Clinical trials: Shock
Airway Disease
Characterisation of Large Airway Collapse During Exercise (LACE)
The large central airways (i.e. trachea and bronchi) act as a conduit to enable lower airway ventilation but also facilitate airway clearance during dynamic manoeuvres, such as coughing.
- Trial name
- LACE (NCT04264052)
- Testing
- CBE & MRI
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Cardiogenic Shock
CorVad Myocardial Infarction Complicated with Cardiogenic Shock Trial
Cardiogenic shock a serious complication of a heart attack (myocardial infarction). Despite evaluation of several new treatments during the last decade, the mortality in patients with cardiogenic shock still exceeds 50%.
- Trial name
- Corvad AMICS (NCT06886113)
- Testing
- Conventional circulatory support, CorVad
- Where
- China
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- Shenzhen Core Medical Technology CO.,LTD.
Patient Safety, Nurse Training
Evaluation of the Efficiency of a Training Program Developed For Newly Graduate Nurses
Brief Summary: This research is a randomized, pre-test post-test control group, parallel group experimental study to evaluate the effectiveness of the language training program developed for newly graduated nurses.
- Conditions
- Patient Safety, Nurse Training, Communication
- Trial name
- NCT06711484
- Testing
- Speak up traning program
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Gazi University
Nasal Obstruction
A New Treatment for Mechanical Nasal Obstruction
The research team has developed a prototype for an investigational mechanical nasal dilator and the investigators aim to evaluate its efficacy.
- Trial name
- NCT03456115
- Testing
- Mechanical nasal dilator
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Obesity
Effect of Shock Wave Therapy on Truncal Obesity and Lipid Profile in Obese Post Menopausal Women
This study aimed to evaluate the effect of six weeks extracorporeal shockwave therapy (SWT) on truncal obesity and serum lipids in obese postmenopausal women
- Trial name
- NCT05982002
- Testing
- shock wave, Moderate intensity aerobic exercise, Energy-restricted diet
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Aging
Chronic Passive Heating in Healthy Older Adults
Aging is associated with a decline in cardiovascular health, cognitive function and losses in muscle strength, with half or more of those over age 65 suffering from two or more comorbidities (e.g., heart disease, type 2…
- Trial name
- NCT05618197
- Testing
- Passive heating
- Where
- United Kingdom
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Portsmouth
Sepsis Syndrome
Use of a Live Attenuated Vaccine as an Immune-based Preventive Against COVID-19-associated Sepsis
The objective of this randomized clinical trial is to test whether administration of live attenuated MMR vaccine (measles mumps rubella; Merck) to eligible adults at highest risk for contracting COVID-19 (healthcare workers…
- Trial name
- NCT04475081
- Testing
- MMR vaccine
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Acute Respiratory Distress Syndrome, Corona Virus Infection
Knowledge, Attitude and Practice of Dental Students About COVID-19
Coronavirus disease 2019 (abbreviated "COVID- 19") is a pandemic respiratory disease that is caused by a novel coronavirus and was first detected in December 2019 in Wuhan, China.
- Conditions
- Acute Respiratory Distress Syndrome, Corona Virus Infection, Acute Lung Injury, Fever
- Trial name
- NCT04449081
- Testing
- Knowledge, Attitude, Practice, Awareness, Preference
- Where
- Malaysia
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- Melaka Manipal Medical College
Hemiplegic Shoulder Pain
Comparison of the Efficacy of Extracorporeal Shock Wave Therapy and Suprascapular Nerve Block in Hemiplegic Shoulder Pain
This study aimed to compare the effectiveness of extracorporeal shock wave therapy (ESWT) and suprascapular nerve block (SSNB) with conventional treatment for hemiplegic shoulder pain.
- Trial name
- ESWT-HSP (NCT07485192)
- Testing
- Conventional therapy group, suprascapular nerve block, Extracorporeal Shock Wave Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Kars State Hospital
Pancreatitis, Organ Failure, Multiple
PROOF: Pancreatitis-associated Risk Of Organ Failure
This is a prospective case control study that compares the initial immune response with severity and outcome in patients with acute pancreatitis.
- Trial name
- PROOF (NCT03075605)
- Volunteers
- 723 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Dysmenorrhea, Back Pain Lower Back
Effect of Shockwave Therapy on Low Back Pain in Primary Dysmenorrhea
Primary dysmenorrhea (PD), defined as menstrual pain without any structural lesions, usually begins shortly before or immediately after the onset of the menstrual cycle and commonly lasts for 48 to 72 hour
- Trial name
- NCT06762106
- Testing
- shockwave therapy, hot back
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Deraya University
Dengue Shock Syndrome, Dengue Hemorrhagic Fever
Safety of and Immune Response to DEN4 Vaccine Component Candidate for Dengue Virus
Infection with dengue viruses is one of the leading causes of hospitalization and death in children in several tropical Asian counties.
- Trial name
- NCT00919178
- Testing
- DEN4 Vaccine Candidate
- Where
- 2 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Septic Shock
Midodrine Use in Septic Shock
The investigators aim to perform a randomized, double-blind, placebo-controlled trial to investigate the efficacy of midodrine in decreasing time to IV vasopressor liberation in patients with septic shock.
- Trial name
- NCT03706053
- Testing
- Midodrine Hydrochloride
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Systemic Inflammatory Response Syndrome
Autonomic Nervous Activity During the Systemic Inflammatory Response in Trained and Untrained Healthy Volunteers
Critical illness, severe infection, extensive trauma or tissue damage cause an inflammatory (irritative) reaction in the body. This reaction affects the whole body and causes malaise, circulatory and cardiac changes, fever…
- Trial name
- NCT01592526
- Testing
- Endotoxin, Endotoxin + Nicotine
- Where
- Denmark
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Muscle Stiffness
Effect of Extracorporeal Shock Wave Therapy on Trapezius Muscle Stiffness
This study will examine whether extracorporeal shock wave therapy (ESWT) can reduce stiffness in the upper trapezius muscle. Muscle stiffness will be measured using a special ultrasound technique called shear-wave elastography…
- Trial name
- ESWT-Trapezius (NCT06934668)
- Testing
- Extracorporeal Shock Wave Therapy
- Where
- Slovenia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Primorska
Abdominal Obesity, Abdominal Obesity-Metabolic Syndrome
Metabolic Effectiveness of Extracorporeal Shockwave on Abdominal Adiposity
Egyptian Ministry of Health and Population's Preventive Sector, have named obesity as one of the top contributors to the national mortality and morbidity.
- Conditions
- Abdominal Obesity, Abdominal Obesity-Metabolic Syndrome, Abdominal Obesity in Young and Middle Aged Adults
- Trial name
- NCT07686601
- Testing
- conventional balanced, low-calorie diet 1500 k/cal for 12 weeks, aerobic training program, extracorporeal shockwave therapy
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
Fibromyalgia
Comparison of the Effects of Fibromyalgia Syndrome
Massage therapy, one of the complementary and alternative treatments, is commonly used for fibromyalgia syndrome (FMS). It may help improve pain, anxiety, depression, and sleep disorders through the complex interaction of…
- Trial name
- NCT07082166
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Immunity, Vaccine Reaction
Efficacy and Tolerability of ABBC1 in Volunteers Receiving the Influenza or Covid-19 Vaccine
The immune system response needs to be forceful but also balanced for a rapid recovery from infection which avoids harmful overreactions.
- Conditions
- Immunity, Vaccine Reaction, Influenza, Covid19
- Trial name
- NCT04798677
- Testing
- ABBC1 Immunoessential
- Where
- Spain
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- AB Biotek
Hemorrhage
Comparison of Compensatory Reserve Index to Intravascular Volume Change and Stroke Volume
This study is designed to validate implementation of the CRI algorithm in the CypherOx CRI system. Healthy human subjects will undergo progressive reduction in central blood volume to the point of hemodynamic instability (defined…
- Trial name
- NCT01935427
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Flashback Technologies
Type 2 Diabetes Mellitus, Aging
Heat Shock Response is Blunted in Elderly Diabetic People But Recovered by Strength Training
The aim of this study was to compare the heat shock response (HSR) between healthy middle-aged adults, healthy elderly adults and type 2 diabetic elderly people.
- Trial name
- NCT03489083
- Testing
- Strength training, No Training
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul