Clinical trials: Sensory Function
Cycloplegia, Refractive Errors
Cycloplegic Refraction in Pediatric Patients With Esotropia
The primary outcome of this study is to compare cyclopentolate 1% and tropicamide 1% for cycloplegic refractions in pediatric populations with esotropia.
- Conditions
- Cycloplegia, Refractive Errors, Esotropia, Vision Disorders
- Trial name
- NCT06077682
- Testing
- Cyclopentolate, Tropicamide
- Where
- 2 sites in Jordan, Qatar
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Islamic Hospital, Jordan
Position Sense
Inclinometer Reliability in Seated Shoulder Position Sense Assessment
Inclinometer Assessment of Seated Shoulder Position Sense: Intra- and Inter-Rater Reliability and Validity
- Trial name
- NCT06875271
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Conductive Hearing Loss
Wideband Tympanometry as a Non-behavioral Test of the Speech-weighted Middle Ear Transfer Function.
There is a need for a non-behavioral clinical test that provides an assessment of how speech is conducted through the middle ear for the optimization of middle ear implants.
- Trial name
- NCT07557771
- Testing
- Wideband Tympanometry
- Where
- Belgium
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Cannabis, Pain
Impact of Repeatedly-Administered THC-cannabis on Experimental Pain and Abuse Liability in Humans
Chronic pain is a significant public health concern in the U.S., for which prescription opioids have historically been the standard treatment. This has resulted in striking rates of opioid use disorders and fatal overdoses.
- Conditions
- Cannabis, Pain, Tolerance, Hyperalgesia
- Trial name
- NCT04596644
- Testing
- Active Cannabis
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Spinal Cord Injuries (SCI)
A Comprehensive Assessment of Altered Embodiment in Individuals With Spinal Cord Injury
Spinal cord injury (SCI) occurs when trauma or other factors damage the spinal cord, disrupting the flow of sensory information from the body to the brain.
- Trial name
- SCI_Embodiment (NCT06688916)
- Testing
- Behavioral assessment, Functional Magnetic Resonance Imaging (fMRI)
- Where
- Switzerland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Swiss Paraplegic Research, Nottwil
Diet Habit, Diet Modification
Interaction of Salivary Proteins and Polyphenols
Participants will be chosen through an initial sensory test to find high and low-perceivers of astringency. Selected participants will drink a chocolate milk or milk substitute beverage for one week each with washout weeks in…
- Conditions
- Diet Habit, Diet Modification, Taste, Altered, Saliva Altered
- Trial name
- NCT03501238
- Testing
- Chocolate Milk, Chocolate milk substitute, Chocolate milk substitute with gelatin
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Purdue University
Noise-Induced Hearing Loss, Hearing Protection Device Use
Comparative Efficacy of Earplug Usage Instruction
The goal of this clinical trial is to learn whether video-based training or paper-based training is more effective at teaching correct earplug insertion technique, in hospital personnel at Maharaj Nakorn Chiang Mai Hospital who…
- Conditions
- Noise-Induced Hearing Loss, Hearing Protection Device Use, Noise-exposed Hospital Personnel
- Trial name
- CEEUIn (NCT07731321)
- Testing
- Video-Based Earplug Instruction, Paper-Based Earplug Instruction
- Where
- Thailand
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Sirinthorn Chanaveroj
Hearing Loss, Sensorineural
PC-Based Rehabilitation of Auditory Function
Many older subjects experience difficulty in understanding speech in noisy environments. Part of this problem is related to changes that occur in the ear with age and compromise the hearing of high-pitched sounds.
- Trial name
- CINT (NCT00724347)
- Testing
- Consonant Identification Training
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Complex Regional Pain Syndrome, Peripheral Nerve Injuries
Somatosensory Assessment and Rehabilitation of Allodynia (SARA)
This pilot study will test a new therapy, somatosensory rehabilitation, for the painful sensitivity experienced by persons with nerve injuries and/or complex regional pain syndrome (CRPS).
- Conditions
- Complex Regional Pain Syndrome, Peripheral Nerve Injuries, Hand Fractures
- Trial name
- SARA (NCT02070367)
- Testing
- Somatosensory rehabilitation, Usual treatment: physiotherapy
- Where
- Canada
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Tinnitus
The Effect of Tinnitus Retraining Therapy on Subjective and Objective Measures of Chronic Tinnitus
The objective of this study is to examine the efficacy of tinnitus retraining therapy (TRT) as a treatment of chronic tinnitus in people with limited hearing loss.
- Trial name
- NCT00124800
- Testing
- Tinnitus retraining therapy, Sound therapy
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Tinnitus Research Consortium
Hearing Loss
Randomised Study of Web-Based Auditory Training With Varying Perceptual and Cognitive Demands on Training Gains and Generalised Speech, Cognitive, and Communication Outcomes
WP1: PLUS-Auditory Training The goal of this experimental study is to better understand how task difficulty affects on-task learning thresholds and generalised benefits in two PLUS auditory training tasks involving perceptual and…
- Trial name
- PLUS-Optimal (NCT07506408)
- Testing
- Practice Listening and Understand Speech (PLUS)
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Tinnitus, Neuroinflammation
Tinnitus and Treatment With umPEA-LUT
Tinnitus can have different causes. From a peripheral point of view, the sensation of hearing a not present sound can be indicative of damage in the cells of the cochlea.
- Trial name
- TiniPEA (NCT06718452)
- Testing
- PEA-LUT 2 sachet day, umPEALUT + Rutin + 5 hTp
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Campania Luigi Vanvitelli
Central Visual Impairment
Training Oculo-motor Control to Improve Vision When Using a Preferred Retinal Locus
When high-detail vision is lost due to a retinal disease such as macular degeneration, people see poorly, and have difficulty with eye movements (oculo-motor control).
- Trial name
- NCT05637385
- Testing
- Training of perception and oculo-motor control
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Russell L. Woods
Sensory Loss (Impairment of Sight and/or Hearing)
In It Together: Using Acceptance and Commitment Therapy to Treat Distress Among Older Adults With Sensory Loss and Their Spouses
Impairments in hearing and/or vision are common in older age. Having lived one's life as a fully sighted and hearing individual, older adults with sensory loss must come to terms with their declining capacity to interact with…
- Trial name
- SoS (NCT04781608)
- Testing
- English: In It Together (IIT)
- Where
- Denmark
- Volunteers
- 662 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Hearing Loss, Noise-Induced
Noise Exposure and Near-Infrared Light
The primary objective of this work is to determine the effect noise has on the auditory system (both auditory health and performance) and also the degree to which the effect of pre-noise therapy such as Near Infrared (NIR) light…
- Trial name
- NCT03834714
- Testing
- Near Infrared Light, Noise Stimulus
- Where
- 3 sites in United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Miami
Cancer
Sensory Approach of Food Modifications Led by Chemotherapy
The aim of the present study was to evaluate the impact of chemotherapy on sensorial perception in lung cancer patients in comparison to a control group (individuals without lung cancer and chemotherapy treatment).
- Trial name
- ARC-1 (NCT02368509)
- Testing
- Perform sensory tests
- Where
- 3 sites in France
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Hyperalgesia
The Effect of High-dose Remifentanil on Established Capsaicin-induced Hyperalgesia in Human Volunteers
Treatment of chronic pain is a major clinical challenge since chronic pain is frequent and leads to deterioration of quality of life.
- Trial name
- RemiAnes 1 (NCT00886106)
- Testing
- Remifentanil, Midazolam
- Where
- Austria
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Amputation
Virtual Neuroprosthesis: Restoring a Sense of Touch to Amputees
The overall goal of this project is to develop a virtual neuroprosthesis in which a facsimile of a neural implant is externalized and housed in a well-controlled microfluidic chamber, thereby abating the intrinsic limitations of…
- Trial name
- NCT03581448
- Testing
- Sensory Restoration During Prosthesis Control
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Florida Atlantic University
Pain, Hyperalgesia
Effect of Valdecoxib Pretreatment on Pain and Secondary Hyperalgesia in Healthy Volunteers
Tis study was designed to test the hypothesis that pretreatment with valdecoxib, prior to injury could reduce or prevent the development of secondary hyperalgesia around the area of primary injury.
- Trial name
- NCT00260325
- Testing
- valdecoxib
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Penn State University
COVID-19
Diagnostic Value of Patient - Reported and Clinically Verified Olfactory Disorders (COVID-19)
Participants are healthcare workers and adult outpatients referred in a COVID-19 screening center. Patients-reported symptoms are collected, then participants underwent a simple olfactory test (CODA for Clinical Olfactory…
- Trial name
- COVID-OLFA (NCT04407494)
- Testing
- Reporting of anosmia, ageusia and other clinical symptoms
- Where
- France
- Volunteers
- 809 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
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