Clinical trials: Sensory Function
Deafness
Neurophysiological Measures of Auditory Perception and Rehabilitation in Cochlear Implanted Patients
This study aims at investigating new automatic fitting techniques for cochlear implant patients based on objective measures. For this reason, the evolution of these neurophysiological measures, expressing the encoding of pure…
- Trial name
- NEUROSYLLABIC (NCT02323256)
- Testing
- Auditory steady-state response ASSR, Speech-ABR, Acoustic Change Complex ACC
- Where
- France
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Age-related Macular Degeneration, Aging
Functionally Validated Structural Endpoints for Early AMD
Delayed rod-mediated dark adaptation (RMDA), or delayed recovery of vision in a dark environment, is a functional biomarker (i.e., risk factor) for early age-related macular degeneration (AMD).
- Trial name
- ALSTAR2 (NCT04112667)
- Testing
- Normal Macular Health, Early Macular Degeneration, Young Normals
- Where
- United States
- Volunteers
- 556 people, healthy volunteers welcome
- Sponsor
- Cynthia Owsley
Healthy Subjects
Effect of High-dose Target-controlled Naloxone Infusion on Pain and Hyperalgesia During a Burn Injury
In several rodent studies, it has been demonstrated that very high doses of opioid antagonists (i.e., naloxone 3-10 mg/kg) administered after weeks after recovery from an inflammatory injury may lead to a reinstatement of…
- Trial name
- TCI-NX-BI (NCT02684669)
- Testing
- Naloxone, Normal saline
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- mads u werner
Obesity
Auditory Sensory Attenuation in Obesity
The goal of this observational cross-sectional study is to test the sensory attenuation effect with auditory stimuli comparing women with obesity and healthy-weight women.
- Trial name
- Ud_SA_OB (NCT06298539)
- Where
- Italy
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Istituto Auxologico Italiano
Viral Respiratory Tract Infection, Influenza
Use of Wearable Sensors for Early Detection and Tracking of Viral Respiratory Tract Infections
Viral respiratory tract infections (VRTI) are among the most common human illnesses, impacting billions globally. There is an unmet need to identify novel ways to detect, treat and prevent their spread.
- Trial name
- WE SENSE (NCT05290792)
- Testing
- Administration of FluMist (Live Attenuated Influenza Vaccine)
- Where
- Canada
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Emily McDonald
Taste Disorders, Sensation Disorders
GOUTMETALSAIN: Comparison of the Perception of Metallic Taste According to Lingual Locations in Healthy Volunteers
This is a mono center , observational study carried out within otorhinolaryngology department in CH Valence. This is a descriptive and exploratory study in healthy volunteers.
- Conditions
- Taste Disorders, Sensation Disorders, Taste, Metallic, Taste Disorder, Glossopharyngeal Nerve
- Trial name
- NCT05227157
- Testing
- swab with iron sulfate solution
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Valence
Obesity
Acute Effect of Animal and Vegetable Protein Rich Meals With Comparable Dietary Fibers Content on Appetite Sensation and Energy Intake
Background: New Nordic diet guidelines advocate a reduction in consumption of protein from animal sources such as beef and pork, due to environmental concerns.
- Trial name
- PAVA-II (NCT01616251)
- Testing
- Acute effect of animal and vegetable protein rich meals with comparable dietary fibers content on appetite sensation and energy intake
- Where
- Denmark
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Adverse Reaction to Diagnostic Agents and Kits Nos
Tracking Peripheral Blood Mononuclear Cells With Fluorine MRI
Cell-based therapies in the form of stem cell-based or immune cell-based therapies are becoming important treatment options that are either approved for clinical use or are showing promise in clinical trials.
- Trial name
- TRACK (NCT02921373)
- Testing
- 19F Cell Sense-labeled PBMC, MRI
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Gregory A. Dekaban
Visual Disorder
Clinical Evaluation of Approved and Investigational Contact Lenses
This study is a multi-site, 5-visit dispensing, bilateral double-arm parallel group design, double-masked clinical trial using an investigational contact lens and a marketed contact lens.
- Trial name
- NCT02669095
- Testing
- Investigational Contact Lenses (Test), Marketed Contact Lenses (Control)
- Where
- 4 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Aging, Hearing Loss
Working Memory Changes With Aging and Hearing Loss
Hearing loss is one of the most common health concerns affecting 1 in 3 Americans over 60 years of age rising to 1 in 2 for those over 85 years old.
- Trial name
- NCT01253031
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Quality of Life, Cancer
Impact on Quality of Life of Long-term Ototoxicity in Cancer Survivors
This project aims to explore, in depth, the burden of hearing loss and tinnitus on cancer survivors. Using semi-structured interviews, audiograms and a variety of validated questionnaires, the specific impact ototoxicity has on…
- Conditions
- Quality of Life, Cancer, Hearing Loss, Sensorineural, Tinnitus, Subjective
- Trial name
- NCT04281953
- Testing
- High frequency audiometry, Short-Form 36-Item Questionnaire (SF-36), Hearing handicap inventory for adults/elderly (HHIA/HHIE)
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Amblyopia
Perceptual Learning Treatment for Amblyopia
Objectives. To develop a new treatment for amblyopia using a perceptual learning approach. Hypothesis to be tested. Our proposed experiments are designed to investigate whether practicing a grating detection task can improve…
- Trial name
- NCT03788031
- Testing
- Acuity training, Occlusion therapy
- Where
- Hong Kong
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Total Knee Arthroplasty
Effection of Total Knee Arthroplasty on Knee Joint
The aim of this study is to evaluate the joint position sense of individuals diagnosed with knee osteoarthritis and who have undergone unilateral total knee arthroplasty surgery, and to examine the effect of joint position sense…
- Trial name
- NCT05965765
- Testing
- Total knee arthroplasty, osteoarthritis without surgery, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- KTO Karatay University
Assessment of Vascular Health Risk Factors
Innsbruck Health Promotion Program
The primary goal of this single-centre. single-arm, unblinded, pre-post interventional study is to evaluate whether a one-time health assessment and intervention affects the overall vascular health evaluated through the Life's…
- Trial name
- INNHEALTH (NCT06813677)
- Testing
- In-person health promotion
- Where
- Austria
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- VASCage GmbH
Hearing Loss, Sensorineural, Hearing Loss, Bilateral
iotaSOFT Pediatric Study
Prospective, non-randomized, open-label study to evaluate the safety and efficacy of the iotaSOFT Insertion System when used to assist electrode array insertion during cochlear implant surgery in a pediatric population.
- Conditions
- Hearing Loss, Sensorineural, Hearing Loss, Bilateral, Hearing Loss, Unilateral
- Trial name
- NCT06106373
- Testing
- iotaSOFT Insertion System
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- iotaMotion, Inc.
Anxiety Disorders and Symptoms, Sensory Disorders
Assessing the Clinical Utility of tACS
The present study seeks to evaluate the clinical utility of repeated transcranial alternating current stimulation (tACS) by assessing long-term, lasting changes in oscillatory activity and subsequent changes in related behavioral…
- Conditions
- Anxiety Disorders and Symptoms, Sensory Disorders, Hypervigilance, Post Traumatic Stress Disorder
- Trial name
- NCT03305328
- Testing
- Transcranial Alternating Current Stimulation
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Florida State University
Hearing Loss, Sensorineural Hearing Loss
Study to Determine the Safety, Tolerability, and Pharmacokinetic Profile of HPN-07 and HPN-07 Plus NAC
This study is a single-center, randomized, placebo-controlled, double-blind, single ascending dose escalation study to determine the safety, tolerability, and PK profile of oral administration of HPN-07 in single doses to…
- Conditions
- Hearing Loss, Sensorineural Hearing Loss, Noise-Induced Hearing Loss
- Trial name
- NCT02259595
- Testing
- HPN-07, NAC
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Otologic Pharmaceutics, Inc.
Tinnitus
Tinnitus Sound Therapy Using Mobile Application.
Over the years Tinnitus Sound Therapy (TST) has been undergoing rigorous modification according to the availability of various technologies such as Hearing Aids, personal amplification devices, mp3 players, and now mobile phones.
- Trial name
- TST (NCT06104865)
- Testing
- Tinnitus Sound Therapy using (Resound Tinnitus relief) mobile application
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dr. Basel Samman
Healthy Adults Aged 50 and Over
BrainLive Connect: Volunteer Training Programme
The goal of this mixed method clinical trial is to evaluate whether BrainLive Coach training can enhance knowledge, skills, and wellbeing among young old volunteers.
- Trial name
- NCT07544875
- Testing
- BrainLive Coach training, Other intervention
- Where
- Hong Kong
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Eye Diseases
iSCREEN-study: Online Nurse-assisted Eye-screening in Home Healthcare
The aim of this study is to investigate the cost-effectiveness of a nurse-assisted online eye-screening in home healthcare in reducing eye complaints.
- Trial name
- NCT06058637
- Testing
- Eye screening
- Where
- Netherlands
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
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