Clinical trials: Sequelae
Stroke Sequelae, Cognitive Impairment
Remote Bimanual Virtual Rehabilitation Post CVD
The aim of the study is to develop the BrightBrainer G (grasp), a game-based upper-extremity motor and cognitive rehabilitation system using custom virtual reality simulations.
- Conditions
- Stroke Sequelae, Cognitive Impairment, Depression
- Trial name
- NCT04713384
- Testing
- Integrative tele-rehalitation of chronic stroke survivors using custom therapeutic games
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Grigore Burdea
Stroke, Stroke Sequelae
Noninvasive VNS to Facilitate Excitability in Motor Cortex
Transcranial Magnetic Stimulation (TMS) positively influences motor rehabilitation in stroke recovery. Transcutaneous auricular vagus nerve stimulation (taVNS) has shown effects on cortical plasticity.
- Conditions
- Stroke, Stroke Sequelae, Motor Activity
- Trial name
- NCT04130646
- Testing
- Transcranial Magnetic Stimulation, transcutaneous auricular vagus nerve stimulation (taVNS)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Weight Loss
The Outcome of Abdominoplasty After Massive Weight Loss
The primary aim of this study is to compare early surgical complications after abdominoplasty performed by plastic and general surgeons.
- Trial name
- NCT02679391
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Stroke Sequelae
Mobile and Interactive Robot's Social Acceptability for Balance and Gait Rehabilitation
The recovery of a balance and gait is a primary objective for geriatric, neurological or orthopedic rehabilitation. Since the 80s, many walking robots were proposed.
- Trial name
- ROBO-K (NCT03651960)
- Testing
- ROBOT PROTOTYPE
- Where
- France
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
SARS-CoV2 Infection
Qualitative and Functional Investigation of Lipids in Patients With SARS-CoV2 Infection - In Search of Atherogenic Sequelae
Currently, the world is facing a SARS-CoV2 coronavirus epidemic, which is responsible for COVID-19. In France, this virus has already infected several million people and is responsible for the death of more than 127,000.
- Trial name
- COVI-LIPI-D (NCT05476224)
- Testing
- Blood sample of 30 ml
- Where
- France
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Post-Acute COVID-19, Post Acute COVID-19 Syndrome
Safety and Dosage of a Computerized Cognitive Training Program for Cognitive Dysfunction After COVID-19
The goal of this Phase I/II clinical trial is to assess the safety and maximum tolerated training time of a self-administered computerized cognitive training (CCT) in individuals with cognitive dysfunction as a consequence of…
- Conditions
- Post-Acute COVID-19, Post Acute COVID-19 Syndrome, Cognitive Dysfunction, Cognitive Impairment
- Trial name
- CCTLongCOVID (NCT05582603)
- Testing
- CCT Long COVID
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidad Antonio de Nebrija
Brain Tumors
Working Memory Performance Among Childhood Brain Tumor Survivors
Children treated with radiation therapy for brain tumors are at risk for cognitive problems. These problems have typically been demonstrated on global cognitive measures including measures of intellectual functioning (IQ).
- Trial name
- NCT00693914
- Testing
- Series of tests/questionnaires
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital
Traumatic Brain Injury, Parkinson's Disease
Imaging Biomarkers of Delayed Sequelae in Trauma Brain Injury
The purpose of this study is to learn if a new brain imaging technology called DaTscan can detect subtle changes in the brain that are similar to those seen in early Parkinson's disease (PD).
- Trial name
- NCT01516281
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Prostate Cancer
Sexual and Urological Rehabilitation to Men Operated for Prostate Cancer and Their Partners
Today prostate cancer (PC) treatment with curative intent is primarily surgical removal of the prostate gland (prostatectomy) which may be associated with immediate and long lasting erectile dysfunction and decline in urinary…
- Trial name
- PROCAN (NCT02103088)
- Testing
- Sexual and urological intervention
- Where
- Denmark
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Danish Cancer Society
Sarcoma, Ewing's
Functional and Clinical Long-Term Outcome of Ewing Sarcoma Treatment
The purpose of the study is to assess the functional outcome, quality of life and late sequelae in a representative sample of 600 long-term survivors of Ewing sarcoma and to build a unique clinical and functional data pool of the…
- Trial name
- NCT00824083
- Where
- 2 sites in Germany
- Volunteers
- 950 people, healthy volunteers welcome
- Sponsor
- University Hospital Muenster
Stroke Sequelae, Motor Imagery
Decoding Motor Imagery From Non-invasive Brain Recordings as a Prerequisite for Innovative Motor Rehabilitation Therapies
Seminal studies in motor neuroscience involving healthy subjects have revealed time-locked changes in induced power within specific frequency bands.
