Clinical trials: Sickness Behavior
Schizophrenia, Schizoaffective
Exercise-based Program for Rehabilitation of Veterans With Severe Mental Illness
This is a hybrid1, effectiveness-implementation study of yoga-based exercises (YE) as an adjunctive tool for rehabilitation among persons with Severe Mental Illness (SMI).
- Conditions
- Schizophrenia, Schizoaffective, Bipolar Disorder 1
- Trial name
- ESHANTI (NCT05157620)
- Testing
- Yoga-based Exercise (YE), Wellness Lifestyle Program (WLP)
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- VA Office of Research and Development
Chronic Illness, Chronic Pain
Treating Comorbid Depression During Care Transitions Using Relational Agents
Depression is common among individuals with chronic illness such as chronic heart failure (CHF) or chronic obstructive pulmonary disease (COPD) and is a strong predictor of poor clinical outcomes and high rates of avoidable…
- Conditions
- Chronic Illness, Chronic Pain, Depression, Comorbid Depression
- Trial name
- RA-CBT (NCT02845102)
- Testing
- Pre-Post Feasibility
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Cancer
Effectiveness, Acceptability and Feasibility of a Communication and Care Coordinator (CCC) Model in Facilitating Serious Illness Communication (SIC) and Care in Patients With Cancer
The goal of this clinical trial is to evaluate the communication and care coordinator (CCC) model in a national cancer institute and assess the utility of the model in facilitating serious illness communication (SIC) and care for…
- Trial name
- CCC-Cancer (NCT07733973)
- Testing
- CCC Intervention
- Where
- Singapore
- Volunteers
- 560 people
- Sponsor
- National Cancer Centre, Singapore
Trauma, Nervous System
Northwest Therapies Trauma Psilocybin Study Compassionate Use Study
The on-boarding of unregulatable trauma in the United States has reached 20%, which is 1/5 of the population. A population of this magnitude, by definition has now reached an epidemic classification.
- Trial name
- NWTTPS (NCT05042466)
- Testing
- Trauma
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- NWTraumatherapies
Stress, Anxiety
The Wild Man Programme - a Nature-based Rehabilitation Enhancing Quality of Life for Men on Long-term Sick Leave
The aim of the present study is to examine whether the nature based 'Wild man Programme' can help to increase quality of life among men on sick leave compared to treatment as usual.
- Conditions
- Stress, Anxiety, Depression, Cardiac Disease
- Trial name
- NCT04073524
- Testing
- Nature-Body-Mind-Community, Treatment as usual
- Where
- Denmark
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Mental Disorder
VR Relaxation in Older Adults With Mental Illness
This clinical trial is exploring whether virtual reality (VR) can be a helpful and practical tool for reducing stress and anxiety in older adults receiving mental health care.
- Trial name
- NCT06973941
- Testing
- Virtual reality relaxation, Guided imagery relaxation
- Where
- Germany
- Volunteers
- 44 people
- Sponsor
- Charite University, Berlin, Germany
Opioid-use Disorder, Opioid-related Disorders
An Observational Study of Environmental and SocioEconomic Factors in Opioid Recovery
The RECOVER Study will examine clinical, environmental and socioeconomic factors in recovery from opioid use disorder (OUD) over a 24-month period following exit from a Phase III clinical program for a buprenorphine…
- Trial name
- RECOVER® (NCT03604861)
- Testing
- Not applicable - no defined intervention
- Where
- 35 sites in United States
- Volunteers
- 534 people
- Sponsor
- Indivior Inc.
Bipolar Disorder, Cardiovascular Disease
Self-Management Addressing Heart Disease Risk Trial
The purpose of this research study is to learn whether or not people with bipolar disorder can reduce their risk of heart disease and related conditions by having a Care Manager provide self management and care management.
- Trial name
- SMAHRT (NCT00499096)
- Testing
- Chronic care model for Bipolar Disorder
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- US Department of Veterans Affairs
Lyme Disease
A School-Based Intervention to Reduce Lyme Disease
Our overall purpose of this study is evaluate whether a short in-class Lyme Disease education program based on social learning theory and the Health Belief Model can impact a child's knowledge, attitude, and preventive behavior.
- Trial name
- NCT00594997
- Testing
- Education, Control (pre and post surveys)
- Volunteers
- 3,570 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Psychological Distress, Depression
Mobile Mindfulness to Improve Psychological Distress After Critical Illness
Many survivors of the intensive care unit (ICU) suffer from persistent symptoms of depression, anxiety, and post-traumatic stress disorder (PTSD).
