Clinical trials: Sentinel Lymph Node Detection
Endometrial Neoplasms
Indocyanine Green Versus Blue Dye for Detection of Sentinel Lymph Node In Endometrial Cancer
To determine the difference in the proportion of hemipelves with successful detection of Sentinel Lymph Node according to the dye used (indocyanine green with near-infrared imaging vs blue dye) in women with endometrial cancer.
- Trial name
- NCT02564276
- Testing
- Sentinel lymph node biopsy
- Where
- Canada
- Volunteers
- 132 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Lymphedema, Breast Cancer
Arm Circumference Measurement With or Without Bioimpedance Spectroscopy in Finding Lymphedema Early in Patients With Stage I-III Breast Cancer
This randomized pilot clinical trial studies arm circumference measurement with or without bioimpedance spectroscopy in finding extra lymph node fluid build up in the arm (lymphedema) early in patients with stage I-III breast…
- Trial name
- NCT03648983
- Testing
- arm circumference measurement, Bioimpedance spectroscopy
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Albert Einstein College of Medicine
Vulvar Cancer
Study of Near-Infrared Imaging With Indocyanine Green for Detection of Sentinel Lymph Nodes in People With Vulvar Cancer
The purpose of this study is to compare two types of imaging for sentinel lymph node (SLN) mapping in people with early-stage vulvar cancer.
- Trial name
- NCT06127836
- Testing
- ICG guided sentinel lymph node biopsy
- Where
- 8 sites in United States
- Volunteers
- 22 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Sentinel Lymph Node Biopsy
Sentinel Node Detection in Cervical Cancer
Evaluation of sensitivity of Sentinel lymph nodes for detecting nodal metastases in cervical cancer
- Trial name
- SLNcxca (NCT03680833)
- Testing
- Sentinel node detection in cervical cancer
- Where
- Sweden
- Volunteers
- 226 people
- Sponsor
- Region Skane
Endometrial Cancer, Sentinel Lymph Node
Cervical and Endometrial Injection for Sentinel Lymph Node Detection in Endometrial Cancer
The investigators think that trans-cervical endometrial tracer injection will cause more paraaortic sentinel lymph node detection. Also, this application is easy, cost-effective and safer than hysteroscopic method.
- Trial name
- NCT03900104
- Testing
- Transcervical endometrial injection of technetium 99 m-labeled human albumin colloid particles, Cervical injection of technetium 99 m-labeled human albumin colloid particles
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Kocaeli University
Endometrial Cancer
Pelvic Sentinel Node Detection Using Indocyanine Green Learning Curve
According to ESGO-ESTRO-ESMO guidelines, pelvic Sentinel lymph node detection is suitable for lymph node staging in endometrial carcinoma of the uteri.
- Trial name
- ENDO-GREEN (NCT04958278)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Brest
Breast Carcinoma, Breast Carcinoma Metastatic in Lymph Node
Magseed and Magtrace Localization for Breast Cancer
The aim of this study is to compare the efficacy of the Sentimag localization system and its tracer Magtrace, superparamagnetic iron oxide nanoparticles, as a tracer in sentinel node biopsy in breast cancer with Tc99 in a…
- Trial name
- NCT05161507
- Testing
- Magseed, Magtrace, Axillary lymph node metastasis - needle biopsy
- Where
- Czechia
- Volunteers
- 70 people
- Sponsor
- University Hospital Ostrava
Cervical Cancer
Sentinel Lymph Node Detection in Early Cervical Cancer
The primary objective of this study is to determine the feasibility of detecting the sentinel lymph node (SLN) in patients with early invasive cervical cancer using a combined radioisotope and blue dye technique.
- Trial name
- NCT02543775
- Testing
- Preoperative and intraoperative SLN Mapping
- Where
- Canada
- Volunteers
- 75 people
- Sponsor
- University Health Network, Toronto
Gastric Cancer (GC), Sentinel Lymph Node Biopsy (SLNB)
Sentinel Lymph Node Detection in Gastric Cancer Using a Dual Tracer (Superparamagnetic Iron Oxide and Methylene Blue): A Prospective Study With Histological and OSNA Validation
Gastric cancer (GC) remains an oncological challenge, where lymph node involvement is a key prognostic factor. Sentinel lymph node (SLN) mapping may improve staging and reduce surgical morbidity.
- Trial name
- SLN_GC_SPIO (NCT07147452)
- Testing
- Dual tracer: The infiltration of the Supermagnetic Iron Oxide (SPIO) and Methylene Blue, OSNA AND H-E
- Where
- Spain
- Volunteers
- 44 people
- Sponsor
- Hospital del SAS de Jerez
Breast Cancer Invasive
Intra-operative Detection of Positive Margins and Lymph Nodes in Breast Surgery
In this project, the investigators will develop novel optical coherence tomography (OCT)-Raman spectroscopy and autofluorescence (AF)-Raman spectroscopy systems based on a selective sampling approach optimised for high-resolution…
- Trial name
- NCT06977698
- Testing
- OCT-Raman, AF-Raman
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- University of Nottingham
Endometrial Cancer
Sentinel Node in Endometrial Cancer
Phase II, open-label, randomized pilot study. Patients will be randomized (1:1) to receive for sentinel node screening: 1. Radiotracer (RT) via cervical administration and TUMIR 2.
- Trial name
- HYBRIDENDONOD (NCT04492995)
- Testing
- injection via TUMIR of the tracer [99mTc] Tc-albumin nanocoloid-ICG (6 mCi, 4 ml), injection via TUMIR of [99mTc] Tc-albumin nanocoloid (6mCi, 8ml).
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- Judit Pich Martínez
Endometrial Cancer, Endometrial Neoplasms
Real-time Lymphatic Channel Visualization Improves Bilateral Sentinel Lymph Node Detection in Endometrial Cancer
Endometrial cancer is the most common malignancy of the female genital tract. Standard treatment for early-stage disease includes hysterectomy, bilateral salpingo-oophorectomy, and lymph node assessment.
- Conditions
- Endometrial Cancer, Endometrial Neoplasms, Sentinel Lymph Node Biopsy (SLNB)
- Trial name
- NCT05191212
- Testing
- indocyanine green
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Colon Cancer, Colon Surgery
Indocyanine Green (ICG) in the ex Vivo Detection of Sentinel Lymph Node (SLN)in Colon Cancer
Evaluation of the possibility to detect sentinel lymph node(s) after ex vivo Indocyanine Green injections around the tumour in pieces of colectomy from patients with colon cancer.
- Trial name
- 2068 (NCT01995591)
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Jules Bordet Institute
Endometrial Carcinoma
Improved Method of Detecting Cancer Metastases
The purpose of this study is to compare the Instillation Technique Using The Modified Intra- Uterine Manipulator Catheter With Methylene Blue, Isosulfan Blue or Indocyanine Green Dyes, Compared to Cervical Injection, For Sentinel…
- Trial name
- SITs (NCT02368067)
- Testing
- Standard of Care Sentinal Node Dye, Study Sentinal Node Dye
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Southeastern Regional Medical Center
Breast Cancer, Sentinel Lymph Node Biopsy (SLNB)
Implementation of Indocyanine Green to Identify Sentinel Lymph Nodes During Surgery for Breast Cancer
The goal of this clinical trial is to learn how to successfully introduce a new method for finding the sentinel lymph node during breast cancer surgery into routine hospital care.
- Conditions
- Breast Cancer, Sentinel Lymph Node Biopsy (SLNB), Sentinel Lymph Node Detection, Sentinel Lymph Node
- Trial name
- INFINITE (NCT07146295)
- Testing
- Technetium (99mTc), Indocyanine Green, Sentinel lymph node biopsy
- Where
- 7 sites in Netherlands
- Volunteers
- 1,760 people
- Sponsor
- Isabelle Henskens
Cervical Cancer
TMVP1-ICG Mapping in Laparoscopic SLN Detection in Cervical Cancer
Sentinel lymph node (SLN) mapping is an acceptable surgical strategy determine whether to perform radical lymphadenectomy in patients with early-stage cervical cancer.
- Trial name
- NCT03320772
- Testing
- TMVP1-ICG, ICG
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Huazhong University of Science and Technology
Endometrial Cancer
Concurrent Use Lymphoseek & Indocyanine Green in Sentinel Lymph Node Detection in Endometrial Cancer
The goal of this study is to (i) improve detection of sentinel nodes and (ii) reduce additional surgical dissection that is needed in case a sentinel lymph node cannot be detected.
- Trial name
- NCT04511026
- Testing
- Lymphoseek, Single Photon Emission Computed Tomography (SPECT), Indocyanine Green (ICG)
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Stanford University
Prostatic Neoplasms
Sentinel Lymph Node Detection in Prostate Surgery by Laparoscopy
In this study the investigators want to determine if the detection of lymph node is applicable in prostatectomy by laparoscopy.
- Trial name
- NCT01296217
- Testing
- lymph nod detection
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Centre René Gauducheau
Sentinel Lymph Node, Breast Cancer
A Clinical Feasibility Study of a Photoacoustic Finder
Determining the prognosis of breast cancer relies significantly on axillary staging by sentinel lymph node biopsy (SLNb). The SLNb is generally performed using radioisotopes, blue dyes, or both to improve the false negative rate.
- Trial name
- NCT06412211
- Testing
- Photoacoustic finder
- Where
- South Korea
- Volunteers
- 129 people
- Sponsor
- Seoul St. Mary's Hospital
Uterine Cervical Neoplasms, Uterine Neoplasms
Early Feasibility Study of the "Easy Light" Fluorecence Imaging System
This is an early feasibility study to evaluate the device functionality of an open-field handheld wireless fluorecence imaging system for detection of sentinel lymph nodes in women with cervical and uterine cancers who underwent…
- Trial name
- NCT05004623
- Testing
- Sentinel Lymph Node Biopsy
- Where
- Brazil
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Professor Fernando Figueira Integral Medicine Institute