Clinical trials: Skin Diseases, Bacterial
Buruli Ulcer, Mycobacterium Ulcerans Disease
Pathogenesis and Management of M. Ulcerans Disease, Buruli Ulcer
Buruli ulcer is a neglected tropical disease caused by infection with Mycobacterium ulcerans (Mu) in rural parts of West Africa. It causes large skin ulcers mainly in children aged 5 to 15 years.
- Trial name
- Buruli_Path (NCT02153034)
- Where
- 3 sites in Ghana
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Kwame Nkrumah University of Science and Technology
Staphylococcal Infection
Uncomplicated Skin and Soft Tissue Infections Caused by Community-Associated Methicillin-Resistant Staphylococcus Aureus
The purpose of this clinical trial is to evaluate 2 different antibiotics, drugs that fight bacteria, [clindamycin (CLINDA) and trimethoprim-sulfamethoxazole (TMP-SMX)] and wound care for the outpatient management of…
- Trial name
- NCT00730028
- Testing
- Trimethoprim-sulfamethoxazole, Clindamycin
- Where
- 6 sites in United States
- Volunteers
- 1,310 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Infectious Skin Diseases, Bacterial Skin Diseases
Safety and Efficacy Study of Oxazolidinones to Treat Uncomplicated Skin Infections
The purpose of this study is to assess the efficacy, safety and tolerability of RX-1741, an oxazolidinone, versus linezolid, another oxazolidinone, in the treatment of uncomplicated skin and skin structure infections
- Conditions
- Infectious Skin Diseases, Bacterial Skin Diseases, Staphylococcal Skin Infections, Streptococcal Infections
- Trial name
- NCT00646958
- Testing
- Radezolid, Linezolid
- Where
- 19 sites in United States
- Volunteers
- 150 people
- Sponsor
- Melinta Therapeutics, Inc.
Onychomycosis
Pilot Study to Evaluate Plasma Treatment of Onychomycosis
The purpose of this study is to evaluate the safety of treating human toenails with atmospheric plasma (MOE Antimicrobial Plasma Treatment System) and get an initial evaluation of the efficacy of this treatment for toenail fungus…
- Trial name
- NCT01819051
- Testing
- MOE Antimicrobial Plasma Treatment System
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Moe Medical Devices
Hidradenitis Suppurativa
A Study of LAD191 in Adults With Hidradenitis Suppurativa
The main purpose of this study is to assess the efficacy of multiple dosing regimens of LAD191 compared to placebo in participants with moderate-to-severe Hidradenitis Suppurativa (HS) and to access the safety, tolerability…
- Trial name
- NCT07151937
- Testing
- LAD191, Adalimumab
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Almirall, S.A.
Skin Infections, Bacterial
Topical SB-275833 Ointment, 1% For The Treatment Of Impetigo
The goal of this study is to determine if topical SB-275833 ointment, 1% is as safe and effective as topical sodium fusidate ointment, 2% for the treatment of impetigo in adults and children as young as 9 months of age.
- Trial name
- NCT00133874
- Testing
- SB-275833 ointment, 1%
- Where
- 69 sites in Canada, Costa Rica and 8 more
- Volunteers
- 520 people
- Sponsor
- GlaxoSmithKline
Skin Diseases, Bacterial
Study Comparing the Safety and Efficacy of Tigecycline With Ampicillin-Sulbactam or Amoxicillin-Clavulanate to Treat Skin Infections
The purpose of this study is to compare the safety and efficacy of the antibiotic tigecycline with other antibiotics, ampicillin-sulbactam, and amoxicillin-clavulanate in the treatment of a complicated skin and/or skin structure…
- Trial name
- NCT00368537
- Testing
- Tigecycline, ampicillin-sulbactam
- Where
- 57 sites in United States, Canada and 10 more
- Volunteers
- 550 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Atopic Dermatitis, Dermatology
A Prospective, Observational Study of Clinician and Patient-reported Outcomes in Patients With Dermatological Conditions
The primary goal of the study is to collect standardized patient and clinician reported outcome measures for patients diagnosed with a range of dermatological conditions in an academic clinical practice setting.
- Conditions
- Atopic Dermatitis, Dermatology, Vitiligo, Alopecia Areata
- Trial name
- ClinPRO-DERM (NCT05084417)
- Testing
- N/A This is an observational study
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- OM1, Inc.
Staphylococcal Skin Infections, Streptococcal Infections
Evaluation of Penetration of Ceftobiprole Into Soft Tissue Determined by Microdialysis in Healthy Volunteers
The primary objective of this study is to measure the penetration of ceftobiprole into subcutaneous (s.c.) adipose tissue and skeletal muscle and to determine the concentration over time of ceftobiprole in these tissues and in…
- Trial name
- NCT01026740
- Testing
- Ceftobiprole
- Volunteers
- 15 people
- Sponsor
- Basilea Pharmaceutica
Fungal Infection, Onychomycosis
Topical Amphotericin B in 30% Dimethylsulphoxide in Treating of Non-dermatophytes Onychomycosis
The randomized control trial study aimed to evaluate effectiveness and safety of amphotericin B in 30% DMSO solution comparing with 30% DMSO solution in NDMs onychomycosis treatment.
