Clinical trials: Sex Differences
Allergic Asthma, Asthma
Gender Differences and SNPs in Asthmatic Patients
The GINA 2020 guidelines suggest that asthma affects approximately 300 million persons worldwide. Even if there is a specific drug treatment for each stage of disease (From mild to severe) in some patients it is not efficacy and…
- Trial name
- NCT04567212
- Testing
- genetic evaluation, MicroRNA evaluation
- Where
- 2 sites in Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Catanzaro
Vasodilation, Hypoxia
Sex-related Differences in Sympathetic Vascular Transduction in the Setting of Hypoxemia
The purpose of this project is to identify sex-related differences in the effect of hypoxia on sympathetic vascular transduction.
- Trial name
- NCT05256069
- Testing
- Propranolol Pill
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Turner Syndrome
Sex Differences in Early Brain Development; Brain Development in Turner Syndrome
Relative risk for many psychiatric disorders differs dramatically in males and females. Early-onset disorders, such as autism, occur more often in males; other conditions, such as schizophrenia, occur at similar rates in males…
- Trial name
- NCT00877942
- Where
- United States
- Volunteers
- 295 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Healthy Volunteers Are Studied
Pain Sensitivity in Acute Inflammatory Pain
Pain is a complex experience influenced by gender and genetics, and, by psychosocial and sensory experiences. Pain sensitivity is thus highly variable between individuals.
- Trial name
- PASORI (NCT01345877)
- Testing
- first degree cutaneous burn injury
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Aging
Sex Differences in Vascular Responses to Exercise
A key early event in cardiovascular disease development is endothelial dysfunction, characterized by impaired flow-mediated dilation.
- Trial name
- NCT04128215
- Testing
- Control Period, Exercise Period
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Florida
Healthy Population
Exploration of Gender Differences in Liver Aging
The liver is an important metabolic organ in the body. It participates in central metabolic activities to maintain systemic homeostasis. It is also one of the most vulnerable organs in the process of individual aging.
- Trial name
- NCT06591897
- Where
- China
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Functional Gastrointestinal Disorders, Overlap Syndromes
Overlap FGIDs and Genetic Polymorphism
1. To analyze the prevalence of overlap syndromes among NERD or RH, FD, and IBS patients, and to identify and to compare the differences in their characteristics and symptoms, and to determine their risk factors. 2.
- Trial name
- NCT04712617
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
HIV, Acquired Immunodeficiency Syndrome
Differences in Response to the Flu Vaccine Among Adults With HIV and Without HIV in Uganda
To use a systems biological approach to study the molecular signatures of innate and adaptive responses to vaccination in a HIV infected versus uninfected adult population in Kampala, Uganda.
- Conditions
- HIV, Acquired Immunodeficiency Syndrome, Influenza
- Trial name
- NCT01916759
- Testing
- Seasonal trivalent inactivated influenza vaccine (Vaxigrip®)
- Where
- Uganda
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Emory University
Male, Female
Sex-difference in Response to Resistance Exercise and Training
Sex-Difference in Response to Resistance Exercise and Training Given the importance of muscular strength for athletic performance as well as for daily activities in the general population-including clinical populations-and the…
- Conditions
- Male, Female, Healthy Adult
- Trial name
- WOMENRESIST S1 (NCT07692815)
- Testing
- Resistance exercise on a leg extension machine, Resistance training on a leg extension machine, Blood samples
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Healthy
Biological Response to Meal Ingestion: Gender Differences
Aim: to determine the effect of gender on the sensory and metabolomic responses to a standard probe meal. Participants (12 men and 12 women) will be instructed to eat a standard dinner the day before, to consume a standard…
- Trial name
- NCT03758482
- Testing
- Probe meal
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Sex Difference, Virtual Care
VR Learning Program for Sexual-and-gender-diversity Care
The study is designed to create a VR learning program for sexual-and-gender-diversity care and compare the short-term and long-term effects on caring behaviors in nursing students.
- Conditions
- Sex Difference, Virtual Care, Nursing Care
- Trial name
- NCT07535216
- Testing
- VR learning program for SGD care
- Where
- Taiwan
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University Hospital
Marijuana Dependence
Sex Differences in Attentional Bias in Marijuana-dependent Individuals
The purpose of this study is to explore sex differences in cognitive functioning and responses to marijuana-related items, and to determine whether stress impacts these measures.
- Trial name
- NCT01179425
- Testing
- Cognitive stressor
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Healthy, Alcohol Drinking
Binge Drinking of Alcohol Mixed With Energy Drinks
The purpose of the study is to assess the relevance of gender in the acute effects (subjective, physiological and driving-related skills) observed after controlled administration of alcohol in a binge-drinking pattern mixed with…
- Trial name
- ENERGYBINGE (NCT04616859)
- Testing
- Alcohol and Energy Drink (AmED)
- Where
- Spain
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Fundació Institut Germans Trias i Pujol
Overweight, Obesity
Can We Achieve 'high-quality' Weight Loss Through Supplementation and Exercise? the TRIM MUSCLE Study
The purpose of this study is to determine whether the combination of two dietary supplements: MUSCLE 5, which contains protein, creatine and vitamin D and TRIM 7, which contains beet extract, caffeine, coenzyme Q10, alpha lipoic…
- Trial name
- NCT05384431
- Testing
- Muscle5 and TRIM7, Mixed exercise
- Where
- Canada
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Exerkine Corporation
Nicotine Dependence, E-cigarette Use
Sex Differences in E-Cigarette Perception
This study examines differences between males and females in the appeal and addiction potential of menthol flavored e-cigarettes with and without nicotine.
- Trial name
- NCT07398976
- Testing
- Nicotine Level 1 (0mg/ml), Nicotine Level 2 (36mg/ml), Nicotine Level 3 (59mg/ml)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yale University
ADHD, Attention Deficit Hyperactivity Disorder
Adolescent Changes in Brain and Behavior in Boys and Girls With ADHD
The purpose of the study is to examine the developmental trajectory of response control in boys and girls with ADHD entering adolescence.
- Trial name
- NCT05927506
- Testing
- Other
- Where
- United States
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
CBD, Neural Responses
Sex Differences in Neural Response to Cannabidiol
This is a randomized, double-blind, within-subjects, cross-over design to assess neural changes following a single dose of cannabidiol (CBD) (600mg) versus placebo among healthy female volunteers.
- Trial name
- NCT04777643
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Yale University
Range of Motion, Articular, Muscle Stretching Exercises
Gender Differences in the Tolerance to Stretch
The effect of stretching on range of motion is believed to rely upon an increased tolerance to stretch. This suggests, that pain modulation has significance in regards to the effect of stretching.
- Trial name
- NCT04146506
- Testing
- Muscle stretching exercises
- Where
- Denmark
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University College of Northern Denmark
Gender
[18F]MC225 PET to Evaluate Gender Differences in BBB P-gp Function
P-gp is one of the main efflux transporters at the blood-brain barrier and is responsible for the transport of a variety of neurotoxic substances, including pharmaceuticals.
- Trial name
- NCT05618119
- Testing
- [18F]MC225
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Oral Hypofunction
Program of Community Oral Function Enhancement
The purpose of this study examined the effects of oral exercise on oral function among older adults in Taiwan, focusing on gender-related outcome differences.
- Trial name
- NCT06794814
- Testing
- oral exercise
- Where
- Taiwan
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University