Clinical trials: Skin Cancer Healing
Wound Healing, Surgical Wound
Evaluating rhPDGF-BB-Enhanced Wound Matrix for Head and Neck Reconstruction
Skin cancers such as basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and melanoma lesions that develop on the head and neck are treated by Mohs surgery or wide local excision to remove all tumor cells and preserve the…
- Trial name
- NCT06634030
- Testing
- RhPDGF-BB, Saline
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Vanderbilt University Medical Center
Skin Carcinoma
A Disposable Negative Pressure Wound Therapy Device (SNaP) to Promote Wound Healing in the Lower Limbs Following Mohs Micrographic Surgery for Non-melanoma Skin Cancer
This clinical trial studies whether a disposable negative pressure wound therapy (dNPWT) device, SNaP Wound Care System (Ultraportable Mechanically Powered Negative Pressure Wound Therapy) (SNaP), promotes wound healing in the…
- Trial name
- NCT07032701
- Testing
- Best Practice, Educational Intervention, Electronic Health Record Review
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Dupuytren's Contracture
Evaluation of the Efficiency of Autologous Platelet Gel (Platelet Rich Fibrin) Obtained From Own Patients' Blood Versus Vaselitulle in Dupuytren's Disease Postoperative Wound Healing
This study is a clinical, multicentric, randomised open trial. The objective is to evaluate the efficiency, in terms of wound healing speed, of peroperative application of autologous platelets gel versus standardized wound…
- Trial name
- NCT00931567
- Testing
- Autologous platelets gel, Vaselitulle
- Where
- 2 sites in France
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Body Mass Index Greater Than or Equal to 30, Malignant Breast Neoplasm
Negative Pressure Wound Therapy in Healing Abdominal Incision in Obese Patients Undergoing Breast Reconstruction Surgery
This trial studies the safety and how well negative pressure wound therapy works in healing the abdominal incision in obese patients undergoing free flap breast reconstruction surgery.
- Conditions
- Body Mass Index Greater Than or Equal to 30, Malignant Breast Neoplasm, Mammoplasty Patient, Obesity
- Trial name
- NCT04003038
- Testing
- Negative Pressure Wound Therapy, Wound Care Management
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- M.D. Anderson Cancer Center
Ulcer, Wounds and Injuries
Analgesia and Wound Healing Assessment Following Topical Morphine Applied to Patients With Cutaneous Cancer Related Pain
Cutaneous cancer-related pain is difficult to treat. These patients are often prescribed high systemic dosages of opioids. Yet, many patients continue to report pain while experiencing dose-limiting side effects.
- Trial name
- NCT00306020
- Testing
- topical morphine
- Sponsor
- Soroka University Medical Center
Wound of Skin, Non-melanoma Skin Cancer
Efficacy and Safety of a Nanofat-seeded Biological Scaffold in Healing Lower Limb Surgical Defects
Large full-thickness skin defects, such as those resulting from trauma, large and giant congenital nevi, disfiguring scars, or tumor resection remain major clinical problems to patients and physicians.
- Conditions
- Wound of Skin, Non-melanoma Skin Cancer, Skin Graft Complications, Wound of Lower Leg
- Trial name
- NCT03548610
- Testing
- Nanofat-seeded biological scaffold on surgical defect
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Breast Cancer
Healing Touch, Quality of Life, and Immunity During Breast Cancer Treatment
The purpose of this research study is to understand effects of a complementary medicine therapy, Healing Touch on quality of life and immunity of patients who are receiving treatment for breast cancer.
- Trial name
- NCT00565305
- Testing
- Healing Touch, Standard Treatment
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Iowa
Scar, Skin Scarring
Scar Appearance After Postoperative Hydrocolloid Dressing Versus Standard Petrolatum Ointment
Patients will be randomized either to receive standard daily dressing or hydrocolloid dressing using a randomization generator. After closing the wound with the sutures,the scar will be covered by a hydrocolloid dressing, which…
- Conditions
- Scar, Skin Scarring, Skin Cancer, Wound Heal
- Trial name
- NCT05618912
- Testing
- Hydrocolloid dressing, Petrolatum jelly dressing
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Indiana University
Scar, Breast Neoplasms
Aesthetic Effect of Steri-Strip Orientation on Healing and Scar Appearance in Breast Surgery
All patients undergoing breast biopsy, lumpectomy, needle-localization-guided breast biopsy, and mastectomy at Einstein Medical Center Philadelphia, Einstein Medical Center Montgomery, Center One, or Einstein Elkins Park will be…
- Conditions
- Scar, Breast Neoplasms, Breast Diseases, Surgical Wound
- Trial name
- NCT04554316
- Testing
- Steri-strip
- Where
- 2 sites in United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Albert Einstein Healthcare Network
Radiodermatitis, Oncology
Jalosome® Soothing Gel Efficacy Grade 2 or 3 Radiodermatitis.
Testing the efficacy of the Jalosome® Soothing gel in 2 or 3 grade radiodermatitis healing in oncological patients. The investigators would like to know also the efficacy of the device on quality of life and pain.
- Conditions
- Radiodermatitis, Oncology, Quality of Life, Pain
- Trial name
- NCT04692389
- Testing
- Jalosome soothing gel
- Where
- Switzerland
- Sponsor
- Welcare Industries SpA
Acute Radiation Dermatitis, Head and Neck Cancer (H&N)
Effectiveness of 0.9% Normal Saline Soaking in Managing Acute Radiation Dermatitis
The goal of this clinical trial is to learn if normal saline soaks can reduce the severity of acute radiation dermatitis in patients with sarcomas or head and neck cancer receiving radiotherapy.
- Conditions
- Acute Radiation Dermatitis, Head and Neck Cancer (H&N), Sarcomas
- Trial name
- NCT07553260
- Testing
- Normal Saline Soaks (0.9% Sodium Chloride)
- Where
- Jordan
- Volunteers
- 150 people
- Sponsor
- King Hussein Cancer Center
Neoplasm Metastasis, Secondary Malignant Neoplasm of Lymph Node
Negative Pressure Wound Therapy in Groin Dissection
This study investigates the use of a negative pressure wound therapy device (PICO™, Smith \& Nephew Healthcare, UK) on clean, closed surgical wounds, in patients who are undergoing inguinal lymphadenectomy for metastatic…
- Conditions
- Neoplasm Metastasis, Secondary Malignant Neoplasm of Lymph Node, Non-healing Surgical Wound (Disorder), Skin Neoplasms
- Trial name
- NCT02408835
- Testing
- PICO™
- Where
- United Kingdom
- Volunteers
- 22 people
- Sponsor
- South Eastern Health and Social Care Trust
Non-melanoma Skin Cancer
Healing Effects of HP802-247 Versus Antibiotic Ointment in Mohs Micrographic Surgery Patients
This study compares HP802-247 versus an antibiotic ointment for healing the wound after Mohs surgery.
- Trial name
- NCT01359735
- Testing
- HP802-247, Bacitracin Ointment
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Healthpoint
Skin Tags
Randomized Clinical Trial on Skin Tags Approachment.
Skin tags are a benign dermal disease very frequent in the general population. Their exeresis is indicated in case of discomfort of the affected person (usually because of friction or increase in size).
- Trial name
- HUM_FIB (NCT04161274)
- Testing
- Traditional method: Electrosurgery, Traditional method: Cryotherapy, Traditional method: Silver nitrate
- Where
- Spain
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Breast Neoplasms, Ischemia-Reperfusion Injury
DIEP Flap Breast Reconstruction: Perioperative Biomarkers and Outcomes
Brief Summary This observational study will follow patients who undergo DIEP flap breast reconstruction to better understand a common surgical challenge called ischemia-reperfusion (I/R) injury.
- Conditions
- Breast Neoplasms, Ischemia-Reperfusion Injury, Postoperative Complications, Wound Healing
- Trial name
- NCT07263347
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Hubei Cancer Hospital
Nevus, Seborrheic Keratosis (SK)
Impact of Skin Type on Wonud Healing and Scarring Following Facial Skin Surgery
The goal of this observational study is to learn how an individual's skin type influences the wound healing process and scar formation in Chinese patients undergoing facial dermatologic surgery.
- Conditions
- Nevus, Seborrheic Keratosis (SK), Cyst, Lipoma
- Trial name
- NCT07384299
- Where
- China
- Volunteers
- 173 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Diabetic Foot Ulcer
Efficacy of LL-37 Cream on Bacteria Colonization, Inflammation Response and Healing Rate of Diabetic Foot Ulcers
Diabetic foot ulcer (DFU) is a common complication of diabetes with global prevalence of 6.3%. Treatment of diabetic foot ulcer (DFU) is challenging with disappointing outcome.
- Trial name
- NCT04098562
- Testing
- LL37, Standard Wound Care
- Where
- 3 sites in Indonesia
- Volunteers
- 40 people
- Sponsor
- Fakultas Kedokteran Universitas Indonesia
Breast Cancers, Gynecologic Cancer
The Effect Of Meditation On Quality Of Life In Women With Breast Cancer And Other Gynecological Cancers
Women with breast cancer and other gynecologic cancers often suffer significant distress and disability from their disease. A practice of meditation-based stress reduction and cognitive-affective-behavioral learning may help…
- Trial name
- NCT00248911
- Testing
- Mindfulness based meditation program
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Weill Medical College of Cornell University
Skin Transplantation, Skin Grafting
Lower Extremity Graft Study (LEGS): A Multicentre Randomised Controlled Trial of Negative Pressure Wound Therapy Versus Conventional Dressings for Split-thickness Skin Grafts After Lower Leg Skin Tumour Excision
The goal of this clinical trial is to compare the effect of negative pressure wound therapy (NPWT) versus traditional dressings on the incidence of transplant infection in adult patients undergoing split-thickness skin grafting…
- Conditions
- Skin Transplantation, Skin Grafting, Split Thickness Skin Graft, Negative-Pressure Wound Therapy
- Trial name
- LEGS (NCT07040683)
- Testing
- Negative Pressure Wound Therapy (NPWT), Traditional Dressing
- Where
- Sweden
- Volunteers
- 232 people
- Sponsor
- Region Skane
Wound Healing, Surgical Wound Infection
The Application of Infrared Thermography in the Prediction of Skin Healing in Surgery
This study investigates whether infrared thermography, a harmless and non-invasive thermal camera technique, can help monitor how surgical wounds heal after skin surgery.
- Conditions
- Wound Healing, Surgical Wound Infection, Postoperative Complications, Skin Neoplasms
- Trial name
- THERMS (NCT07524062)
- Testing
- Infrared thermography
- Where
- Belgium
- Volunteers
- 120 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven