Clinical trials: Sexually Transmitted Diseases, Viral
HIV Infections
Immune System Function Following Vaccination in HIV Infected Children Taking Anti-HIV Drugs
The purpose of this study is to determine immune system function following vaccination in HIV-infected children currently taking anti-HIV drugs.
- Trial name
- NCT00257127
- Testing
- Pneumococcal 7-valent conjugate vaccine, Pneumococcal polysaccharide vaccine, Hepatitis B vaccine
- Where
- 26 sites in United States, Puerto Rico
- Volunteers
- 101 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Human Immunodeficiency Virus (HIV), Acquired Immune Deficiency Syndrome (AIDS)
Pediatric Enhanced Surveillance Study
The Pediatric Enhanced Surveillance Study is a three part study of HIV-infected infants and children in South Africa to examine, clinical, immunologic, virologic, metabolic, psychosocial and behavioral outcomes.
- Trial name
- PESS (NCT02043769)
- Where
- 5 sites in South Africa
- Volunteers
- 396 people
- Sponsor
- Columbia University
HIV Infections
Switching HIV-1 Infected Subjects From a Highly Active Anti-Retroviral Treatment (HAART) Regimen Dosed Twice Daily or More Frequently to a Once-Daily Regimen
The purpose of this study is to demonstrate that virologically controlled HIV-infected individuals can successfully switch from a standard-of-care regimen dosed twice-daily or more frequently to a simpler once-daily (QD) regimen…
- Trial name
- NCT00135369
- Testing
- stavudine extended-release, lamivudine, efavirenz
- Where
- 47 sites in United States, Puerto Rico
- Volunteers
- 300 people
- Sponsor
- Bristol-Myers Squibb
Influenza, HIV Infections
Immunogenicity of Novel H1N1 Vaccination Among HIV-Infected Compared to HIV-Uninfected Persons
The purpose of this research is to determine the effectiveness of the novel H1Nl influenza (inactivated/killed formulation) vaccine among both HIV-infected and HIV-uninfected persons.
- Trial name
- NCT00996970
- Where
- 3 sites in United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
HIV Positive, HIV Negative
India HIV-CervCa Project
The investigators propose to prospectively study the difference in treatment (CTRT) completion and toxicities between HIV positive and HIV negative women in India with locally advanced cervical cancer receiving CTRT.
- Conditions
- HIV Positive, HIV Negative, Cervical Cancer
- Trial name
- NCT07167069
- Testing
- Radiation Therapy
- Where
- India
- Volunteers
- 180 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
HIV Infections
A Phase I Multicenter Study of the Safety and Immunogenicity of MN rgp120/HIV-1 Vaccine Given Either Alone or in Combination With IIIB rgp120/HIV-1 Vaccine in Healthy Adult Subjects (NOTE: Original Study Extended ONLY for Patients Previously Enrolled on VEU 009)
AMENDED 10/1/93: To evaluate the influence of prior immunization with an rgp120 vaccine on immune response to a subsequent immunization with a different strain of rgp120 (VEU 009X extension - in patients previously enrolled on…
- Trial name
- NCT00001021
- Testing
- rgp120/HIV-1IIIB, rgp120/HIV-1MN
- Where
- 3 sites in United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV/AIDS, Cervical Dysplasia
Factors Predicting Persistence of Oncogenic HPV and Cervical Dysplasia in HIV Infected Kenyan Women
This study will utilize a longitudinal study design to better understand the natural history of oncogenic Human Papillomavirus (HPV) infections in Human Immunodeficiency Virus (HIV)-infected and HIV-uninfected Kenyan women…
- Conditions
- HIV/AIDS, Cervical Dysplasia, HIV Infections
- Trial name
- NCT04045652
- Where
- 3 sites in United States, Kenya and 1 more
- Volunteers
- 223 people
- Sponsor
- Indiana University
HIV Infections
Antiviral Activity of and Resistance to Lamivudine in Combination With Zidovudine, Stavudine, or Didanosine
To evaluate the efficacy, safety, and pharmacokinetics of lamivudine (3TC) combined with zidovudine (AZT), stavudine (d4T), or didanosine (ddI) in comparison with d4T or ddI monotherapy in HIV-infected patients with no prior…
- Trial name
- NCT00000838
- Testing
- Lamivudine, Stavudine, Zidovudine
- Where
- 32 sites in United States, Puerto Rico
- Volunteers
- 256 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections
Helping HIV Infected Patients in South Africa Adhere to Drug Regimens
Three or more anti-HIV drugs are taken in combination as part of a treatment regimen. These drug regimens must be closely followed in order to be successful.
- Trial name
- NCT00076804
- Testing
- Directly Observed Therapy
- Where
- South Africa
- Volunteers
- 274 people
- Sponsor
- Johns Hopkins University
Covid-19
Assess the Seroconversion Status of Health Care Workers Suspected or Confirmed Cases of COVID-19 Patients
A large number of Health Care Workers (HCWs) would be potentially getting exposed to COVID19. Some of them would be asymptomatic or may get subclinical symptoms.
- Trial name
- NCT04368884
- Where
- India
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Max Healthcare Insititute Limited
HIV Infections, Sexually Transmitted Diseases
Peer Intervention Latino Immigrant MSM
This study evaluates a peer intervention with HIV/STI self-testing kits to increase HIV/STI testing and PrEP uptake among Latino immigrant men who have sex with men.
- Trial name
- NCT03922126
- Testing
- Peer counseling, HIV/STI self-testing kits
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Washington
HIV-Infection
Immediate Versus Deferred Antiretroviral Therapy in HIV-infected Patients Presenting With Acute AIDS-defining Events
The purpose of this study is to compare the early versus deferred initiation of antiretroviral combination therapy consisting of tenofovir, emtricitabine and atazanavir/ritonavir in treatment naive patients who present with an…
- Trial name
- IDEAL (NCT01417949)
- Testing
- Time of starting antiretroviral therapy
- Where
- 17 sites in Germany
- Volunteers
- 61 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Hiv, Minority Stress
Developing an Online Mindfulness-based Intervention to Reduce Minority Stress and HIV Risk Among Young Adult MSM - Aim 3
The overall aim of the research study is to develop and test a mindfulness-based program for young adult gay, bisexual, and queer men at risk for HIV (Brown University IRB approved protocol #2004002698).
- Conditions
- Hiv, Minority Stress, Mental Health Wellness 1
- Trial name
- MBQR (NCT05855655)
- Testing
- Mindfulness-Based Queer Resilience (MBQR)
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Brown University
HIV Infections
Administration of Growth Hormone to Increase CD4+ Count in Patients Taking Anti-HIV Drugs
This study is designed to evaluate the ability of growth hormone (GH, also known as somatropin) to increase CD4+ cell counts in patients taking anti-HIV drugs.
- Trial name
- NCT00050921
- Testing
- somatropin, Hepatitis A virus, inactivated, Keyhole-Limpet Hemocyanin
- Where
- 13 sites in United States
- Volunteers
- 60 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Hepatitis C, HIV Infections
Coaching for HCV and HIV
The objective of this study is to determine the feasibility and acceptability of a peer recovery coach (PRC) intervention to improve linkage to hepatitis C (HCV) and/or human immunodeficiency virus (HIV) care, treatment…
- Conditions
- Hepatitis C, HIV Infections, Opioid-use Disorder
- Trial name
- NCT04314414
- Testing
- PRC brief motivational interview intervention, Phone contact
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Boston Medical Center
HIV Infection
Enhancement of Connect to Protect® (C2P)
The proposed study seeks to continue Connect to Protect® (C2P) community mobilization efforts that have developed coalitions that plan for and bring about structural changes for purposes of reducing HIV incidence and prevalence…
- Trial name
- NCT01492816
- Testing
- Community Mobilization
- Where
- 9 sites in United States
- Volunteers
- 927 people
- Sponsor
- University of North Carolina, Chapel Hill
HIV Infections, Sexually Transmitted Diseases
HORIZONS HIV Intervention
The Horizons Program will test the efficacy of a multi-session HIV prevention program for African American female teens attending reproductive health clinics in Atlanta, GA.
- Trial name
- HORIZONS (NCT00633906)
- Testing
- HORIZONS HIV Intervention, enhanced standard-of-care
- Where
- 3 sites in United States
- Volunteers
- 715 people, healthy volunteers welcome
- Sponsor
- Emory University
Infections, Papillomavirus
Human Papillomavirus Vaccine Safety & Immunogenicity Trial in Healthy Young Adult Women With HPV Vaccine (GSK1674330A)
Infection with human papillomavirus (HPV) has been clearly established as the central cause of cervical cancer. Indeed, certain oncogenic types of HPV can infect the cervix (part of the uterus or womb).
- Trial name
- NCT00478621
- Testing
- GSK Biologicals' HPV vaccine (GSK1674330A), Cervarix TM
- Where
- 3 sites in Belgium
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
HIV, AIDS
HIV/AIDS, Severe Mental Illness and Homelessness
This is a two-arm randomized controlled trial (RCT) for 308 seriously mentally ill adults (SMI) engaging in risky sexual and/or drug use behavior, comparing a brief HIV primary and secondary prevention intervention [Skills…
- Trial name
- NCT01172704
- Testing
- Skills Building - Motivational Interviewing
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
HIV Infection
HIV Maintenance Therapy With T-20 During HAART Interruption
This study will evaluate whether a drug called T-20 can slow or prevent a rapid return of HIV in the blood when HAART (highly active antiretroviral therapy) is stopped temporarily.
- Trial name
- NCT00013884
- Testing
- T-20
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
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