Clinical trials: Sickness Behavior
Major Depression, Dementia
Neurocognitive Outcomes of Depression in the Elderly
Late-life depression (LLD) and cognitive impairment (CI) are significant public health problems among older adults, and their co-occurrence markedly increases disease burden and dementia risk.
- Trial name
- NCODE (NCT00570583)
- Where
- United States
- Volunteers
- 795 people, healthy volunteers welcome
- Sponsor
- Duke University
Resting Heart Rate, Blood Glucose Control
Assessing the Effects of Cool Roofs on Indoor Environments and Health in Tavua, Fiji
Ambient air temperatures in Fiji are increasing due to climate change. Solutions are needed to build heat resilience in communities and adapt.
- Conditions
- Resting Heart Rate, Blood Glucose Control, Depression, Heat-related Symptoms
- Trial name
- NCT07592117
- Testing
- Cool roof
- Where
- Fiji
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Environmental Exposure, Health Behavior
The Barts Charity Children's Environmental Health Clinic
The study will be based from a newly formed NHS service, the children's environmental health service. Participants will be children with a known chronic respiratory condition.
- Conditions
- Environmental Exposure, Health Behavior, Asthma in Children, Environmental Illness
- Trial name
- BCCEHC (NCT06447974)
- Testing
- Exposure mitigations
- Where
- 2 sites in United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Alcohol Consumption, Sick Leave
Workplace Interventions Preventing Risky Use of Alcohol and Sick Leave
The aim of this study is to investigate the effectiveness of two workplace interventions (the Riskbruk model and Balance) in reducing risky alcohol consumption, sickness absence and presenteeism.
- Conditions
- Alcohol Consumption, Sick Leave, Workplace Interventions, Presenteeism
- Trial name
- WIRUS (NCT03466541)
- Testing
- Riskbruk, Balance
- Where
- Norway
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Stavanger
Mental Illness, Stigma, Social
Survey Experiment to Estimate Level of Mental Illness Stigma Based on Condition and Gender
This study aims to measure levels of mental illness stigma based on condition and gender of the participants and individual portrayed with mental illness.
- Trial name
- NCT06279962
- Testing
- Survey questionnaire
- Where
- Uganda
- Volunteers
- 379 people, healthy volunteers welcome
- Sponsor
- Yale University
Physical Functioning, Musculoskeletal Pain
Personalized Exercise Counseling to Promote Workability
The study design is a 2-arm randomized controlled trial with 6-month intervention period and follow-up at 6, 12 and 24 months among blue-color workers of Nokia City with reduced work ability and high number of musculoskeletal…
- Conditions
- Physical Functioning, Musculoskeletal Pain, Quality of Life, Physical Activity
- Trial name
- PEC-Nokia (NCT03854201)
- Testing
- Personalized Exercise Counseling (PEC)
- Where
- Finland
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- UKK Institute
ADHD, Parents
Psychoeducation in Parents of Children With ADHD
The objective of this study was to determine the effect of psychoeducation on the stress levels of parents of children with Attention Deficit and Hyperactivity Disorder (ADHD).
- Trial name
- NCT04138108
- Testing
- Psychoeducation
- Where
- Turkey (Türkiye)
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Critical Illness, Family
Psychosocial Outcomes in Families of COVID-19 ICU Patients
During the first part of the SRAS-COV2 pandemic, families were not allowed to visit the patients in ICU. We know that families can develop "Family-PICS" after their relatives' ICU stay.
- Conditions
- Critical Illness, Family, Psychological Stress, Covid19
- Trial name
- NCT04498507
- Testing
- HADS questionnaire
- Where
- Belgium
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Liege
Endotoxemia, Inflammation
Short-Chain Fatty Acids in Lypopolysaccharide-Induced Inflammation and Executive Function
Short-chain fatty acids (SCFAs) are substances produced by gut bacteria when they ferment dietary fiber. They can act as signals between the gut and the brain and may help regulate the body's immune and stress responses.
- Conditions
- Endotoxemia, Inflammation, Executive Function (Cognition)
- Trial name
- NCT07713641
- Testing
- Short-Chain Fatty Acid Colon-Delivery Capsules, Lipopolysaccharide (LPS)
- Where
- Belgium
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Decompression Sickness, SCUBA Diving
High Intensity Cycling Before SCUBA Diving Reduces Post-decompression Microparticle Production and Neutrophil Activation
The purpose of this study is to determine the impact of high intensity,anaerobic exercise, in the form of cycling, on SCUBA diving.
- Trial name
- NCT02064361
- Testing
- High intensity exercise
- Where
- 2 sites in United States, Croatia
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Split
Schizophrenia, Schizoaffective Disorder
Get Moving and Get Well - Pilot Study
Individuals with serious mental illness have greater morbidity from physical illness and mortality than the general population, but tend not to initiate or sustain engagement in health promotion interventions.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Bipolar Disorder, Major Depression
- Trial name
- GMGWP (NCT01884025)
- Testing
- Get Moving and Get Well, Health and Humor Class
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Communication
Emotion Regulation and Burnout Impact on Communication Documentation
This is a single-institution cohort study with two tiers. All participants receive the interventions in Tier 1. Tier 1 is an education study where participants can complete electronic surveys on their pre and post intervention…
- Trial name
- NCT03901547
- Testing
- Communication Skills Training, Profile feedback, Maslach burnout inventory
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Depressive Disorder, Major
Transcranial Low Intensity Focused Ultrasound Neuromodulation as a Probe to Study Human Emotion and Cognitive Function
The purpose of this study is to assess the low-intensity focused ultrasound pulsation (LIFUP) neuromodulation on emotion processing in healthy individuals, and to assess the overall safety of the LIFUP to stimulate or inhibit…
- Trial name
- NCT05194332
- Testing
- LIFUP sonication to the amygdala
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Febrile Illness
Knowledge, Attitudes, Perceptions and Behaviors of Healthcare Professionals and the General Population Regarding Vaccination During Febrile Illness
Patients and healthcare professionals often lack adequate information regarding the possibility of vaccinating during febrile illnesses due to limited data.
- Trial name
- NCT06959420
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Emotional Stress, Work Related Illnesses
A Mindfulness Based Intervention as a Key Component of Successful Workplace Functioning and Personal Well-being
This study will evaluate the effectiveness of an 8-week program in Mindfulness-Based Stress Reduction (MBSR) in reducing work absences and improving the well-being of healthcare workers.
- Conditions
- Emotional Stress, Work Related Illnesses, Burnout, Professional, Burnout Syndrome
- Trial name
- NCT03969771
- Testing
- Mindfulness-Based Stress Reduction (MBSR)
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Mental Disorders, Affective Disorders
A Pilot Study of Boredom in a Community Sample of Adolescents and a Clinical Sample of Adolescents
The aim of the following pilot study is to examine boredom in a community sample of adolescents and a clinical sample of adolescents.
- Conditions
- Mental Disorders, Affective Disorders, Anxiety Disorders, Attention Deficit and Disruptive Behavior Disorders
- Trial name
- NCT00163865
- Where
- Australia
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Bayside Health
Occupational Stress, Occupational Neurosis
Managing Minds at Work: A Feasibility Pilot Trial
This feasibility pilot cluster RCT aims to pilot and feasibility test an online training toolkit (Managing Minds at Work) for line managers to develop their knowledge and confidence in preventing work-related stress and promoting…
- Conditions
- Occupational Stress, Occupational Neurosis, Mental Health Wellness 1, Absence
- Trial name
- NCT05154019
- Testing
- Managing Minds at Work Online Training
- Where
- United Kingdom
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Critical Illness
Effect of Early Physical Exercise on Pulmonary Ventilation and Recruitment
In the critically patient bed rest and immobilization are some of the responsable of the development of respiratory complications.
- Trial name
- EFRA (NCT02226406)
- Testing
- A: Chair - Leg Cycle ergometer, B: Chair - Arm Cycle ergometer, C: Walk in place
- Where
- Belgium
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
PTSD, Psychiatric Illness
Killing Pain - Use of Analgesic, Sedative and Anxiolytic Medication and the Development of Psychiatric Illness in Adolescents
Prescription of analgesic, sedative, and anxiolytic medication for children and adolescents is increasing in Western countries. In recent decades, rates have also increased in Norway, despite a relatively restrictive prescription…
- Conditions
- PTSD, Psychiatric Illness, Prescription Drug Dependence, Addiction
- Trial name
- NCT04336605
- Testing
- Age & Development, Socioeconomy, Traumatic Events
- Where
- Norway
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- Norwegian Center for Violence and Traumatic Stress Studies
Mental Illness, Behavior Disorders
Up To Me: Erasing the Stigma of Mental Illness on College Campuses
This is a three-lesson, disclosure-based stigma reduction program meant to reduce barriers to community living and participation for college students with psychiatric disabilities.
- Conditions
- Mental Illness, Behavior Disorders, Severe Mental Illness, Psychiatric Diagnosis
- Trial name
- NCT05784818
- Testing
- Up To Me Intervention + No Booster, Up To Me Intervention + Booster
- Where
- United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- University of South Florida