Clinical trials: Sedation in ERCP
Gastrointestinal Endoscope, Endoscopic Retrograde Cholangiopancreatogram (ERCP)
Electronic Respiratory Sound Monitoring System in Gastrointestinal Endoscopic Sedation
This study aims to evaluate the application of an electronic respiratory sound monitoring system during sedation for gastrointestinal endoscopy and to determine its effectiveness in improving sedation quality.
- Trial name
- NCT06938919
- Testing
- routine care without electronic respiratory sound monitoring system, routine care with electronic respiratory sound monitoring system
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Sedation, Hypoxia
Doxapram as an Additive to Propofol Sedation in Sedation for ERCP
Sedation is needed in order to complete endoscopic retrograde cholangiopancreatography (ERCP) to alleviate discomfort and pain during the procedure.
- Trial name
- NCT02171910
- Testing
- Doxapram
- Where
- Finland
- Volunteers
- 50 people
- Sponsor
- Helsinki University Central Hospital
Dexmedetomidine Induced Sedation, Nasal Administration
Efficacy Study of Dexmedetomidine Nasal Spray Combined With Propofol for Deep Sedation in ERCP
This prospective randomized single-blind study evaluated the safety and efficacy of combining dexmedetomidine nasal spray with propofol for ERCP (Endoscopic Retrograde Cholangiopancreatography) sedation in eligible patients aged…
- Conditions
- Dexmedetomidine Induced Sedation, Nasal Administration, Sprays
- Trial name
- NCT07204106
- Testing
- Dexmedetomidine Injection (nasal spray) + Propofol Injection + Sufentanil Injection, Normal Saline (nasal spray) + Dexmedetomidine Injection (intravenous) + Propofol Injection + Sufentanil Injection, Regular sedation protocol
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Shiyou Wei
Biliary Tract Diseases, Procedural Sedation and Analgesia
Esketamine Versus Sufentanil for Sedation in Patients Undergoing ERCP
This study compares two anesthesia medications, esketamine and sufentanil, used together with propofol during ERCP procedures. The goal is to find out which combination provides better safety and comfort for people undergoing…
- Trial name
- ES-ERCP (NCT07702240)
- Testing
- Esketamine, Sufentanil
- Volunteers
- 530 people
- Sponsor
- Ren Da
Satisfaction, Complication
CO2 Versus O2 Insufflation During ERCP Depending on Sedation Protocols
Endoscopic retrograde cholangiopancreatography(ERCP) and related procedures can cause abdominal pain and discomfort. Some clinical trials have indicated, using the visual analogue scale (VAS) score, that CO2 insufflation during…
- Trial name
- NCT01761474
- Where
- South Korea
- Volunteers
- 210 people
- Sponsor
- Soon Chun Hyang University
Sedation
Lidocaine Infusion for Propofol Dose Reduction in ERCP Procedure
This study aims to investigate the dose reduction of propofol if associated with continuous infusion of lidocaine during ERCP procedures in patients over 65 years old.
- Trial name
- NCT05274984
- Testing
- Lidocaine
- Where
- Romania
- Volunteers
- 100 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Conscious Sedation
Gabapentin to Improve Patient Tolerance in Endoscopic Retrograde Cholangiopancreatography (ERCP)
The standard approach to sedation in endoscopic retrograde cholangiopancreatography (ERCP) involves the use of benzodiazepines and opiates to achieve a moderate depth of sedation.
- Trial name
- NCT01143766
- Testing
- Gabapentin, Standard sedation regimen
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Indiana University
Sedation
Target-controlled Infusion Versus Patient-controlled Sedation With Propofol in Endoscopic Retrograde Cholangiopancreatography (ERCP)
Propofol is a drug of choice for deep sedation in endoscopy. Propofol can be administered in many ways: by infusion or intravenous boluses and with self-administration device (patient-controlled sedation; PCS).
- Trial name
- NCT01072435
- Testing
- Patient-controlled sedation, Target-controlled infusion
- Where
- Finland
- Volunteers
- 82 people
- Sponsor
- Helsinki University Central Hospital
Anesthesia, Sedation
EEG-Guided Sedation in ERCP Procedures
Patients undergoing ERCP have a wide range from patients with poor general condition and septicaemia findings to outpatients who come as day patients without any other additional disease.
- Conditions
- Anesthesia, Sedation, Sedation Complication, Anesthesia, Intravenous
- Trial name
- ERCP-EEG (NCT06866886)
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Ankara City Hospital Bilkent
Sedation in ERCP
Propofol Versus Dexmedetomidine for Sedation of Cancer Patients Undergoing ERCP
The aim of this study is to compare the efficacy and safety of propofol and dexmedetomidine during ERCP regarding hemodynamic, respiratory, sedative and cognitive functions.
- Trial name
- NCT06409104
- Testing
- Propofol, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 202 people
- Sponsor
- National Cancer Institute, Egypt
Biliary Tract Diseases, Pancreatic Diseases
Alfentanil Versus Remifentanil in Patient-controlled Sedation During Endoscopic Retrograde Cholangiopancreatography (ERCP)
Self-administration of propofol and opioid mixture by the patient him- or herself (patient-controlled sedation, PCS) could be successful alternative to the anesthesiologists-managed deep sedation during endoscopic retrograde…
- Trial name
- NCT01350037
- Testing
- alfentanil, remifentanil
- Where
- Finland
- Volunteers
- 81 people
- Sponsor
- Helsinki University Central Hospital
Sedation, Endoscopy
Opioid-Free Versus Opioid-Based Sedation for Endoscopic Procedures
This study will compare two different sedation approaches used during gastroscopy, colonoscopy, and endoscopic retrograde cholangiopancreatography (ERCP).