- Conditions
- Stroke Sequelae, Motor Imagery, Upper Limb Deficit
- Trial name
- MODECO (NCT06469463)
- Testing
- MRI, MEG, EEG
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Traumatic Brain Injury, Fatigue
Brain and Gut Plasticity in Mild TBI or Post-acute COVID Syndrome Following Growth Hormone Therapy
Patients with a history of mild traumatic brain injury (mTBI) or post acute sequelae of SARS-CoV-2 (PASC) and abnormal growth hormone secretion, as measured by glucagon stimulation test, will be treated with replacement growth…
- Conditions
- Traumatic Brain Injury, Fatigue, Cognitive Impairment, COVID-19
- Trial name
- NCT03554265
- Testing
- Somatropin
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Covid19, Cardiac Disease
COvid-19 LongitUdinal Multiethnic BioImaging Assessment of CARDiovascular Sequelae Registry
COLUMBIA CARDS is a pilot study to understand how COVID-19 affects the heart. It is known that COVID-19 can affect the heart in different ways.
- Conditions
- Covid19, Cardiac Disease, Cardiac Arrhythmia, Myocarditis
- Trial name
- NCT04661657
- Testing
- Transthoracic echocardiogram (TTE), Cardiovascular Magnetic Resonance (CMR) Imaging
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Columbia University
Post-Acute COVID-19, Post COVID-19 Condition
Ventilatory and Perfusion Abnormalities in Individuals With Post-Acute Sequelae of SARS-CoV-2 Infection
Prospective cohort study to evaluate the utility of quantitative CT analysis to assess ventilation and perfusion defects in patients with Post-acute Sequelae of SARS-CoV-2 (PASC) and functional limitations
- Conditions
- Post-Acute COVID-19, Post COVID-19 Condition, Post Viral Fatigue, Dyspnea
- Trial name
- PASC VQ (NCT05866952)
- Testing
- Computed Tomography of the Chest
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tufts Medical Center
PASC Post Acute Sequelae of COVID 19, Fatigue
Neural Mechanisms of Fatigue in Post-Acute Sequela of SARS-CoV-2
This proposal aims to understand the neurobiological mechanisms of fatigue in individuals with Post-Acute Sequelae of SARS-CoV-2 Infection (PASC).
- Trial name
- NCT07278388
- Testing
- Physical Fatigue
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
PASC Post Acute Sequelae of COVID-19
Multiparametric [18F]F-AraG Imaging in Post-Acute Sequelae of COVID-19 (PASC)
This study uses total-body [¹⁸F]F-AraG PET/CT imaging to investigate immune activation and vascular changes in individuals with post-acute sequelae of SARS-CoV-2 infection (PASC), also known as Long COVID.
- Trial name
- NCT07076862
- Testing
- A.1 - [¹⁸F]F-AraG PET/CT (90-min dynamic + 4-h static), A.2 - [¹⁸F]F-AraG PET/CT (60-min dynamic only), B.1 - [¹⁸F]F-AraG PET/CT (90-min dynamic + 4-h static)
- Where
- 2 sites in United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Late Effects of Cerebrovascular Accident
Main Idea Perception of Written Stories and in Pictures Among Impaired Right Hemisphere Patients
Main idea perception of written stories and in pictures among impaired right hemisphere patients Abstract The right hemisphere is considered to complement the language processing abilities of the opposite hemisphere; it is…
- Trial name
- stroke (NCT02897791)
- Testing
- written evaluations
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Respiratory Syncytial Virus (RSV)
Understanding RSV: Severe Disease and the Long Term Consequences
The study design is a case-control, sample based study. 275 cases (Group 1), infants <12 months old with RSV infection and 40 controls (Group 2), otherwise healthy infants <12 months old without RSV infection will be recruited.
- Trial name
- NCT03756766
- Testing
- RSV point of care testing
- Where
- 2 sites in United Kingdom
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Post-acute Sequelae of SARS-CoV-2 Infection
Cognitive-Sensorimotor Function in Long-COVID
Growing evidence indicates that many people who have chronic post-acute sequelae of SARS-CoV-2 infection (PASC) will experience ongoing neurological and musculoskeletal impairment that can affect gait and balance.
- Trial name
- NCT06850350
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Stroke, Stroke Sequelae
Neural Bases of Post-stroke Emotion Perception Disorders
This monocentric physiological study will evaluate the neural bases of visual recognition of emotions in stroke patients vs. healthy controls using MRI (functional and structural connectivity) and EEG.
- Conditions
- Stroke, Stroke Sequelae, Emotions
- Trial name
- STROKEM (NCT05595005)
- Where
- France
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille