Clinical trials: Secondary Headache Disorders
Chronic Pain, Acute Pain
Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA
This study relies on the use of a smartphone application (SOMA) that the investigators developed for tracking daily mood, pain, and activity status in acute pain, chronic pain, and healthy controls over four months.The primary…
- Conditions
- Chronic Pain, Acute Pain, Post Operative Pain, Fibromyalgia, Primary
- Trial name
- NCT05754190
- Testing
- SOMA pain manager smartphone application
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Brown University
Post-Dural Puncture Headache
Comparing the Effects of Ondansetron Versus Dexamethasone on the Incidence of Post-dural Puncture Headache (PDPH) , Nausea and Vomiting After Spinal Anaesthesia of Parturients Undergoing Caesarean Section
Comparing dexamethasone and ondanestrone injection in ncidence of postdural puncture headache and post-partum nausea and vomiting
- Trial name
- NCT05202574
- Testing
- Intravenous drug
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Minia University
Medication Overuse Headache
Is Detoxification Needed in Medication-overuse Headache?
Medication-overuse headache (MOH) is a disabling condition, yet treatable. According to European guidelines and based on evidence, multidisciplinary detoxification is the first choice of treatment for MOH.
- Trial name
- DEFINE3 (NCT02993289)
- Testing
- Different well-known treatments
- Where
- Denmark
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Cervicogenic Headache
Comparative Effects Of Eye-Cervical Re-Education Exercises And Pressure Biofeedback Training Of Deep Cervical Flexors In Cervicogenic Headache
Cervicogenic headache (CGH) is a secondary headache that originates from dysfunction in the upper cervical spine, particularly the atlanto-occipital and C1-C3 segments, and is perceived in one or more regions of the head and/or…
- Trial name
- NCT07526025
- Testing
- Eye cervical re-education exercises, Pressure biofeedback training group
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Foundation University Islamabad
Cervicogenic Headache
Thrust Joint Manipulation and Reverse SNAGS (Sustained Natural Apophyseal Glides) in Cervicogenic Headache
The purpose of the study was to compare the effect of upper cervical thrust joint manipulation and reverse Sustained Natural apophyseal Glide on intensity of pain, pain pressure threshold, range of motion and headache disability…
- Trial name
- NCT04521218
- Testing
- Thrust Joint Manipulation, Reverse Sustained Natural apophyseal glides
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Post-Traumatic Headache
Study of Gammacore Sapphire for the Acute and Preventive Treatment of Post-Traumatic Headache (GAP-PTH)
The purpose of this single-center, prospective, randomized, double-blind, sham controlled, parallel-group study is to collect clinical data related to the safety and efficacy of vagus nerve stimulation for the acute and…
- Trial name
- NCT04071743
- Testing
- gammaCore Sapphire
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Medication-overuse Headache
Comparison of Two Detoxification Protocols for Treatment of Medication-overuse Headache
Medication-overuse headache (MOH) is a common, costly and disabling disorder affecting approximately 63 million people worldwide.
- Trial name
- MUM (NCT02903329)
- Testing
- Detoxification
- Where
- Denmark
- Volunteers
- 72 people
- Sponsor
- Danish Headache Center
PTSD, Military Activity
Art Therapy and Emotional Well Being in Military Populations With Posttraumatic Stress Symptoms
Art therapy is used across the Military Health System for treatment of posttraumatic symptoms, but there is limited research on how art therapy is able to restore emotional expression and regulation in service members.
- Conditions
- PTSD, Military Activity, Post-Traumatic Headache, Posttraumatic Stress Disorder
- Trial name
- NCT05414708
- Testing
- Art Therapy
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Walter Reed National Military Medical Center
Dry Needling, Dry Cupping
Dry Needling Versus Dry Cupping on Pain and Disability in Cervicogenic Headache Patients
This study aims to compare the added effects of dry needling and dry cupping to conventional physical therapy on headache pain intensity, headache frequency, headache duration, upper cervical range of motion, and disability…
- Conditions
- Dry Needling, Dry Cupping, Cervicogenic Headache
- Trial name
- NCT06689371
- Testing
- Group A (Dry Needling), Group B (Dry cupping), Group C (control)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cairo University
Migraine Disorders, Medication Overuse Headache
tDCS in Chronic Migraine With Medication Overuse (Edisom)
Transcranial direct current stimulation (tDCS) was suggested to provide beneficial effects in chronic migraine (CM), a condition often associated with medication overuse (MO) for which no long-term therapy is available.
