Clinical trials: Sedation During
Monitoring Noxious Events Using EEG-Derived Pain Indices, Procedural Sedation and Analgesia
qNOX Response to Nociceptive Motor Events During Procedural Sedation
The goal of this observational study is to evaluate whether the CONOX monitor can detect pain during sedation in patients undergoing urological procedures.
- Conditions
- Monitoring Noxious Events Using EEG-Derived Pain Indices, Procedural Sedation and Analgesia, Monitored Anesthesia Care
- Trial name
- MO-NOX (NCT07413848)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ankara University
Failed Moderate Sedation During Procedure
A Comparison of the Sedation During Endoscopy in Children
The primary aim of this study was to investigate the efficiency and safety of midazolam plus ketamine versus fentanyl plus propofol administered to children undergoing UGE and to determine the most appropriate sedation protocol.
- Trial name
- NCT02732132
- Testing
- Ketamine and Midazolam, Propofol and Fentanyl
- Volunteers
- 238 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Pain, Anxiety
Pediatric Laser Acupuncture and Renal Biopsy
The purpose of this study is to test if treatment with laser therapy in pediatric patients undergoing renal biopsies will improve patient satisfaction of the overall procedure.
- Trial name
- NCT01879826
- Testing
- Aculaser applied to kidney points
- Where
- 2 sites in United States
- Volunteers
- 81 people
- Sponsor
- University of California, San Francisco
Laryngectomy; Status
Effect of Dexmedetomidine in Preventing Cough and Postoperative Pain After Laryngeal Surgery for Cancer
Background: During emergence from anesthesia for partial and total laryngectomy, severe airway reflex and systemic hypertension during recovery may lead to pneumoderm, hemorrhage, pneumomediastinum or pneumothorax.
- Trial name
- NCT03918889
- Testing
- Dexmedetomidine Injectable Product, Midazolam injection
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Noninvasive Ventilation, Respiratory Insufficiency
The Effect of High-flow Nasal Oxygenation to the Saturation During Analgo-sedation in Different ASA Risk Class Patients
Analgo-sedation is standard procedure in anesthesiology practice and is often given for colonoscopy in the setting of daily hospital.
- Conditions
- Noninvasive Ventilation, Respiratory Insufficiency, Deep Sedation, Hypoxia
- Trial name
- NCT03687385
- Testing
- high-flow nasal oxygenation (HFNO), low-flow nasal oxygenation (LFNO)
- Volunteers
- 126 people
- Sponsor
- Anita Vukovic
Pain, Colorectal Adenomas
A Comparison of Air Insufflation, Water Immersion and Water Exchange Colonoscopy in Diagnostic Patients
Water-aided method for colonoscopy can be broadly subdivided into two major categories. Water Immersion (WI), characterized by suction removal of the infused water predominantly during the withdrawal phase of colonoscopy, and…
- Conditions
- Pain, Colorectal Adenomas, Colorectal Cancer
- Trial name
- NCT01781650
- Testing
- Air Insufflation method., Water Immersion method., Water Exchange method.
- Where
- 3 sites in United States, Italy
- Volunteers
- 288 people
- Sponsor
- Presidio Ospedaliero Santa Barbara
Pain
SNAP VS BIS(OAA/S) Scale During a Sedation Regimen With and Without Ketamine
The study question: Does the SNAP-Index (SI) correlates better with the OASS than the BIS Monitor during sedation with ketamine? The study hypothesis: Since the SNAP II monitor seems to be more responsive during emergence of…
- Trial name
- NCT01250418
- Testing
- Ketamine group
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Northwestern University
Airway Obstruction, Sedation Complication
Medical Device for Airway Patency During Sedation
OVERALL SYNOPSIS PART A: Systematic evaluation in spontaneously breathing healthy volunteer study participants of cumulative duration of manual measures for airway patency and for mask ventilation with airway device prototype…
- Conditions
- Airway Obstruction, Sedation Complication, Perioperative Complication
- Trial name
- STAIRWAY-2 (NCT06270212)
- Testing
- STAIRWAY, NO DEVICE
- Where
- Sweden
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Stairway Medical AB
Seeing the Benefits of Using 4 Channel EEG During the DISE Procedure With Sedation
Evaluation of Anesthesia Depth Using 4-channel EEG in Patients Undergoing Drug-induced Sleep Endoscopy (DISE) With Two Different Sedation Methods.
You will undergo a drug-induced sleep endoscopy procedure. The drugs we use to create routine sedation will be used as medication.
- Trial name
- NCT06511128
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ankara City Hospital Bilkent
Carbon Dioxide Insufflation During Colonoscopy
Efficacy and Safety of Carbon Dioxide Insufflation During Endoscopy
The purpose of this study is to assess the differences of safety and efficacy of carbon dioxide insufflation instead of air during sedated or unsedated endoscopy.
