Clinical trials: Single Dose
Vaccine Effectiveness, HPV Vaccination
A Trial to Establish Non-inferiority of Immunogenicity of a Single-dose of CERVAVAC® Quadrivalent HPV Vaccine Compared to the Gardasil® Quadrivalent Vaccine Among Girls and Boys Aged 9 to 14 Years and in Girls/Women Aged 15 to 20 Years in Zambia
The goal of this study is to compare the immune response of the single dose of the CERVAVAC vaccine with the single dose of Gardasil vaccine in girls/women aged 9 to 20 and boys aged 9 to 14 at 6 months, 12 months and 24 months…
- Conditions
- Vaccine Effectiveness, HPV Vaccination, Single Dose, Immunogenicity
- Trial name
- CervALONE (NCT07256912)
- Testing
- quadrivalent HPV vaccine
- Where
- Zambia
- Volunteers
- 1,266 people, healthy volunteers welcome
- Sponsor
- International Agency for Research on Cancer
Single Ascending Dose, Healthy Subjects
A Study to Evaluate the Safety of GR2301 Injection in Healthy Volunteers.
This is a randomized, double-blind, placebo-controlled Phase I clinical trial evaluating the safety, tolerability, pharmacokinetics, immunogenicity, and preliminary pharmacodynamic characteristics of GR2301 injection in healthy…
- Trial name
- NCT07190716
- Testing
- GR2301 injection
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Genrix (Shanghai) Biopharmaceutical Co., Ltd.
Safety of a Single Dose of COMVIGEN Vaccine, Reactogenicity of a Single Dose of COMVIGEN Vaccine
Immunogenicity and Safety of Comvigen (Bivalent) Vaccine
This study will assess the safety, reactogenicity and immunogenicity of a single dose of Comvigen (Bivalent, ChulaCov19 BNA159.2) vaccine or BIVALENT Pfizer/BNT vaccine as a booster among healthy males and non-pregnant females…
- Conditions
- Safety of a Single Dose of COMVIGEN Vaccine, Reactogenicity of a Single Dose of COMVIGEN Vaccine, Immunogenicity of a Single Dose of COMVIGEN Vaccine, Safety of a Single Dose of BIVALENT Pfizer/BNT Vaccine
- Trial name
- NCT05930730
- Testing
- Comvigen (Bivalent, ChulaCov19 BNA159.2), BIVALENT Pfizer/BNT vaccine
- Where
- 2 sites in Thailand
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Pharmacokinetics, Food Affect
Safety, Tolerability and Pharmacokinetic Characteristics Evaluation on GST-HG121 Tablets
This phase I clinical study is a phase I clinical study on the safety, tolerability, pharmacokinetic characteristics and food effects of single / continuous administration in Chinese adult healthy subjects
- Conditions
- Pharmacokinetics, Food Affect, Single Ascending Dose, Maximum Applicable Dose
- Trial name
- NCT05576584
- Testing
- GST-HG121 tablets
- Where
- China
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Fujian Akeylink Biotechnology Co., Ltd.
Ascending Single Dose Study
Safety, Tolerability and Pharmacokinetics of TAK-438 in Healthy Male Participants
The primary purpose of this study was to evaluate the single dose safety and pharmacokinetics of TAK-438 in healthy Japanese men.
- Trial name
- NCT02123927
- Testing
- TAK-438
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Takeda
Outcomes of Single Oral Dose
Pharmacokinetic Effects of Oral DMAA
1,3-dimethylamylamine (DMAA) has become increasingly popular as a component of dietary supplements. It is also used within "party pills," often in conjunction with alcohol and other drugs, and has been associated with untoward…
- Trial name
- NCT01765933
- Testing
- DMAA
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Memphis
Metformin XR BE Study in Healthy Volunteers With Single and Multiple Dose
Bioequivalence Study of Two Formulations of 500 mg Metformin Extended Release Tablet
This was a single centre, single-blind, randomized, balanced, combined single dose study under fasting condition and multiple doses study under fed condition with normal diabetic-meal, two-period, two-sequence cross-over study to…
- Trial name
- NCT01677260
- Testing
- 500 mg metformin hydrochloride extended release caplet (test drug), 500 mg metformin hydrochloride prolonged release tablet (reference drug)
- Where
- Indonesia
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Dexa Medica Group
Phase 1, Single Dose
A First In Human Study In Healthy People To Evaluate Safety, Toleration And Time Course Of Plasma Concentration Of Single Inhaled Doses Of PF-05212372.
The purpose of this study in healthy people is to evaluate safety, toleration and time course of plasma concentration of single inhaled doses of PF-05212372.
- Conditions
- Phase 1, Single Dose, Safety, Toleration
- Trial name
- NCT01415102
- Testing
- PF-05212372
- Where
- Belgium
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Pfizer
a Single-Dose of Etoricoxib, Post-Operative Morphine Consumption
Pre-Emptive Analgesia Efficacy of Etoricoxib for Postoperative Pain
Taken together, studies of the value of pre-emptive analgesia are inconclusive. This randomized, double-blind, dose-ranging, placebo-controlled study was therefore designed to test that a reduction in post-operative morphine…
- Conditions
- a Single-Dose of Etoricoxib, Post-Operative Morphine Consumption, Total Pain Relief Over 8 Hr(TOPAR8), Post Transabdominal Hysterectomy
- Trial name
- NCT00149253
- Testing
- a single-dose of Etoricoxib before induction of anesthesia
- Where
- Thailand
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University