Clinical trials: Serum Iron
Iron Overload
The Iron Content of Ferritin in Serum and Urine of Children With High Serum Ferritin Levels
A serum ferritin level can reflect the total body iron content, thus a very low serum ferritin is commonly used as an indicator of iron deficiency and a very high serum ferritin is commonly used as a marker of iron overload.
- Trial name
- NCT03777904
- Testing
- Serum Ferritin level, Serum Ferritin iron content, Urine Ferritin level
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Utah
Iron Deficiency, Anemia
Using Stable Iron Isotopic Techniques and Serum Hepcidin Profiles to Optimize Iron Supplementation
Oral iron supplementation (OIS) is a widely-used strategy to treat iron deficiency anemia. However, absorption of OIS is often low and response is variable.
- Conditions
- Iron Deficiency, Anemia, Iron Deficiency Anemia
- Trial name
- NCT01785407
- Testing
- Iron Supplement (Ferrous Sulfate Dried)
- Where
- Switzerland
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Anemia of Chronic Disease
Pharmacokinetics/Pharmacodynamics of NOX-H94 in the Human Endotoxemia Model
The purpose of this study is to assess the effect of the anti-hepcidin Spiegelmer NOX-H94 on iron homeostasis during systemic inflammation induced by endotoxin.
- Trial name
- NCT01522794
- Testing
- NOX-H94
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- TME Pharma AG
Hyperphosphatemia, Chronic Kidney Disease, Receiving Dialysis
A Study of a Novel Iron-based Phosphate Binder AP301 in Patients With Hyperphosphatemia in the U.S. and China
The goal of this clinical trial is to learn if AP301 could work in the patients receiving maintenance dialysis with elevated blood phosphate.
- Conditions
- Hyperphosphatemia, Chronic Kidney Disease, Receiving Dialysis, ESRD (End-Stage Renal Disease), Dialysis
- Trial name
- RESPOND-2 (NCT06933472)
- Testing
- AP301, AP301 Low Dose
- Where
- 42 sites in United States, China
- Volunteers
- 264 people
- Sponsor
- Alebund Pharmaceuticals
Serum Ferritin
Effects of Lactoferrin-enriched Whey on Iron Status in Females
The goal of this work is to study the effects of twice daily ingestion of a whey protein, rice protein, or maltodextrin drink enriched with lactoferrin- (200 mg), iron (6 mg) and vitamin B12 (5.2 µg) for 16-weeks on iron…
- Trial name
- NCT06232642
- Testing
- Lactoferrin, iron and B12 in Whey Protein, Lactoferrin, Iron and B12 in Rice Protein, Lactoferrin, Iron and B12 in Maltrodextrin
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Utah State University
Iron Deficiency (Without Anemia)
Hepcidin After Intravenous Iron Treatment
The aim of this study is to investigate the hepcidin hormone response after intravenous iron administration.
- Trial name
- NCT06264687
- Volunteers
- 10 people
- Sponsor
- Pierre-Alexandre Krayenbühl
Iron Deficiency Anemia of Pregnancy
Defining a Dosing Regimen With Maximal Absorption for Oral Iron Supplementation During Pregnancy
Iron deficiency anemia (IDA) is common during pregnancy and has adverse effects on the mother, fetus and newborn. Oral iron supplements are usually recommended to prevent ID/IDA during pregnancy.
- Trial name
- NCT04074707
- Testing
- Labeled iron solution (60mg and 120mg Ferrous Fumarate)
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Swiss Federal Institute of Technology
Chronic Kidney Diseases
Serum Ferritin In CKD Patients Serum Ferritin
Variability of serum ferritin in CKD patients and how these variables may affect the treatment decisions with iron supplements
- Trial name
- Ferritin (NCT05947552)
- Testing
- Serum ferritin
- Where
- Egypt
- Volunteers
- 55 people
- Sponsor
- Assiut University
Hereditary Haemochromatosis
Mi-iron - Moderately Increased Iron - is Reducing Iron Overload Necessary?
Haemochromatosis is a preventable genetic iron overload disorder. Untreated, it can shorten life due mainly to liver cirrhosis and cancer. It can be prevented by blood donation to maintain normal iron levels.
- Trial name
- Mi-iron (NCT01631708)
- Testing
- Erythrocytapheresis, Plasmapheresis
- Where
- 3 sites in Australia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Murdoch Childrens Research Institute
Iron Deficiency Without Anemia
Assessing the Immediate Increase in Serum Ferritin After Oral Iron Doses: an Experimental Study in Iron-deficient Women
Serum ferritin is a key indicator of body iron stores and is widely used in monitoring iron status. However, oral iron doses can acutely elevate SF levels, potentially biasing assessments of iron stores during supplementation.
- Trial name
- INFER 2 (NCT06851130)
- Testing
- ferrous sulfate 80 mg, ferrous sulfate 160 mg
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Swiss Federal Institute of Technology
Hypovitaminosis, Vitamin A Deficiency
Impact of Maternal Supplementation With Dual Megadose of Vitamin A
The purpose of this study is to evaluate the effect of maternal supplementation with 400,000 IU of oral retinol palmitate in the post-partum, the nutritional situation of the binomial mother-child, on growth and morbidity of…
- Trial name
- NCT00742937
- Testing
- vitamin A
- Where
- Brazil
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
CKD Stage 4
Serum Hepcidin, Haemoglobin Level and Iron Status in Chronic Kidney Disease Patients (CKD) With Anaemia
The current study is planned to assess possible relationships of serum hepcidin levels with haemoglobin levels, inflammation and iron statuses in stage 4 CKD patients.
- Trial name
- NCT04102319
- Testing
- serum hepcidin
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Assiut University
Transfusional Hemosiderosis
Palatability and Tolerability of Deferasirox Taken With Meals, With Different Liquids or Crushed and Added to Food
This single-arm, open-label, multi-center study enrolled 65 patients from approximately 20 centers. All patients who met the study criteria and were taking, beginning or resuming treatment with Deferasirox were allowed.
- Trial name
- NCT00845871
- Testing
- deferasirox:
- Where
- 23 sites in United States
- Volunteers
- 65 people
- Sponsor
- Novartis Pharmaceuticals
Beta-thalassemia Major, Sickle Cell Disease
Study Of Efficacy,Safety of Combined Deferasirox and Deferiprone Versus Combined Deferiprone and Desferal In Conditions of Iron Overload
Interventional Allocation: Randomized Endpoint Classification: Safety/Efficacy Study of combined chelation therapy Masking: Open Label Primary Purpose: Treatment of transfusional iron overload Primary Outcome Measures: The…
- Conditions
- Beta-thalassemia Major, Sickle Cell Disease, Iron Hemosiderosis
- Trial name
- NCT01511848
- Testing
- DFP (ferriprox) and deferasirox (ICL 670), DFP, DFO
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Healthy Volunteer, Mothers
Serum Ferritin Concentration in Kenyan Women and Their Preschool Children at Which the Body Begins to Upregulate Iron Absorption From the Diet
Using standardized methods, the investigators will perform stable iron isotope absorption studies in young Kenyan women and their preschool children (2-5y of age) with varying iron status to measure iron absorption from maize…
- Conditions
- Healthy Volunteer, Mothers, Preschool Children
- Trial name
- NCT06655909
- Testing
- consumption of maize porridge containing stable iron isotope
- Where
- Kenya
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Isabelle Herter-Aeberli
Anemia, Iron Deficiency
Ferritin as a Predictor for Anemia in Pregnancy
Anemia is a common problem with pregnant women around the world. There are high rates even within industrialized nations. The main cause of anemia in pregnancy is a lack of iron.
- Trial name
- NCT03565198
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- CAMC Health System
Anemia, Skin Condition
The Efficacy of Minayo Iron-rich Nutritional Gummies on Female Anemia, Skin Condition and Qi-blood Deficiency Syndrome
The goal of this randomized, double-blind, placebo controlled study is to learn about the efficacy of Minayo Iron-rich Nutritional Gummies on females who are aged 18-45 and suffer nutritional Anemia, skin condition and Qi-blood…
- Conditions
- Anemia, Skin Condition, Qi-blood Deficiency Syndrome
- Trial name
- NCT06869824
- Testing
- Minayo Iron-rich Nutritional Gummies, Common Gummies
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Hangzhou Agile Groups Network Technology Co., Ltd.
Iron Bioavailability
Regular Consumption of High Phytate Reduces Inhibitory Effect of Phytate on Iron Absorption
The purpose of this study is to investigate whether regular consumption of phytate dampens its negative effect on nonheme iron absorption.
- Trial name
- NCT02370940
- Testing
- High phytate intake, Low phytate intake
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Iowa State University
Renal Failure Chronic Requiring Hemodialysis
Serum NGAL Levels in Hemodialysis (HD) Patients; Relation to Iron Status, HD and Intravenous (IV) Iron Administration
The purpose of this study is to assess changes in serum levels of the siderophore binding protein NGAL by hemodialysis without and with intravenous iron administration
- Trial name
- NCT00560976
- Testing
- Iron Saccharate (Venofer)
- Where
- 3 sites in Israel
- Volunteers
- 100 people
- Sponsor
- Soroka University Medical Center
Sport Medicine, Sport
Ischemic Preconditioning - Perspectives of Use Vivio/in Vitro Studies
Both in sports and medicine, methods that can significantly contribute to improving the ability of tissues to perform their functions are constantly being searched.
- Conditions
- Sport Medicine, Sport, Physiological Adaptations, Sport Performance
- Trial name
- NCT07117643
- Testing
- Ischemic Preconditioning
- Where
- 2 sites in Poland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport