Clinical trials: Self-Injurious Behavior, open to volunteers
Self-Injurious Behavior, Suicidal Ideation
Therapeutic Evaluative Conditioning to Reduce Adolescents' Self-injurious Thoughts and Behaviors During and After Psychiatric Inpatient Hospitalization
Suicide is the 2nd leading cause of death among adolescents, with the highest risk period for suicide being the month following psychiatric inpatient hospitalization.
- Conditions
- Self-Injurious Behavior, Suicidal Ideation, Suicide Attempts
- Trial name
- TEC (NCT05796531)
- Testing
- Therapeutic Evaluative Conditioning, Neutral comparison condition
- Where
- United States
- Volunteers
- 155 people
- Sponsor
- Franciscan Hospital For Children, INC.
HIV, Suicide
Suicide Assessment and Feasible Evidence-based Treatments for Youth Living With HIV in Lilongwe
The overall aim of this study is to determine the feasibility, fidelity, acceptability, and preliminary effectiveness of the Friendship Bench +Safety Planning intervention in reducing suicidal ideation and behaviors (SIBs) and…
- Trial name
- NCT06770101
- Testing
- Behavioral: Enhanced Friendship Bench + Safety Planning, Augmented usual care
- Where
- 4 sites in Malawi
- Volunteers
- 60 people
- Sponsor
- University of Pennsylvania
Psychotic Disorders, Bipolar Disorders
A Novel Peer-Delivered Recovery-Focused Suicide Prevention Intervention for Veterans With Serious Mental Illness
Suicide is a major public health concern, particularly among Veterans with serious mental illness (SMI, i.e., psychotic disorders or bipolar disorders).
- Conditions
- Psychotic Disorders, Bipolar Disorders, Suicidal Ideation, Suicide, Attempted
- Trial name
- NCT05537376
- Testing
- SUicide Prevention by Peers Offering Recovery Tactics
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- VA Office of Research and Development
Non-suicidal Self-injury (NSSI)
Blended Unified Protocol in Chinese Adolescents With Non-Suicidal Self-Injury
This study utilizes the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Adolescents (UP-A) to address non-suicidal self-injury among Chinese adolescents.
- Trial name
- NCT06858540
- Testing
- Unified protocol for transdiagnostic treatment of emotional disorders in adolescents
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Jian-Jun Ou
Suicidal Ideation
(Cost)-Effectiveness of ABFT for Suicidal Youth.
Young adults who attempt to kill themselves is a common and serious mental health problem worldwide and certainly in Belgium and the Netherlands. Fatal suicide is the leading cause of death among young adults.
- Trial name
- REPAIR (NCT05965622)
- Testing
- Attachment Based Family Therapy (ABFT) + Treatment As Usual (TAU), Treatment As Usual (TAU)
- Where
- 13 sites in Belgium, Netherlands
- Volunteers
- 138 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Major Depressive Disorder (MDD), Suicidal Ideation
Improving Outcomes in Adolescent Inpatient Depression With Deep Transcranial Magnetic Stimulation
Evaluate the feasibility, safety, and preliminary efficacy of deep Transcranial Magnetic Stimulation (dTMS) as an adjunctive treatment for adolescents hospitalized with major depressive disorder (MDD).
- Conditions
- Major Depressive Disorder (MDD), Suicidal Ideation, Hospitalization in Children
- Trial name
- IMPACT-D (NCT07217444)
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Suicidal Ideation, Suicidal Behavior
Understanding and Acting to Regulate Suicidal Behavior
Data from Santé Publique France show that since the onset of the health crisis (covid-19), there has been an increase in emergency room visits for mood disorders among children under 15 years of age, with a notable rise in the…
- Conditions
- Suicidal Ideation, Suicidal Behavior, Self-harm Behavior, Adolescents
- Trial name
- CARES (NCT06689657)
- Testing
- Cognitive behavioral group therapy for adolescents and non violent resistance group for parents, Adolescent group therapy (CARES) and parent group therapy (RNV)
- Volunteers
- 108 people
- Sponsor
- University Hospital, Montpellier
Substance Use, Self Esteem
Native Spirit: Significant Aim 3: Intervention
The proposed research will used community-based participatory research methods in an urban-based American Indian (AI) community to adapt, implement, and evaluate an after-school program, called Native Spirit (NS), that seeks to…
- Conditions
- Substance Use, Self Esteem, Youth Drinking, Prevention, Suicide
- Trial name
- NCT06785311
- Testing
- Native Spirit After-School Program
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Suicidal Ideation Active, Depression Disorders
Personalized TACS to Reduce Rumination in Patients with Active Suicidal Ideation
The goal of this clinical trial is to determine whether modulating default mode network (DMN) alpha connectivity using transcranial alternating current stimulation (tACS) can reduce rumination and, in turn, mitigate feelings of…
- Trial name
- Alpha-MOD (NCT06832124)
- Testing
- alpha-tACS
- Volunteers
- 50 people
- Sponsor
- Sebastian Olbrich
Suicide
Suicide Risk Interventions
The suicide rate among active duty service members and Veterans increased substantially following the onset of post-9/11 conflicts in Iraq and Afghanistan.
- Trial name
- NCT05931289
- Testing
- Enhanced Crisis Response Planning (ECRP), Brief Cognitive Behavioral Therapy for Suicide Prevention (BCBT)
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- VA Office of Research and Development
Suicidal Ideation, Suicide Attempt
Advancing Student Suicide Interventions With Scalable Technologies
Mobile-based applications, such as JasprHealth, can deliver evidence-based skills intended to reduce imminent suicide risk (e.g., reducing means access), improve emotional states (e.g., via distraction and coaching to act…
- Conditions
- Suicidal Ideation, Suicide Attempt, Self-Harm
- Trial name
- ASSIST (NCT07211373)
- Testing
- Jaspr, Behavioral support
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Massachusetts, Amherst
Suicide, Suicidal Ideation
Intensive Crisis Intervention
The study's purpose is to improve the clinical management of severe crises experienced by youth with psychiatric disorders by examining a brief, evidence-based alternative to inpatient psychiatric care.
- Conditions
- Suicide, Suicidal Ideation, Suicide, Attempted, Suicide and Self-harm
- Trial name
- ICI (NCT06476886)
- Testing
- Intensive Crisis Intervention (ICI), Adolescent Psychiatric Inpatient Unit (APIU)
- Where
- United States
- Volunteers
- 213 people
- Sponsor
- Jennifer Hughes
Suicide Prevention
HAVEN-Connect Youth Suicide Prevention
HAVEN=CONNECT is a comprehensive depression and suicide prevention intervention that is designed to be integrated into predominantly Black churches, a strategically ideal location for mental health intervention for Black youth.
- Trial name
- HAVEN (NCT07401940)
- Testing
- HAVEN-Connect, HAVEN Suicide Prevention
- Where
- 2 sites in United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- George Washington University
Healthy Volunteers, Depression
Neurobiology of Suicide
Background: There are no good treatments for people considering suicide. Researchers want to study suicide with questions, blood tests, brain imaging, and sleep studies.
- Trial name
- NCT02543983
- Testing
- Magnetic Resonance Imaging scanner, 3T, NeurOptics PLRTM-3000 Pupillometer, Experimental Anxiety Devices
- Where
- United States
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Suicide, Suicide Attempt
Nudging Parental Actions for Youth Suicide Prevention
The goal of the study is to determine effectiveness of a behaviorally informed text messaging intervention to help parents increase safety practices and reduce their teens' access to lethal means following a suicide-related…
- Trial name
- NCT07383714
- Testing
- Text-messaging for safety reminders, Text-messaging with safety reminders and risk framing
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- University of Texas Southwestern Medical Center
Suicide Attempts, Suicidal Ideation
Advancing Suicide Intervention Strategies for Teens During High Risk Periods
To inform the effective management of adolescent suicide risk by evaluating promising treatments and developing the evidence-base for interventions that are well suited for widespread adoption, sustained quality, and impact.
- Conditions
- Suicide Attempts, Suicidal Ideation, Suicide and Self-harm, Suicide Threat
- Trial name
- ASSIST (NCT05078970)
- Testing
- Safety Planning Intervention+ (SPI+), Collaborative Assessment and Management of Suicidality (CAMS), Treatment As Usual
- Where
- 2 sites in United States
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Suicidal Ideation, Regulation, Emotion
Effect of Morning Light Exposure on Mood
Mood dysregulation and suicidal ideation are closely associated with disruption of sleep and circadian rhythms. Moreover, sleep problems and circadian disruption are commonplace features of military life.
- Trial name
- NCT05616819
- Testing
- Active light exposure
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Suicidal Ideation
Evaluation of Creative Materials Supporting Healthcare Professionals in Discussing Suicidality in Children and Adolescents
Preliminary research clearly indicates a significant shortage of evidence-based tools and interventions specifically targeting suicidality among children and adolescents.
- Trial name
- NCT07043231
- Testing
- Creative materials
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Ghent
Suicidality, EEG
Nitrous Oxide in the Treatment of Acute Suicidal Ideation
The primary aim of the NITOS study is to investigate the potential rapid antisuicidal effects of N2O in the transdiagnostic treatment of suicidal ideation.
- Conditions
- Suicidality, EEG, Suicidal Ideation, Nitrous Oxide
- Trial name
- NITOS (NCT06636357)
- Testing
- 50% N2O plus 50% O2, Oxygen (O2)
- Where
- Switzerland
- Volunteers
- 85 people
- Sponsor
- University of Zurich
Suicide, Attempted
Efficacy of EBPSI on Future Suicide Risk Among Adolescent Suicide Attempters
Our study is designed to study the efficacy of an Electronic based psycho-social intervention targeting healthy coping and problem solving skills to mitigate suicidal behaviour.
- Trial name
- NCT06474221
- Testing
- Electronic Based Psychosocial Intervention (EBPSI)
- Where
- 2 sites in India
- Volunteers
- 168 people
- Sponsor
- University of Pittsburgh