Clinical trials: Seasonal Affective Disorder (SAD)
Seasonal Affective Disorder
A Trial of Negative Ion Generation Versus Light-Emitting Diode Phototherapy for Seasonal Affective Disorder (SAD)
This is a randomized, controlled clinical trial of inactivated negative ion generation or light-emitting photodiode therapy for Seasonal Affective Disorder (SAD, winter depression), for subjects with a DSM IV diagnosis of Major…
- Trial name
- NCT00809523
- Testing
- Negative Ion Generator, Light-emitting Photodiode light treatment device
- Where
- 8 sites in United States, Canada and 1 more
- Volunteers
- 106 people
- Sponsor
- Yale University
Seasonal Affective Disorder (SAD)
Virtual Reality Digital Therapeutics for Seasonal Affective Disorder
Seasonal Affective Disorder (SAD) is commonly treated with bright light therapy. Virtual reality (VR) is an immersive computer-generated environment, which has been used to treat mental health difficulties, such as depression…
- Trial name
- VR-SAD (NCT07161570)
- Testing
- Virtual Reality (VR) Intervention, Light Box (LB) intervention
- Volunteers
- 60 people
- Sponsor
- Anglia Ruskin University
Seasonal Affective Disorder
Optimizing Long-Term Outcomes for Winter Depression With CBT-SAD and Light Therapy
Major depression is a highly prevalent, chronic, and debilitating mental health problem with significant social cost that poses a tremendous economic burden.
- Trial name
- NCT03691792
- Testing
- Cognitive-Behavioral Therapy (CBT-SAD), Light Therapy
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- University of Vermont
Seasonal Affective Disorder
Effects of Season on Melatonin Secretion in Healthy Men and Women and Patients With Seasonal Affective Disorder
As the seasons change during the course of the year, many animals show major changes in their behavior and physiology. Many of these changes are triggered by changes in the length of time each night that the pineal gland produces…
- Trial name
- NCT00001485
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Seasonal Affective Disorder, Depression
Cognitive Behavioral Therapy for the Treatment of Seasonal Affective Disorder (SAD)
This study will assess the effectiveness of cognitive behavioral therapy (CBT) in treating seasonal affective disorder (SAD), commonly called the "winter blues."
- Trial name
- NCT00076245
- Testing
- Light Therapy, Cognitive behavioral therapy (CBT)
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Depressive Disorder
Seasonal Affective Depression (SAD) Study
A placebo controlled study evaluating the effectiveness of medication in preventing winter depressive episodes in patients with a history of Seasonal Affective Disorder
- Trial name
- NCT00069459
- Testing
- Extended-release Bupropion Hydrochloride
- Where
- 48 sites in United States
- Volunteers
- 250 people
- Sponsor
- GlaxoSmithKline
Seasonal Affective Disorder
Environmental Treatment for Seasonal Affective Disorder (SAD)
The purpose is to study treatments of Seasonal Affective Disorder (SAD).
- Trial name
- NCT00139997
- Testing
- Litebook treatment devices, Inactivated negative ion generator
- Where
- 5 sites in United States, Canada and 1 more
- Volunteers
- 26 people
- Sponsor
- Yale University
Seasonal Affective Disorder, Major Depressive Disorder
Investigation of Seasonal Variations of Brain Structure and Connectivity in SAD
Seasonal Affective Disorder (SAD) is a subtype of Major Depressive Disorder, characterized by a recurrent temporal relationship between the season of year, the onset and the remission of a major depressive episode.
- Conditions
- Seasonal Affective Disorder, Major Depressive Disorder, Neuroimaging
- Trial name
- NCT03313674
- Testing
- Bright Light Therapy
- Where
- Canada
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Seasonal Affective Disorder
Blue Enriched Versus Standard Light Treatment for Seasonal Affective Disorder(SAD)
One of the most frequently investigated hypothesis of the pathophysiology underlying Seasonal Affective Disorder(SAD) or so called winterdepression is a disturbance of circadian rhythms.
- Trial name
- NCT01048294
- Testing
- Original Energy Light,, Original Energy Light prototype
- Where
- Netherlands
- Volunteers
- 52 people
- Sponsor
- University Medical Center Groningen
Seasonal Affective Disorder
Bright Light Therapy in Seasonal Affective Disorder (SAD)
The aim of this study is to investigate the efficacy of bright light therapy in SAD. This is a placebo-controlled, double-blind randomized controlled trial (RCT).
- Trial name
- VAHAVA (NCT01030276)
- Testing
- Bright light therapy
- Where
- Finland
- Volunteers
- 60 people
- Sponsor
- University of Oulu
Seasonal Affective Disorder, Vitamin D3
The Role of Vitamin D Supplementation on Well Being and Symptoms of Depression During the Winter Season in Health Service Staff
The purpose of this study is to investigate whether vitamin D3 (70 micrograms) is better than placebo in preventing depression symptoms among employees in health care
- Conditions
- Seasonal Affective Disorder, Vitamin D3, Mental Health, Dietary Supplement
- Trial name
- D3-vit-SAD (NCT01462058)
- Testing
- Vitamin D3
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Connie Thuree Nielsen, consultant, MD, ph.d
Seasonal Affective Disorder, Healthy
Clinical Trial of Propranolol for Seasonal Affective Disorder
The purpose of this study is to determine what dose of a new timed-release tablet of the drug propranolol will reduce secretion of the hormone melatonin in healthy volunteers.
- Trial name
- NCT00016666
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Seasonal Affective Disorder (SAD), Winter Depression
Cognitive-behavioral Therapy vs. Light Therapy for Preventing SAD Recurrence
Major depression is a highly prevalent, chronic, and debilitating mental health problem with significant social cost that poses a tremendous economic burden.
- Conditions
- Seasonal Affective Disorder (SAD), Winter Depression, Major Depressive Disorder, Recurrent, With Seasonal Pattern
- Trial name
- NCT01714050
- Testing
- Cognitive-Behavioral Therapy (CBT), Light Therapy (LT)
- Where
- United States
- Volunteers
- 177 people
- Sponsor
- University of Vermont
Seasonal Affective Disorder
30-Minute Light Exposure for the Treatment of Seasonal Affective Disorder
The primary objective of this study is to evaluate the effect of light therapy using a narrow 467nm light compared to a 580nm light in subjects with Seasonal Affective Disorder (SAD).
- Trial name
- SAD (NCT01462305)
- Testing
- goLITE, Control
- Where
- 4 sites in United States
- Volunteers
- 35 people
- Sponsor
- Philips Respironics
Seasonal Affective Disorder
Ramelteon in the Treatment of Sleep and Mood in Patients With Seasonal Affective Disorder
The purpose of this study is to determine whether treating sleep difficulties in patients with seasonal affective disorder also improves their depressive symptoms.
- Trial name
- SAM-SAD (NCT00502320)
- Testing
- Ramelteon
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Lehigh Valley Hospital
Seasonal Affective Disorder
Light-Emitting Diode (LED) Light for Seasonal Affective Disorder (SAD) Treatment
Recurrent fall/winter major depression (known as Seasonal Affective Disorder (SAD)) is a prevalent and disruptive disorder whose pathophysiological basis is unknown, but several hypotheses attribute a causal role to the circadian…
- Trial name
- NCT00114322
- Testing
- light exposure from LED source at narrow 468 nm or broader 400-700 nm wavelength
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Brigham and Women's Hospital
Seasonal Affective Disorder, Mood Disorders
Clinical Trials of Three Non-Drug Treatments for Winter Depression (SAD)
We are offering non-pharmacologic therapy for alleviation of symptoms associated with depressed mood that recurs annually in fall or winter.
- Conditions
- Seasonal Affective Disorder, Mood Disorders, Depression
- Trial name
- NCT00006517
- Testing
- bright light box, dawn simulator, high-output negative ion generator
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- New York State Psychiatric Institute
Seasonal Affective Disorder (SAD)
Prevention of Seasonal Affective Disorder
A Placebo Controlled Study Evaluating The Effectivess Of Medication In Preventing Seasonal Affective Disorder
- Trial name
- NCT00046449
- Testing
- Investigational Seasonal Affective Disorder (SAD) Drug
- Where
- 54 sites in United States, Canada
- Sponsor
- GlaxoSmithKline
Seasonal Affective Disorder
Bright Light Therapy in Seasonal Affective Disorder (SAD)
Bright light therapy (BLT) is widely accepted as first-line treatment of seasonal affective disorder (SAD). However, the mechanism of action of BLT is still widely unknown.
- Trial name
- NCT01293409
- Testing
- Transcranial Brain-Targeted Bright Light Treatment
- Where
- Finland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Oulu
Seasonal Affective Disorder (SAD)
Transcranial Bright Light Therapy in Seasonal Affective Disorder (SAD)
Bright light therapy (BLT) has been found to be effective in treatment of seasonal affective disorder (SAD). The mechanism of action of conventional BLT in the treatment of SAD is under debate.
- Trial name
- SAD3 (NCT01784705)
- Testing
- Transcranial bright light therapy
- Where
- Finland
- Volunteers
- 60 people
- Sponsor
- University of Oulu