Clinical trials: Sedation During
Pain, Anxiety
Estimation of Analgetic Effect and Cooperability of Pediatric Patients During Application of Gass Mixture of Oxygen:Nitrogen Suboxide 50%:50% for Minimal Invasive Procedures
The goal of this observational study is to observe analgetic and anxiolytic effect of gass mixture of oxygen:nitrigen suboxide 50%:50% in pediatric patients sujected to minimal invasive procedures.
- Conditions
- Pain, Anxiety, Sedation
- Trial name
- NCT07159425
- Where
- Serbia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mother and Child Health Institute of Serbia Dr Vukan Cupic
Propofol, Anesthesia
Investigating Near-Threshold Perception During Anesthetic Sedation
The researchers expect to gain a deeper understanding of mental function during different levels of anesthesia. Propofol is FDA approved for use in patients undergoing an anesthetic for medical treatment but is not approved for…
- Conditions
- Propofol, Anesthesia, fMRI
- Trial name
- NCT06403852
- Testing
- Functional Magnetic Resonance Imaging (fMRI) with propofol
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Juvenile Idiopathic Arthritis, Joint Inflammation
Intranasal Dexmedetomidine Sedation During Intra-articular Joint Injections in Pediatric Population
The main objective of this study is to evaluate the effectivity of intranasal dexmedetomidine sedation during intra-articular injection therapy.
- Trial name
- NCT03069638
- Testing
- Dexmedetomidine, Sedatives/Hypnotics,Other
- Where
- Finland
- Volunteers
- 68 people
- Sponsor
- University of Oulu
Surgery With General Anesthesia
Validation of the Effect of Propofol and Opiates Closed-loop Administration Device During Anesthesia and Sedation
Sleeping medication and analgesia are standard administered during anesthesia. Sleeping medication, Propofol (Diprivan, AstraZeneca), and analgesia, Remifentanil (GlaxoSmithKline), are most frequently used In the University…
- Trial name
- NCT00764855
- Testing
- Automatic administration of propofol and opiates during routine clinical practice
- Where
- Belgium
- Volunteers
- 180 people
- Sponsor
- University Hospital, Ghent
Sedation
Assessment of Sedation During Endoscopy
Use of sedation is often required in endoscopic procedures such as ERCP (endoscopic retrograde cholangiopancreatography). However, assessment of the level of sedation during these procedures is not investigated in detail.
- Trial name
- NCT01747733
- Testing
- Bispectral Index
- Where
- Finland
- Volunteers
- 200 people
- Sponsor
- Helsinki University Central Hospital
Procedural Anxiety
Virtual Reality as a Substitute to Pharmacological Sedation During PICC Placement in Pediatric Patients
In pediatric patients Peripherally Inserted Central Catheters (PICC) insertion requires pharmacological sedation provided by an anesthesiologist, which poses a certain degree of risks.
- Trial name
- ViVA (NCT05275621)
- Testing
- Virtual Reality, PICC positioning
- Where
- 6 sites in Italy
- Volunteers
- 120 people
- Sponsor
- ASST Fatebenefratelli Sacco
Outpatient Colonoscopy for Colorectal Cancer Screening or for Symptoms Suggestive of Colonic Diseases
Effect of Anesthesia on Force Application During Colonoscopy
The aim of the study is to determine if more force is used during colonoscopy when patients receive monitored anesthesia with propofol versus conscious sedation.
- Trial name
- CFM (NCT02101099)
- Testing
- Colonoscopy Force Monitor
- Where
- 3 sites in United States
- Volunteers
- 102 people
- Sponsor
- Artann Laboratories
Hypoxemia During Surgery
Prediction Model of Hypoxemia in Gastrointestinal Endoscopy Sedation
The incidence of hypoxemia during gastrointestinal endoscopy sedation is high, but there is still a lack of perfect prediction model of hypoxemia, which often leads to unpredictable respiratory complications.
- Trial name
- NCT06016998
- Where
- China
- Volunteers
- 1,023 people, healthy volunteers welcome
- Sponsor
- Sichuan Provincial People's Hospital
Anesthesia
Airway Nerve Block Versus Nebulization by Lignocaine During Diagnostic Flexible Bronchoscopy Under Moderate Sedation.
To compare the effectiveness of nebulization versus airway nerve block technique to achieve upper airway anesthesia for diagnostic fiberoptic bronchoscopy under moderate sedation.
- Trial name
- NCT04806438
- Testing
- Group A, Group B
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Multiparametric Magnetic Resonance Imaging, Propofol Adverse Reaction
Safety Evaluation of Propofol Sedation for Magnetic Resonance Imaging in Pediatric Patients
Propofol is often used for sedation in children undergoing magnetic resonance imaging. The investigators will perform a chart review of 4 month of activity (about 100 cases) and review the incidence and severity of adverse events…
- Conditions
- Multiparametric Magnetic Resonance Imaging, Propofol Adverse Reaction, Sedation Complication, Anesthesia; Adverse Effect
- Trial name
- NCT04455776
- Testing
- Propofol
- Where
- Belgium
- Volunteers
- 99 people
- Sponsor
- Brugmann University Hospital
Anesthesia, Sedation
Sedation During Endoscopy Using Remimazolam: Efficacy in a Novel Exploration
This study is a pragmatic, randomized controlled pilot trial comparing remimazolam with propofol for endoscopic procedures, designed to assess the feasibility and clinical outcomes associated with implementing a pragmatic…
- Conditions
- Anesthesia, Sedation, Endoscopy
- Trial name
- SERENE (NCT07269808)
- Testing
- Remimazolam, Propofol
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Gastroscopy, Colonoscopy
A Clinical Trial to Evaluate the Efficacy and Safety of Methoxyethyl Etomidate Hydrochloride for Sedation/Anesthesia During Gastroscopy/Colonoscopy
A total of 270 subjects undergoing gastroscopy/colonoscopy were randomly assigned to the methoxetomidate hydrochloride group and the etomidate group according to the ratio of 2:1 with etomidate as the control group.Neither the…
- Trial name
- NCT06858852
- Testing
- ET-26HCl 0.8mg/kg group, Etomidate Injectable Product 0.3mg/kg group
- Where
- 6 sites in China
- Volunteers
- 270 people
- Sponsor
- Ahon Pharmaceutical Co., Ltd.
Cardiac Output, Sedation
Assess the Ability of Electrical Cardiometry to Trend Hemodynamic Variables During Dexmedetomidine Sedation
The aim of the study is to investigate the use of a new FDA-approved non-invasive bio-impedance cardiac monitor, ICON, to detect hemodynamic effects during sedation in children undergoing radiology procedures.
- Trial name
- DEX-CO (NCT01001533)
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Boston Children's Hospital
Oocyte Retrieval, Sedation, Conscious
Respiratory Depression During an Analgosedation Combining Remifentanil and Ketamine in TCI for Oocyte Retrieval
This study evaluates the effect of the addition of ketamine to a conscious sedation protocol including remifentanil during oocyte retrieval.
- Conditions
- Oocyte Retrieval, Sedation, Conscious, Ventilatory Depression
- Trial name
- NCT03458143
- Testing
- Ketamine 150 ng/ml, Remifentanil, Oocyte retrieval
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Erasme University Hospital
Biliary Colic
Sedation for Patients Undergoing Endoscopic Retrograde Cholangiopancreatography
This study was performed to evaluate the role of BIS monitored sedation in reducing the dose of propofol and to know the effectiveness of pre-procedure administration of intravenous diclofenac sodium along with topical pharyngeal…
- Trial name
- NCT04860167
- Testing
- Propofol, Diclofenac Sodium and Lignocaine 10 % spray
- Where
- India
- Volunteers
- 90 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Deep Sedation
Dexmedetomidine Sedation in Children Before MRI Examinations
Dexmedetomidine, has been used in the past 4-5 years as an alternative sedation method for children at the pediatric radiology department in order to reduce the waiting lists and the use of general anesthesia with its risks and…
- Trial name
- NCT05163704
- Testing
- Dexmedetomidine
- Where
- Sweden
- Volunteers
- 1,091 people
- Sponsor
- Karolinska University Hospital
Tracheal Intubation, Rapid Sequence Induction and Intubation
Sequential Order of RSI on Tracheal Intubation
This clinical trial aims to understand the effect of the order of administration of Neuromuscular Blocking Agents (NMBAs) and sedatives on the success rate of intubation during Rapid Sequence Intubation (RSI) in the emergency…
- Trial name
- NCT07741578
- Testing
- Drug Sequence
- Where
- China
- Volunteers
- 380 people
- Sponsor
- Zhongnan Hospital
Complex Partial Seizures
Intra Cranial EEG Activity During Dexmedetomidine Sedation
Various parts of the brain are sensitive to various anesthetics.We like to study the effect of dexmedetomidine on the different parts of the brain in patients who are coming for DBS electrode removal under sedation.
- Trial name
- NCT01648959
- Testing
- EEG Recording
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- University Health Network, Toronto
Cannabis Use, Marijuana Usage
Impact of Cannabis Use During Third Molar Surgery
This study is for people scheduled to have their wisdom teeth (third molars) removed and are going to receive drug through an IV to put them to sleep.
- Conditions
- Cannabis Use, Marijuana Usage, Sedation and Analgesia, Wisdom Tooth
- Trial name
- NCT07423195
- Where
- United States
- Volunteers
- 242 people
- Sponsor
- University of Michigan
Sedation Complication, Sedation During GI Endoscopy
Safety of Sedation During Interventional Endoscopy
Sedation is routinely used during interventional endoscopic procedures to improve patient comfort and optimize procedural conditions.
- Trial name
- SCOPE-SAFE (NCT07872657)
- Testing
- Sedation during interventional endoscopy
- Where
- Austria
- Volunteers
- 500 people
- Sponsor
- Medical University Innsbruck