- Trial name
- Edisom (NCT04228809)
- Testing
- tDCS
- Volunteers
- 135 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Medication Overuse Headache
Orbitofrontal Cortex (OFC) Influence on Addictive Medication Overuse Headache (MOH) Deriving From Migraine
Medication Overuse Headache (MOH) is an illness affecting about 1,5 % of the general population. It is characterized by chronic headache occurring for at least 15 days a month, by a use of antimigraine drugs during at least 3…
- Trial name
- MOH-PET (NCT00833209)
- Testing
- PET (withdrawal), Imaging
- Where
- 2 sites in France
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Post Traumatic Headache, Chronic Daily Headache
Yoga Training for Returning Veterans With Headache
The objective of the study is to evaluate the efficacy of a yoga treatment for veterans with mild post-traumatic and chronic tension-type headaches.
- Trial name
- NCT01993069
- Testing
- Iyengar-based Yoga Training
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, Los Angeles
Migraine Disorders
Role of Ultrasound Guide Greater Occipital Nerve Block at Second Cervical Vertebra in Migraine Headache Prophylaxis
The goal of this randomized controlled study in Thailand. is to find if there is a role of local anesthetic greater occipital nerve block at Cervical spine level 2 under ultrasound guide in prophylaxis of episodic migraine and…
- Trial name
- NCT06432127
- Testing
- Bupivacaine
- Where
- Thailand
- Volunteers
- 108 people
- Sponsor
- Mahidol University
Cervicogenic Headache
Comparative Effects of Back School Based Intervention Versus Cranio-Cervical Muscle Training in Computer Users With Cervicogenic Headache
The aim of the study is to compare Back School Based Intervention with Cranio- Cervical muscle training in participants with Cervicogenic headache.
- Trial name
- NCT07327827
- Testing
- Back School Based Intervention, Cranio-Cervical muscle Training
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Headache Disorders, Central Nervous System Diseases
Is Sphenopalatine Ganglion Block Treatment Effective on Postspinal Headaches
This study evaluates effect of sphenopalatine ganglion block in post dural puncture headache. Half of participants will receive standard supportive treatment and other half of patients will be performed sphenopalatine ganglion…
- Trial name
- SPG (NCT03512977)
- Testing
- sphenopalatine ganglion block, conservative treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Derince Training and Research Hospital
Cervicogenic Headache
McKenzie Method of Mechanical Diagnosis and Therapy for Management of Cervicogenic Headache: A Prospective Case Series
The goal of this study is to examine the effectiveness the Mechanical Diagnosis and Therapy (MDT) approach for the management patients with neck related headache that are referred to a hospital based out-patient physical therapy…
- Trial name
- NCT05212844
- Testing
- Musculoskeletal Physical Therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Faith Regional Health Services
Persistent Post-concussive Symptoms, Post Traumatic Headache
SPINEPASS: SPINE Self-management Techniques for Persistent Headache After Concussion: Physical Therapy Targeting Autonomic and Dura Mater Function.
This is a prospective randomized controlled trial comparing two different physical therapy approaches to the treatment of posttraumatic headache with autonomic symptoms.
- Trial name
- SPINEPASS (NCT06882239)
- Testing
- SPINEPASS Physical Therapy, Standard Physical Therapy
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- The University of Queensland
Cervicogenic Headache, Neck Pain Musculoskeletal
Mangement of Cervicogenic Headache by Maual Therapy
This study aims to investigate immediate and short-term effect of combining suboccipital myofascial release with Maitland mobilization techniques on headache intensity, duration, and frequency, CFRT, upper cervical ROM, general…
- Trial name
- NCT07310823
- Testing
- suboccipital myofacial release, maitland mobilization, combined myofacsial release with maitland mobilization
- Where
- Egypt
- Volunteers
- 57 people
- Sponsor
- Cairo University
Post-Dural Puncture Headache
EPiMAP Obstetrics: European Practices in the Management of Accidental Dural Puncture in Obstetrics
The aims of EPiMAP Obstetrics are: to identify risk factors for failure of epidural blood patch in the obstetric population for management of post dural puncture headache.
- Trial name
- EPiMAP (NCT02362828)
- Where
- Sweden
- Volunteers
- 1,110 people
- Sponsor
- European Society of Anaesthesiology
Cervicogenic Headache
Effect of Instrument-Assisted Soft Tissue Mobilization on Proprioception and Disability in Patients With Cervicogenic Headache
This study will be conducted to investigate the effect of instrument assisted soft tissue mobilization technique In pain intensity, frequency of headache, medication Uptake, Suboccipital movement in flexion and extension, rounded…
- Trial name
- IASTM (NCT05545423)
- Testing
- instrumented assisted soft tissue mobilization, traditional therapy
- Volunteers
- 80 people
- Sponsor
- Cairo University