Clinical trials: Short-Term Memory Impairment
Traumatic Brain Injury, Cognitive Impairment
Rehabilitation of Working Memory and Brain Plasticity After Traumatic Brain Injury: Plastim-MDTC
The aim of this study is to assess the brain correlates, as assessed with multimodal MRI, of working memory training in patients with severe traumatic brain injury (TBI)
- Trial name
- Plastim-MDTC (NCT03513133)
- Testing
- working memory training
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Centre d'Investigation Clinique et Technologique 805
Postoperative Cognitive Dysfunction, Mild Cognitive Impairment
Cognitive Changes After Major Joint Replacement
Patients assume that cognitive performance rapidly returns to baseline after anesthesia and surgery. Several studies have shown that one week after major non-cardiac surgery about 27% of patients have postoperative cognitive…
- Conditions
- Postoperative Cognitive Dysfunction, Mild Cognitive Impairment, Delirium, Cognitive Deficit
- Trial name
- Cognigram (NCT02964221)
- Testing
- Cognitive Testing
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dr. Stephen Choi
Schizotypal Personality Disorder, SPD
A D1 Agonist For Working Memory
The purpose of the study is to examine the effects of the administration of a drug called DAR-0100A on attention and memory in persons with schizotypal personality disorder (SPD).
- Trial name
- NCT02507206
- Testing
- DAR 0-100A
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Antonia New
Healthy, Amusia, Congenital
Auditory Deficits in Congenital Amusia (AMUSIE CONGENITALE)
The project studies auditory deficits in congenital amusia at the behavioral and neurophysiological levels. The auditory processes investigated are pitch discrimination, short-term memory, sound-induced emotions.
- Trial name
- NCT03094624
- Testing
- Neuropsychological and neurophysiological tests, Experiment 1, Experiment 2
- Where
- France
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Dementia, Mild Cognitive Impairment
Dual-Task Training for People With Mild Cognitive Impairment and Mild Dementia
Evidence shows that people with dementia have a higher prevalence of sleep disturbance, cognitive decline, behavioral disturbance, and experience motor dysfunction. These symptoms are interrelated.
- Conditions
- Dementia, Mild Cognitive Impairment, Older Adult
- Trial name
- DTT (NCT06348810)
- Testing
- Dual-task training, Cognitive training, Motor training
- Where
- Indonesia
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Mild Cognitive Impairment, Memory Impairment
Enhancing Frontal Lobes Plasticity in Mild Cognitive Impairment
More than 5 million people live with Alzheimer's dementia (AD) in North America. No effective treatment exists yet probably because by the time AD has developed it is too late to intervene.
- Trial name
- PAS-MCI (NCT04583215)
- Testing
- Paired Associative Stimulation (PAS)
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Schizotypal Personality Disorder, SPD
CRT-Guanfacine for SPD
This is a study to assess the efficacy augmenting cognitive remediation therapy (CRT) with a pharmacological agent for individuals with schizotypal personality disorder (SPD).
- Trial name
- NCT02524899
- Testing
- Cognitive Remediation Therapy, Guanfacine
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Aphasia, Acquired, Short-Term Memory Impairment
Short-term Memory Assessment in Patients With Poststroke Aphasia
Background and aim There is a growing awareness that people with aphasia (language problems) after a stroke often have difficulties with their short-term memory (STM).
- Trial name
- NCT06068296
- Testing
- short term memory assessment, Oxford cognitive screen, Token Test
- Where
- 2 sites in Belgium
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Healthy
Evaluation of Consumption Safety and Effect of Mulberry Leaves and Vietnamese Coriander Based Instant Polyherbal Porridge on Working Memory and Bone Formation Markers
This study the investigators aimed to determine the effect of the herbal porridge containing the combined extract of mulberry and Vietnamese coriander (MP) on cognitive function and bone formation markers of menopausal women.
- Trial name
- NCT02562274
- Testing
- MP 50 mg/day, MP 1500 mg/day
- Where
- Thailand
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
Older Adults (60 - 85 Years Old), Mild Cognitive Impairment (MCI)
Non-invasive Stimulation of Deep Brain Structures to Modulate Working Memory
A study investigating the effects of non-invasive electrical stimulation of deep brain structures on working memory, attention, and executive functions involved in everyday activities.