- Conditions
- Fungal Infection, Onychomycosis, Fungus, Nail
- Trial name
- amphotericin (NCT03814343)
- Testing
- amphotericin B in 30% DMSO, 30% DMSO
- Where
- Thailand
- Volunteers
- 19 people
- Sponsor
- Mahidol University
DFU, VLU
BIO-SEE: Bioburden Imaging Outcome Study for Equivalence Evaluation
The study aims to demonstrate the substantial equivalence of the cureVision cV system's performance in detecting moderate to high bacterial loads in direct comparison to the comparator device for fluorescence imaging in wounds…
- Conditions
- DFU, VLU, Surgical Wound, Wounds
- Trial name
- NCT07611318
- Testing
- cureVision cV
- Where
- 5 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Capsicure, LLC
Hidradenitis Suppurativa
Trial Comparing Efficacy of Treatments for Hidradenitis Suppurativa
The purpose of this research study is to further evaluate the efficacy of two treatment regimens for the treatment of hidradenitis suppurativa. This is a randomized controlled study.
- Trial name
- NCT01063270
- Testing
- Clindamycin & Rifampin, Clindamycin + Rifampin along with NdYag Laser treatment
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Henry Ford Health System
Tinea Pedis
Non-inferiority Trial of Dapaconazole Versus Ketoconazole
The main purpose of this study is to demonstrate that dapaconazole cream 2% (experimental drug) is non-inferior to ketoconazole cream 2% (Nizoral® - active comparator) for the treatment of dermatological lesions of Tinea pedis…
- Trial name
- NCT03320486
- Testing
- Dapaconazole, Ketoconazole
- Where
- Brazil
- Volunteers
- 360 people
- Sponsor
- Biolab Sanus Farmaceutica
Interdigital Tinea Pedis
Clinical Equivalence of Two Generic Butenafine Hydrochloride 1% Creams as Compared to Lotrimin Ultra Cream in Patients With Interdigital Tinea Pedis
To demonstrate comparable safety and efficacy of Taro Pharmaceuticals, Inc butenafine hydrochloride cream 1% test product and Lotrimin Ultra cream (reference listed drug) in the treatment of interdigital tinea pedis, and to show…
- Trial name
- BNF-0909 (NCT01119742)
- Testing
- Butenafine Hydrochloride 1%, Butenafine Hydrochloride 1% B, Vehicle A
- Volunteers
- 428 people
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Tinea Pedis
Study With Nåva Foot Cream in Patients With Tinea Pedis Interdigitalis
A prospective, open post-market clinical investigation that will enroll male and female subjects diagnosed with foot fungus and at least one of the following conditions: heal cracks, calluses and/or dry feet.
- Trial name
- NCT03676686
- Testing
- Nåva Foot Cream
- Where
- 3 sites in Sweden
- Volunteers
- 46 people
- Sponsor
- Natumin Pharma AB
Dengue, Chikungunya
Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health Perspective
RACSMEI addresses the high burden of infectious diseases in low- and middle-income countries, including Cambodia, where limited surveillance and laboratory capacity often obscure etiologies and transmission dynamics.
- Conditions
- Dengue, Chikungunya, Zika Virus Infection, Japanese Encephalitis
- Trial name
- RACSMEI (NCT07358910)
- Where
- Cambodia
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur du Cambodge
Onychomycosis of Toenail
An Internet Mediated Research Study to Assess the Quality of Life of Consumers With Self-reported Fungal Nail Infection (Onychomycosis) During Treatment With Scholl Fungal Nail.
To evaluate the effect on quality of life of consumers with self-reported onychomycosis during the first 4 weeks of treatment in relation to the appearance of the infected toenail.
- Trial name
- NCT04084782
- Testing
- Fungal Nail Treatment Kit
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
Tinea Capitis
A Study Of Diflucan In Children With Ringworm Of The Scalp
The purpose of this study is to evaluate the safety and efficacy of fluconazole for the treatment of tinea capitis in pediatric patients aged 3 to 12 years.
- Trial name
- NCT00645242
- Testing
- fluconazole
- Where
- 31 sites in United States, Puerto Rico
- Volunteers
- 185 people
- Sponsor
- Pfizer
Cellulitis, Abscess
Decreasing Antibiotic Duration for Skin and Soft Tissue Infection Using Behavioral Economics in Primary Care
Study the efficacy of a package of behavioral economics strategies (versus an education-only control condition) in altering clinician behavior regarding antibiotic prescription duration for skin and soft tissue infection (SSTI).
- Conditions
- Cellulitis, Abscess, Drain Abscess, Impetigo
- Trial name
- SSTIBE (NCT05226260)
- Testing
- Default Duration order Panel
- Where
- United States
- Volunteers
- 1,634 people, healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Skin Lesions, Melanocytic Nevi
Evaluating an Artificial Intelligence Tool to Help Primary Care Doctors Diagnose Skin Conditions.
This study aims to determine if an artificial intelligence (AI) medical device can help primary care doctors more accurately identify and manage various skin conditions.
- Conditions
- Skin Lesions, Melanocytic Nevi, Melanoma (Skin Cancer), Basal Cell Carcinoma of Skin
- Trial name
- LegitHealth PH (NCT07428941)
- Testing
- AI-based medical device for aided diagnosis in dermatological conditions
- Where
- Spain
- Volunteers
- 9 people
- Sponsor
- AI Labs Group S.L