- Conditions
- Psychological Distress, Depression, Anxiety, Post-traumatic Stress Disorder
- Trial name
- NCT02701361
- Testing
- mobile mindfulness, standard mindfulness, education
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- Duke University
Medication Adherence
Cell Phone Support to Promote Medication Adherence Among Adolescents and Young Adults With Chronic Illness
Background: Adolescents and young adults (AYAs) with chronic illnesses often struggle to develop illness self-management skills.
- Trial name
- NCT04241627
- Testing
- Cell Phone Support
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Children's Hospital Los Angeles
Mental Illness, Tobacco Smoking
Decision Support for Smoking Cessation in Young Adults With Severe Mental Illness
Up to 77% of young people with severe mental illnesses smoke, a rate that is up to five times higher than the rate of daily smoking in other young adults.
- Conditions
- Mental Illness, Tobacco Smoking, Psychotic Disorders
- Trial name
- NCT01779440
- Testing
- Electronic Decision Support System
- Where
- 3 sites in United States
- Volunteers
- 58 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Depression, Mental Illness
Group Interventions for Suicidal African Americans
The investigator is conducting a hybrid efficacy-effectiveness randomized controlled trial with low-income African American suicide attempters.
- Conditions
- Depression, Mental Illness, Suicide, Suicidal Ideation
- Trial name
- NCT02227160
- Testing
- 10 weekly group meetings, Outpatient counseling and support groups
- Where
- United States
- Sponsor
- Emory University
Serious Mental Illness
Home-based Exercise for SMI
Older Veterans with serious mental illness (schizophrenia, schizoaffective disorder, bipolar disorder) have reduced physical function (endurance, strength, mobility) that leads to lower quality of life.
- Trial name
- NCT06078293
- Testing
- Home-based Exercise Program
- Where
- United States
- Sponsor
- VA Office of Research and Development
Chronic Multisymptom Illness
Telehealth Pilot for Veterans with Chronic Multi-Symptom Illness.
The objective of this pilot study is to examine the feasibility, safety, and acceptability of a telehealth meditation and physical activity (MAP) intervention among Veterans with chronic multi-symptom illness.
- Trial name
- Telehealth (NCT04164667)
- Testing
- Mental and physical (MAP) training intervention
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- War Related Illness and Injury Study Center
Postintensive Care Syndrome, Anxiety Disorder
Is Invasive ICU-treatment Associated With Mental Illness?
Understanding long-term complications after intensive care is important to be able to offer prophylactic and therapeutic measures to post-intensive care unit (ICU) patients.
- Conditions
- Postintensive Care Syndrome, Anxiety Disorder, Depression, PTSD
- Trial name
- NCT05137977
- Testing
- Intensive Care
- Volunteers
- 1,048,576 people
- Sponsor
- Uppsala University
Sport Injury, Diabetes
A Complex Health Promotion Intervention in Parasport - The Safe & Healthy Parasport Project
The interest in Para sport is steadily increasing. A concern is, though, that elite Para athletes report a high incidence of injuries and illnesses.
- Conditions
- Sport Injury, Diabetes, Health Behavior, Illness Behavior
- Trial name
- NCT05317130
- Testing
- Athlete health monitoring
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Lund University
Stroke, Influenza Human
Vaccination Nudges From Pharmacists
The goal of this individual-level pragmatic randomized policy trial is to learn about the impact of behavioural nudges via mailed letters on increasing influenza and travel vaccination uptake in Alberta, Canada.
- Conditions
- Stroke, Influenza Human, Influenza Vaccines, Health Behavior Change
- Trial name
- NCT07161739
- Testing
- Behavioural Nudge (Influenza Risk Reduction), Behavioural Nudge (Travel Vaccination Benefit)
- Where
- Canada
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Major Depression, Cancer
Omega 3 FA Supplements as Augmentation in the Treatment of Depression
To assess the efficacy of Omega 3 Fatty acid (Omega 3 FA) augmentation of desvenlafaxine (DVS) compared to placebo augmentation of DVS when used to treat depression and anxiety symptoms in patients with select medical conditions…
- Conditions
- Major Depression, Cancer, Diabetes, Cardiovascular Diseases
- Trial name
- NCT01803711
- Testing
- Desvenlafaxine, Omega 3 Fatty acids
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- UConn Health
Depressive Disorder, Somatoform Disorder
Physical Activity in Insurance Medicine: Effects on Patients With Psychiatric Disorders
We will conduct a randomized control trial to investigate whether and to what extent regular and guided group physical activity over 12 weeks (2 sessions à 1 hour/week) improves physical fitness and (physio-)psychological…
- Conditions
- Depressive Disorder, Somatoform Disorder, Anxiety Disorder, Personality Disorder
- Trial name
- PhysActIV (NCT01928264)
- Testing
- Physical activity
- Where
- Switzerland
- Volunteers
- 13 people
- Sponsor
- University Hospital, Basel, Switzerland