Clinical trials: Sensitive Dentin
Pain, Dentin Sensitivity
Effect of an Experimental Gel Containing Copaiba Oil-resin in the Control of Dentin Hypersensitivity
This randomized, single-blind, placebo-controlled clinical trial aims to clinically evaluate the effect of an experimental gel containing copaiba oleo-resin in the control of dentin hypersensitivity (DH) in non-carious cervical…
- Conditions
- Pain, Dentin Sensitivity, Dentin Desensitizing Agents
- Trial name
- NCT06872749
- Testing
- KF2 (Potassium nitrate gel), experimental Copaiba gel
- Where
- Brazil
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Tooth Sensitivity, Teeth Whitening
Bioadhesive Film of Acmella Oleracea (Jambu) in the Reduction of Post-bleaching Dental Sensitivity Caused by Bleaching With 35% Hydrogen Peroxide.
Despite the wide range of desensitizing agents available on the market, there is still no gold standard treatment that is fully effective in managing sensitivity by dental bleaching.
- Trial name
- NCT07478640
- Testing
- Bioadhesive film of Acmella Oleracea (jambu), Gel containing 5% potassium nitrate and 2% sodium fluoride., Spilanthol-free bioadhesive bioplastic film
- Where
- Brazil
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Tooth Hypersensitivity
Effect of Different Desensitizing Agents on Post-bleaching Hypersensitivity and Shade Stability
This study compared the effect of four different desensitizing agents on shade stability and dental hypersensitivity following dental bleaching procedure. The follow-up periods ranged from 24 hours to 1 year.
- Trial name
- NCT06358924
- Testing
- Potassium nitrate with fluoride, Casein phosphopeptide-amorphous calcium phosphate with fluoride, Hydroxyapatite with fluoride
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Dentin Hypersensitivity
The Effects of Different Dentin Hypersensitivity Treatment Methods on Quality of Life
The aim of this study was to evaluate the effects of a self etch adhesive resin and two desensitizing agents(Calcium phosphate, 5% glutaraldehyde) in treatment of dentin hypersensitivity on the quality of life of individuals.
- Trial name
- NCT04887181
- Testing
- Teethmate Desensitizer, Gluma Desensitizer, Hybrid Bond
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Dentin Sensitivity
A Clinical Study to Evaluate the Anti-Sensitivity Efficacy of a Stannous Fluoride Toothpaste in a Population of Dentin Hypersensitivity Sufferers
The aim of this study is to confirm the clinical Dentin Hypersensitivity (DH) efficacy of a 0.454 percent (%) Stannous Fluoride (SnF2) toothpaste.
- Trial name
- NCT06354270
- Testing
- Stannous fluoride toothpaste, Regular fluoride toothpaste (Crest Cavity Protection)
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- HALEON
Sensitivity, Tooth
Efficacy of Tooth Bleaching With 35% and 6% Hydrogen Peroxide in Primary Dentition
The aesthetics of dental elements generates great psychological and social impacts, both in the deciduous and permanent dentition. One of the techniques widely used to visually improve the appearance of teeth is bleaching.
- Trial name
- NCT05789004
- Testing
- Tooth Bleaching with Whiteness HP Automixx 35%, Tooth Bleaching with Whiteness HP Automixx 6%
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Dentin Hypersensitivity, Periodontal Diseases
Comparative Clinical Evaluation of Three Different Agents in Reducing Dental Hypersensitivity in Periodontal Patients
The present project will compare the effect of DH reduction using three different dentifrices (Sensodyne Repair and Protect - NOVAMIN technology; Dentalclean Daily Regenerator - REFIX technology; Dentalclean Daily Regenerator …
- Trial name
- NCT04422184
- Testing
- Sensodyne Repair and Protect, Dentalclean Daily Regenerator, Dentalclean Daily Regenerator with potassium citrate
- Where
- Brazil
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Dentin Sensitivity
Assessment of the Efficacy of an Experimental Occlusion Technology Dentifrice in Dentinal Hypersensitivity
This study will evaluate the effectiveness of an experimental dentifrice containing stannous fluoride, an established dentine tubule occlusion technology, at reducing dentine hypersensitivity (DH) compared to a negative control…
- Trial name
- NCT02861664
- Testing
- Stannous fluoride (SnF2), Sodium monofluorophosphate (SMFP)
- Where
- China
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dentin Hypersensitivity
Efficacy of Seventh Generation Bonding Agents as Short-Term Desensitizers Among Patients With Hypersensitivity
The world lacks a gold standard treatment for treating dentin hypersensitivity. Fluoride varnish is most commonly used as a treatment but it causes temporary discoloration of tooth structure and may cause irritation or burning of…
- Trial name
- NCT04225247
- Testing
- Single Bond Universal, Bifluorid 12, Xeno V+
- Where
- Pakistan
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Dental Restoration Failure of Marginal Integrity
Influence of Surface Sealants on the Quality of Posterior Restorations With Bulk Fill Composites
Treatment clinical trial, randomized, controled, parallel, double-blinded, with three groups, that aims to evaluate if there is some advantage in applying surface sealants (Biscover, Bisco, USA or Permaseal, Ultradent, USA)…
- Trial name
- SEALBULK (NCT03924830)
- Testing
- Bulk without surface sealant, Bulk with Biscover, Bulk with Permaseal
- Where
- Brazil
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Dentin Sensitivity
A Clinical Study to Determine the Safety and Effectiveness of Dentinal Hypersensitivity Treatment With Two Different Toothbrushes
This study will determine the effects toothbrush type (power or manual) has on the safety and effectiveness of professional dentinal hypersensitivity treatment with a marketed oxalate-containing solution.
- Trial name
- NCT02513212
- Testing
- Potassium Oxalate, Stannous fluoride paste, Manual toothbrush
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Tooth Discoloration
Effects of Bio-active Desensitizer on Reduction of Tooth Sensitivity Caused by In-office Bleaching.
The main aim of this randomized controlled clinical trial is to evaluate the efficacy of a bioactive glass desensitizer in reducing tooth sensitivity associated with in-office vital tooth bleaching.
- Trial name
- NCT06532526
- Testing
- Predicta® Bioactive Desensitizer (PBD, PARKELL, EDGEWOOD, NY, USA), Gel with 1.23% sodium fluoride (EAZIGEL, VERICOM CO., LTD. SOUTH KOREA)
- Where
- Jordan
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Tooth Sensitivity, Toothache
Piroxicam-beta-Cyclodextrin on Tooth Sensitivity Caused by In-office Bleaching
Objectives: This study aims to evaluate the effectiveness of preemptive administration of non-steroidal anti-inflammatory Piroxicam-beta-Cyclodextrin on risk and level of tooth sensitivity caused by in-office bleaching procedures…
- Trial name
- NCT03153657
- Testing
- Piroxicam-Beta-Cyclodextrin
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sergipe
Teeth Sensitivity
Comparison in Marginal Adaptation Between Conventional and Gull Wing Preparation in Laminates Veneers
The aim of this study is to evaluate tooth sensitivity and marginal adaptation of porcelain laminates veneers prepared with modified gull wing preparation and conventional preparation.
- Trial name
- NCT03214549
- Testing
- gull wing preparation of laminates veneers, conventional preparation of laminates veneers
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dentin Sensitivity
A Study to Assess Efficacy of an Experimental Oral Rinse in Providing Long Term Relief From Dentinal Hypersensitivity
To investigate the efficacy of an experimental oral rinse, containing 1.5% potassium oxalate (KOX) and 0 parts per million (ppm) fluoride in relieving dentine hypersensitivity (DH) after 8 weeks use compared with a placebo oral…
- Trial name
- NCT03238352
- Testing
- Potassium oxalate, Sodium fluoride
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Caries, Salivary Function
Lesion Progression After Icon Treatment in Young Adults
This is a three year single site clinical evaluation of a FDA approved (510(k):K100062) lesion penetrating resin used to infiltrate and hamper progression of proximal carious lesions.
- Conditions
- Caries, Salivary Function, Tooth Sensitivity
- Trial name
- NCT01988337
- Testing
- Resin infiltration, Mock treatment
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- DMG Dental Material Gesellschaft mbH
Dentin Sensitivity
Evaluation of the Effectiveness of Home-Use Desensitizing Agents on Dentin Hypersensitivity
Dentin sensitivity is one of the most common problems in society and affects the quality of life related to oral health. Agents such as toothpaste, mouthwash, and dental cream are home-type desensitizing agents used as the first…
- Trial name
- NCT06216262
- Testing
- Control group, Arginine, Novamin
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Dentin Sensitivity, Molar Incisor Hypomineralization
Control of Pain Due to Dentin Hypersensitivity in Individuals With Molar-incisor Hypomineralization
Background: Dentin hypersensitivity (DH) is defined as high sensitivity of the vital dentin when exposed to thermal, chemical or tactile stimuli.
- Trial name
- NCT04407702
- Testing
- Hygiene Instructions, Sealant application, Low-level Laser
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Carious Dentin
Postoperative Hypersensitivity and Digital Radiographic Assessment of a Zinc Modified Versus a Conventional Glass Ionomer Cement in Deep Carious Lesion: Randomized Controlled Clinical Trial
The study aim to evaluate the difference between the effect of zinc modified glass ionomer and conventional glass ionomer on the success of partial caries removel technique
- Trial name
- NCT03285022
- Testing
- Partial caries removel techniques
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Restoration Failure of Marginal Integrity
Clinical Evaluation of Bulk Fill Composite Restorations Associated to Universal Adhesive System
Treatment clinical trial, randomized, controled, parallel, double-blinded, with four groups, that aims to evaluate the best application strategy when using a Universal Adhesive system, Single Bond Universal (3M ESPE, USA), in…
- Trial name
- FBFSBU (NCT03343184)
- Testing
- SEE Strategy and Incremental Restoration, SEE Strategy and Bulk Fill Restoration, SET Strategy and Incremental Restoration
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense