Clinical trials: Secondary Lymphedema
Secondary Lymphedema
Scapulothoracic Stabilization and Postural Training in Upper Extremity Lymphedema
This single-center randomized controlled trial aims to investigate the effects of adding scapulothoracic stabilization and postural training to standard lymphedema care in women with secondary upper extremity lymphedema following…
- Trial name
- NCT07697495
- Testing
- Complex Decongestive Therapy, Scapulothoracic Stabilization and Postural Training
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Toros University
Arteriovenous Malformation, Hemangioma
Clinical Translation of a Novel Albumin-Binding PET Radiotracer 68Ga-NEB
This is an open-label whole-body PET/CT study for investigation of radiation dosimetry, plasma pharmacokinetics, biodistribution, safety and diagnostic performance of 68Ga-NEB in healthy volunteers and patients with suspected…
- Conditions
- Arteriovenous Malformation, Hemangioma, Neoplasms Lymph Nodes, Lymphedema
- Trial name
- NCT02496013
- Testing
- 68Ga-NEB
- Where
- China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Lipedema, Secondary Lymphedema
Complete Decongestive Therapy With Negative Pressure for Lipedema and Lymphedema Therapy
This study is designed to investigate the therapy outcomes from routine physical therapy in persons with lipedema and secondary limb lymphedema.
- Trial name
- NCT03634462
- Testing
- CDT with graded negative pressure
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Breast Neoplasms, Lymphedema
The Use of Selenium to Treat Secondary Lymphedema - Breast Cancer
The primary objective of this study to assess the effectiveness of selenium compared to placebo in reducing the lymphedema in-patients with breast cancer.
- Trial name
- NCT00188604
- Testing
- sodium selenite
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- University Health Network, Toronto
Breast Cancer Lymphedema
Axillary Reverse Mapping (ARM) in Breast Cancer Surgery to Prevent Lymphedema. (ARMtrial)
Breast cancer related lymphedema (BCRL) is a debilitating and distressing condition affecting approximately one out of five breast cancer survivors.
- Trial name
- NCT03333226
- Testing
- Axillary Reverse Mapping (ARM)
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- University Hospital of Ferrara
Lymphedema of Leg, Sensitisation
Effects of Complex Decongestive Therapy on Proprioception, Balance and Tactile Sense
The aim of this study is to investigate the effects of complex decongestive physiotherapy (CDP) on propriseception, balance and sensation in patients with secondary lymphedema that develops in the lower extremities after cancer…
- Conditions
- Lymphedema of Leg, Sensitisation, Balanced, Therapy-Associated Cancer
- Trial name
- NCT06204510
- Testing
- complex decongestive therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Selcuk University
Lymphedema
Prevention of Lymphedema Among Breast Cancer Patients Through Implementation of an Integrative Therapy Program (ITP)
Introduction: Breast cancer women who are treated with axillary node dissection are at increased risk for lymphedema - the lifetime risk in these women is estimated at 15-50% and the risk can significantly increase with…
- Trial name
- NCT02528539
- Testing
- ITP
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Huntington Memorial Hospital
Lymphedema, Obesity & Overweight
TECAR and ESWT in Obesity-Related Lower Limb Lymphedema
This randomized controlled trial evaluates the effectiveness of adding TECAR therapy or extracorporeal shock wave therapy (ESWT) to complex decongestive therapy (CDT) in the treatment of bilateral lower-limb lymphedema in…
- Trial name
- NCT07520942
- Testing
- Complex Decongestive Therapy, TECAR Therapy, Extracorporeal Shock Wave Therapy
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Applied Science Private University
Sentinel Lymph Node, Endometrial Cancer
Sentinel Node Detection in Endometrial Cancer: A Consolidation Study on Detection Rates of Metastatic Disease
Evaluation of removal of Sentinel lymph nodes only for detection of pelvic lymph node metastases in high risk and low risk endometrial cancer.
- Conditions
- Sentinel Lymph Node, Endometrial Cancer, Lymphedema
- Trial name
- NCT03838055
- Testing
- Injection of tracer ( ICG) and detection of sentinel lymph nodes
- Where
- Sweden
- Volunteers
- 362 people
- Sponsor
- Region Skane
Lymphedema, Secondary, Lymphedema of Upper Limb
The N-LVA Study: RCT Comparing LVA vs. Sham Surgery in Cancer-related Lymphedema
The goal of this randomized controlled trial is to compare the effectiveness and cost-effectiveness of lymphaticovenous anastomosis (LVA) with sham surgery for patients suffering from unilateral cancer-related lymphedema in…
- Conditions
- Lymphedema, Secondary, Lymphedema of Upper Limb, Lymphedema, Lower Limb, Lymphedema Arm
- Trial name
- NCT06082349
- Testing
- Lymphaticovenous anastomosis
- Where
- 3 sites in Netherlands
- Volunteers
- 110 people
- Sponsor
- Maastricht University Medical Center
Secondary Lymphedema
Lymphatic Function in Patients Who Have Undergone Breast Cancer Treatment
Protocol resume Swelling of tissue due to excess fluid, called lymphedema, is a common side effect of breast cancer treatment that requires lifelong treatment but in what way the treatment of breast cancer affects the lymphatic…
- Trial name
- LYFE-B (NCT03572998)
- Testing
- Indocyanine Green (ICG)
- Where
- Denmark
- Volunteers
- 28 people
- Sponsor
- University of Aarhus
Lymphedema
Study of Lymphatic Dysfunction in Primary and Secondary Lymphedema
Lymphedema is a disorder of the lymphatic vascular system characterized by impaired lymphatic return and swelling of the extremities and accumulation of undrained interstitial fluid/lymph that results in fibrosis and adipose…
- Trial name
- LYMPHODYS (NCT05629026)
- Testing
- Micro-biopsies
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Toulouse
Lymphedema, Secondary, Lymphedema of Upper Limb
LymphoPilot Test for Limb Lymphedema
The present study is a first-in-man, single arm, open-label, single center study to assess feasibility and safety of a novel implantable device, LymphoPilot, in patients suffering from secondary upper limb or lower lymphedema.
- Conditions
- Lymphedema, Secondary, Lymphedema of Upper Limb, Lymphedema Arm, Lymphedema of Leg
- Trial name
- NCT04858230
- Testing
- LymphoPilot
- Where
- Switzerland
- Volunteers
- 12 people
- Sponsor
- Lymphatica Medtech SA
Lymphedema of Upper Arm
Using an Adjustable Compression Garment for Secondary Upper Limb Lymphoedema
This is a pilot randomised controlled trial investigating the use of an adjustable compression garment in the treatment of patients with Breast Cancer related upper limb Lymphoedema.
- Trial name
- NCT04435639
- Testing
- Manual lymph drainage., Coban compression bandage.., Adjustable Compression Sleeve
- Where
- Ireland
- Volunteers
- 30 people
- Sponsor
- Institute of Technology, Sligo
Secondary Lymphedema
Imaging Biomarkers of Lymphatic Dysfunction
Persons with secondary arm and/or upper quadrant lymphedema following cancer therapies commonly are prescribed complete decongestive therapy as a course of management of their lymphedema.
- Trial name
- NCT03760744
- Testing
- CDT with Negative Pressure, CDT alone
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Vanderbilt University Medical Center
Breast Neoplasms
Effect of Preoperative Exercise on the Prevention of Secondary Lymphedema in Breast Cancer Patients
Research purpose: Lymphedema is a very common complication in breast cancer patients. However, since there is currently no curable treatment, it is important to prevent and reduce the severity of lymphedema.
- Trial name
- NCT06421285
- Testing
- Aerobic exercise, Strength training, Flexibility exercise
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Asan Medical Center
Pelvic Floor Disorder, Female Pelvic Floor Dysfunction
Late Side-effects After Cervical Cancer Treatment - Prevention and Treatment
Late side-effects following gynecological cancer are predominantly symptoms from the pelvic region originating from the bowels, urinary tract, lymphatic system, genitals and musculoskeletal system.
- Conditions
- Pelvic Floor Disorder, Female Pelvic Floor Dysfunction, Female Sexual Dysfunction, Female Urinary Incontinence
- Trial name
- NCT06786091
- Testing
- Pelvic floor muscle training rehabilitation
- Where
- 2 sites in Norway
- Volunteers
- 25 people
- Sponsor
- St. Olavs Hospital
Secondary Lymphedema
A Phase I Study With Lymfactin® in the Treatment of Patients With Secondary Lymphedema
Indicated for the Treatment of Secondary Lymphedema Associated with the Treatment of Breast Cancer. Primary objective is to evaluate the safety and tolerability of a single dose of Lymfactin® in patients with secondary lymphedema…
- Trial name
- NCT02994771
- Testing
- Lymfactin® [1 x 10E10 vp], Lymfactin® [1 x 10E11 vp]
- Where
- 3 sites in Finland
- Volunteers
- 15 people
- Sponsor
- Herantis Pharma Plc.
Lymphedema Arm
Lymphovenous Bypass Procedure for Secondary Prevention of Lymphedema in Breast Cancer
This study aims to evaluate the effectiveness of the Lymphovenous Bypass (LVB) procedure compared to physiotherapy alone as secondary prevention of lymphedema in breast cancer patients undergoing axillary lymph node dissection.
- Trial name
- NCT07233863
- Testing
- Lymphovenous bypass (LVB)
- Where
- Indonesia
- Volunteers
- 136 people
- Sponsor
- Dharmais National Cancer Center Hospital
Postmastectomy Lymphedema Syndrome, Breast Cancer Surgery Pain
Deep Learning for Musculoskeletal Complications in Breast Cancer
Survival after breast cancer has increased due to early diagnosis and advances in treatment methods. Musculoskeletal problems related to cancer and its treatment constitute a significant part of the daily practice of physiatrists…
- Conditions
- Postmastectomy Lymphedema Syndrome, Breast Cancer Surgery Pain, Osteoporosis Secondary, Shoulder Adhesive Capsulitis
- Trial name
- NCT07236658
- Testing
- physical examination
- Where
- Turkey (Türkiye)
- Volunteers
- 133 people
- Sponsor
- Ankara Etlik City Hospital