Clinical trials: Serum Bilirubin
Jaundice
Grape Seed Powder and Vitamin C Supplementation for Liver Disease (Acquired Hepatic Jaundice)
Jaundice is a frequent medical problem that affects people of all ages. It is important to note that jaundice is not an actual sickness as such itself but rather a symptom of liver illness brought on by an increase in the…
- Trial name
- AHJ (NCT07575789)
- Testing
- Grape-C supplement
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- University of Lahore Hospital (ULH)
Genetics
A Genome-Wide Scan For Quantitative Trait Loci of Serum Bilirubin - A Framingham Study
Studies have shown that there is a significant association between serum bilirubin concentrations and risk of coronary artery disease (CAD).
- Trial name
- NCT00340509
- Where
- United States
- Volunteers
- 1,888 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Jaundice, Serum Bilirubin
A Study to Evaluate a New Jaundice Stick Test
This is an observational prospective study. The main purpose is to evaluate the stability of the Bilistick system in a humid and hot climate compared to the quantitative test for serum bilirubin (SBR) measurement currently used…
- Trial name
- Bilistick (NCT02926131)
- Testing
- Blood sampling
- Where
- Thailand
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Hyperbilirubinemia, Neonatal
Role of Serum (B/A) Ratio Compared to (TSB) for Early Prediction of Bilirubin-induced Neurological Dysfunction (BIND).
The aim of this study is to evaluate serum bilirubin/albumin (B/A) ratio compared to total serum bilirubin (TSB) for early prediction of bilirubin-induced neurological dysfunction (BIND).
- Trial name
- NCT06603753
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- alaa aboelhassan mohamed aboelhassan
Appendicitis
Diagnostic Accuracy of Serum Bilirubin in the Prediction of Perforated Appendicitis
Hyperbilirubinemia is reported to be a positive predictor in diagnosing perforated appendicitis. Therefore we analysed the diagnostic accuracy of serum bilirubin in discriminating between perforated and simple/no appendicitis.
- Trial name
- NCT01698099
- Where
- Germany
- Volunteers
- 500 people
- Sponsor
- University Hospital Tuebingen
Neonatal Jaundice
Efficacy of Zinc in Reducing Hyperbilirubinemia Among High Risk Neonates - A Double Blind Randomized Trial
The purpose of this study is to determine the effect of 10 mg of oral zinc given daily between days 2 and 7 of life to term or near term neonates with serum bilirubin levels of more than 6 mg/dL at 24 ± 6 hours of life on…
- Trial name
- NCT00692224
- Testing
- zinc gluconate
- Where
- India
- Volunteers
- 294 people
- Sponsor
- All India Institute of Medical Sciences
Normal Tension Glaucoma, Bilirubin; Defect, Excretion
Serum Bilirubin Levels in Normal-tension Glaucoma
Purpose: To analyze the relationship between normal-tension glaucoma (NTG) and serum bilirubin levels. Materials and Methods: This research included 38 patients with NTG and 38 healthy controls with similar age and sex…
- Trial name
- NCT03387306
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Trakya University
Jaundice, Deep Learning
A Prospective Study: Smart Phone Application for Measure Serum Bilirubin Through Sclera Images
The primary efficacy endpoints are the standard deviation and coefficient of determination (R2) between predicted and actual values for the bilirubin regression model, and the grading accuracy for the jaundice severity…
- Conditions
- Jaundice, Deep Learning, Hyperbilirubinemia, Sclera
- Trial name
- NCT06421844
- Where
- China
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Air Force Military Medical University, China
Procedural Pain in Newborns
Leg and Foot Massage for Pain in Newborns Receiving Heel Stick
This study aims to evaluate the effect of a leg and foot massage program on pain in newborns receiving heel stick for monitoring serum bilirubin levels.
- Trial name
- NCT07893028
- Testing
- Leg and Foot Massage
- Where
- Thailand
- Volunteers
- 42 people
- Sponsor
- Chulalongkorn University
Biliary Atresia
N-Acetylcysteine in Biliary Atresia After Kasai Portoenterostomy
Biliary atresia (BA) is a devastating liver disease of infancy, characterized by bile duct obstruction leading to liver fibrosis, cirrhosis, and eventual need for transplantation in most cases.
- Trial name
- NCT03499249
- Testing
- N-Acetyl cysteine
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Baylor College of Medicine
Neonatal Hyperbilirubinemia
Foot Reflexology and Massage in Neonates Receiving Phototherapy
Neonatal hyperbilirubinemia is a common condition in newborns and is frequently treated with phototherapy. In addition to standard treatment, non-pharmacological interventions such as massage and foot reflexology may help reduce…
- Trial name
- NCT07610811
- Testing
- Foot Reflexology, Body Massage, Phototherapy Device
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people
- Sponsor
- Aydin Adnan Menderes University
Jaundice, Neonatal
Comparison Of Fenofibrate Vs Phenobarbitone As Adjunct To Phototherapy In Reducing Total Serum Bilirubin In Indirect Hyperbilirubinemia In Neonates
This is a prospective, randomized, open-label controlled trial comparing fenofibrate (10 mg/kg) and phenobarbitone (3 mg/kg) as adjuncts to conventional phototherapy in neonates with unconjugated hyperbilirubinemia.
- Trial name
- NCT07774741
- Testing
- Fenofibrate + Phototherapy, Phenobarbitone + Phototherapy
- Volunteers
- 70 people
- Sponsor
- Rubab Fatima
Hyperbilirubinemia
Effect of Vitamin-D as an Adjuvant to Phototherapy in Reduction of Indirect Serum Bilirubin
The study aimed at filling the gaps by evaluating the effectiveness of vitamin-D as an adjuvant to phototherapy in reduction of indirect serum bilirubin among neonates with exaggerated physiological hyperbilirubinemia.
- Trial name
- NCT07098234
- Testing
- Vitamin D3, Phototherapy
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Muhammad Aamir Latif
Hyperbilirubinemia
Effect of Intravenous Fluid Supplementation on Serum Bilirubin and Cardiorespiratory Parameters in Preterm Infants During Phototherapy
The aim of the study was to evaluate the influence of a systematic extra intravenous fluid supplementation during phototherapy in comparison to a fluid supplementation due to short term demand in preterm infants.
- Trial name
- NCT01550627
- Testing
- extra fluid/iv fluid supplementation during phototherapy, Non extra fluid
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University of Jena
Hyper Bilirubinemia, Premature Infant
Cycled Phototherapy
Cycled phototherapy (PT) is likely to increase survival over that with continuous PT among extremely premature infants (< 750 g BW or <27 weeks GA).
- Trial name
- NCT03927833
- Testing
- Phototherapy lights
- Where
- 19 sites in United States
- Volunteers
- 1,700 people
- Sponsor
- NICHD Neonatal Research Network
Primary Biliary Cirrhosis
Umbilical Cord Mesenchymal Stem Cells for Patients With Primary Biliary Cirrhosis
Primary biliary cirrhosis (PBC) is a slowly progressive disease that causes substantial loss of intrahepatic bile ducts, ultimately resulting in cholestasis, advanced fibrosis, cirrhosis, liver failure and even hepatocellular…
- Trial name
- NCT01662973
- Testing
- conventional plus UC-MSC treatment
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Beijing 302 Hospital
Neonatal Hyperbilirubinemia
Accuracy of TcB Measurements During and After Phototherapy
This study aimed to assess the accuracy of transcutaneous bilirubin measurements in term and late-preterm infants undergoing phototherapy.
- Trial name
- NCT07080398
- Testing
- serum bilirubin level measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Biliary Atresia
Tolerability of Enteral NAC in Infants
Biliary atresia (BA) is a neonatal liver disease characterized by impaired bile flow and is the most common indication for pediatric liver transplantation.
- Trial name
- NCT06260566
- Testing
- N-Acetylcysteine
- Volunteers
- 12 people
- Sponsor
- Sanjiv Harpavat
Hyperbilirubinemia, Neonatal
Effect of Probiotic Lacobacillus Reuterii on Serum Bilirubin Levels in Preterm Infants
The goal of this clinical trial is to learn about the effect of probiotic Lactobacillus reuterii on the level of serum bilirubin in moderately and late preterm infants with birth weights 1000 grams to 2499 grams who were admitted…
- Trial name
- NCT06672406
- Testing
- Lactobacillus reuterii
- Where
- Indonesia
- Volunteers
- 40 people
- Sponsor
- Hasanuddin University
Hyperbilirubinemia, Neonatal
Transcutaneous Bilirubin Levels From Covered Skin
The aim of this study was to evaluate the levels of total serum bilirubin and transcutaneous bilirubin in newborns, measured in both covered and exposed areas, before phototherapy, 24th hour of phototherapy and 8 hours after…
- Trial name
- NCT06105879
- Testing
- covered or open skin
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Ankara Training and Research Hospital