- Conditions
- Sedation, Endoscopy, Colonoscopy, Endoscopic Retrograde Cholangiopancreatography (ERCP)
- Trial name
- NCT07649746
- Testing
- Dexmedetomidine, Remifentanil
- Volunteers
- 80 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Hypoxemia, Hemodynamic Instability
High-Flow Nasal Oxygen During Endoscopic Retrograde Cholangiopancreatography In Geriatric Patients
This prospective, single-centre, randomized controlled trial evaluates whether high-flow nasal oxygen (HFNO) reduces hypoxaemia compared with conventional low-flow oxygen therapy (COT) during endoscopic retrograde…
- Trial name
- HFNO ERCP (NCT07493811)
- Testing
- HFNO, Conventional Oxygen Therapy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Conscious Sedation Failure During Procedure
Balanced Propofol Sedation Versus Propofol Alone Sedation in Therapeutic Endoscopic Retrograde Cholangiopancreatography (ERCP)
Based on previous results, the investigators considered that sedation quality, complications, and procedure outcomes may not be different, however, propofol alone titration may have a fast recovery time than BPS and…
- Trial name
- ERCP (NCT01321047)
- Testing
- Propofol, BPS
- Volunteers
- 204 people
- Sponsor
- Soon Chun Hyang University
Obese
HFNO Versus Nasal CPAP in Obese Patients Undergoing Deep Sedation for ERCP
Endoscopic retrograde cholangio-pancreatography (ERCP) is commonly performed under deep sedation to provide amnesia, comfort, and optimal procedural conditions.
- Trial name
- NCT04912102
- Testing
- high flow nasal oxygen device (HFNO)
- Volunteers
- 270 people
- Sponsor
- Assiut University
Biliary and Pancreatic Diseases, Endoscopic Retrograde Cholangiopancreatography (ERCP)
Effect of Deep Analgosedation vs. Endotracheal Intubation General Anesthesia on on Perioperative Sedation Related Adverse Events in Elderly ERCP Patients
This study aims to investigate the impact of deep analgosedation versus endotracheal intubation general anesthesia on perioperative sedation related adverse events in elderly ERCP patients.
- Trial name
- NCT07017283
- Testing
- Tracheal intubation general anesthesia, Nasopharyngeal airway ventilation
- Where
- China
- Volunteers
- 170 people
- Sponsor
- Gang Chen
Sedation
Dexmedetomidine Versus Ketofol for Moderate Sedation in Endoscopic Retrograde Cholangiopancreatography
Patients were randomly divided into Dexmedetomidine or Ketofol for sedation. In patients who received Dexmedetomidine, a 2ml ampule of 100 ug/ml was diluted in 18 ml of normal saline, making a total volume of 20 ml.
- Trial name
- NCT06212401
- Testing
- Dexmedetomidine, Ketofole
- Where
- Pakistan
- Volunteers
- 62 people
- Sponsor
- Sindh Institute of Urology and Transplantation
Cholangitis, Pancreatic Cancer
Ketamine-midazolam as a Sedative Agent in Endoscopic Retrograde Cholangiopancreatography.
Does Ketamine-Midazolam have a better efficacy and safety profile compared to Midazolam - Pethidine in Endoscopic Retrograde Cholangiopancreatography (ERCP)?
- Conditions
- Cholangitis, Pancreatic Cancer, Choledocholithiasis, Choledochal Cyst
- Trial name
- NCT06111872
- Testing
- Ketamine, Midazolam, Pethidin
- Where
- Malaysia
- Volunteers
- 90 people
- Sponsor
- National University of Malaysia
Endoscopy, Gastrointestinal, Procedural Sedation
The Efficacy of Laryngeal Mask Airway Gastro (LMA® Gastro™) in Preventing Hypercarbia in ERCP Patients
Endoscopic retrograde cholangiopancreatography (ERCP) has evolved into a primarily therapeutic procedure that often requires anesthetic support.
- Conditions
- Endoscopy, Gastrointestinal, Procedural Sedation, Anesthesia Airway Management, Anesthesia for Endoscopic Procedures
- Trial name
- NCT07182786
- Testing
- LMA Gastro
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Anesthesia, Sedation
Efficacy and Safety of Anricofen Combined With Ciprofol for Deep Sedation in Elderly Patients Undergoing ERCP
Background: Endoscopic retrograde cholangiopancreatography (ERCP) is a key technique for treating pancreatobiliary diseases in the elderly.
- Conditions
- Anesthesia, Sedation, ERCP, Ciprofol
- Trial name
- Anricofen Cipr (NCT07376577)
- Testing
- Sufentanil, Anricofen, Ciprofol
- Where
- China
- Volunteers
- 141 people
- Sponsor
- The First Affiliated Hospital of Xinxiang Medical College