in SAD
Seasonal Affective Disorder (SAD) is a subtype of Major Depressive Disorder, characterized by a recurrent temporal relationship between the season of year, the onset and the remission of a major depressive episode.
- Conditions
- Seasonal Affective Disorder, Major Depressive Disorder, Neuroimaging
- Trial name
- NCT03313674
- Testing
- Bright Light Therapy
- Where
- Canada
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Seasonal Affective Disorder (SAD)
Prevention of Seasonal Affective Disorder
A Placebo Controlled Study Evaluating The Effectivess Of Medication In Preventing Seasonal Affective Disorder
- Trial name
- NCT00046449
- Testing
- Investigational Seasonal Affective Disorder (SAD) Drug
- Where
- 54 sites in United States, Canada
- Sponsor
- GlaxoSmithKline
Seasonal Affective Disorder (SAD)
Virtual Reality Digital Therapeutics for Seasonal Affective Disorder
Seasonal Affective Disorder (SAD) is commonly treated with bright light therapy. Virtual reality (VR) is an immersive computer-generated environment, which has been used to treat mental health difficulties, such as depression…
- Trial name
- VR-SAD (NCT07161570)
- Testing
- Virtual Reality (VR) Intervention, Light Box (LB) intervention
- Volunteers
- 60 people
- Sponsor
- Anglia Ruskin University
Seasonal Affective Disorder
Influence of Light Exposure on Cerebral MAO-A in Seasonal Affective Disorder and Healthy Controls Measured by PET
This study aims to assess differences in monoamine oxidase A (MAO-A) distribution in the brain between seasonal affective disorder patients and healthy controls using positron emission tomography.
- Trial name
- NCT02582398
- Testing
- Light Therapy
- Where
- Austria
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Seasonal Affective Disorder (SAD), Winter Depression
Cognitive-behavioral Therapy vs. Light Therapy for Preventing SAD Recurrence
Major depression is a highly prevalent, chronic, and debilitating mental health problem with significant social cost that poses a tremendous economic burden.
- Conditions
- Seasonal Affective Disorder (SAD), Winter Depression, Major Depressive Disorder, Recurrent, With Seasonal Pattern
- Trial name
- NCT01714050
- Testing
- Cognitive-Behavioral Therapy (CBT), Light Therapy (LT)
- Where
- United States
- Volunteers
- 177 people
- Sponsor
- University of Vermont
Seasonal Affective Disorder, Depression
Cognitive Behavioral Therapy for the Treatment of Seasonal Affective Disorder (SAD)
This study will assess the effectiveness of cognitive behavioral therapy (CBT) in treating seasonal affective disorder (SAD), commonly called the "winter blues."
- Trial name
- NCT00076245
- Testing
- Light Therapy, Cognitive behavioral therapy (CBT)
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Seasonal Affective Disorder
Bright Light Therapy in Seasonal Affective Disorder (SAD)
Bright light therapy (BLT) is widely accepted as first-line treatment of seasonal affective disorder (SAD). However, the mechanism of action of BLT is still widely unknown.
- Trial name
- NCT01293409
- Testing
- Transcranial Brain-Targeted Bright Light Treatment
- Where
- Finland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Oulu
Bipolar Depression
Bright Light Therapy in the Treatment of Non-seasonal Bipolar Depression
Bipolar disorder (BD) is a severe brain disorder characterized by the recurrence of mood episodes. Depressive episodes in BD are frequently refractory and clinicians have few treatment options.
- Trial name
- LUBI (NCT03396744)
- Testing
- Light
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Idiopathic Hypersomnia, Mood Disorder
Psychiatric Co-morbidities and Socio-demographic Characteristics in Patients With Idiopathic Hypersomnia
This is a study of only patients with idiopathic hypersomnia. It is a rare and still poorly understood pathology. In clinical practice, we have found that the treatment and care offered were not always effective.
- Conditions
- Idiopathic Hypersomnia, Mood Disorder, Bipolar Disorder
- Trial name
- HYPERSOMNPSY (NCT05778721)
- Testing
- respond to questionnaires by telephone
- Where
- France
- Volunteers
- 22 people
- Sponsor
- University Hospital, Toulouse
Depression
Treating Seasonal Depression With Daylight
A seasonal pattern in the on- and offset of depressive episodes in recurrent depressive disorder is prevalent at latitudes with large summer-winter differences in daylength.
- Trial name
- DLS (NCT07877402)
- Testing
- Outdoor, Indoor
- Where
- 2 sites in Denmark
- Volunteers
- 150 people
- Sponsor
- Klaus Martiny