Clinical trials: Sedation
ANXIETY
Music Therapy and Sedation for Pain and Anxiety During Oocyte Retrieval
This study is a prospective observational investigation aimed at examining the effect of music intervention on anxiety and pain levels in patients undergoing the ovum pick-up (OPU) procedure under sedation at an IVF center.
- Trial name
- NCT07898358
- Where
- Turkey (Türkiye)
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Samsun University
Healthy
Remimazolam Versus Midaszolam for Sedation in Diagnostic Upper Gastrointestinal Endoscopy
The goal of this clinical trial is to compare the efficacy of remimazolam with midazolam in patients undergoing gastrointestinal endoscopy.
- Trial name
- NCT05836545
- Testing
- Remimazolam, Midazolam
- Where
- South Korea
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Anxiety, Pain
Bispectral Index and Clinical Parameters Evaluation in Dental Procedures
BACKGROUND: The degree of consciousness during nitrous oxide use is still a matter of concern for both dentists and anesthesiologists.
- Trial name
- BIS-01 (NCT02671578)
- Testing
- Nitrous Oxide
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Francisco Groppo
Dental Caries in Children, Pediatric Dental Sedation
Comparing Pediatric Dental Oral Sedation Outcomes With and Without Meperidine in Children Aged 3-7 Years
The primary objective of this randomized controlled trial is to assess the effects of oral sedation using midazolam and hydroxyzine with and without meperidine (a narcotic) on sedation outcomes in pediatric dental patients…
- Conditions
- Dental Caries in Children, Pediatric Dental Sedation, Meperidine, Hydroxyzine
- Trial name
- NCT04068948
- Testing
- Meperidine, Hydroxyzine, Midazolam
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Washington
Hypoxemia During Surgery
Prediction Model of Hypoxemia in Gastrointestinal Endoscopy Sedation
The incidence of hypoxemia during gastrointestinal endoscopy sedation is high, but there is still a lack of perfect prediction model of hypoxemia, which often leads to unpredictable respiratory complications.
- Trial name
- NCT06016998
- Where
- China
- Volunteers
- 1,023 people, healthy volunteers welcome
- Sponsor
- Sichuan Provincial People's Hospital
Satisfaction
Development and Validation of a Pediatric Procedural Sedation Satisfaction Survey
The quality of care associated with medical procedures, such as procedural sedation, has historically been assessed from the perspective of the healthcare professional, wherein the appropriateness of the services provided and the…
- Trial name
- NCT03468608
- Where
- Canada
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Orthopedic Disorder
Comparison of Remimazolam and Dexmedetomidine for Intraoperative Sedation
The purpose of this study is to compare the sedation efficacy of dexmedetomidine and remimazolam for intraoperative sedation during regional block.
- Trial name
- NCT05447507
- Testing
- Remimazolam, Dexmedetomidine
- Where
- South Korea
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Healthy Volunteers
Induction of Dreaming With EEG and Anesthesia in Healthy Adults
This open-label, randomized crossover study in healthy adults tests two propofol protocols to produce distinct experiential states.
- Trial name
- IDEA (NCT07198711)
- Testing
- Propofol - Emergence-from-LOR Protocol, Propofol - Light Sedation Protocol
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Stanford University
Oocyte Retrieval, Sedation, Conscious
Respiratory Depression During an Analgosedation Combining Remifentanil and Ketamine in TCI for Oocyte Retrieval
This study evaluates the effect of the addition of ketamine to a conscious sedation protocol including remifentanil during oocyte retrieval.
- Conditions
- Oocyte Retrieval, Sedation, Conscious, Ventilatory Depression
- Trial name
- NCT03458143
- Testing
- Ketamine 150 ng/ml, Remifentanil, Oocyte retrieval
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Erasme University Hospital
Anesthesia, In-vitro Fertilization
A Comparison of Sedation/Analgesia & LMA on Anxiety Level and Patient Satisfaction in In-Vitro Fertilization
In vitro fertilization (IVF) is a new expertise of our age. Anesthesia during the assisted reproduction technique is usually required during oocyte removal, which is one of the basic steps throughout the entire procedure.
- Conditions
- Anesthesia, In-vitro Fertilization, Analgesia
- Trial name
- IVF (NCT03814330)
- Testing
- State-Trait Anxiety Inventory, Quality of Recovery Score, Sedation/Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Inonu University
Electroencephalography, Melatonin
Sedation and Nursing Management in EEG Recording in Children
Electroencephalogram (EEG) has an important place in establishing the correct diagnosis, providing appropriate intervention, and predicting the prognosis in the long term in children.
- Conditions
- Electroencephalography, Melatonin, Chloral Hydrate, Hydroxyzine
- Trial name
- NCT05492812
- Testing
- Sedation and Nursing Management in EEG Recording in Children, Chloral Hydrate, Hydroxyzine
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Gastrointestinal Diseases
Propofol Versus Midazolam in Sedation for Upper and Lower Gastrointestinal Endoscopy.
There has been rapid growth in the number and complexity of gastrointestinal (GI) endoscopic procedures performed during the last decade.
- Trial name
- NCT06358131
- Testing
- Endoscopy
- Where
- 2 sites in Egypt
- Volunteers
- 656 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Gastric Emptying, Healthy
Effect of Dexmedetomidine on Gastric Emptying and Gastrointestinal Transit
The aim of the study is to determine the effect of dexmedetomidine infusion on gastric emptying and oro-caecal transit time in healthy volunteers, judged by measuring plasma paracetamol concentrations after paracetamol ingestion…
- Trial name
- GADEX (NCT01084473)
- Testing
- Dexmedetomidine, Morphine
- Where
- Finland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Turku
Choosing Better Drug Option for Sedation in Pediatric Population Intraoperatively
Comparison of Sedative Effect of Dexmedetomidine and Midazolam for TIVA
Comparison of sedative effects of dexmedetomidine and midazolam using ramsay sedation scores intraoperatively in children undergoing inguinal hernia repair.
- Trial name
- NCT05574179
- Testing
- Dexmedetomidine injection, Midazolam
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sheikh Zayed Medical College
Procedural Sedation, Colonoscopy
Effect of Discontinuing Propofol After Cecal Intubation on Patient's Psychomotor Recovery Following Colonoscopy
This study investigates whether discontinuing the continuous intravenous infusion of propofol immediately after cecal intubation would reduce the patient's recovery time without compromising their comfort or convenience.
- Conditions
- Procedural Sedation, Colonoscopy, Cecal Intubation Success Rate, Propofol Adverse Reaction
- Trial name
- NCT07168135
- Testing
- propofol (drug)
- Where
- Lebanon
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Pediatric Sedation, Clonidine Sedation
Premedication in Children: a Clinical Trial Comparing Oral Ketamine and Oral Clonidine With Respect to Sedation Level and Opioid Consumption in Pediatrics Undergoing Elective Lower Abdominal Day-case Surgery.
Aim of the work Is to compare between oral ketamine and oral clonidine regarding the level of sedation pre and postoperatively in addition the need of opioids administration intraoperative in children undergoing elective lower…
- Conditions
- Pediatric Sedation, Clonidine Sedation, Ketamine Sedation
- Trial name
- NCT07461376
- Testing
- Oral Clonidine (OC)
- Where
- Egypt
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Cairo University
Patient Satisfaction, Virtual Reality
Virtual Reality to Improve Satisfaction in Hysteroscopy Patients
This study aims to investigate whether viewing an immersive virtual reality (VR) image through a VR headset during elective hysteroscopy under Registered Nurse (RN) led sedation with fentanyl and midazolam plus local anesthesia…
- Conditions
- Patient Satisfaction, Virtual Reality, Hysteroscopy
- Trial name
- VIP (NCT04862598)
- Testing
- Oculus Virtual Reality
- Where
- Canada
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Pain Intensity Assessment
Pain Relief in Women Undergoing Oocyte Retrieval (OR) With Electro-acupuncture (EA) or Conscious Sedation (CS) in a Single Assisted Reproduction Centre.
This study aims to determine whether one can replace pain relief in women undergoing oocyte retrieval (OR) using electro-acupuncture (EA) instead of conscious sedation (CS).
- Trial name
- EA (NCT07041632)
- Testing
- electro-acupuncture, Conscious sedation
- Where
- Singapore
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Sedation for Children Undergoing MRI
A Comparison Between Oral Melatonin With Nasal Sevoflurane Versus Oral Chloral Hydrate With Nasal Sevoflurane in Sedation of Children Undergoing Brain MRI
The patients will be randomized into 2 equal groups by a computer-generated random numbers table, named group A, B. Group A: will receive oral Melatonin and nasal Sevoflurane.
- Trial name
- NCT06606899
- Testing
- Melatonin 3 MG, Chloral Hydrate, Sevoflurane
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Ketamine-Induced Mood Disorder
The Role of Ketamine and Dexmedetomidine in Opioid-Sparing Analgesia
Optimal multimodal opioid-sparing analgesic technique is considered as one of the most important Enhanced recovery pathways (ERPs) or enhanced recovery after surgery (ERAS) interventions that mitigate the undesirable effects of…
- Trial name
- NCT05474183
- Testing
- Ketamine
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Fayoum University Hospital