- Trial name
- DEEPBRAIN (NCT07560904)
- Testing
- Non-invasive deep brain stimulation of striatum via transcranial temporal interference stimulation (20 Hz), Control striatal stimulation, Non-invasive deep brain stimulation of striatum via transcranial temporal interference stimulation (60 Hz)
- Where
- Czechia
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Masaryk University
Mild Cognitive Impairment
Working Memory and Physical Exercise Training in Patients With Mild Cognitive Impairment
The prevalence of dementia will double in the next three decades in the U.S.; effective treatment or prevention for dementia is urgently needed.
- Trial name
- NCT05948930
- Testing
- Progressive aerobic exercise, Adaptive cognitive training, Combined
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Memory Disturbances
Functional Magnetic Resonance Imaging Study of Jaw-tapping Movement on Memory Function
The purpose of this study is to examine the possibility of using jaw-tapping training as a self-exercise for developing memory and preventing dementia in elderly subjects with memory disturbances using functional magnetic…
- Trial name
- NCT01873664
- Testing
- Jaw-tapping
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kyunghee University Medical Center
Age-associated Memory Impairment
TMS for Investigating Memory Facilitation
The aim of this study is to investigate the effects of Transcranial Magnetic Stimulation (TMS) following a Paired Associative Stimulation (PAS) protocol on the memorization capacity of elderly individuals.
- Trial name
- NCT05462782
- Testing
- Transcranial Magnetic Stimulation (TMS) Cone Coil
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Cardiac Arrest, Cognitive Impairment
Modifying Working Memory With Brain Stimulation
The investigators want to investigate the effect of rTMS on working memory measured by the N-back task. This is a single case experimental design, ABAB.
- Trial name
- BROCA-NIBS (NCT06119620)
- Testing
- intermitted theta burst stimulation
- Where
- Netherlands
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Maastricht University
Healthy, Stress, Psychological
Effects of Microencapsulated Sublingual Glycine (Bidicin) on Cognitive Performance in Healthy Men After an Acute Stressor
The aim of this study is to assess whether intake of Glycine (MSG) leads to an increase of cognitive performance after an acute stressor compared to placebo.
- Conditions
- Healthy, Stress, Psychological, Cognitive Impairment
- Trial name
- NCT03353441
- Testing
- Microencapsulated Sublingual Glycine (MSG)
- Where
- Germany
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Daacro
Memory Impairment, Anxiety
The Effect of Acupuncture on Anxiety and Working Memory
This study endeavors to examine the relationship between acupuncture, anxiety, and performance on a test of working memory. In the study, all participants will complete the State-Trait Anxiety Inventory (STAI) survey to determine…
- Trial name
- NCT01492738
- Testing
- Acupuncture
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National University of Health Sciences
Mild Cognitive Impairment, Healthy Aging
Novel, Individualized Brain Stimulation, Network-based Approaches to Improve Cognition
Impaired working memory (WM) plays a crucial role in normal aging, in mild cognitive impairment (MCI) and cognitive decline associated with dementia, such as Alzheimer's disease (AD).
- Trial name
- NiBS-iCog (NCT04986787)
- Testing
- tACS, TMS, TIS
- Where
- Czechia
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Masaryk University
Healthy, Memory Impairment
The Effects AZD8529 on Ketamine-induced Impairment of Working Memory in Healthy Volunteers
The purpose of this study is to assess if ketamine will induce, in healthy volunteers, impairment of working memory and if the drug AZD8529 will block the effects of ketamine on working memory as assessed by functional magnetic…
- Trial name
- NCT00985933
- Testing
- AZD8529
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Working Memory, Inhibitory Control
BID WM Digital Intervention in Aging
The goal of this clinical trial is to learn if engaging with an digital intervention may improve cognitive function. The main questions it aims to answer are: 1.
- Conditions
- Working Memory, Inhibitory Control, Mild Cognitive Impairment (MCI), Aging
- Trial name
- NCT06918704
- Testing
- Coherence, Worder
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cognitive Impairment, Cognitive Decline
A Mechanistic Study to Investigate tDCS and Working Memory in MCI Patients
The current study is a mechanistic study to evaluate working memory gains from application of transcranial direct current stimulation (tDCS) in older adults with mild cognitive impairments (MCI) compared to cognitively healthy…
- Trial name
- AIM (NCT05998031)
- Testing
- Active tDCS
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Florida