Clinical trials: Sexual Wellness
HIV Infections, Sexually Transmitted Diseases, Viral
mLab App Plus: A Randomized Controlled Trial of a Mobile Health (mHealth) Intervention
Men who have sex with men (MSM), especially young men who have sex with men (YMSM), and transgender women (TGW) have some of the highest rates of HIV and syphilis diagnoses in the United States.
- Conditions
- HIV Infections, Sexually Transmitted Diseases, Viral, Syphilis
- Trial name
- NCT06059443
- Testing
- mLab App Plus
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Columbia University
Human Immunodeficiency Virus
Post-Exposure Prophylaxis in Health Care Workers
Objective: The objective of this study is to determine the safety and tolerability of Post-exposure Prophylaxis (PEP) with a regimen of Truvada + Kaletra among health care workers (HCWs) at Henry Ford Hospital.
- Trial name
- PEP (NCT01234116)
- Testing
- emtricitabine/tenofovir disoproxil fumarate
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Transgender Health, Gender Dysphoria
Evaluating Drug Interactions Between Doravirine With Estradiol and Spironolactone in Healthy Transgender Women
Transgender women living with Human Immunodeficiency Virus (HIV) may prioritize gender-affirming hormonal therapy over antiretroviral drug therapy.
- Conditions
- Transgender Health, Gender Dysphoria, Transgender Women, Human Immunodeficiency Virus
- Trial name
- IDENTIFY (NCT04283656)
- Testing
- Doravirine/Lamivudine/Tenofovir, Spironolactone 100mg, Estradiol 2mg
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Nicotine Dependence
Varenicline for Nicotine Dependence Among Those With HIV/AIDS
Among people diagnosed with HIV/AIDS, the widespread use of highly active antiretroviral therapy (HAART) has greatly improved survival rates and changed the leading causes of death, from AIDS-related diseases to cardiovascular…
- Trial name
- NCT01710137
- Testing
- Varenicline, Smoking Cessation Counseling
- Where
- United States
- Volunteers
- 179 people
- Sponsor
- University of Pennsylvania
Breast Cancer Female
Addressing Sexual Concerns in Breast Cancer: Patient Intervention Study
The goal of this study is to evaluate an educational video intervention (called Starting the Conversation) aimed to enhance breast cancer patients' beliefs about and communication with respect to sexual concerns.
- Trial name
- NCT03624972
- Testing
- Starting the Conversation Video, Sexual and Menopausal Health Resources
- Where
- United States
- Volunteers
- 153 people
- Sponsor
- Fox Chase Cancer Center
Transgender Persons, Sexual Health
The Experiences of Erotic and Sexual Risk of Transgender Men: Exploratory Research Design
Transgender male (TM) is the minority and difficult to reach-up group. Therefore, there is a lack of research on private issues involving TM, such as sex, eroticism, and sexual risk behavior.
- Trial name
- NCT05187442
- Testing
- questionnaire, interview
- Where
- Taiwan
- Volunteers
- 350 people
- Sponsor
- National Taiwan University
HIV Infections, Electronic Health Record
An Electronic Health Record-based Approach to Increase PrEP Knowledge and Uptake: the EMC2 PrEP Strategy
This study is being conducted to investigate a strategy that may improve knowledge and uptake of pre-exposure prophylaxis for HIV prevention (PrEP) among cisgender women in primary care.
- Conditions
- HIV Infections, Electronic Health Record, Primary Health Care
- Trial name
- NCT05709860
- Testing
- EMC2 PrEP Educational Tool, Discrete Scheduling of a Dedicated PrEP Visit
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Northwestern University
Reproductive Behavior, Sexual Behavior
We Are Here Now: a Multi-level, Multicomponent Sexual and Reproductive Health Intervention for American Indian Youth
N/E is a community-based participatory research (CBPR) multi-level, multi-component sexual and reproductive health (SRH) intervention, constructed on Ecological Systems Theory.
- Trial name
- NE (NCT03694418)
- Testing
- We are here now: a multi-level, multi-component sexual and reproductive health intervention for American Indian youth
- Where
- 2 sites in United States
- Volunteers
- 453 people
- Sponsor
- Montana State University
HIV
Home Self-Testing for HIV to Increase HIV Testing Frequency in Men Who Have Sex With Men (The iTest Study)
The purpose of this study is to determine whether the availability of home self-testing for HIV will increase HIV testing frequency among men who have sex with men without negatively impacting their risk for HIV acquisition.
