Clinical trials: Skin Diseases, Papulosquamous
Plaque Psoriasis
A Phase 2 Dose Ranging, Evaluator-Blinded Study to Evaluate the Safety of Topical IDP-118
Subjects with a clinical diagnosis of plaque psoriasis with 10% to 20% of body surface area affected will be enrolled in the study.
- Trial name
- IDP-118 (NCT01670513)
- Testing
- IDP-118 Low Strength, IDP-118 High Strength
- Where
- 6 sites in United States
- Volunteers
- 60 people
- Sponsor
- Dow Pharmaceutical Sciences
Psoriasis
Prediction Model for Osteopenia in Patients With Psoriasis
This study aims to develop a clinical prediction model for osteopenia in patients with psoriasis. By retrospectively analyzing demographic, laboratory, and lifestyle variables, the investigators will identify risk factors…
- Trial name
- NCT07112755
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Chongli Yu
Plaque Psoriasis
Study to Assess the Reliability of PASI Scoring Using Digital-Based Images
This is an open-labeled study to evaluate the reliability of digital photographs for the remote assessment of the disease severity of plaque psoriasis.
- Trial name
- NCT05835843
- Testing
- In-Person and Remote Disease Assessment
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- Innovaderm Research Inc.
Rheumatoid Arthritis (RA), Atopic Dermatitis (AD)
A Study of Oral Upadacitinib (RINVOQ) Tablets to Assess Adverse Events and Change in Disease Symptoms in Korean Participants With Moderate to Severe Active Rheumatoid Arthritis, Atopic Dermatitis, Ankylosing Spondylitis or Psoriatic Arthritis
Rheumatoid Arthritis (RA) is an inflammatory disease of the joints characterized by the swelling of multiple joints and tenderness caused by progressive inflammatory synovitis, which leads to serious and debilitating diseases.
- Conditions
- Rheumatoid Arthritis (RA), Atopic Dermatitis (AD), Ankylosing Spondylitis (AS), Psoriatic Arthritis (PsA)
- Trial name
- NCT04541810
- Where
- 116 sites in South Korea
- Volunteers
- 2,369 people
- Sponsor
- AbbVie
Psoriasis
Anti-psoriatic Effect of TL01 Light Therapy
This is a pilot study to investigate the effect of TL01 narrow band UVB therapy on the resident dermal dendritic cells characterized by expression of CD1c and CD141.
- Trial name
- NCT02599415
- Testing
- TL01 light treatment
- Where
- United Kingdom
- Volunteers
- 6 people
- Sponsor
- University of Aberdeen
Skin and Connective Tissue Diseases
A Psoriasis Plaque Test Trial With LEO 90100 Compared to Betesil® in Patients With Psoriasis Vulgaris
The purpose of this study is to evaluate the anti-psoriatic effect of LEO 90100 aerosol foam compared with Betesil® medicated plaster
- Trial name
- NCT02518048
- Testing
- LEO 90100 Aerosol foam, Betesil® 2.25 mg
- Where
- France
- Volunteers
- 35 people
- Sponsor
- LEO Pharma
Osteoarthritis, Rheumatoid Arthritis
Web-based Support to Manage Arthritis Pain
Development of an interactive, online pain self-management program for adults who suffer from pain associated with osteoarthritis, rheumatoid arthritis, Ankylosing spondylitis, and other arthritic conditions (e.g., psoriatic…
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Ankylosing Spondylitis, Other Arthritic Conditions (e.g., Psoriatic Arthritis)
- Trial name
- NCT01463189
- Testing
- painACTION: Arthritis
- Where
- United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Inflexxion, Inc.
Psoriatic Arthritis, Enthesitis
Ultrasound and Shear Wave Elastography Assessment of Entheses in Psoriatic Arthritis
Psoriatic arthritis (PsA) is a chronic inflammatory disease that frequently involves the entheses, where tendons, ligaments, and fascia insert into bone.
- Trial name
- SWE-PsA (NCT07785089)
- Testing
- Grayscale Ultrasonography, Power Doppler Ultrasonography, and Shear Wave Elastography
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Marmara University
Psoriasis
Tight Control Dose Reductions of Biologics in Psoriasis Patients With Low Disease Activity
Rationale/hypothesis: Moderate-to-severe psoriasis can be treated with biologics. Objective To investigate whether the dose of biologics can be reduced in patients with psoriasis with stable disease.
- Trial name
- NCT02602925
- Testing
- Dose decrease, Usual care
- Where
- 6 sites in Netherlands
- Volunteers
- 120 people
- Sponsor
- Radboud University Medical Center
Acne, Atopic Dermatitis
Collection of Samples From Subjects With Various Skin Conditions and Healthy Volunteers
The purpose of the study is to collect different samples for molecular characterization of inflammatory skin diseases.
- Conditions
- Acne, Atopic Dermatitis, Chronic Hand Eczema, Hidradenitis Suppurativa
- Trial name
- NCT05994976
- Testing
- Blood samples collection, Oral samples collection, Hair samples collection
- Where
- Canada
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Innovaderm Research Inc.
Ankylosing Spondylitis, Arthritis, Psoriatic
Study Evaluating the Safety of Etanercept in Rheumatoid Arthritis, Ankylosing Spondylitis and Psoriatic Arthritis
This is a Phase 4 open label, non-interventional, multi-center study to evaluate the safety of Enbrel (etanercept) treatment in patients receiving etanercept 25mg sc twice weekly or 50mg of etanercept once weekly.
- Conditions
- Ankylosing Spondylitis, Arthritis, Psoriatic, Arthritis, Rheumatoid, Spondylitis, Ankylosing
- Trial name
- NCT00273858
- Testing
- There is no Intervention. The study is observational.
- Where
- 9 sites in Greece
- Volunteers
- 880 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Psoriasis
Pilot Studies Testing Levels of P63 in Psoriasis Skin Lesions
The purpose of this study is to understand the role of a specific protein, tumor protein p63 in the skin disease psoriasis. This study is to further understand how psoriasis lesions happens.
- Trial name
- NCT04560647
- Testing
- No intervention - Psoriasis Subject, No intervention - Control Subject
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Wright State University
Oral Lichen Planus
The Therapeutic Effect of Curcumin in Nanogels Compared to 0.1% FAO in the Management of Oral Lichen Planus
This randomized, double-blind clinical trial evaluates the therapeutic effects of curcumin in nanogels compared to 0.1% fluocinolone acetonide oral paste in the management of atrophic-erosive oral lichen planus (OLP).
- Trial name
- NCT06932848
- Testing
- Curcumin in Nanogels, 0.1% Fluocinolone Acetonide Oral Paste
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Chulalongkorn University
Psoriasi
Effect of Adalimumab Therapy on Psoriasis Patient
to evaluate the impact of adalimumab therapy on quality of life in patient with severe psoriasis.
- Trial name
- NCT05889338
- Testing
- adalimumab and methotrexate
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Sohag University
Psoriasis
Long-Term One Year Use of Alefacept (Amevive®) in Moderate to Severe Chronic Plaque Type Psoriasis
The purpose of this research study is to see how well the medication Alefacept (Amevive®) works for continuous treatment of chronic plaque psoriasis.
- Trial name
- NCT00655564
- Testing
- Alefacept
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Wake Forest University
Psoriasis
VTX958 Versus Placebo for the Treatment of Moderate to Severe Psoriasis
This is a study to understand if taking VTX958 is safe and effective in participants diagnosed with moderate to severe psoriasis (PsO).
- Trial name
- Serenity PsO (NCT05655299)
- Testing
- VTX958 Dose A, VTX958 Dose B, VTX958 Dose C
- Where
- 63 sites in United States, Canada and 1 more
- Volunteers
- 222 people
- Sponsor
- Ventyx Biosciences, Inc
Psoriasis, Cardiovascular Diseases
Cardiovascular Risk Predictors in Patients With Psoriasis
The investigators are planning to find the right modification of traditionally used risk scores (PASI, DLQI) in patients with psoriasis of different severity to guide the treatment that could potentially extend life, improve…
- Trial name
- NCT05200598
- Where
- Russia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Psoriasis
Risankizumab Long-term Remission Study
Although the newly developed biologics (drugs derived from living cells cultured in a laboratory) are highly effective in controlling psoriasis, all the biologics should be continuously injected to suppress recurrence of the…
- Trial name
- NCT04630652
- Testing
- Risankizumab-Rzaa, Punch biopsies of the skin at baseline visit, Punch biopsies of the skin at week 28 visit
- Where
- 3 sites in United States
- Volunteers
- 24 people
- Sponsor
- Jaehwan Kim
Arthritis, Psoriatic
A Study of Guselkumab in Participants With Active Psoriatic Arthritis
The purpose of this study is to evaluate the efficacy of guselkumab treatment in participants with active psoriatic arthritis (PsA) by assessing the reduction in signs and symptoms of PsA.
- Trial name
- APEX (NCT04882098)
- Testing
- Guselkumab
- Where
- 280 sites in United States, Australia and 27 more
- Volunteers
- 1,054 people
- Sponsor
- Janssen Research & Development, LLC
Rheumatoid Arthritis, Psoriatic Arthritis
A Study in Pregnant Women With Chronic Inflammatory Diseases Treated With Cimzia (Certolizumab Pegol)
The purpose of the study is to assess systemic certolizumab pegol (CZP) exposure, the formation of anti-CZP antibodies and safety of CZP across the course of pregnancy in study participants with chronic inflammatory diseases.
- Conditions
- Rheumatoid Arthritis, Psoriatic Arthritis, Crohn's Disease, Axial Spondyloarthritis
- Trial name
- CHERISH (NCT04163016)
- Testing
- Pharmacokinetics of certolizumab pegol
- Where
- 9 sites in United States, France and 4 more
- Volunteers
- 22 people
- Sponsor
- UCB Biopharma SRL
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