Clinical trials: Sexual Wellness
HIV/AIDS, Substance Use Disorders
Feasibility and Acceptability of Digital Pills to Monitor PrEP Adherence in MSM With Substance Use
This study deploys a novel digital pill with Emtricitabine/Tenofovir (TDF/FTC) among MSM with substance use to monitor PrEP adherence.
- Conditions
- HIV/AIDS, Substance Use Disorders, Adherence, Medication
- Trial name
- DigiPrEP (NCT03842436)
- Testing
- Digital pill, Truvada
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Brigham and Women's Hospital
Unprotected Sex, Unsafe Sex
Health-E You: Reducing Unintended Pregnancies Among Hispanic Adolescents
Health -E-You is an interactive, individually tailored computer application (App) that was developed to educate adolescent girls about contraceptive methods and assist them in selecting a contraceptive method that meets their…
- Trial name
- NCT02847858
- Testing
- Health-E You: a computer-based intervention to improve the use of effective contraception among Hispanic adolescents
- Where
- 2 sites in United States
- Volunteers
- 1,360 people
- Sponsor
- University of California, San Francisco
Sexually Transmitted Diseases
Aspiring to Awesome- Patient Preference Privacy Selections in EMR
Health information technology, including health information exchange, offers the potential to improve care by providing an integrated view of relevant, integrated patient information from multiple health care providers practicing…
- Trial name
- NCT01862133
- Testing
- Patient preferences
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Indiana University
HIV Infections, Stigma, Social
HIV Prevention Peer Navigation for Justice Involved Women
Women involved in the criminal justice system have complex and highly stigmatized sexual and substance use risk profiles and are particularly vulnerable to, and experience, high rates of HIV.
- Trial name
- kINSHIP (NCT04680390)
- Testing
- Standard of care engagement practices, Peer Navigators Addressing INtersectional Stigma to Improve HIV Prevention Among Criminal-Justice Involved Women
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
HIV, Sexually Transmitted Diseases
Reducing Sexual Risk Behaviors and Improving Health for People at a Sexually Transmitted Infection Clinic
This study will determine whether showing an educational DVD to people at sexually transmitted infection clinics can reduce incidence of new infections and risky sexual behaviors and improve overall health.
- Conditions
- HIV, Sexually Transmitted Diseases, HIV Infections
- Trial name
- NCT00947271
- Testing
- DVD 1, DVD 2
- Where
- United States
- Volunteers
- 1,010 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Human Immunodeficiency Virus, Perinatal Depression
Adaptation of the Friendship Bench Intervention for HIV-infected Perinatal Women in Lilongwe
In many sub-Saharan African countries, the scale-up of lifelong antiretroviral treatment (ART) to all pregnant and breastfeeding women under Option B+ has the potential to radically improve maternal health and reduce…
- Trial name
- Periscope (NCT04143009)
- Testing
- Enhanced Friendship Bench, Enhanced Standard Care (Control), Adapted Friendship Bench
- Where
- 3 sites in Malawi
- Volunteers
- 92 people
- Sponsor
- University of North Carolina, Chapel Hill
Hiv, HIV/AIDS
AllyQuest Adherence App Intervention for HIV-positive Men Who Have Sex With Men and Transgender Women: Pilot Trial
AllyQuest (AQ) is a theory-informed smart phone application that supports HIV medication adherence for young men who have sex with men and young transgender women who have sex with men (YMSM/YTW) via behavior change, social…
- Conditions
- Hiv, HIV/AIDS, Medication Adherence, Sexual Behavior
- Trial name
- AQ2 (NCT03916484)
- Testing
- AllyQuest HIV Medication Adherence app-delivered intervention, AllyQuest HIV Medication Adherence app-delivered intervention + NSC
- Where
- 6 sites in United States
- Volunteers
- 71 people
- Sponsor
- University of North Carolina, Chapel Hill
Human Immunodeficiency Virus, Mental Health
Digital Star: HIV Prevention for Youth in Mental Health Treatment
Teenagers in mental health treatment are at greater risk for HIV and other sexually transmitted infections. This greater risk comes from many factors, some of which are related to poor emotion regulation and low self-confidence.
- Trial name
- DSTAR (NCT02921841)
- Testing
- D*STAR, D*HEALTH
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Rhode Island Hospital
Discrimination, Social, Health Care Utilization
Still Climbin': An Intervention to Improve Coping Among Black Sexual Minority Men
This study consists of a randomized controlled trial of a multi-session cognitive behavior therapy (CBT) group intervention that addresses coping with discrimination and medical mistrust among Black sexual minority men (SMM).
- Trial name
- NCT04587869
- Testing
- CBT Coping Intervention
- Where
- United States
- Volunteers
- 369 people, healthy volunteers welcome
- Sponsor
- RAND
HIV Infections
Telephone Support to Improve Adherence to Anti-HIV Medications
This study tested a system of nursing telephone support to determine if it improves adherence to antiretroviral therapy (ART) in at-risk, treatment-experienced people.
