Clinical trials: Shoulder Arthroplasty
Rotator Cuff Tear, Proximal Humerus Fractures
Clinical Outcome Comparison Between Medial and Lateral Offset Reverse Shoulder Arthroplasty
The purpose of this study is to prospectively evaluate two FDA approved implant designs for the Tornier Reverse Shoulder arthroplasty. The small difference in design is the amount of offset each implant has.
- Conditions
- Rotator Cuff Tear, Proximal Humerus Fractures, Malunions, Chronic Proximal Humerus Dislocations
- Trial name
- NCT01086202
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Pain, Postoperative
Liposomal Bupivacaine Versus Interscalene Nerve Block
The aim of this study is to compare two different pain management interventions in patients undergoing reverse total shoulder arthroplasty.
- Trial name
- NCT03929146
- Testing
- Exparel, Interscalene Nerve Block
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Rotator Cuff Injuries, Anesthesia; Functional
The Impact of a Preoperative Nerve Block on the Consumption of Sevoflurane in Total Shoulder Arthroplasty
Total arthroplasty surgery of the shoulder is performed under general anesthesia. Pain control for after the surgery can be achieved purely with intravenous and oral pain medication or in combination with freezing of the nerves.
- Trial name
- NCT04020601
- Testing
- Ropivacaine, Dextrose
- Where
- Canada
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Arthritis
Long Term Outcomes Follow-up of Glenoid Anchor Peg Component Fixation
The purpose of this study is to investigate if the use of autologous bone graft around the anchor-peg glenoid prosthesis correlates with (1.) bony apposition on computed tomography scans, (2.) decreased radiolucent lines, (3.) a…
- Trial name
- NCT02983357
- Testing
- CT, X-Ray, Physical assessment, Questionnaire
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Shoulder Arthroplasty
Interscalene Block With Liposomal Bupivacaine vs. Interscalene Block With Bupivacaine and Adjuvants
The purpose of this study is to determine whether the use of plain bupivacaine with common adjuvants for interscalene block (ISB) provides non-inferior analgesic results compared to the use of liposomal bupivacaine for ISB, in…
- Trial name
- NCT03845894
- Testing
- Liposomal bupivacaine, Bupivacaine with adjuvants
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Reverse Total Shoulder Arthroplasty
Reverse Total Shoulder Arthroplasty in Patients Who Exceeded Their Life-expectancy: a Retrospective Study
Reverse total shoulder arthroplasty (RTSA) has become an established treatment for cuff arthropathy, severe osteoarthritis and in certain fracture cases.
- Trial name
- NCT04807322
- Testing
- Reverse Total Shoulder Arthroplasty (RTSA)
- Where
- Switzerland
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Bürgerspital Solothurn
Arthritis
Followup of Glenoid Fix Utilizing Auto Bone Graft in Shoulder Replacement
This is a case study to evaluate the adequacy of fixation and functional outcome of the glenoid anchor peg following autologous bone grafting around the prosthesis at the time of implant.
- Trial name
- NCT00670852
- Testing
- X-rays and CT scan
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Total Shoulder Arthroplasty, Iodine
Iodine Drapes Used in TSA
This study will directly compare the positive culture rate in shoulder arthroplasty using iodine-impregnated versus non-iodine-impregnated drapes used during surgery
- Conditions
- Total Shoulder Arthroplasty, Iodine, Shoulder Surgery
- Trial name
- NCT07721415
- Testing
- Total shoulder arthroplasty, Iodine impregnated drapes, Tissue Culture Samples
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- tnicholson
Opioid Use
Opioid Consumption and Disposal After Shoulder Arthroplasty
Opioid medications are widely used after many orthopedic procedures and are routinely prescribed after shoulder replacement surgery.
- Trial name
- NCT05525975
- Testing
- Educational materials
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Brendan M. Patterson
Rate of Positive Culture Growth for C.Acnes From Specimens Obtained From the Shoulders of Patients Undergoing Primary Shoulder Arthroplasty
Irrisept C.Acnes Study
A Prospective, Randomized, Controlled Trial Comparing An Irrisept Antiseptic Irrigation With 0.05% Chlorhexidine Gluconate versus Standard of Care Prophylaxis Chlorohexidine Wipes
- Trial name
- NCT03938467
- Testing
- Antiseptic Cleanser
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Orthopaedic Associates of Michigan, PC
Arthropathy Shoulder
The Role of Subscapularis Repair in Reverse Shoulder Arthroplasty
The overall goal of the study is to determine if repairing the subscapularis tendon during primary reverse shoulder arthroplasty effects short-term patient outcomes.
- Trial name
- NCT03727490
- Testing
- Repair, Standard Treatment
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Osteo Arthritis Shoulders, Proximal Humeral Fracture
Reverse Total Shoulder Arthroplasty: A Data Analysis on Patients Undergoing Reverse Total Shoulder Arthroplasty
The purpose of this study is to evaluate reverse total shoulder arthroplasty patients preoperative objective measurements and operative objective measurements to determine if there is any effect to postoperative outcomes.
- Conditions
- Osteo Arthritis Shoulders, Proximal Humeral Fracture, Rotator Cuff Tear, Rotator Cuff Tear Arthropathy
- Trial name
- rTSA (NCT03617107)
- Testing
- reverse total shoulder arthroplasty
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The Orthopaedic Research & Innovation Foundation
Arthritis Shoulder Glenohumoral Joint, Rotator Cuff Tear Arthropathy
Telerehabilitation After Shoulder Arthroplasty
The use of reverse total shoulder arthroplasty (RSA) has increased dramatically in the United States in recent years. The importance of postoperative physical therapy in the setting of anatomic total shoulder is well understood…
- Conditions
- Arthritis Shoulder Glenohumoral Joint, Rotator Cuff Tear Arthropathy, Arthropathy Shoulder
- Trial name
- NCT05499728
- Testing
- Telerehabilitation; physical therapy via telecommunication device (i.e. online video conferencing)
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Shoulder Arthroplasty
Prospective Low Dose CT for Total Shoulder Arthroplasty/Reverse Shoulder Arthroplasty
This study is a prospective, departmental funded study examining the outcomes of simulated Low Dose CT scans compared to Conventional Dose CT scans in patients who present to Duke University for total shoulder arthroplasty or…
- Trial name
- NCT05350319
- Testing
- A low-dose CT scan of the shoulder
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Duke University
Osteo Arthritis Shoulders, Avascular Necrosis of the Head of Humerus
Easytech Reversed Shoulder System Clinical Study
The purpose of the study is to collect data to demonstrate the safety and effectiveness of the Easytech Reversed Shoulder System for the treatment of patients who require a reverse total shoulder arthroplasty.
- Conditions
- Osteo Arthritis Shoulders, Avascular Necrosis of the Head of Humerus, Rotator Cuff Tear
- Trial name
- NCT03806842
- Testing
- Easytech group
- Where
- 6 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- FX Shoulder Solutions
Total Shoulder Arthoplasty
TSA Versus RSA in Patients >75
Total shoulder arthroplasty (TSA) has proven to be a predictable and successful operation for the treatment of symptomatic glenohumeral osteoarthritis (GHOA) with an intact rotator cuff.
- Trial name
- NCT04827277
- Testing
- Reverse Total Shoulder Replacement, Anatomic Total Shoulder Replacement
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Analgesia
Liposomal Bupivacaine Versus Non-liposomal Bupivacaine for Total Shoulder Arthroplasty
The objective of this study is to validate the analgesic efficacy of admixed Liposomal bupivacaine (LB) + bupivacaine compared with plain bupivacaine when injected for interscalene nerve block (ISNB) for total shoulder…
- Trial name
- NCT04974385
- Testing
- Liposomal bupivacaine, Bupivacaine
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Blood Loss, Anatomic Total Shoulder Arthroplasty
Investigation of Intravenous Tranexamic Acid With Anatomic and Reverse Total Shoulder Arthroplasty
To compare intravenous Tranexamic Acid (TXA) versus normal saline placebo to determine whether or not TXA administration reduces blood loss, decrease in hemoglobin, and rate of transfusions following anatomic and reverse total…
- Conditions
- Blood Loss, Anatomic Total Shoulder Arthroplasty, Reverse Total Shoulder Arthroplasty, Transfusion
- Trial name
- NCT02569658
- Testing
- Tranexamic Acid
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Cutibacterium Acnes Contamination
Wound Irrigation Comparative Effectiveness Study
The primary objective of this study is to compare the presence of C acnes in bacteriologic cultures taken from participant samples of subcutaneous and deep tissue prior to deep surgical irrigation using either Normal Saline…
- Trial name
- NCT06379919
- Testing
- Irrisept Irrigation, Saline Irrigation Solution Delivery
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Orthopaedic Education and Research Institute (dba Hoag Orthopedics)
Pain
Liposomal Bupivacaine in Total Shoulder Arthroplasty
This is a randomized, single blinded, standard of care controlled clinical trial. All adult patients over eighteen desiring shoulder arthroplasty will be eligible.
- Trial name
- EXP-TSA (NCT02570022)
- Testing
- Liposomal bupivacaine, Inter-scalene nerve block, Ropivacaine
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System