Clinical trials: Sense of Control
Hyperalgesia
A Study Of GSK189254 And Duloxetine In The Electrical Hyperalgesia Model Of Healthy Volunteers
GSK189254 is a highly potent histamine 3 (H3) receptor antagonist which has demonstrated efficacy in the reduction of mechanical hyperalgesia and allodynia in the chronic constriction injury pre-clinical model of neuropathic pain…
- Trial name
- NCT00387413
- Testing
- Duloxetine, GSK189254
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Fear Pain
Human Behaviors Related to the Expectation of Pain
The conditioned expectation of pain is an important aspect of pain-related disability produced by environments and stimuli associated with a painful injury on the job, although the neuroscience of this expectation is unclear.
- Trial name
- NCT03739645
- Testing
- Skin conductance levels and slopes over time in conditioned fear as metrics.as metrics for anxiety
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Exercise Therapy
The Effects of Pilates-based Exercises on the Posterior Leg Muscles
This randomized controlled study aims to investigate the effects of a pilates-based exercise program on hamstring flexibility, plantar pressure sensation, and dynamic balance in university students aged 18 to 24 years.
- Trial name
- NCT07146724
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Yalova
Tinnitus
Impact of Neurostimulation on Patterns of Brain Electrical Activity in Patients With Tinnitus
Relating the electroencephalogram findings of patients with tinnitus before and after a therapeutic modality is still scarce in the literature, especially with neuromodulatory methods, more specifically with Transcranial Direct…
- Trial name
- NCT03036137
- Testing
- Transcranial Direct Current Stimulation
- Where
- Brazil
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Federal University of Paraíba
Cold Exposure, Body Temperature Regulation
Hand Cooling With Ice Packs in Healthy Young Men
This randomized, parallel-group study looked at how a standard 15-minute ice pack applied to the back of the hand affects skin temperature and how cold and comfortable the hand feels, compared with a room-temperature water pack.
- Conditions
- Cold Exposure, Body Temperature Regulation, Thermal Comfort Perception
- Trial name
- ICEHAND (NCT07254182)
- Testing
- Ice Pack (Localized Cryotherapy), Thermoneutral Water Pack (Control)
- Where
- Poland
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Hearing Loss, Motivation
Motivational Interviewing in Hearing Aid Users
Hearing loss is one of the most common chronic disabilities in the older adult population and affects their quality of life. Hearing aid use can improve one's quality of life by increasing a person's ability to detect…
- Conditions
- Hearing Loss, Motivation, Hearing Disability, Hearing Disorders and Deafness
- Trial name
- MI-HAT (NCT04673565)
- Testing
- Motivational interviewing
- Where
- Canada
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Healthy, Overweight
Study to Evaluate the Effect of Gum Acacia (FibregumTM) on Post-prandial Glucose, Insulin Levels and Food Intake
Study to evaluate the effect of gum acacia (FibregumTM) on post-prandial glucose and insulin levels and food intake in normal-weight and overweight subjects during a 2-7 weeks intervention period.
- Trial name
- NCT04515277
- Testing
- 40 g Gum acacia (FibregumTM), 20 g Gum acacia (FibregumTM), 0 g Gum acacia (FibregumTM)
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Nexira
Hyperalgesia, Allodynia
Fenobam on Heat/Capsaicin Induced Hyperalgesia in Healthy Volunteers
Our goal is to demonstrate that healthy volunteers treated with fenobam will develop a significantly reduced area of cutaneous hyperalgesia compared to volunteers treated with placebo, after exposure to the heat/capsaicin model…
- Trial name
- NCT01981395
- Testing
- Fenobam
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Laura Cavallone
Healthy, Hyperalgesia
A Safety Tolerance and Experimental Hyperalgesia Study of Oral NGX426 in Healthy Male Voluneteers
The purpose of this study is to determine the effects of NGX426 on intradermal capsaicin induced pain in hyperalgesia.
- Trial name
- NCT00832546
- Testing
- Oral NGX426 (Powder in solution)
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- TorreyPines Therapeutics
SARS-CoV Infection, COVID-19
Malaysian COVID-19 Anosmia Study (Phase 2) - A Nationwide Multicentre Case-Control Study
The Malaysian COVID-19 Anosmia Study is a nationwide multicentre observational study to investigate the prevalence and characteristics of olfactory and gustatory/taste disturbances in COVID-19 infection in Malaysia, and to…
- Conditions
- SARS-CoV Infection, COVID-19, Anosmia, Dysgeusia
- Trial name
- NCT04384042
- Testing
- Patient-Reported Online Questionnaire on Olfactory & Taste Disturbances
- Where
- 14 sites in Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital Sultanah Bahiyah
Hearing Loss
Impact of Oral Health Education on Oral Hygiene Status of Deaf Children
Objective: To compare the impact of pictorial and video demonstration oral health educational interventions on oral hygiene status of children aged 12-16 years with hearing impairment.
- Trial name
- NCT05099146
- Testing
- pictures, video, control
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Benign Paroxysmal Positional Vertigo
Canalith Repositioning Procedure for BPPV in Primary Care
The purpose of this study is to see whether family doctors can treat benign paroxysmal positional vertigo (BPPV), or dizziness, using a procedure in the office.
- Trial name
- NCT00182273
- Testing
- Canalith repositioning maneuver (CRM)
- Where
- Canada
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- McMaster University
Energy Intake, Gastrointestinal Hormones
Effects of Oral Xylitol on Subsequent Energy Intake
The aim of this project is to investigate the effect of xylitol (given as pre-load), compared to sucrose, Ace-K, and water on energy intake during a subsequent ad libitum test meal in healthy participants.
- Conditions
- Energy Intake, Gastrointestinal Hormones, Glycemic Control, Appetite
- Trial name
- NCT05671965
- Testing
- Xylitol, Sucrose, Acesulfame Potassium
- Where
- Switzerland
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Focus of Study is Effects of Neuromuscular Training, Postural Balance
Effects of Cervical Sensorimotor Training With Pilates Reformer on Balance and Cervical Joint Position Sense
This study investigates the effects of Pilates reformer exercise combined with cervical sensorimotor training using laser-guided visual feedback on balance performance.
- Conditions
- Focus of Study is Effects of Neuromuscular Training, Postural Balance, Pilates
- Trial name
- NCT07483892
- Testing
- Cervical Sensorimotor Training, Pilates Reformer Exercise
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ewha Womans University
Burning Nose
Using Intranasal Midazolam (INM) and Lidocaine for Uncooperative Children
Aims: The objective of the current study was to evaluate the effectiveness of topical lidocaine in relieving pain related to INM administration. Design: This was a blinded, randomized placebo-controlled trial.
- Trial name
- INM (NCT03725995)
- Testing
- Midazolam, Lidocaine-Midazolam
- Where
- Syria
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Latakia University
Visual Impairment, Age-Related Macular Degeneration (AMD)
Prevalence and Determinants of Shoulder Girdle Musculoskeletal Complaints in Geriatric Patients With Diminished Vision
This case-control study aims to investigate the prevalence and determinants of shoulder girdle musculoskeletal complaints (pain, spasm, stiffness, range of motion impairments) in geriatric patients (aged 60+) with diminished…
- Conditions
- Visual Impairment, Age-Related Macular Degeneration (AMD), Musculoskeletal Pain, Shoulder Pain
- Trial name
- NCT07206654
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Healthy
Effects of Itopride on Gastric Motor and Sensory Functions in Healthy Volunteers
Itopride is a new compound that is already marketed in Japan and in some countries of Eastern Europe under the name of Ganaton. It is used to treat symptoms associated with gastroparesis.
- Trial name
- NCT00370110
- Testing
- Itopride 100 mg, Itopride 200 mg
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Forest Laboratories
Thermal Injury, Skin Burn
Gellan Contact Study
The primary objective of this study will be to establish the safety of the two different Gellan formulations (sheet and fluid gel) following its application to the epidermis of healthy volunteers.
- Trial name
- GCS (NCT04044014)
- Testing
- Gellan sheet, Gellan fluid gel, Mepitel One
- Where
- United Kingdom
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Fear of Birth, Birth Memory
Emotional Freedom Technique During Pregnancy
Emotional Freedom Technique (EFT), also known as "Tapping Therapy" and "Needleless Acupuncture", is a new and emerging complementary and energy-based therapy.
- Conditions
- Fear of Birth, Birth Memory, Postpartum Sense of Security
- Trial name
- NCT07000552
- Testing
- EFT intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- KTO Karatay University
Tinnitus, Subjective, Hearing Impairment
Efficacy of Amplification With Hearing Aids for Tinnitus Relief
This study evaluates the treatment efficacy of tinnitus in people with mild hearing loss. One-third of participants will use hearing aid, one-third of participants will use customized music, while the other one-third participants…
- Trial name
- NCT03716544
- Testing
- Amplification with hearing aid, Customized music
- Where
- Hong Kong
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Education University of Hong Kong