Clinical trials: Sexual Transmitted Disease
HIV/AIDS
Direct and Spillover Impacts of a Community-Level HIV/AIDS Program
The HIV/AIDS crisis in Sub-Saharan Africa has left millions of children orphaned. These children, who are potentially infected with HIV themselves, are highly vulnerable and face some serious risks to their health and overall…
- Trial name
- FCC (NCT03880175)
- Testing
- FCC (Força à Comunidade e Crianças) program- direct beneficiary, FCC (Força à Comunidade e Crianças) program- non-direct beneficiary, Anti Stigma Information
- Where
- Mozambique
- Volunteers
- 3,658 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Human Immunodeficiency Virus, Tuberculosis
Usability Study of IeHS in Indonesia
Technology that has a particular focus on patients' needs and ease-of-use and -access plays a significant role in the development of e-health and m-health.
- Conditions
- Human Immunodeficiency Virus, Tuberculosis, Interpersonal Relations, Mobile Phone Use
- Trial name
- NCT04179344
- Testing
- Integrated e-healthcare services (IeHS) web-based app
- Where
- 3 sites in Indonesia
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Bekasi City Public Hospital
HIV Infections, Hepatitis C
Efficacy and Safety to Extend Treatment 24 Weeks in co-Infected HIV-HCV Genotype 1 and/or 4
A study concerning viral kinetic with 10 co-infected HIV-HCV patients on treatment with peginterferon alfa-2a + ribavirin o IFN + ribavirin was reported in Conference on Retroviruses and Opportunistic Infections 2002 by Dr.
- Trial name
- NCT00612755
- Testing
- Peginterferon alfa-2a + ribavirin
- Where
- 19 sites in Spain
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Hospital Clinico Universitario San Cecilio
HPV Infections, Cervical Cancer Stage IIa
Immunogenicity and Safety of Quadrivalent HPV Vaccine in Healthy Chinese Female Subjects Aged 9 to 19 Years
This phase 3 study will evaluate the immunogenicity and safety of Quadrivalent HPV recombinant vaccine in Chinese females aged 9 to 26 years
- Conditions
- HPV Infections, Cervical Cancer Stage IIa, Vaginal Cancer, Genital Wart
- Trial name
- NCT05027776
- Testing
- 2-doses Group among 9-14 years, 3-doses Group among 9-19 years, 3-doses Group among 20-26 years
- Where
- China
- Volunteers
- 1,348 people, healthy volunteers welcome
- Sponsor
- Shanghai Bovax Biotechnology Co., Ltd.
Condylomata Acuminata
An Investigational Study of Gardasil™ (qHPV Vaccine) in Reducing the Incidence of Anogenital Warts in Young Men (V501-020)
This study was conducted to demonstrate that Gardasil™ (quadrivalent human papillomavirus [qHPV] vaccine) 1) is well tolerated in young men, 2) reduces incidence of external genital lesions in young men, 3) reduces the incidence…
- Trial name
- NCT00090285
- Testing
- (Gardasil™) human papillomavirus (types 6, 11, 16, 18) recombinant vaccine
- Volunteers
- 4,065 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
HIV/AIDS
Evaluating Demand Creation Strategies for Voluntary Medical Male Circumcision (VMMC) in Kenya
The purpose of this study is to evaluate the impact of two interventions - Inter-Personal Communication [IPC] and Dedicated Service Outlets [DSOs] - in recruiting men aged 25-39 years for Voluntary Medical Male Circumcision…
- Trial name
- TASCO (NCT02497989)
- Testing
- Inter-personal Communication (IPC), Dedicated Service Outlets (DSO)
- Where
- Kenya
- Volunteers
- 2,785 people, healthy volunteers welcome
- Sponsor
- Impact Research & Development Organization
Penile/Perineal /Perianal Intraepithelial Neoplasia, Anal Intraepithelial Neoplasia
A Phase III Trial to Evaluate the Efficacy, Immunogenicity and Safety of a Recombinant Human Papillomavirus 9-Valent (Types 6, 11, 16, 18, 31, 33, 45, 52, 58) Vaccine (E.Coli) in Chinese Males
This phase III clinical trial was designed to evaluate the efficacy, immunogenicity and safety of a Recombinant Human Papillomavirus 9-Valent (Types 6, 11, 16, 18, 31, 33, 45, 52, 58) Vaccine (E.Coli) manufactured by Xiamen…
- Conditions
- Penile/Perineal /Perianal Intraepithelial Neoplasia, Anal Intraepithelial Neoplasia, Penile/Perianal/Perineal Cancer, Anal Cancer
- Trial name
- NCT06866574
- Testing
- Recombinant Human Papillomavirus 9-Valent (Types 6, 11, 16, 18, 31, 33, 45, 52, 58) Vaccine (E.coli), Aluminum Adjuvant
- Where
- 4 sites in China
- Volunteers
- 9,300 people, healthy volunteers welcome
- Sponsor
- Xiamen University
Hiv
Multi-product PrEP Delivery to Young Women Seeking Reproductive Health Services and Coverage of HIV Prevention
Following on the heels of large implementation science projects that participated in the launch of widespread daily oral PrEP availability, investigators will launch and study the integration of novel PrEP products - beginning…
- Trial name
- PrEMIA (NCT07076043)
- Testing
- Multiple Product PrEP Program, Routine Oral PrEP
- Where
- Kenya
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
HIV Infections
TMC278-TiDP15-C158 - A Study to Examine the Safety, Tolerability and Pharmacokinetics of a Single Dose or Three Successive Doses of Intramuscularly (IM) Injected Long Acting Formulation of TMC278
The purpose of this study is to examine the safety, local tolerability and pharmacokinetics (how drugs are absorbed in the body, how they are distributed within the body and how they are removed from the body over time) of a…
- Trial name
- NCT01031589
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Tibotec Pharmaceuticals, Ireland
HIV Infections
A Study to Investigate Safety, Tolerability, and Pharmacokinetics (PK) of VH4524184 and the Potential for Changes in Cytochrome P450 3A (CYP3A) Activity
This study is designed to investigate the safety, tolerability and PK of VH4524184 (GSK4524184) and the potential of VH4524184 to inhibit or induce CYP3A activity in healthy participants.
- Trial name
- NCT05631704
- Testing
- VH4524184, Midazolam
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- ViiV Healthcare
HIV/AIDS
Evaluation of Pre-Exposure Prophylaxis for High Risk Adolescent Girls and Young Women
To provide preliminary evidence about feasibility and acceptability of delivering PrEP to AGYW identified as potentially at high risk of HIV infection in Lilongwe city communities and two public facilities in Lilongwe, Malawi.
- Trial name
- NCT04044235
- Testing
- PrEP Cohort
- Where
- 2 sites in Malawi
- Volunteers
- 1,032 people, healthy volunteers welcome
- Sponsor
- Lighthouse Trust
HIV Prevention, Sexually Transmitted Diseases
HOME Study: a Combination Support Package to Increase Uptake of PrEP and HIV/STI Testing
Home HIV self-testing has been FDA approved and allows users to read their own HIV test results at home, while home sexually transmitted infection (STI) test self-collection allows men to use a swab at home and mail it in for…
- Conditions
- HIV Prevention, Sexually Transmitted Diseases, Pre-Exposure Prophylaxis
- Trial name
- NCT03138135
- Testing
- HOME Study intervention, Control
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Public Health Foundation Enterprises, Inc.
Human Immunodeficiency Virus (HIV)
SPL7013 Gel - Male Tolerance Study
The purpose of this study is to determine if SPL7013 Gel (VivaGel™) is safe when applied topically once a day for seven consecutive days to the shaft and glans of the penis in healthy male volunteers.
- Trial name
- NCT00370357
- Testing
- 3% w/w SPL7013 Gel (VivaGel™)
- Where
- Australia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Starpharma Pty Ltd
Substance Abuse, HIV Infections
Mirtazapine to Reduce Methamphetamine Use Among MSM With High-risk HIV Behaviors
Studies demonstrate that methamphetamine (meth) use is associated with high-risk sexual behavior among MSM, putting meth-using MSM at extraordinarily high risk for transmitting or acquiring HIV.
- Trial name
- NCT00497081
- Testing
- mirtazapine
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- San Francisco Department of Public Health
HIV Infections
Safety of and Immune Response to an Adenoviral HIV Vaccine (VRC-HIVADV014-00-VP) With or Without a Plasmid HIV Vaccine (VRC-HIVDNA016-00-VP) in HIV Uninfected Adults
The purpose of this study is to determine the safety of and immune response to an investigational HIV vaccine, VRC-HIVADV014-00-VP, with or without a second investigational HIV vaccine, VRC-HIVDNA016-00-VP, in HIV uninfected…
- Trial name
- NCT00124007
- Testing
- VRC-HIVADV014-00-VP, VRC-HIVDNA016-00-VP
- Where
- 3 sites in Kenya, Rwanda
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections
Male Partner Engagement in HIV Testing Using Partner-notification Slip Plus Oral HIV Self-testing Kit
HIV testing uptake among male partners of pregnant women remains low. But the optimal way to engage the male partners is unknown.
- Trial name
- NCT07488221
- Testing
- Partner Notification Slip plus HIV Self-test kit, Partner Notification Slip only
- Where
- Malawi
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Cervical Cancer, Human Papillomavirus Infection
Effect of Health Belief Model-Based Education on Cervical Cancer Knowledge and HPV Vaccine Attitudes in Women
This study evaluated the effect of a Health Belief Model-based educational intervention on women's knowledge of cervical cancer and their attitudes and beliefs toward HPV vaccination.
- Conditions
- Cervical Cancer, Human Papillomavirus Infection, Preventive Health Services
- Trial name
- HBM-HPV (NCT07521163)
- Testing
- Health Belief Model-Based Education
- Where
- Turkey (Türkiye)
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Muhammet Faruk Yigit
HIV/AIDS
Developing and Examining Evidenced-Based HIV Testing Messages
The goals of this study are to: 1. Develop a HIV test message tailored for African American women. A generic non-tailored message will be developed as well for comparison.
- Trial name
- NCT03433053
- Testing
- HIV Testing Message Intervention, Control
- Where
- United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
HIV/AIDS, Mobile Health
Evaluation of a Multi-Component Intervention to Support HIV Testing and Linkage to Services Among MSM in Peru
This study is testing a new program designed to improve access to HIV testing and help connect people with available treatment or prevention services, based on their test result.
- Conditions
- HIV/AIDS, Mobile Health, Feasibility Studies, Qualitative Research
- Trial name
- MERCURY (NCT07074899)
- Testing
- Multi-component HIV testing and linkage-to-services intervention
- Where
- 2 sites in Peru
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Cervical Cancer, Hpv
PopSci CHW4CervixHealth
Phase I: Validating self-collection kit by comparing their results with clinical Pap smear results in a cohort of 20 patients. Phase II: Evaluate the feasibility and acceptability of the CHW4CervicalHealth: Use of a…
- Conditions
- Cervical Cancer, Hpv, Human Papilloma Virus, HPV Infection
- Trial name
- NCT07336134
- Testing
- Evalyn® Brush, Copan Floqswab, CHW4CervicalHealth
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
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