Clinical trials: Skeletal Muscle
Whole-body Protein Balance, Muscle Protein Synthesis
Effects of Protein Quality on Post-exercise Skeletal Muscle and Whole-body Protein Kinetics During Energy Deficit
The optimal EAA-containing protein format necessary to maximally stimulate muscle protein synthesis and optimize whole-body net protein balance during caloric deprivation has not been determined.
- Trial name
- NCT04004715
- Testing
- Essential Amino Acid Enriched Whey Protein, Whey Protein, Military Ration Entree
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Healthy
Concentration of MitoQ in Human Skeletal Muscle
The purpose of this study is to determine mitoquinone mesylate concentration levels in skeletal muscle samples obtained after intake of an acute oral dose of MitoQ.
- Trial name
- MitoQ/muscle (NCT04098510)
- Testing
- MitoQ
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Insulin Resistance
Mitochondrial Dysfunction and Insulin Resistance in Skeletal Muscle
The purpose of the study is to evaluate the link between insulin resistance and alterations in skeletal muscle mitochondrial redox homeostasis
- Trial name
- NCT04558190
- Testing
- Intralipid, 20% Intravenous Emulsion, MitoQ, Salbutamol
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Claudication
The Effect of Exercise Training on Skeletal Muscle Metabolism in Peripheral Artery Disease (PAD)
Specific Aim 1: To test the hypothesis that subjects with PAD and intermittent claudication have altered expression of genes that regulate skeletal muscle metabolism.
- Trial name
- NCT01231360
- Testing
- Exercise Training, Normal routine
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Aging
Protein Quantity and Quality in Older Subjects
After the age of ~50, humans start to lose muscle mass at a rate of about 1-3% per year. However, the loss of muscle mass beyond a certain point can make it increasingly difficult to perform activities of daily living such as…
- Trial name
- NCT05301179
- Testing
- Protein quantity and quality
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- McMaster University
Cardiovascular Diseases, Cerebrovascular Disorders
Dietary Patterns and Health Outcomes (Cardiovascular, Metabolic, Endocrine, Neurological, Skeletal Muscular, Cancer)
To study, prospectively, the association between dietary patterns and risk of health outcomes (cardiovascular, metabolic, endocrine, neurological, skeletal muscular, cancer) in cohort study of 116,671 women age 24 to 44 years at…
- Conditions
- Cardiovascular Diseases, Cerebrovascular Disorders, Metabolic Disease, Neoplasms
- Trial name
- NCT03328546
- Testing
- Dietary intake
- Volunteers
- 116,671 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Muscle Wasting
The Effect of Repeated Whole-body NMES Sessions With or Without Protein Intake on Muscle Protein Synthesis During 3 Days of Bed Rest in Healthy Young Volunteers
The goal of this clinical trial is to examine the effect of whole-body electrostimulation with protein intake on muscle protein synthesis, muscle mass and function during bed rest in healthy young adults (18-35 years).
- Trial name
- SPRINT (NCT07062562)
- Testing
- NMES, Protein bolus (20g), Standard nutrition
- Where
- Netherlands
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Placebo, Tetraselmis Chuii
TetraSOD® Supplementation and Skeletal Muscle Redox Gene Expression
Tetraselmis chuii (TetraSOD) is a marine microalgae that has been reported to improve antioxidant responses in human skeletal muscle cells treated with TetraSOD and to improve recovery from muscle damaging exercise in humans…
- Trial name
- NCT06822556
- Testing
- Tetraselmis chuii
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Muscle Hypertrophy, Muscle Fibre Activation
Lower and Higher Load Resistance Exercise Protocols: Acute Muscle Activation and Skeletal Muscle Hypertrophy
How much weight an individual lifts per workout does not dictate the relative increase in muscle size the individual gains following weeks of training, which is contrary to current strength training dogma.
- Trial name
- NCT03991117
- Testing
- resistance exercise
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- McMaster University
Insulin Resistance, Obesity
Impact of Trans Fatty Acids From Natural and Industrial Origin in the Induction of Insulin Resistance Development
The investigators' project has as for principal objective to understand the impact of trans fatty acids from dairy products and industrial origin on the development of insulin resistance in obese woman.
- Trial name
- Trans-Insulin (NCT00617435)
- Testing
- vaccenic acid enriched diet, Elaidic acid enriched diet, control diet
- Where
- 2 sites in France
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Chronic Kidney Diseases
Skeletal and Respiratory Muscle Strength, Pulmonary Function, Exercise Capacity and Physical Activity in Pediatric Chronic Kidney Disease
Studies examining musculoskeletal strength, respiratory function and muscle strength, physical activity level and exercise capacity in children with CKD and evaluating the relationships between these parameters have not been…
- Trial name
- NCT05354726
- Testing
- Assessments parameters
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Hypertension
Insulin Action: Role of Skeletal Muscle and Insulin-Mediated Blood Flow
The overall objective of this proposal is to examine the contribution of changes in total body fat, enhancement in insulin-mediated vasodilatation and enhancement in endothelium-derived nitric oxide production to the improvements…
- Trial name
- NCT00018304
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Cystic Fibrosis
Relationship of Skeletal Muscle Thickness, Strength, and Diaphragm Function in Adults With CF
31 CF patients and 23 healthy sex and age-matched volunteers were enrolled. All subjects underwent pulmonary function tests, 6-minute walking tests.
- Trial name
- NCT04892485
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Marmara University
Muscle Damage
Influence of Non-steroidal Anti-inflammatory Drugs (NSAID) on Muscle Regeneration
The purpose of this study is to determine the influence of non-steroidal anti-inflammatory drugs (NSAIDs) on muscle regeneration. The investigators' hypothesis is that ingestion of NSAID will delay or impair muscle regeneration.
- Trial name
- NCT00832663
- Testing
- NSAID
- Where
- Denmark
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Cardiac Ageing, Physical Activity
The Cardio-Sarcopenia Study
The use of surrogate markers such as body mass index (BMI) as a target outcome of physical activity may not be appropriate in older adults who are at risk of muscle sarcopenia.
- Conditions
- Cardiac Ageing, Physical Activity, Older Adults, Sarcopenia
- Trial name
- NCT05203406
- Where
- Singapore
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Heart Centre Singapore
Insulin Resistance, Type 2 Diabetes
Microvascular Dysfunction and the Development of Whole-body Insulin Resistance
This study aims to elucidate the role of the microcirculation in the development of whole body insulin resistance. The investigators hypothesize that impaired insulin signaling in the vasculature is an early phenomenon in the…
- Conditions
- Insulin Resistance, Type 2 Diabetes, Obesity
- Trial name
- DESIRE (NCT02628301)
- Testing
- Hypercaloric diet, Normocaloric diet
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Healthy
Study of Muscle Repair Following Exercise in Young and Elderly People
The aim of this study is to understand how healthy muscle repairs in response to eccentric exercise by evaluating functional, metabolic and molecular measures.
- Trial name
- MDS (NCT02174692)
- Testing
- Exercise
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Skeletal Muscle Performance
Photobiomodulation Therapy Combined With Static Magnetic Field on the Subsequent Performance
There is evidence about the effects of photobiomodulation therapy (PBMT) alone and combined with static magnetic field (PBMT-sMF) on skeletal muscle fatigue, physical performance and post-exercise recovery in different types of…
- Trial name
- NCT04934709
- Testing
- Active PBMT-sMF
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Skeletal Muscle Physiology
Proteome Remodelling
The purpose of the project is to investigate the proteome signature dynamics and remodelling in human skeletal muscle induced by exercise training
- Trial name
- NCT04136457
- Testing
- Endurance training, Resistance training, Sprint training
- Where
- Denmark
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Morten Hostrup, PhD
Skeletal Muscle Damage, Muscle Damage
Whey and Soy Protein Supplementation in Football Players
In a constant effort to find ways to make a quicker recovery between demanding workouts and football matches, this study is the first to investigate the benefits of protein supplementation, and compares two types of proteins, an…
- Conditions
- Skeletal Muscle Damage, Muscle Damage, Athletic Performance
- Trial name
- NCT03753321
- Testing
- Whey protein, Soy protein
- Where
- Greece
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Thessaly