Clinical trials: Self-injurious Thoughts and Behaviours
Suicidal Thoughts and Behaviors, Social Connectedness
Social Threat, Adolescent Relationships, and Suicidality Study
In recent years, adolescents are having higher rates of emotional health problems, such as suicidal thoughts and behaviors (STBs).
- Conditions
- Suicidal Thoughts and Behaviors, Social Connectedness, Responses to Social Threat
- Trial name
- STARS (NCT07294079)
- Testing
- Social threat
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Pittsburgh
Suicidal Ideation, Suicide, Attempted
A Conditioning Paradigm to Increase Affinity for Sacredness of Life
Suicide-related experiences affect millions of people every year in the United States. Through decades of research, interventions targeting these experiences have developed with varied empirical support.
- Conditions
- Suicidal Ideation, Suicide, Attempted, Suicide and Self-harm, Non-suicidal Self-injury
- Trial name
- NCT05541900
- Testing
- TEC-Sacredness, TEC-Control
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Florida State University
Substance Use Disorders, Depression
Study of a Transdiagnostic, Emotion-focused Group Intervention for Young Adults With Substance Use Disorders
The overall aim of this pilot study is to conduct a preliminary trial to evaluate the acceptability and feasibility of adding a transdiagnostic, emotion-focused group intervention (the Unified Protocol, UP) to treatment as usual…
- Conditions
- Substance Use Disorders, Depression, Anxiety, Emotional Disorder
- Trial name
- ARMS UP (NCT03315208)
- Testing
- Unified Protocol (UP), Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Massachusetts General Hospital
Suicidal Thoughts and Behaviors
Standardized Adaptive Music Medicine for Suicidality
The primary goal of this clinical trial is to test if music-based intervention (STAMM-S) works for individuals with suicidal thoughts or behaviors.
- Trial name
- STAMM-S (NCT07610785)
- Testing
- STAMM-S
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Stanford University
Alcohol Use, Suicidal Ideation/Behavior
Examining the Relationship Between Ongoing Alcohol Use, Suicidal Thoughts and Behaviors and Related Constructs, and Behavioral Economic Decision-Making
The purpose of this single groups trial is to (Aim 1) determine relationships between alcohol use, suicidal thoughts and behaviors (STBs), and behavioral economic decision-making in a community sample (N = 100) of alcohol using…
- Trial name
- NCT06845761
- Testing
- Self-Guided Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Mark J Rzeszutek, PhD
Suicidal Ideation, Hopelessness
Randomized Controlled Trial of a Single-session Mechanism-focused Intervention for Suicidal Thoughts and Behaviors
Across multiple models of suicide risk, hopelessness and perceptions of social relatedness (i.e., lack of social connection/thwarted belongingness, perceived burdensomeness) have emerged as candidate mechanisms that maintain…
- Conditions
- Suicidal Ideation, Hopelessness, Wish to Live, Wish to Die
- Trial name
- NCT05816317
- Testing
- Single-Session Mechanism-Focused Intervention (SSMFI), Distress Tolerance Skills Review
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Shannon E. Sauer-Zavala
Suicide, Mental Health Disorder
Optimizing a Just-in-time Adaptive Intervention for Suicide Safety Planning in Adolescents
Despite efforts to prevent suicide, US rates are climbing, and suicide is the second leading cause of death amongst youth. Digital tools, especially personal smartphones, are promising avenues to address these issues and can be…
- Conditions
- Suicide, Mental Health Disorder, Anhedonia
- Trial name
- NCT06665620
- Testing
- ViraBrite nudges
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Ksana Health
Suicidal Thoughts and Behaviors
From Court to the Community
Youth involved in the juvenile justice system evidence disproportionately high rates of suicidal thoughts and behavior (STB) and non-suicidal self-injury (NSSI) compared to adolescents in the general population.
- Trial name
- JJ-COPES (NCT06227169)
- Testing
- JJ-COPES Training
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Suicide
Tool for Sibling and Children of Someone With Suicidal Thoughts
This study aims to investigate to what extent a website developed for siblings and children (16-25 years old) of someone with suicidal thoughts and/or behaviors is effective in improving perceived pressure, knowledge, attitudes…
- Trial name
- NCT06100575
- Testing
- Website (www.mee-leven.be)
- Where
- Belgium
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University Ghent
Supportive Messages, Control
You Belong and You Matter: An Exploration of Self-injurious Thoughts and Behaviors in LGTBQ+ Individuals
Individuals with minoritized sexual and gender identities (i.e., LGBTQ+ individuals) are at a greater risk for self-injurious thoughts and behaviors than their cisgender, straight peers (Haas et al., 2010; Liu et al., 2017…
- Trial name
- NCT07218861
- Testing
- Supportive Messages
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Konrad Bresin
Self-Injurious Behavior, Suicidal Ideation
Therapeutic Evaluative Conditioning to Reduce Adolescents' Self-injurious Thoughts and Behaviors During and After Psychiatric Inpatient Hospitalization
Suicide is the 2nd leading cause of death among adolescents, with the highest risk period for suicide being the month following psychiatric inpatient hospitalization.
- Conditions
- Self-Injurious Behavior, Suicidal Ideation, Suicide Attempts
- Trial name
- TEC (NCT05796531)
- Testing
- Therapeutic Evaluative Conditioning, Neutral comparison condition
- Where
- United States
- Volunteers
- 155 people
- Sponsor
- Franciscan Hospital For Children, INC.
Suicidal Thoughts and Behaviors
Developing and Testing a Brief, Personalized Intervention for Suicidal Thoughts and Behaviors
Suicide is a leading cause of death in the United States and around the world. Individuals at high-risk for suicide are heterogenous.
- Trial name
- AFSP_PRECISE (NCT07749391)
- Testing
- PRECISE
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of California, San Diego
Suicidal Thoughts and Behaviors, Social Isolation
Qnnections: Refinement and Pilot Trial of a Suicide Prevention Intervention to Increase Social Connection
Despite the high risk of suicide among LGBTQ+ Veterans, there is currently no suicide-focused intervention for this population. This study will refine and pilot Qnnections, a novel group-based suicide prevention intervention that…
- Trial name
- Qnnections (NCT06803329)
- Testing
- Qnnections, Enhanced Usual Care
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- VA Office of Research and Development
Suicide, Attempted, Suicide Threat
Written Exposure Therapy for Suicide Prevention
Military service members admitted to inpatient psychiatry for self-injurious thoughts and behaviors (SITBs) represent an at-risk group for continued SITBs and rehospitalizations in the post-discharge period.
- Trial name
- NCT05878795
- Testing
- WET-SP, TAU
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Boston University
Suicide Prevention, Suicidal Ideation
Co-creation of Tools for Children and Adolescents with Suicidal Thoughts And/or Behaviour
Evidence shows that there are very few evidence-based tools or interventions specifically targeting suicidality in children and adolescents.
- Conditions
- Suicide Prevention, Suicidal Ideation, Suicidal Behaviors
- Trial name
- Co-crea K&J (NCT06776328)
- Testing
- Tools
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- University Ghent
Alcohol Use Disorder (AUD), Suicidal Ideation
Examining the Relationship Between Ongoing Alcohol Use, Suicidal Thoughts and Behaviors and Related Constructs, and Behavioral Economic Decision-Making.
This study will evaluate the relationship between alcohol use, suicidal thoughts and behaviors, and behavioral economic decision-making.
- Trial name
- NCT07842588
- Testing
- CBT4CBT
- Volunteers
- 180 people
- Sponsor
- Mark J Rzeszutek, PhD
PTSD, Suicidal Thoughts and Behaviors
Cannabis, Neuroinflammation, and Suicidal Ideation: A Supplemental Brain Imaging Study
This study will be the first to use brain imaging to explore how cannabis affects the brain and inflammation in U.S. military veterans with PTSD.
- Conditions
- PTSD, Suicidal Thoughts and Behaviors, PTSD Symptoms, Depressive Symptoms
- Trial name
- CNS (NCT07222306)
- Testing
- 1-(2-[+F]fluoroethyl)-L-tryptophan
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Wayne State University
Suicidal Thoughts and Behaviors
Development of PRECISE: A Data Driven Personalized Suicide Prevention Intervention
Individuals at high-risk of suicide vary substantially from one another. Over time, risk factors for suicide may change within the same individual.
- Trial name
- NCT06809348
- Testing
- PRECISE
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of California, San Diego
Covid19, Mental Health Disorder
MIND/COVID-19: Mental Health Impact and NeeDs Associated With COVID-19: a Comprehensive National Evaluation in Spain
The aim of the proposed project is to provide a comprehensive assessment of the mental health impact of the ongoing COVID-19 outbreak in Spain.
- Conditions
- Covid19, Mental Health Disorder, Mental Health Conditions
- Trial name
- NCT04556565
- Where
- 18 sites in Spain
- Volunteers
- 16,000 people, healthy volunteers welcome
- Sponsor
- Jordi Alonso
Self-injurious Thoughts and Behaviours, Borderline Personality Disorder
Development and Initial Testing of a Couple-Based Intervention to Optimize Suicide and Self-Injury Treatment: COMPASS (Connecting, Overcoming, and Moving Past Suicide and Self-Injury)
Self-injurious thoughts and behaviors (SITBs), including suicide, thinking about suicide, and self-injury without intent to die, are major public health crises, with variably effective, and sometimes long and expensive…
- Trial name
- COMPASS (NCT04737252)
- Testing
- Sage (formerly known as COMPASS)
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- York University