Clinical trials: Semen Quality
Sperm Quality, Oligoasthenospermia
Effect of Treatment With Myo-inositol on Human Semen Parameters in Patients Undergoing In Vitro Fertilization Cycles
Myo-Inositol (MI) is a precursors for the synthesis of phosphatidylinositol polyphosphates (PIPs). In male reproduction, it was shown that MI concentration in the seminiferous tubules is higher than in serum and it was increasing…
- Trial name
- NCT01560065
- Testing
- myo-inositol + folic acid
- Where
- Italy
- Sponsor
- AGUNCO Obstetrics and Gynecology Centre
Crohn's Disease, Ulcerative Colitis
The Effect of Infliximab on Sperm Quality
Background: The treatment of inflammatory bowel diseases (IBD) is based mainly on 3 compounds: 1- 5 aminosalysilates . 2- immunomodulators (Azathioprines). 3- Biologic therapies (Infliximab, Adalimumab) .
- Trial name
- NCT00745329
- Testing
- sperm quality test
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Sperm Cryodamage
Effect of PRP in Donor Semen During Cryoprervation
Sperm cryopreservation allows the preservation of sperm biological function for long periods of time for later use in assisted reproductive techniques (ART).
- Trial name
- PRP (NCT07504575)
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI Alicante
Fertility, Male Fertility
Sperm, Exposure and Endocrine Disruptors
The proposed research aims to 1) measure male participants' urinary levels of EDCs and sperm quality before and after report-back and EDC reduction intervention and assess changes, 2) assess the extent to which MM's program…
- Conditions
- Fertility, Male Fertility, Sperm Count, Low, Sperm Quality
- Trial name
- SEED (NCT07703046)
- Testing
- EDC Education Intervention
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Million Marker Wellness, Inc.
Neoplasms, Prostate
Quality of Life After Permanent Interstitial Iodine Seed Prostate Brachytherapy
Retrospective study to analyze Quality of life in men after iodine seed brachytherapy for localized prostate cancer
- Trial name
- NCT02652000
- Testing
- No intervention in this retrospective study
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Kantonsspital Graubünden
Male Infertility
A Clinical Evaluation of Semen Quality Using the MiOXSYS™ System 2.0
The purpose of this study is to determine if elevations in oxidative stress, as measured by oxidation-reduction potential (ORP), can distinguish between semen samples from men with abnormal semen parameters from those with normal…
- Trial name
- NCT02839447
- Testing
- Diagnostic
- Where
- 6 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Aytu BioPharma, Inc.
Urothelial Carcinoma Bladder, Sperm Count, Low
Effect of Intravesical B.C.G and Gemcitabine on Semen Analysis and Testicular Volume in NMIBC
To evaluate the effects of local intravesical B.C.G and gemcitabine on semen quality and testicular volume.
- Conditions
- Urothelial Carcinoma Bladder, Sperm Count, Low, Testis; Fibrosis, Non Muscle Invasive Bladder Cancer
- Trial name
- NCT05701332
- Testing
- Bacillus Calmette Guerin, Gemcitabine HCL (Gemzar)
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Assiut University
Poor Semen Quality
Effects of Plant Extracts on Semen Quality
this is a prospective randomized placebo-controlled double-blinded trial investigating the effect of plant extracts from Alpinia galanga and Punica granatum on human semen quality.
- Trial name
- NCT01357044
- Testing
- Extracts of Punica granatum and Alpinia galanga
- Where
- Denmark
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Horsens Hospital
Sperm Quality
Evaluation of the Effects of Certolizumab Pegol on Semen Quality in Healthy Male Volunteers
The primary objective of this study is to evaluate the effect of certolizumab pegol (CZP) on the quality of sperm obtained from healthy male volunteers.
- Trial name
- NCT01091220
- Testing
- Certolizumab pegol
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- UCB Pharma
Spermatogenesis and Semen Disorders, Infertility, Male
Power Prenatal Supplements for Sperm Quality
Male factor infertility is a leading cause of primary and secondary infertility. Poor sperm quality is defined as having an abnormal semen analysis [WHO 2020 - https://www.who.int/publications/i/item/9789240030787].
