Clinical trials: Secondary Prevention
Coronary Artery Bypass Grafting, Secondary Preventions
Quality Measurement and Improvement Study of Surgical Coronary Revascularization: Secondary Prevention
The investigators have identified underuse of secondary prevention medications at discharge of patients underwent coronary artery bypass grafting (CABG) in China.
- Trial name
- MISSION-1 (NCT02430012)
- Testing
- Quality improvement strategies
- Where
- China
- Volunteers
- 10,009 people
- Sponsor
- China National Center for Cardiovascular Diseases
Stable Coronary Artery Disease
Prognostic Models for People With Stable Coronary Artery Disease
There is currently no published algorithm for secondary prevention prognosis of CHD that is representative of the England GP-registered population and that includes both symptomatic and asymptomatic patients (as identified…
- Trial name
- NCT01609465
- Where
- United Kingdom
- Volunteers
- 300,000 people
- Sponsor
- University College, London
Socioeconomic Status, Secondary Prevention
Socioeconomic Status, Secondary Prevention Activities and Recurrence After a Myocardial Infarction
This is a nationwide cohort study on real-world patients (n≈30,000) surviving a first myocardial infarction (MI) 2006-2013 and alive to attend a routine 1-year follow-up.
- Conditions
- Socioeconomic Status, Secondary Prevention, Myocardial Infarction, Cardiovascular Disease
- Trial name
- NCT04199663
- Volunteers
- 30,191 people
- Sponsor
- Karolinska Institutet
Infection Secondary to Surgical Procedure
Antibiotic Prophylaxis in Gynecologic Laparoscopy
Laparoscopy is a surgical procedure indicated for most gynecological pathologies and presents numerous advantages over laparotomy, among them lower rates of surgical site infection and less comorbidity feverish.
- Trial name
- NCT01991834
- Testing
- gynecologic laparoscopy, Cefazolin
- Where
- 2 sites in Brazil
- Volunteers
- 114 people
- Sponsor
- Universidade do Vale do Sapucai
Embolic Stroke of Undetermined Source
Embolic Stroke of Undetermined Source, Continuous Electrocardiography and Transthoracic ECHOcardiography in Hospitalized Patients With Ischemic Stroke
Transthoracic echocardiography (TTE) is recommended in patients with ischemic stroke when cardiac etiology is suspected to help plan secondary stroke management.
- Trial name
- ESECHO (NCT04808258)
- Testing
- C3+ Holter Monitor
- Where
- 2 sites in Denmark
- Volunteers
- 500 people
- Sponsor
- Herlev and Gentofte Hospital
Internet Addiction Prevention Among Higher Secondary School Students
Effect of TPB-Based Educational Intervention on Preventing Internet Addiction in Students
This quasi-experimental study evaluated a Theory of Planned Behavior-based educational intervention among higher secondary students in Kathmandu, Nepal.
- Trial name
- NCT07504978
- Testing
- Educational Intervention Package based on the Theory of Planned Behavior
- Where
- Nepal
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Manish Rajbanshi
Critical Limb Ischemia
External Compression Therapy for Secondary Prevention of Lower-Limb Loss and Cardiovascular Mortality
In this clinical research study the investigators will test the efficacy of an innovative, non-invasive methodology to reduce mortality and lower limb loss among high-risk medically-underserved patients with cardiovascular…
- Trial name
- ArtAssist (NCT02054416)
- Testing
- ArtAssist© Device
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Temple University
Childhood Malignant Fibrous Histiocytoma of Bone, Sarcoma
Glutamine in Preventing Oral Mucositis in Patients Receiving Chemotherapy for Sarcoma
RATIONALE: Glutamine may help prevent mucositis, or mouth sores, in patients receiving chemotherapy for sarcoma. It is not yet known whether glutamine is more effective than a placebo in preventing mucositis in patients receiving…
- Trial name
- NCT00334984
- Testing
- glutamine, chemoprotection, management of therapy complications
- Sponsor
- Children's Oncology Group
Uterine Fibroids (Leiomyoma)
FATIMA Trial: EGCG and Vitamin D3 for Prevention of Fibroid Recurrence
The aim of this randomized controlled clinical trial is to evaluate the efficacy of green tea (EGCG) and vitamin D3 supplementation in preventing uterine fibroid recurrence following fibroid removal.
- Trial name
- FATIMA (NCT07647198)
- Testing
- Vitamin D and Green Tea
- Where
- United Arab Emirates
- Volunteers
- 240 people
- Sponsor
- Sheikh Shakhbout Medical City
Nonfatal Myocardial Infarction, Coronary Death
Association Between Low Dose Acetylsalicylic Acid (ASA) and Proton Pump Inhibitors and Risk of Acute Myocardial Infarction or Coronary Death
The purpose of this study is to estimate the risk of myocardial infarction (MI)/coronary death associated with use of monotherapy low dose ASA (single antiplatelet) as well as concomitant use of monotherapy low dose ASA and…
- Trial name
- NCT01360047
- Where
- Spain
- Volunteers
- 39,513 people
- Sponsor
- AstraZeneca
Stroke, Transient Ischemic Attack
China Stroke Secondary Prevention Trial
The CSSPT study is a multi-center, randomized, double blinded, placebo-controlled secondary stroke prevention trial in China to determine whether the addition of folic acid and vitamin supplements will reduce recurrent stroke…
- Trial name
- CSSPT (NCT01317849)
- Testing
- Folic Acid, Vitamin B6, Vitamin B12
- Where
- China
- Sponsor
- Xijing Hospital
Mitral Valve Stenosis
Late Clinical Outcomes of Percutaneous Mitral Commissurotomy in Patients With Mitral Stenosis
In this retrospective cohort study, out of 220 patients who had undergone successful PTMC between 2006 and 2018, the clinical course of 186 patients could be successfully followed.
- Trial name
- NCT04112108
- Testing
- PTMC
- Where
- Iran
- Volunteers
- 220 people
- Sponsor
- Shiraz University of Medical Sciences
Postdural Puncture Headache
Role of Prophylaxis by Oral Fluid Supplementation in Prevention of Postdural Puncture Headache
Postdural puncture headache (PDPH) is defined, according to the International Headache Society, as any headache develops within 5 days after a lumbar puncture.
- Trial name
- PROPHYDRA (NCT02859233)
- Testing
- Lack of hyperhydration
- Where
- 4 sites in France
- Volunteers
- 554 people
- Sponsor
- Nantes University Hospital
Sarcoma, Soft Tissue Sarcoma
LMWH vs Aspirin for VTE Prophylaxis in Orthopaedic Oncology
Aspirin and low molecular weight heparin (LMWH) are both commonly employed pharmacologic methods of venous thromboembolism (VTE) prophylaxis after orthopaedic surgery.
- Conditions
- Sarcoma, Soft Tissue Sarcoma, Bone Sarcoma, Bone Metastases
- Trial name
- NCT03244020
- Testing
- Aspirin 325mg, Enoxaparin 40Mg/0.4mL Prefilled Syringe
- Where
- 10 sites in United States
- Volunteers
- 2,868 people
- Sponsor
- Massachusetts General Hospital
Online CBT Targeting Cardiac Anxiety
Online Cognitive Behavioral Therapy Targeting Cardiac Anxiety
The purpose of the present study is to evaluate an internet-delivered exposure-based cognitive behavioral therapy (CBT) protocol tailored for patients following myocardial infaction (MI) to increase Quality of Life (Qol) and…
- Trial name
- MI-CBT (NCT05580718)
- Testing
- MI-CBT
- Where
- Sweden
- Volunteers
- 96 people
- Sponsor
- Karolinska Institutet
Stroke
The Secondary Prevention Trial for Ischemic Stroke With DengzhanShengmai Capsule
In order to observe the secondary preventive effect of the Dengzhanshengmai capsule on ischemic stroke, the investigators hold the large randomized control trial (RCT).
- Trial name
- SPIRITDZSM1 (NCT00548223)
- Testing
- Dengzhan Shengmai capsule
- Where
- 84 sites in China
- Volunteers
- 3,143 people
- Sponsor
- Guangzhou University of Traditional Chinese Medicine
Bone Metastases
Dexamethasone for Pain Flare After Radiotherapy of Painful Bone metastasesZonMW 11510009
Cancer patients with pain due to bone metastases are often treated with external irradiation in order to reduce pain. However, patients may experience a temporary increase of pain shortly after irradiation, a so-called pain…
- Trial name
- NCT01669499
- Testing
- Dexamethasone acetate
- Where
- 2 sites in Netherlands
- Volunteers
- 411 people
- Sponsor
- UMC Utrecht
Secondary Prevention, CHD
National Tunisian Clinical Registry on CardioVascular Secondary Prevention Clinical
A non-interventional, national longitudinal multicenter study of CV secondary prevention in Tunisia
- Conditions
- Secondary Prevention, CHD, CV Risk
- Trial name
- NATURE STOP-CH (NCT07034274)
- Where
- Tunisia
- Volunteers
- 7,284 people
- Sponsor
- Dacima Consulting
Stroke
Iron Chelation in the Prevention of Secondary Degeneration After Stroke
Stroke is a major cause of disability over the world. While acute therapies have made huge progresses, the number of survivors leaving with clinical consequences of stroke is increasing.
- Trial name
- CHEL-IC (NCT05111821)
- Testing
- Magnetic Resonance Imaging (MRI), Deferiprone treatment
- Where
- 2 sites in France
- Volunteers
- 11 people
- Sponsor
- University Hospital, Bordeaux
Colorectal Cancer Liver Metastases, Colorectal Cancer
Aspirin in Colorectal Cancer Liver Metastases
The ASAC trial is a Scandinavian, multi-center, double-blinded, randomized, placebo-controlled study to determine whether adjuvant treatment with low-dose acetylsalicylic acid (ASA) can improve disease free survival in patients…
- Conditions
- Colorectal Cancer Liver Metastases, Colorectal Cancer, Liver Metastases
- Trial name
- ASAC (NCT03326791)
- Testing
- Acetylsalicylic acid
- Where
- 14 sites in Denmark, Norway and 1 more
- Volunteers
- 466 people
- Sponsor
- Oslo University Hospital