- Trial name
- NCT01161446
- Testing
- Home HIV self-testing with OraQuick ADVANCE® Rapid HIV-1/2 Antibody Test
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of Washington
Alcohol Use, Tobacco Use
Journey of Transformation Curriculum for Native American Adolescents
The investigators will conduct a waitlist control trial to test the efficacy of the Journey of Transformation-Native Youth Health Leadership Program (JOT) in terms of delaying or reducing tobacco and other substance use and…
- Conditions
- Alcohol Use, Tobacco Use, Substance Use, Sexual Health
- Trial name
- JOT (NCT05274217)
- Testing
- Journey of Transformation-Native Youth Health Leadership Program curriculum
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Washington
Hiv, Minority Stress
Developing an Online Mindfulness-based Intervention to Reduce Minority Stress and HIV Risk Among Young Adult MSM - Aim 3
The overall aim of the research study is to develop and test a mindfulness-based program for young adult gay, bisexual, and queer men at risk for HIV (Brown University IRB approved protocol #2004002698).
- Conditions
- Hiv, Minority Stress, Mental Health Wellness 1
- Trial name
- MBQR (NCT05855655)
- Testing
- Mindfulness-Based Queer Resilience (MBQR)
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Brown University
Feasibility
The EMERGE Project: Feasibility of Assessing Economic and Sexual Risk Behaviors Using Text Messages in Young Adults
As part of the development of the Engaging Microenterprise for Resource Generation and Health Empowerment (EMERGE) Project, the study team will conduct a single-group study to examine the feasibility of assessing economic and…
- Trial name
- NCT03237871
- Testing
- Text-message survey and informational text messages
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Sexually Transmitted Infection
rPlan Multimedia Dual Protection Intervention to Reduce Health Disparities
The investigators will develop a digital application (app)-"rPlan dual protection" (rPlan)-to be used in the clinic waiting room prior to a gynecological and/or contraceptive visit.
- Trial name
- NCT02498067
- Testing
- rPlan dual protection waiting room app intervention
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Intravaginal Ring Use
Women's Input on Sexual Health
The purpose of this study is to answer the following question: How do user sensory perceptions and experiences (USPEs) for IVRS differ between initial and continued use and how can this knowledge help product developers better…
- Trial name
- WISH (NCT02057419)
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Teacher Training
Interventions to Improve Reproductive Health Among Adolescents
The proposed virtual training prototype will provide Making Proud Choices (MPC) facilitator trainees the opportunity to make decisions, build facilitator skills, practice core concepts and enhance self-efficacy with a virtual…
- Trial name
- NCT04227236
- Testing
- E-based virtual facilitator training for Making Proud Choices, In-person facilitator training for Making Proud Choices
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- RAND
HIV Infections
AmbassADDOrs for Health Study
The goal of the study is to evaluate Malkia Klabu ("Queen Club") in Tanzania, a loyalty program intervention that creates adolescent girls and young women (AGYW)-friendly drug shops where AGYW can access HIV prevention services…
- Trial name
- ADDO (NCT05357144)
- Testing
- Loyalty card program at drug shops & supply of HIVST and SRH products, Comparison drug shops
- Where
- 2 sites in Tanzania
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Mental Health Issue, Hiv
Healthy Mothers: an Intervention to Support Perinatal Women Living With HIV in Kenya
The investigators will recruit 40 pregnant women living with HIV divided into 2 groups (n=20 intervention group, n=20 control group).
- Conditions
- Mental Health Issue, Hiv, Breastfeeding, Exclusive
- Trial name
- NCT05219552
- Testing
- personalized lactation support
- Where
- 2 sites in Kenya
- Volunteers
- 40 people
- Sponsor
- University of California, San Francisco
LGBTQ, Sexual Behavior
A Trial of Online LGBTQ-affirmative Cognitive Behavioral Therapy to Reduce Depression and Associated Health Risks Among Young Adults
This study is to test the efficacy of an online CBT intervention (EQuIP) that addresses the pathways through which minority stress compromises LGBTQ young adults' co-occurring mental (e.g., depression) and behavioral (e.g.…
- Trial name
- NCT04408469
- Testing
- Online EQuIP, Self-monitoring control
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Yale University
HIV/AIDS
Brief Acceptance-Based Retention Intervention for Newly Diagnosed HIV Patients
The overall aim of this program of research is to test a newly developed intervention, Acceptance-Based Behavior Therapy (ABBT), to improve HIV patients' commitment to medical care.
- Trial name
- NCT04201288
- Testing
- Acceptance-Based Behavior Therapy (ABBT), Enhanced-Treatment-as-Usual (ETAU)
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Brown University
Rectal Cancer, Rectum
The Sexual Health of Rectal Cancer Patients
We know that treatment for rectal, colorectal or anal cancer can impact sexual function. This study aims to learn: How the treatment affects emotional and social well-being.
- Trial name
- NCT00712751
- Testing
- questionnaires, CSI-SH- Cancer Survivorship Intervention
- Where
- 2 sites in United States
- Volunteers
- 149 people
- Sponsor
- Memorial Sloan Kettering Cancer Center