Clinical trials: Sexual Activity
Gender Dysphoria, Adult, Blood Coagulation
Comparing the Effects of Sublingual Estradiol Treatment Versus Oral Estradiol With Cyproterone Acetate (CPA) Treatment on The Coagulation System in Transgender Women: A Prospective, Controlled Cohort Study
The goal of this clinical trial is to learn about the effects of different routes of estradiol administration on blood clotting in transgender women starting gender-affirming hormone therapy.
- Conditions
- Gender Dysphoria, Adult, Blood Coagulation, Coagulation Factors, Transgender Persons, M01.777.500
- Trial name
- NCT07145281
- Testing
- Estradiol (E2), Cyproterone Acetate (Androcur, BAY94-8367)
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
HIV Infections
Sexual Health Advocacy for Guys - a Text Messaging-based HIV Prevention Program for Guys Who Are Into Guys
SHAG is a text messaging-based HIV prevention program designed for cisgender sexual minority boys and men 13-20 years of age across the United States.
- Trial name
- SHAG (NCT06230367)
- Testing
- Sexual health advocacy for guys, Healthy lifestyle control
- Where
- 2 sites in United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Center for Innovative Public Health Research
Dyspareunia, Vaginal Dryness
Effectiveness and Safety of a Water-based and a Silicone-based Personal Lubricants With Sensory Action
This clinical investigation will look at the effectiveness and safety of two personal lubricants for the relief of intimate discomfort associated with vaginal dryness.
- Trial name
- NCT05644444
- Testing
- Lubricant A (sensate water-based personal lubricant) and Comparator A (non-sensate water-based lubricant), Lubricant B (sensate silicone-based personal lubricant) and Comparator B (non-sensate silicone-based personal lubricant)
- Where
- Germany
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
Bisexually-active Men, at Risk for HIV
Evaluation of a New HIV Prevention Intervention for Black Bisexually-active Men
Black men who have sex with men (MSM) have the highest rates of HIV infection in the United States and represent a population in need of new HIV prevention interventions.
- Trial name
- RISE (NCT01347164)
- Testing
- RISE life coaching intervention, HIV Counseling
- Where
- United States
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Public Health Management Corporation
Erectile Dysfunction
A Randomized Double-Blind Clinical Study of Intracavernosal OnabotulinumtoxinA Injection in Patients With Erectile Dysfunction Refractory to Phosphodiesterase-5 Inhibitors
This study aims to evaluate the clinical efficacy of intracavernosal treatment with onabotulinumtoxinA (Botox) in 114 men aged 30 years or older with erectile dysfunction who have not responded to first-line oral pharmacological…
- Trial name
- BTXDE (NCT07834164)
- Testing
- OnabotulinumtoxinA (Botox ®) Injections, Saline (0.9% NaCl)
- Where
- Spain
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Child Sexual Abuse
Smart Parents--Safe and Healthy Kids
The purpose of the proposed study is to assess the effectiveness of the addition of a single-session child sexual abuse (CSA) prevention module (Smart Parents - Safe and Healthy Kids) on improving parents' knowledge, attitudes…
- Trial name
- SPSHK (NCT04366687)
- Testing
- Smart Parents - Safe and Healthy Kids, Parents as Teachers
- Where
- 6 sites in United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Penn State University
Pregnancy
The Effect of Sex Education on Sexuality of Pregnant Women
Aim: In this study, it is aimed to determine the effect of sexual education given to pregnant women on attitudes towards sexuality and sexual response during pregnancy. The study will be carried out in two different groups.
- Trial name
- NCT05790967
- Testing
- Sexual Education
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- NESLİHAN YILMAZ SEZER
Hiv
Evaluation of the Preventing AIDS Through Live Movement and Sound (PALMS) Intervention for Minority Adolescents
The purpose of this program evaluation is to determine whether the Preventing AIDS Through Live Movement and Sound (PALMS) group-level intervention is effective in reducing HIV sex risk behaviors and increasing HIV testing of…
- Trial name
- NCT00137644
- Testing
- Preventing AIDS Through Live Movement and Sound (PALMS)
- Where
- United States
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Transcranial Magnetic Stimulation
Repetitive Transcranial Magnetic Stimulation as a Potential Tool to Reduce Sexual Arousal
Hyper- and hyposexuality occur frequently in a variety of psychiatric disorders and are difficult to treat. While there is meta-analytic evidence for the significant effect of non-invasive brain stimulation on drug and food…
- Trial name
- NCT04209309
- Testing
- repetitive transcranial magnetic stimulation
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Regensburg
Premature Ejaculation
Evaluation of the Safety and Effectiveness of the vPatch Device
Multi-center, international, prospective, randomized, double-blind, two-arms, sham-controlled, first-in-human clinical investigation.
