Clinical trials: Sensory Function
Deafness, Hearing Loss
Children's Bilateral Cochlear Implantation in Finland
The purpose of this study is to evaluate short and long term outcomes (benefits and side-effects) of bilateral cochlear implantation and bilateral hearing aid rehabilitation in Finnish children.
- Trial name
- FinBiCI (NCT00960102)
- Testing
- cochlear implant, hearing aid
- Where
- 5 sites in Finland
- Volunteers
- 40 people
- Sponsor
- Kuopio University Hospital
Hemophilia a, Muscle Strength
Effect of Kinetic Chain Exercises on Muscle Strength, Joint Position Sense and Quality of Life in Children with Haemophilia.
The goal of this clinical trial is to learn if there are effect of close kinetic chain exercises on muscle strength, joint position sense and Quality of life in children with haemophilia? Null hypothesis It will be hypothesized…
- Conditions
- Hemophilia a, Muscle Strength, Joint Position Sense, Quality of Life (QOL)
- Trial name
- NCT06649175
- Testing
- Exercise
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Congenital Deafness, Suspicion of Congenital Deafness
NGS Assessment of Congenitally Deafned Children and Neonatal Deafness Screnning
To assess the diagnostic value of NGS screnning in prelingually deafned children using a new designed chip, and to evaluate its interest in a the neonatal screening program for ddetecting congenitally deafned children.
- Trial name
- GHELP (NCT04350619)
- Testing
- Genetic screening. No therapeutic intervention
- Where
- France
- Volunteers
- 220 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Age-related Macular Degeneration, Aging
Functionally Validated Structural Endpoints for Early AMD
Delayed rod-mediated dark adaptation (RMDA), or delayed recovery of vision in a dark environment, is a functional biomarker (i.e., risk factor) for early age-related macular degeneration (AMD).
- Trial name
- ALSTAR2 (NCT04112667)
- Testing
- Normal Macular Health, Early Macular Degeneration, Young Normals
- Where
- United States
- Volunteers
- 556 people, healthy volunteers welcome
- Sponsor
- Cynthia Owsley
Healthy Subjects
Effect of High-dose Target-controlled Naloxone Infusion on Pain and Hyperalgesia During a Burn Injury
In several rodent studies, it has been demonstrated that very high doses of opioid antagonists (i.e., naloxone 3-10 mg/kg) administered after weeks after recovery from an inflammatory injury may lead to a reinstatement of…
- Trial name
- TCI-NX-BI (NCT02684669)
- Testing
- Naloxone, Normal saline
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- mads u werner
Hearing Loss
Cochlear Implant Low Power Strategy
Reducing power consumption in the cochlear implant is crucial to the development of future smaller sound processors. The commercial MP3000 sound coding strategy has been shown to be more efficient in power consumption to the…
- Trial name
- NCT02879539
- Testing
- MP3000 sound coding strategy or ACE strategy with lower stimulation
- Where
- Australia
- Volunteers
- 32 people
- Sponsor
- The Hearing Cooperative Research Centre
Hearing Loss
Self-monitoring of Hearing Aids Using Artificial Intelligence
This project investigates how self-monitoring of hearing aids through an AI-based mobile app can complement physical and digital healthcare visits.
- Trial name
- NCT07255586
- Testing
- Self-monitoring of hearing aids using artificial intelligence, Traditional hearing care at our clinics.
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Sodra Alvsborgs Hospital
Parkinson´s Disease
Olfaction in Patients With Parkinson's Disease Following Treatment With Rasagiline
There is convincing evidence from numerous studies using both psychophysical and electrophysiological approaches that olfaction is markedly reduced in Parkinson´s disease (PD).
- Trial name
- NCT00902941
- Testing
- Azilect 1mg
- Where
- Germany
- Volunteers
- 34 people
- Sponsor
- Technische Universität Dresden
Obesity
Auditory Sensory Attenuation in Obesity
The goal of this observational cross-sectional study is to test the sensory attenuation effect with auditory stimuli comparing women with obesity and healthy-weight women.
- Trial name
- Ud_SA_OB (NCT06298539)
- Where
- Italy
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Istituto Auxologico Italiano
Retinitis Pigmentosa, Usher Syndrome Type 2
Study to Evaluate Safety and Tolerability of QR-421a in Subjects With RP Due to Mutations in Exon 13 of the USH2A Gene
The purpose of this study is to evaluate the safety and tolerability of QR-421a administered via intravitreal injection (IVT) in subjects with Retinitis Pigmentosa (RP) due to mutations in exon 13 of the USH2A gene.
- Conditions
- Retinitis Pigmentosa, Usher Syndrome Type 2, Deaf Blind, Retinal Disease
- Trial name
- Stellar (NCT03780257)
- Testing
- QR-421a
- Where
- 7 sites in United States, Canada and 1 more
- Volunteers
- 20 people
- Sponsor
- ProQR Therapeutics
Viral Respiratory Tract Infection, Influenza
Use of Wearable Sensors for Early Detection and Tracking of Viral Respiratory Tract Infections
Viral respiratory tract infections (VRTI) are among the most common human illnesses, impacting billions globally. There is an unmet need to identify novel ways to detect, treat and prevent their spread.
- Trial name
- WE SENSE (NCT05290792)
- Testing
- Administration of FluMist (Live Attenuated Influenza Vaccine)
- Where
- Canada
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Emily McDonald
Hearing Loss
A System and Process to Improve the Satisfaction With Hearing Health Products
Innovative Design Labs Inc. (IDL) and its collaborators, proposes to create a cloud-based system which integrates advances and techniques from Health and Wellness Coaching (HWC) into the Hearing Aid (HA) fitting and trial process.
- Trial name
- NCT04926636
- Testing
- Health and Wellness Coaching
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Minnesota
Orthopedic Disorder, Arthropathy of Knee
Total Knee Arthroplasty and Clinical Findings
Knee osteoarthritis is a common disease that causes pain and loss of function. Total Knee Arthroplasty (TKA) is a frequently used surgical method in the treatment of severe knee osteoarthritis.
- Conditions
- Orthopedic Disorder, Arthropathy of Knee, Pain, Joint, Proprioception
- Trial name
- NCT04481711
- Testing
- Total Knee Arthroplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Karadeniz Technical University
Taste Disorders, Sensation Disorders
GOUTMETALSAIN: Comparison of the Perception of Metallic Taste According to Lingual Locations in Healthy Volunteers
This is a mono center , observational study carried out within otorhinolaryngology department in CH Valence. This is a descriptive and exploratory study in healthy volunteers.
- Conditions
- Taste Disorders, Sensation Disorders, Taste, Metallic, Taste Disorder, Glossopharyngeal Nerve
- Trial name
- NCT05227157
- Testing
- swab with iron sulfate solution
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Valence
To Better Understand How Epicenter's (Which House Education, Health and Finance Centers in Ghana) Increase Individual's Sense of Empowerment.
Evaluating the Hunger Project in Ghana
The Hunger Project/Epicenter strategy is a community based development strategy that will positively affect health, education, empowerment, and consumption.
- Trial name
- NCT00532753
- Testing
- Community Empowerment
- Where
- Ghana
- Volunteers
- 20,000 people
- Sponsor
- University of California, Berkeley
Anterior Knee Pain Syndrome, Proprioceptive Disorders
Joint Position Sense in Individuals With Anterior Knee Pain
Introduction Anterior knee pain (AKP) commonly affects physically active as well as sedentary individuals and the aetiology remains unknown.
- Trial name
- NCT03998241
- Testing
- No intervention was provided
- Where
- South Africa
- Volunteers
- 25 people
- Sponsor
- University of Stellenbosch
Prader-Willi Syndrome
Home-based SSP on Individuals With PWS
The Polyvagal Theory focuses on how function and structure changed in the vertebrate autonomic nervous system during evolution. The theory is named for the vagus, a major cranial nerve that regulates bodily state.
- Trial name
- NCT03871751
- Testing
- Safe and Sound Protocol
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Indiana University
Obesity
Acute Effect of Animal and Vegetable Protein Rich Meals With Comparable Dietary Fibers Content on Appetite Sensation and Energy Intake
Background: New Nordic diet guidelines advocate a reduction in consumption of protein from animal sources such as beef and pork, due to environmental concerns.
- Trial name
- PAVA-II (NCT01616251)
- Testing
- Acute effect of animal and vegetable protein rich meals with comparable dietary fibers content on appetite sensation and energy intake
- Where
- Denmark
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Adverse Reaction to Diagnostic Agents and Kits Nos
Tracking Peripheral Blood Mononuclear Cells With Fluorine MRI
Cell-based therapies in the form of stem cell-based or immune cell-based therapies are becoming important treatment options that are either approved for clinical use or are showing promise in clinical trials.
- Trial name
- TRACK (NCT02921373)
- Testing
- 19F Cell Sense-labeled PBMC, MRI
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Gregory A. Dekaban
Hearing Loss, Bilateral or Unilateral, Hearing Loss, Conductive
Sentio Systematic Evaluation
The study is designed as an international, multi-center, single-armed, non-interventional/observational study including subjects who has received or are planned to receive the Sentio system as part of normal clinical practice.
- Conditions
- Hearing Loss, Bilateral or Unilateral, Hearing Loss, Conductive, Hearing Loss, Mixed Conductive-Sensorineural, Single Sided Deafness
- Trial name
- SENSE (NCT07161154)
- Testing
- Transcutaneous bone conduction hearing system
- Volunteers
- 100 people
- Sponsor
- Oticon Medical
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