- Trial name
- NCT05410782
- Testing
- Power Prenatal for Sperm
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The Bird and Be Co Inc
Semen Quality
Sperm Quality in Consecutive Sperm Samples After 4-7 Days and 2 Hours of Sexual Abstinence
The main purpose of the study is to assess to which degree a series of sperm parameters known to be associated with fertilization and implantation potential in artificial reproductive technology (ART) differ in consecutive sperm…
- Trial name
- NCT02667080
- Testing
- 2-7 days of Sexual abstinence, 2 hours of sexual abstinence
- Where
- Denmark
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Infertility
Effect of Omega 3 Fats on Sperm Quality and Sexual Function
This study compares the effects of omega 3 fats plus folic acid with placebo plus folic acid on sperm quality and sexual function in infertile men.
- Trial name
- NCT00406874
- Testing
- omega 3 fats, folic acid
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Reproductive Partners Medical Group
Infertility, Male
Assessment of TetraSOD® Efficacy to Improve Semen Parameters in Men With Idiopathic Infertility
TetraSOD® is a unique marine phytoplankton (Tetraselmis chuii) SOD-rich ingredient that is grown under patent-protected technology exclusively designed by the company Fitoplancton Marino, S.L. (Spain).
- Trial name
- NCT04864314
- Testing
- Marine microalgae Tetraselmis chuii with high Superoxide Dismutase (SOD) activity
- Where
- 2 sites in Spain
- Volunteers
- 80 people
- Sponsor
- Fitoplancton Marino, S.L.
Health Effects of Aronia
Potential Health Effects of Aronia Intake
Intervention cross-over study during which participants receive standardized amounts of aronia berry tablets or placebo for three months, then wash out for three months, then aronia tablets or placebo for three months.
- Trial name
- NCT03405753
- Where
- Denmark
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Semen Quality in Healthy Adult Men
Effects of 12-Week Combined Exercise on Semen Quality and Metabolic Health in Healthy Men
This study evaluated whether a 12-week combined aerobic and resistance exercise program could improve semen quality and metabolic health in healthy adult men. A total of 34 men aged 18-24 years participated in the study.
- Trial name
- NCT07778576
- Testing
- Combined Aerobic and Resistance Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Semen Quality
The Effects of Microgravity on Human Sperm
It has been described that microgravity affects cellular and molecular structures. Cell membrane, cytoskeleton, cytoplasm and nucleus have been found to be sensible to gravitational changes.
- Trial name
- NCT03760783
- Testing
- Parabolic flight
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fundacion Dexeus
Infertility, Male
The Effect of a Multimodal Lifestyle Program on Male Fertility
A non-pharmacological study, which examines the effect of lifestyle intervention on sperm quality among men in fertility treatment.
- Trial name
- NCT04761250
- Testing
- Lifestyle
- Where
- Denmark
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Peter Humaidan
Infertility, Male
Abstinence Period and Semen Quality
Does period of abstinence impact progressive motility in oligoasthenoteratozoospermic (OATS) males? In the evaluation of male fertility, semen analysis is an important investigation.
- Trial name
- NCT04955782
- Testing
- samples will be analyzed for semen volume, pH, count, concentration, motility, morphology and viability
- Where
- Oman
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Male Infertility, Heart Valve Disease
Warfarin Effects on Male Fertility After Cardiac Surgery
Young male patients undergoing cardiac surgery may require oral anticoagulation with warfarin either lifelong, such as after mechanical valve replacement, or for a limited postoperative period, for example following valve repair…
- Trial name
- NCT07330869
- Testing
- Semen analysis, sperm DNA fragmentation and hormonal evaluation
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Città di Lecce Hospital, GVM Care & Research
Prostatic Neoplasms, Cancer of the Prostate
Hemi-Ablative Prostate Brachytherapy
This clinical study will evaluate side effects, quality of life and cancer control in patients with prostate cancer diagnosed on only one side of the prostate gland.
- Trial name
- HAPpy (NCT02632669)
- Testing
- Hemigland focal LDR brachytherapy
- Where
- United Kingdom
- Volunteers
- 31 people
- Sponsor
- Royal Surrey County Hospital NHS Foundation Trust