- Trial name
- NCT00988442
- Testing
- Enhanced nursing telephone support, Standard care
- Where
- 16 sites in United States
- Volunteers
- 59 people
- Sponsor
- Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
Pelvic Inflammatory Disease (PID)
Technology Enhanced Community Health Nursing (TECH-N) Study
The investigators are enrolling 350 young women 13-25 years old diagnosed with pelvic inflammatory disease (PID) in Baltimore and randomize them to receive community health nurse (CHN) clinical support using a single post-PID…
- Trial name
- TECH-N (NCT01640379)
- Testing
- Technology Enhanced Community Health Nursing
- Where
- United States
- Volunteers
- 286 people
- Sponsor
- Johns Hopkins University
Harassment, Non-Sexual, Harassment, Sexual
The Use of Mentoring to Promote Well-being for Female SMART Members
Women are highly underrepresented in the construction skilled trades. In addition to facing the industry's well-known physical risks, women are subjected to discrimination, harassment, and skills under-utilization.
- Conditions
- Harassment, Non-Sexual, Harassment, Sexual, Bullying, Workplace, Mental Stress
- Trial name
- NCT04247880
- Testing
- Mentoring program
- Where
- 19 sites in United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Washington
HIV Infections, Pregnancy Related
Happy Homes, Healthy Families: A Relationship Strengthening Intervention for Pregnant Couples Affected by HIV in Zambia
The objective of this study is to test the preliminary efficacy of a novel couples' counseling intervention to promote the health of pregnant women living with HIV in Lusaka, Zambia.
- Trial name
- NCT04729413
- Testing
- Couples Counseling, Enhanced Standard of Care
- Where
- Zambia
- Volunteers
- 478 people
- Sponsor
- University of Colorado, Denver
Opioid-use Disorder, Adherence, Medication
Social Networks and Methadone Maintenance Treatment Retention and Antiretroviral Therapy Retention in Tanzania
Investigators will adapt the Brief Social Behaviour and Network Therapy (B-SBNT) intervention developed to facilitate recovery among people receiving medication-assisted treatment for opioid use disorder in the United Kingdom.
- Conditions
- Opioid-use Disorder, Adherence, Medication, HIV Infections
- Trial name
- NCT04479475
- Testing
- Supportive care through community support persons
- Where
- Tanzania
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
HIV
Comprehensive HIV Prevention Package for MSM in Southern Africa: Pilot Study (Sibanye Health Project)
The purpose of this study is to evaluate the acceptability and uptake of a combination package of biomedical, behavioral and community-level HIV prevention interventions and services for men who have sex with men (MSM) in South…
- Trial name
- NCT02043015
- Testing
- Condom choices, Condom-compatible lubricant choices, Couples HIV counseling and testing (CVCT)
- Where
- 3 sites in United States, South Africa
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Emory University
Breast Cancer
Clinician Communication About Sexual Health
The objective of this study is to adapt a previously tested brief intervention aimed at enhancing clinicians communication about sexual health (iSHARE) to a mobile web-based platform showcasing a two-part podcast and to assess…
- Trial name
- NCT04262219
- Testing
- iShare
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Fox Chase Cancer Center
Cardiovascular Diseases
The LEARN Study for CVD Prevention
The investigator is testing a virtual environment (VE) to address prevention of HIV-related comorbidities.
- Trial name
- LEARN (NCT05242952)
- Testing
- Gaming in a virtual environment
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Yale University
HIV Infections, Stigmatization
Stigma, Risk Behaviors and Health Care Among HIV-infected Russian People Who Inject Drugs
This study is a randomized controlled trial (RCT) among 100 HIV-positive people with injection drug use, which aims to test the feasibility of the SCRIPT intervention and evaluate its effectiveness on the reduction of…
- Conditions
- HIV Infections, Stigmatization, Substance Use
- Trial name
- SCRIPT (NCT03695393)
- Testing
- ACT Therapy
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- Boston Medical Center
HIV Infections, Sexually Transmitted Diseases
Multi-component Intervention to Train Providers to Promote PrEP for Girls and Women in the Deep South
The goal of this study is to adapt evidence-based curriculum on HIV epidemiology and PrEP prescription to train family medicine physician trainees to take a thorough sexual history and discuss HIV/STI prevention and PrEP options…
- Trial name
- PrEP Pro (NCT06487390)
- Testing
- PrEP Pro training intervention
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Alabama at Birmingham
Contraception Behavior
A Trial of an Adolescent Male Sexual Health Intervention
Early unintended fatherhood and rates of sexually transmitted infections remain national concerns, disproportionately affecting minority, underserved adolescent males, many of whom frequently use emergency departments (EDs) for…
- Trial name
- DrEric (NCT04969289)
- Testing
- Dr. Eric Digital Health Intervention
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Columbia University