- Trial name
- NCT03942367
- Testing
- Active Device (vPatch)
- Where
- 3 sites in Israel, Italy
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Virility Medical Ltd.
HIV, Sexually Transmitted Infections
Connecting Resources for Urban Sexual Health
The overall goal of the CRUSH project is to enhance and extend a response to the local HIV/AIDS epidemic in Alameda County with a set of innovative, evidence-based interventions across the continuum of HIV prevention and care…
- Trial name
- CRUSH (NCT02183909)
- Testing
- Testing and linkage to care for Y/MSM, Engagement and retention for HIV-positive Y/MSM in care, Engagement and retention for HIV-negative Y/MSM in sexual health services
- Where
- United States
- Volunteers
- 378 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Sexual Behavior
Feasibility Study of the Online High School Media Aware Program
This is a pretest-posttest feasibility study of Media Aware Sexual Health - High School, an interactive web-based comprehensive sexual health media literacy education program for high school students.
- Trial name
- FS-OHSMAP (NCT03855033)
- Testing
- Media Aware Sexual Health - High School
- Where
- United States
- Volunteers
- 367 people, healthy volunteers welcome
- Sponsor
- Innovation Research & Training
HIV/AIDS, Gender
Transgender Youth and PrEP: PK, Safety, Uptake & Adherence - Intervention Development
To address the critical scientific gaps in PrEP safety for transgender youth and to plan for appropriate implementation of PrEP in transgender youth communities, the study will be conducted in 3 integrated phases.
- Conditions
- HIV/AIDS, Gender, Behavior and Behavior Mechanisms
- Trial name
- NCT04077138
- Where
- 3 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hektoen Institute for Medical Research
Vaginal Discharge, Postcoital Vaginal Changes
In-Clinic Assessment of Vaginal Mucosal Safety Following Repetitive Use of the Livi Device
The goal of this clinical trial is to learn if the Livi postcoital tampon device is safe for repetitive use in sexually active women aged 18 years and older.
- Trial name
- NCT07445958
- Testing
- Livi Postcoital Tampon Device
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Atlantic Health System
HIV Serosorting
Development of an HIV Self-testing Intervention
This randomized controlled trial (RCT) evaluates whether HIV self-testing (HIVST) facilitates sexual harm reduction and reduces HIV transmission among HIV-negative MSM in China.The intervention group will be offered HIVST kits…
- Trial name
- NCT02999243
- Testing
- HIV self-testing, Harm reduction education
- Where
- China
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Tobacco Use, Smoking
A Facebook Intervention for Young Sexual and Gender Minority Smokers
The 2-year research plan will test the Put It Out Project (POP) in a pilot randomized trial (N=120) compared to TSP and two historical control conditions.
- Conditions
- Tobacco Use, Smoking, Tobacco Dependence, Tobacco Use Disorder
- Trial name
- POP (NCT03259360)
- Testing
- POP:, TSP:
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Erectile Dysfunction
Diagnostic Performance of a Flexible Penile Monitoring System for ED
This study aims to evaluate the diagnostic performance of a novel intelligent flexible penile monitoring system for erectile dysfunction (ED).
- Trial name
- NCT07762469
- Testing
- Intelligent Flexible Penile Monitoring System, RigiScan Plus
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bin Xu
Sexual Health
Role of Ashwagandha Extract (Capsule KSM-66 300 mg) in Improving Sexual Health in Healthy Men
The clinical study aims to evaluate Efficacy and Safety of KSM66 Ashwagandha Standardized Root Extract for Improving Sexual Health in Healthy Men by measuring sex hormone levels in participant's blood, analyzing results of…
- Trial name
- NCT05840731
- Testing
- Ashwagandha
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- SF Research Institute, Inc.
Alcohol Drinking, Social Acceptance
PLANTS Pilot Trial
This pilot cluster-randomized controlled trial will evaluate the PLANTS (Providing LGBTQ+ Adolescents with Nurturance, Trustworthiness, and Safety) course among high school staff.
- Conditions
- Alcohol Drinking, Social Acceptance, Depressive Symptoms, Bullying
- Trial name
- PLANTS (NCT05897827)
- Testing
- PLANTS, EMAILS
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Adherence, Medication, Risk Behavior
DOT Diary Optimization Pilot: A Pilot Study to Optimize the DOT Diary App to Measure PrEP Adherence
The researchers are working with a technology company, AiCure, to develop a smartphone app, DOT Diary, which combines two drug adherence strategies.
- Conditions
- Adherence, Medication, Risk Behavior, Pre-Exposure Prophylaxis, HIV Prevention
- Trial name
- NCT03387462
- Testing
- Emtricitabine / Tenofovir Disoproxil Oral Tablet, DOT Diary mobile app
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Public Health Foundation Enterprises, Inc.
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