Clinical trials: Skeletal Muscle Recovery
Ketosis, Hypoxia
The Effect of Butanediol Ingestion on Skeletal Muscle Angiogenesis in Hypoxia
This study specifically aims to elucidate the effects of intermittent exogenous ketosis (IEK) as well as hypoxia on muscular pro-angiogenic factors- after a 60-min HIIT bout in normoxia.
- Conditions
- Ketosis, Hypoxia, Angiogenesis
- Trial name
- NCT06472427
- Testing
- Normoxic recovery and ketones (NKE), Hypoxic recovery and ketones (HKE)
- Where
- Belgium
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Muscle; Fatigue, Heart, Skeletal Muscle Recovery
Infrared Low-level Laser Therapy Before Intense Progressive Running Test of High-level Soccer Players
Photobiomodulation therapy (PBMT) has recently been used to alleviate postexercise muscle fatigue and enhance muscle recovery, demonstrating positive results.
- Trial name
- NCT03803956
- Testing
- Active PBMT
- Where
- Brazil
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Post-exercise Muscle Recovery
Phototherapy and Cryotherapy in Post-exercise Skeletal Muscle Recovery
Volunteers were divided randomly in five experimental groups. VAS (Visual Analogic scale) to measure DOMS (Delayed Onset Muscle Soreness) and blood samples was taken before any procedure.
- Trial name
- NCT02622971
- Testing
- PBMT, Cryotherapy
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Statin Adverse Reaction
Exercise Intensity and Muscle Recovery in Statin Users
This study aims to investigate how different types and intensities of exercise affect muscle recovery in individuals taking statin medications compared to healthy controls.
- Trial name
- STN-EX (NCT07563452)
- Testing
- Dose-Escalation Exercise Protocol
- Where
- Austria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Raffaele Mazzolari
Skeletal Muscle Hypertrophy
Post-exercise Recovery After Dietary Protein Ingestion in Healthy Young Men (Meat-Milk Study)
Rationale: The consumption of dietary protein immediately after exercise is necessary to maximally stimulate muscle protein synthesis rates (24, 37). Recent work suggests that the type of protein consumed (e.g., animal vs.
- Trial name
- Meat-Milk (NCT01578590)
- Testing
- Lean minced meat (beef)
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Muscle Damage, Healthy
Exploring Muscle Breakdown During Exercise Recovery
This study will allow researchers to explore how muscle responds to heavy exercise. The researchers will characterise rates of muscle protein breakdown and synthesis 24hours after heavy exercise with a post exercise protein…
- Trial name
- EMBER (NCT04841772)
- Testing
- Recover Vegan Protein Supplement
- Where
- United Kingdom
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Cryotherapy Effect
Cold Therapy in the Treatment of Exercise-induced Muscle Damage
Subjects were randomly placed in five groups: (1) single exposure at 5°C in cold water immersion, (2) single exposure at 15°C in cold water immersion, (3) multiple exposures at 10°C in cold water immersion, (4) whole body…
- Trial name
- NCT02341612
- Testing
- single exposure at 5°C in CWI, single exposure at 15°C in CWI, multiple exposures at 10°C in CWI
- Where
- Brazil
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Brasilia
Skeletal Muscle Damage, Muscle Inflammation
Protein Supplementation and Muscle Recovery in Football
Soccer is an intermittent sport including a high number of powerful actions such as accelerations, decelerations, changes of direction, jumps and impacts that incorporate a strong eccentric component and may therefore lead to…
- Conditions
- Skeletal Muscle Damage, Muscle Inflammation, Muscle Recovery, Soccer Performance
- Trial name
- PRO-FOOTBALL (NCT03348267)
- Testing
- Milk protein isolate
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Anterior Cruciate Ligament Reconstruction, Muscular Atrophy
Nutritional Intervention to Enhance Recovery After Arthroscopic Knee Surgery in Adults
Loss of skeletal muscle mass (atrophy) and strength in the lower limb are consequences of elective knee surgery as result of prolonged disuse from limb immobilization and impaired mobility, as well as pathophysiological trauma.
- Trial name
- NCT06233825
- Testing
- Omega-3 Fatty Acids and Essential Amino Acids, Safflower Oil and Non-Essential Amino Acids
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dr. Chris McGlory, PhD
Exercise, Resistance Training
Muscle Response to High Intensity Interval Resistance Training (HIIRT)
Resistance training (RT) is one of the most important stimuli for muscle hypertrophy and it plays an important role on weight loss and fatty acid oxidation increase.
- Trial name
- HIIRT (NCT04321772)
- Testing
- High Intensity Interval Resistance Training, Traditional Resistance Training
- Where
- Italy
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Padova
Muscle Recovery, Muscle Soreness
Effect of PEA on Muscle Recovery Following Resistance Exercise
This study evaluates the effects of short term palmitoylethanolamide (PEA) supplementation on functional responses (i.e. muscle soreness and performance parameters) to strenuous eccentric exercise, and investigateq the systemic…
- Trial name
- NCT05753111
- Testing
- PEA
- Where
- Belgium
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Massage, Inflammatory Response
Comparison of Different Forms of Recovery on the Functionality After Physical Exercise
Delayed onset muscle soreness (DOMS) and decrease of musculoskeletal function are due to high intensity training and / or sports activities. These occur due to micro lesions of muscle tissue resulting in nociceptor sensitization.
- Conditions
- Massage, Inflammatory Response, Muscle, Skeletal, Cryotherapy Effect
- Trial name
- NCT04201977
- Testing
- Foam Roller Recovery, Active recovery, Immersion in cold water
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Santa Maria
Atrophy, Disuse, Atrophy, Muscular
Effects of Resistance Training Preconditioning on Skeletal Muscle Recovery From a Period of Disuse in Young Adults
The goal of this clinical trial is to compare the effects of resistance training (RT) preconditioning vs no training on disuse-induced atrophy and post-disuse resistance training in young healthy individuals.
- Trial name
- NCT05760066
- Testing
- Resistance Training Preconditioning, Control
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Auburn University
Exercise Induced Muscle Damage, Physical Activity
Walk It Off! the Influence of Physical Activity Level on the Recovery from Damaging Resistance Exercise
After completing novel activity or exercise we may experience exercise-induced muscle damage (EIMD), resulting in a period of reduced muscle function and delayed onset muscle soreness (DOMS).
- Conditions
- Exercise Induced Muscle Damage, Physical Activity, Inflammation, Exercise Recovery
- Trial name
- WIO (NCT06810271)
- Testing
- Eccentric resistance exercise
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Healthy
Effect of a Nutritional Supplement on Muscle Recovery
The aim is to develop a food supplement drink that supports muscle health by combining specific fatty acids, which can positively affect metabolic and inflammation processes that are important for muscle health.
- Trial name
- RECOVER (NCT07586839)
- Testing
- Control drink, Vegan supplement containing caprylic acid and omega-3 fatty acids
- Where
- Netherlands
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Muscle Recovery
Vegan or Animal Protein Ingestion on the Recovery of Muscle Function Following Exercise
This study will assess the effect of daily post-exercise vegan (pea) and animal (whey) protein ingestion compared to placebo over 7 days of recovery from strenuous exercise.
- Trial name
- VAMPIRE (NCT04156386)
- Testing
- Recovery animal (20g whey) protein supplement, Recover vegan (26g pea) protein supplement
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Skeletal Muscle Damage
Recovery Kinetics Following Change of Direction Training
This study aims at investigating the recovery kinetics of skeletal muscle damage, neuromuscular fatigue and performance following a single change of direction (COD) training session in competitive soccer players.
- Trial name
- NCT04795232
- Testing
- COD45, COD90
- Where
- 2 sites in Greece
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Skeletal Muscle Damage
Recovery Kinetics Following a Soccer Training in Middle-aged Males
This study aims at investigating the recovery kinetics of skeletal muscle damage, neuromuscular fatigue and performance following a single soccer trainning session in middle aged males.
- Trial name
- NCT06260215
- Testing
- ST
- Where
- Greece
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Skeletal Muscle Damage, Exercise-induced Aseptic Inflammation
Aloe Vera Ointment Application and Skeletal Muscle Recovery
Aloe vera, sometimes described as pharmaceutical aloe, is a flowering succulent plant with many therapeutic properties such as wound and burn wound healing, treatment of diabetes and reduction of blood lipid profile.
- Conditions
- Skeletal Muscle Damage, Exercise-induced Aseptic Inflammation, Performance
- Trial name
- NCT03934762
- Testing
- Natural Aloe Vera, Aloe vera soup
- Where
- Greece
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Healthy
The Effect of Protein Ingestion on the Recovery of Skeletal Muscle Function Following Eccentric Exercise.
The present study will assess the effect of the type and timing of protein ingestion 6 days prior to, and 7 days following eccentric exercise on the time course of 1) the recovery of muscle function, 2) the recovery of perceived…
- Trial name
- SPADE (NCT02980900)
- Testing
- Post exercise protein-polyphenol supplement, Pre bed protein-polyphenol supplement
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Exeter