Clinical trials: Sedation During
Upper Airway Obstruction
A New Flexible Extended-Length Pharyngeal Airway for Deep Sedation
The purpose of this prospective pilot provider adoption study was to evaluate user experience a new airway device in adult patients with airway obstruction under deep sedation. Fifteen hospital systems served as testing sites.
- Trial name
- NCT04419883
- Testing
- McMurray Enhanced Airway
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- McMurray Medical Group, LLC
Procedural Sedation
Dexmedetomidine for Sedation During Radiological Interventional Procedures
Evaluation of the role of dexmedetomidine as a sole agent in sedating patients undergoing interventional radiological procedures and measuring its different outcome variables.
- Trial name
- Dexmed (NCT02180737)
- Testing
- Dexmeditomedine
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- National Cancer Institute, Egypt
Hypertension
The Effects of Dexmedetomidine to Postoperative Awakening and Extubation-related Changes in Blood Pressure
The postoperative removal of intubation tube induces a noticeable sympathic response and increase of blood pressure. The risk of complications is especially elevated with the patients having cardiac surgery.
- Trial name
- NCT01871129
- Testing
- Dexmedetomidine
- Where
- Finland
- Volunteers
- 50 people
- Sponsor
- Tampere University Hospital
Conscious Sedation
Propofol Sedation During Upper Endoscopy With and Without Topical Pharyngeal Anesthesia
It is unclear whether a topical pharyngeal anesthesia adds any benefit to the upper gastrointestinal endoscopy under a propofol sedation.
- Trial name
- NCT01081002
- Testing
- Lidocaine 10%, Diluted gentian root solution
- Where
- 2 sites in Switzerland
- Volunteers
- 294 people
- Sponsor
- University Hospital, Basel, Switzerland
Sedation
Clinical Study to Investigate the Efficacy and the Safety of DA-9501 in Sedation During the Surgery With Epidural Anesthesia or Spinal Anesthesia Without Intubation
The purpose of this study is to examine the efficacy and safety of DA-9501 (Dexmedetomidine) in patients who require sedation during the surgery that requires epidural or spinal anesthesia without intubation under monitored…
- Trial name
- NCT01438957
- Testing
- Dexmedetomidine hydrochloride
- Where
- 12 sites in Japan
- Volunteers
- 119 people
- Sponsor
- Pfizer
Pain Management, Injection Pain Prevention
Testing the Timing and Application of Virtual Reality Distraction During Knee Injections in a VA Pain Clinic
The goal of this clinical trial is to learn whether virtual reality (VR) can be added to routine knee injection appointments at a VA outpatient pain clinic without slowing down or disrupting clinic operations.
- Conditions
- Pain Management, Injection Pain Prevention, Virtual Reality, Feasibility Studies
- Trial name
- NCT07884851
- Testing
- Immersive Virtual Reality
- Volunteers
- 45 people
- Sponsor
- Atlanta VA Medical Center
Pregnant People, Anxiety
Remimazolam Versus Dexmedetomidine for Sedation During Neuraxial
Patients presenting for a scheduled cesarean delivery who require a neuraxial anesthetic will be randomized to receive intravenous remimazolam or dexmedetomidine for procedural sedation during the placement of their spinal or…
- Trial name
- NCT07651956
- Testing
- Remimazolam, Dexmedetomidine
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Sedation and Analgesia, Cholangiopancreatography, Endoscopic Retrograde
EEG and Pain Monitor Data Under Anesthesia to Study Pharmacodynamic Effects of Opioids and Sedatives
Recording and analyzing electroencephalogram (EEG) and continuous pain monitor data under anesthesia in order to investigating the pharmacodynamic effects of opioids and sedatives.
- Conditions
- Sedation and Analgesia, Cholangiopancreatography, Endoscopic Retrograde, Anesthesia, General
- Trial name
- SED-ERCP (NCT07211828)
- Testing
- high dose of alfentanil, low dose of alfentanil with propofol
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- Chi Kwan Fung
Biliary Tract Diseases, Pancreatic Diseases
Comparison Between Continuous Infusion and Intermittent Bolus Injection of Propofol for Deep Sedation During ERCP
The aim of this study is to compare sedation efficiency, safety and satisfaction by both endoscopist, assistants, and the patients between continuous infusion and intermittent bolus injection of propofol for deep sedation during…
- Trial name
- NCT01900938
- Testing
- Continuous infusion of propofol, Intermittent bolus injection of propofol, Midazolam
- Where
- South Korea
- Volunteers
- 210 people
- Sponsor
- Hanyang University
Hypoxemia, Complications
Capnography During Colonoscopy
In the study the value of capnography for avoiding complications during sedation for colonoscopy is evaluated.
- Trial name
- ColoCap (NCT01072487)
- Testing
- Capnography
- Where
- 3 sites in Germany
- Volunteers
- 760 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Anesthesia, Sedation
Gastro-laryngeal Tube During Transesophageal Echocardiography
To analyze the effects of the use of Gastro-laryngeal Tube on intraoperative and postoperative hemodynamics, procedure comfort, and cardiologist and patient satisfactions during transesophageal echocardiography.
- Conditions
- Anesthesia, Sedation, Analgesia, Airway Complication of Anesthesia
- Trial name
- GLT (NCT05272306)
- Testing
- Number of attempts for successful transesophageal echocardiography, A questionnaire for cardiologist satisfaction, A questionnaire for patient satisfaction
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Bezmialem Vakif University
Peripheral Nerve Block, Anxiety
Music vs Midazolam During Preop Nerve Block Placement - Part 2 Study On Anxiolytic Options Before Peripheral Nerve Blocks
This study is evaluating music vs midazolam as a means of anxiolysis for preoperative single-shot nerve block placement.
- Conditions
- Peripheral Nerve Block, Anxiety, Preoperative Anxiety
- Trial name
- NCT05610969
- Testing
- Music, Midazolam
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Pennsylvania
Gallbladder Disease, Gallstones
Effect of Benadryl Sedation During ERCP or EUS
The purpose of the study is to determine if adding Benadryl improves sedation for patients scheduled to undergo ERCP or EUS procedures.
- Conditions
- Gallbladder Disease, Gallstones, Pancreatitis, Abdominal Pain
- Trial name
- NCT00240123
- Sponsor
- University of Rochester
Procedural Sedation, Dreams
Personalized Music, Dreaming During Propofol Sedation
This randomized clinical trial will evaluate whether music delivered through closed-back headphones during intravenous propofol sedation affects dreaming and the overall sedation experience.
- Trial name
- NCT07638072
- Testing
- Preferred Music, Matched Non-preferred Music, Silence Control
- Where
- South Korea
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Wonkwang University Hospital
Gastric Cancer, Gastric Ulcer
HFNO Combined With NPA Reduces Hypoxia During Sedated Gastrointestinal Endoscopy In Obese Patients
Obesity is associated with adverse airway events including desaturation during deep sedation. Previous studies have suggested that high-flow nasal oxygenation may be superior to regular (low-flow) nasal cannula for prevention of…
- Conditions
- Gastric Cancer, Gastric Ulcer, Intestinal Cancer, Intestinal Polyps
- Trial name
- NCT05526339
- Testing
- High-flow nasal oxygenation combined with nasopharyngeal airway, Regular nasal cannula combined with nasopharyngeal airway
- Where
- 2 sites in China
- Volunteers
- 600 people
- Sponsor
- RenJi Hospital
Hypoxemia During Surgery, Gastrointestinal Endoscopy
Respiratory Safety of Oliceridine During Sedated Gastrointestinal Endoscopy
This study is a prospective, single-center, double-blind, randomized controlled trial designed to evaluate the effect of oliceridine versus sufentanil on the incidence of hypoxemia in adult patients undergoing gastrointestinal…
- Trial name
- NCT07187765
- Testing
- Oliceridine, Sufentanil
- Where
- China
- Volunteers
- 508 people
- Sponsor
- Shiyou Wei
Lacertaions
A Clinical Trial of Oral Midazolam Plus Oral Ketamine for Sedation During Laceration Repair
Background: Sedation is often needed for young children undergoing minor procedures in the emergency department (ED). Oral midazolam is one of the most commonly used regimens for children undergoing laceration repair but its…
- Trial name
- NCT01470157
- Testing
- Ketamine, Normal Saline
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Assaf-Harofeh Medical Center
Pain, Anxiety
Effect of Music Over the Tolerance to Colonoscopy.
This study will evaluate the efficacy of music (a very well selected list of songs)on improving the tolerance to the colonoscopy. The patients will be randomly assigned to receive music or not.
- Trial name
- EMOC (NCT01285284)
- Testing
- Music, No music
- Where
- 4 sites in Chile
- Volunteers
- 300 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Minimally Sedated Patient Undergoing Colonoscopy
Comparing Maximal and Half-maximal Suction Pressure Applied During Water Exchange in Colonoscopy
This prospective, randomize, controlled trial will compared maximal to half-maximal suction pressure applied during water exchange in patients undergoing minimally sedated colonoscopy.
- Trial name
- NCT01948284
- Testing
- half-maximal pressure, maximal pressure, Suction Unit
- Where
- Taiwan
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Dalin Tzu Chi General Hospital
Pain Threshold, Conscious Sedation
Correlation Between Pain Threshold and Analgesic Consumption in Transvaginal Oocyte Aspiration Patients
Nowadays, in vitro fertilization (IVF) is an important component of modern infertility treatment. One of the critical stages of the IVF process is oocyte (egg) retrieval, which requires both anesthesia and analgesia; this…
- Conditions
- Pain Threshold, Conscious Sedation, Oocyte Retrieval
- Trial name
- NCT07262216
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Burcu ayvazoğlu