- Trial name
- NCT02502136
- Testing
- carbon dioxide insufflation during endoscopy
- Volunteers
- 640 people
- Sponsor
- Chang Gung Memorial Hospital
Chronic Pain
Sedation in Endoscopic Retrograde Cholangiopancreatography (ERCP) With or Without Opioids
Addition of fentanyl or remifentanil to the propofol produced sedation for scheduled ERCP will decrease the propofol requirements for predetermined sedation levels (as shown by Bispectral Index Monitor (BIS) monitor), will be…
- Trial name
- NCT01304342
- Testing
- Remifentanil, Fentanyl, Normal saline
- Where
- Greece
- Volunteers
- 180 people
- Sponsor
- University of Athens
Sedation During
Composite Variability Index Versus Bispectral Index (BIS)
The aim of this study is to compare the accuracy of the changes in CVI in response to a standardized noxious stimulus during various targeted pseudo-steady-state concentrations of remifentanil and various steady state level of…
- Trial name
- NCT01053611
- Testing
- propofol + remifentanil 0 ng/ml, propofol + remifentanil 2 ng/ml, propofol + remifentanil 4 ng/ml
- Where
- Netherlands
- Volunteers
- 140 people
- Sponsor
- University Medical Center Groningen
Endoscopic Ultrasound
Comparison of Oxygenation Between Nasal PAP vs Nasal During Propofol-based Sedation for EUS
Randomized controlled single site study involves oxygenation, continuous positive airway pressure, and ventilation of subject via nasal mask and oxygenationvia closed facemask.
- Trial name
- SuperNo2VA (NCT04306211)
- Testing
- SuperNO2VA
- Where
- 2 sites in United States
- Volunteers
- 11 people
- Sponsor
- Indiana University
Macular Holes, Intraocular Lens Opacification
Oral Sedation in Vitreoretinal Surgery
The purpose of this study is to compare the efficacy of oral sedation to intravenous sedation with anesthesiology support and monitoring.
- Conditions
- Macular Holes, Intraocular Lens Opacification, Vitrectomy, Vitreous Hemorrhage
- Trial name
- NCT04346095
- Testing
- Oral Sedatives with or Without Analgesia, Intravenous Sedatives with or Without Analgesia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Rocky Vista University, LLC
Conscious Sedation Failure During Procedure
Non-anesthesiologist-administered Propofol During the Flexible Bronchoscopy
Flexible bronchoscopy (FB) is a fundamental procedure for the diagnosis and treatment of respiratory diseases. Although midazolam is the recommended sedative agent by most guidelines, propofol has gained popularity due a short…
- Trial name
- NCT02820051
- Testing
- Transcutaneous CO2 monitor, Midazolam, Propofol
- Where
- Mexico
- Volunteers
- 102 people
- Sponsor
- Hospital Universitario Dr. Jose E. Gonzalez
Desaturation, Hypoxemia
Prevention of Desaturations Using Positive Airway Pressure or Capnometry During ERCP
Although sedation during endoscopy is sufficiently safe, desaturations are among the most common side effects of endoscopic retrograde cholangiopancreatography (ERCP) procedures, occurring in approximately 20-30% of cases.
- Conditions
- Desaturation, Hypoxemia, ERCP
- Trial name
- PrePAP-ERCP (NCT07056075)
- Testing
- Nasal PAP Ventilation System, Low Flow Oxygen, Capnometry
- Where
- 2 sites in Austria
- Volunteers
- 288 people
- Sponsor
- Karl Landsteiner University of Health Sciences
Colonoscopy
Comparing Warm Versus Cool Temperature Water During Colonoscopy
The purpose of this study will be to determine if the temperature of water used during insertion of colonoscopy makes a difference in patient discomfort and sedation requirements.
- Trial name
- NCT01322724
- Testing
- Warm vs Cool water
- Where
- United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- OHSU Knight Cancer Institute
Pain, Patient Satisfaction
Patient-controlled Sedation During Repair of Obstetric Perineal Lacerations
The PROP(ofol)-study (EU CT number: 2022-502292-39-00, protocol number: ) is a clinical trial phase IV single centre prospective randomized controlled trial with parallel groups.
- Trial name
- NCT06044103
- Testing
- PDB + PCS
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Marie Blomberg
Virtual Reality, Anxiety
Pain Procedures and Anxiolysis Via Distraction With Virtual Reality
The purpose of this study is to evaluate the efficacy of VR distraction on reducing anxiety patients undergoing interventional pain procedures compared to placebo/active placebo or a non VR option.
- Conditions
- Virtual Reality, Anxiety, Pain
- Trial name
- PAIN-VR (NCT04437173)
- Testing
- Virtual Reality Headset Distraction
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- University of California, Davis
Coronary Angioplasty
Effect of Music on the Sedative Use During Coronary Angioplasty
This is a non-blinded, non-randomized controlled pilot study with no follow-up. Patients will be recruited from the coronary angiography patient pool of the American Hospital of Paris and assigned to one of 2 groups in a…
- Trial name
- NCT03817775
- Testing
- Music therapy
- Where
- France
- Volunteers
- 76 people
- Sponsor
- Association de Musicothérapie Applications et Recherches Cliniques