Clinical trials: Sedentary Subjects
Physical Exertion
Acute Exercise and Microvascular Function
It is well recognized that chronic exercise protects against the development of cardiovascular diseases. However, the responses of vasculature to acute exercise (AE) are not well known and not consistent in literature.
- Trial name
- NCT02727439
- Testing
- Acute Exhausting Exercise (AE)
- Where
- Croatia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Josip Juraj Strossmayer University of Osijek
Influenza
Randomized, Double Blinded, Placebo Control Clinical Trial of Pandemic Influenza Inactive Vaccine on Healthy Subjects
Based on pre-clinical trial data and principle of GCP, the objective of phase I clinical trial is to evaluate safety and immunogenicity of Pan-flu vaccine, an inactivated whole virion H5N1 vaccine with aluminium hydroxide…
- Trial name
- NCT00356798
- Testing
- an inactivated whole virion H5N1 vaccine, adjuvanted
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sinovac Biotech Co., Ltd
Type 2 Diabetes
Marathon Runners Compared to Sedentary Matched Control Subjects
The investigators wish to compare very active runners in healthy untrained control subjects on a number of parameters. The project aims to understand the underlying mechanisms by which physical inactivity causes diseases.
- Trial name
- NCT02001805
- Where
- Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Inge Holm
Urinary Incontinence (UI), Urinary Incontinence , Stress
Difference in Incontinence Prevalence Between High Impact Athletes, Low Impact Athletes and Sedentary Subjects
This observational cross-sectional study aims to investigate the association between participation in high-impact sports, physical activity level, and urinary incontinence in young adults.
- Trial name
- NCT07710508
- Testing
- No Intervention: Observational Cohort
- Where
- Spain
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Thyroid Eye Disease
A Clinical Study to Evaluate the Efficacy and Safety of IBI311 in Subjects With Inactive Thyroid Eye Disease
A multicenter clinical study to evaluate the efficacy and safety of IBI311 in subjects with inactive thyroid eye disease. The study consists of two parts, with a maximum duration of approximately 64 weeks.
- Trial name
- NCT07113262
- Testing
- IBI311
- Where
- China
- Volunteers
- 111 people
- Sponsor
- Innovent Biologics (Suzhou) Co. Ltd.
Vascular Disease, Peripheral, Physical Inactivity
Inter-individual Physiological Response to a Training and Detraining Period in Cardiometabolic Risk Factors Subjects
Background: Although exercise training is a well described therapy for some cardiometabolic diseases such as obesity, type 2 diabetes, arterial hypertension, and metabolic syndrome, there is scarcity of knowledge about the…
- Conditions
- Vascular Disease, Peripheral, Physical Inactivity, Arterial Hypertension, Endothelial Dysfunction
- Trial name
- VASCU-HEALTH (NCT05710653)
- Testing
- Exercise training intervention
- Where
- Chile
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Cristian Alvarez
Cognition
A Study to Compare Two Medications With an Inactive Medication and Look at the Effect on a Person's Mental Ability
The purpose is to compare solifenacin and oxybutynin with an inactive tablet and assess any potential effects on mental ability.
- Trial name
- SENIOR (NCT01126424)
- Testing
- Solifenacin, Oxybutynin
- Where
- 3 sites in United Kingdom
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
Muscle Function, Mitochondrial Function, Overweight
AMAZ-02 Effect on Exercise ToLerance in Healthy, Overweight Middle Aged Subjects (ATLAS Trial)
This is a Phase 2 randomized, double-blind, placebo-controlled study enrolling 90 healthy, overweight, middle aged subjects (30 placebo, 30 low dose and 30 high dose AMAZ-02 intervention), 40-65 years of age, who are otherwise…
- Conditions
- Muscle Function, Mitochondrial Function, Overweight, Healthy Aging
- Trial name
- ATLAS (NCT03464500)
- Testing
- Mitopure 500mg, Mitopure 1000mg
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Sedentary Subjects
Effects of Training in Healthy Sedentary Subjects
The purpose of this study is to understand underlying mechanisms of improved exercise tolerance in Healthy Sedentary Subjects after training program.
- Trial name
- NCT01183039
- Testing
- Training
- Where
- 3 sites in France
- Volunteers
- 30 people
- Sponsor
- 5 Santé
SCI - Spinal Cord Injury, Cardiovascular Risk Factor
Cardiovascular Risk Markers in Spinal Cord Injured Subjects of the Wheelchair Dancer Study
The present study will analyze if exercise is able to elicit the well-known anti-atherogenic effects in patients with SCI. This will be evaluated by measuring vascular parameters such as endothelial and inflammatory blood…
- Trial name
- NCT03352505
- Where
- 2 sites in Austria
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Paracelsus Medical University
Stroke, Chronic Stroke Patients
Development and Validation of an Actimetric Protocol to Quantify Physical Activity and Sedentary Behaviour in Post-stroke Subjects
The aim of this project is to develop an actimetry protocol based on a system of motion sensors, such as accelerometers and pressure insoles.
- Conditions
- Stroke, Chronic Stroke Patients, Stroke With Hemiparesis
- Trial name
- ActiStroke (NCT06943014)
- Testing
- Actimetry Protocol
- Where
- Belgium
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Sedentary Behavior
Sprint Interval Training on the Endurance, Strength and Velocity Capacities of Healthy Sedentary Subjects
The present study aims to analyse first, the acute effects generated by a single bout of Sprint Interval Training (SIT) and, secondly, the effects of a long-term intervention on sedentary participants.
- Trial name
- BénéfiSIT (NCT05013021)
- Testing
- Sprint Interval Training
- Where
- France
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Sedentary Subjects
Polyphenols and Endothelial Function
To determine whether fruit juice rich in polyphenols might increase exercise capacity and memory in healthy sedentary subjects.Both parameters might be improved because of the anti-oxidant effects of polyphenols.
- Trial name
- NCT00619749
- Testing
- juice rich in polyphenols, juice poor in polyphenols
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Athlete Heart
Interaction Between Intraventricular Flow and Cardiac Mechanics Using 3D Echocardiography in Athletes and Sedentary Subjects
Exercise-induced cardiac remodeling, known as the "athlete's heart," corresponds to morphological and functional adaptations of the left ventricle in response to prolonged physical training.
- Trial name
- CARDIO-3D (NCT07363993)
- Where
- 2 sites in France
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Avignon
Thyroid Eye Disease
A Study of IBI311 in Subjects With Inactive or Active Thyroid Eye Disease
This is a multicenter, randomized, double-masked phase II study evaluating the efficacy and safety of IBI311 in subjects with inactive or active thyroid eye disease.
- Trial name
- NCT06525506
- Testing
- IBI311 (20 mg), IBI311 (3-20 mg), IBI311 (10 mg)
- Where
- China
- Volunteers
- 38 people
- Sponsor
- Innovent Biologics (Suzhou) Co. Ltd.
Analgesia
Hypoalgesic Effects of Walking and Running Imagined
The main objective is to identify the hypoalgesic effect of the imagination of actions in sedentary subjects with high levels of physical activity.
- Trial name
- NCT04548323
- Testing
- Motor imagery
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Madrid
Stroke
Effects of Aerobic Training Post-stroke
Physical activity level is an important determinant of quality of life in persons post-stroke. There is a lack of knowledge regarding the effects of aerobic training on physical activity levels in subjects post-stroke.
- Trial name
- NCT02798237
- Testing
- Aerobic treadmill training, Control (overground walking)
- Where
- Brazil
- Volunteers
- 22 people
- Sponsor
- Federal University of Minas Gerais
Nonfamilial Hypercholesterolemia, Physical Inactivity
Exercise And Rosuvastatin Treatment: Is There an Anti-Inflammatory Synergy?
The purpose of this study is to determine whether the effects of rosuvastatin treatment and exercise training can be synergistic, with respect to the innate immune receptor TLR4, markers of systemic inflammation, and stimulated…
- Trial name
- NCT00295373
- Testing
- Rosuvastatin, Exercise Training
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Purdue University
Age-associated Muscle Loss
AMG 745 in Subjects With Age-associated Muscle Loss
Randomized, Double-blind, Placebo-controlled Dose Ranging Study to Evaluate the Safety and Efficacy of AMG 745 in Age-associated Muscle Loss
- Trial name
- NCT00975104
- Testing
- AMG 745 0.3 mg/kg, AMG 745 1.0 mg/kg, AMG 745 3.0 mg/kg
- Sponsor
- Amgen
Healthy Subjects
Interval Training and Resting Metabolism
It has been reported that obese individuals are seated 2 ½ hour more than lean individuals and that non exercise thermo genesis (NEAT) may vary with as much as 2000 Kcal/day between equal size people due to different occupational…
- Trial name
- NEAT (NCT01313468)
- Testing
- 1 x 4 minute interval, 4 x 4 minutes Intervals, Moderate continuous Training
- Where
- Norway
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology