Clinical trials: Skin Diseases, Papulosquamous
Psoriasis
Levels of Pigment Epithelium-derived Factor in Patients With Psoriasis.
Psoriasis is an immune-mediated chronic inflammatory skin disease associated with increase interaction of inflammatory mediators like adipokines.
- Trial name
- NCT05252741
- Testing
- serum samples and punch skin biopsies
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Sohag University
Psoriasis
Safety and Efficacy of Adalimumab to Methotrexate and Placebo in Subjects With Moderate to Severe Chronic Plaque Psoriasis
Placebo-Controlled Study Comparing the Safety and Efficacy of Adalimumab to Methotrexate and Placebo in Subjects with Moderate to Severe Chronic Plaque Psoriasis
- Trial name
- CHAMPION (NCT00235820)
- Testing
- adalimumab, MTX
- Where
- United States
- Volunteers
- 271 people
- Sponsor
- Abbott
Psoriasis
A Study to Evaluate Remicade (Infliximab) in Moderate-to-Severe Chronic Plaque Psoriasis in the Middle Eastern Population (Study P04528)
Middle Eastern subjects with moderate-to-severe chronic plaque psoriasis will be administered infusions of infliximab (Remicade) at 5 mg/kg of body weight at Weeks 0, 2, 6, 14, and 22.
- Trial name
- NCT00687362
- Testing
- Infliximab
- Volunteers
- 22 people
- Sponsor
- Merck Sharp & Dohme LLC
Psoriasis
Study Evaluating The Safety And Tolerability Of ILV-094 In Subjects With Psoriasis
The purpose of this study is to assess safety, and tolerability of multiple doses of ILV-094 administered to subjects with psoriasis
- Trial name
- NCT00563524
- Testing
- ILV-094
- Where
- 24 sites in United States, Canada and 2 more
- Volunteers
- 76 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Psoriasis
Phase 4 Multicenter, Open-label Study on Efficacy and Safety of Apremilast in Moderate-to-severe Psoriasis
This study aims to evaluate the efficacy and safety of Apremilast tablets in patients with psoriasis over 32 weeks, through a multicenter, single-arm, open-label, phase 4 clinical trial.
- Trial name
- NCT07190391
- Volunteers
- 425 people
- Sponsor
- Daewoong Pharmaceutical Co. LTD.
PsA Patients Fulfilling CASPAR Criteria in Remission
Disparity Between Ultrasound- and Clinical Findings in Psoriatic Arthritis in Remission
Comparison of the proportion of Psoriatic arthritis patients in ultrasound remission (i.e. no power Doppler synovitis, tenosynovitis, dactylitis, enthesitis, PD=0) depending on whether patient and physician's global assessment of…
- Trial name
- PARURE (NCT03396679)
- Testing
- Ultrasound examination
- Where
- France
- Volunteers
- 62 people
- Sponsor
- University Hospital, Montpellier
Psoriasis
Topically Applied IDP-118 Lotion and HP Monad Lotion in Subjects With Moderate to Severe Plaque Psoriasis
Suppression Potential of Topically Applied IDP-118 Lotion and HP Monad Lotion in Subjects with Moderate to Severe Plaque Psoriasis.
- Trial name
- NCT03058744
- Testing
- IDP-118 Lotion, HP Monad Lotion, Ultravate Cream
- Where
- 12 sites in United States
- Volunteers
- 94 people
- Sponsor
- Bausch Health Americas, Inc.
Psoriasis
Excimer Laser Phototherapy Outcomes in the Treatment of Psoriasis
The purpose of this study is to determine the best dosing strategy when using Excimer Laser to treat plaque-type psoriasis. In this study, half of the body's psoriasis will be treated with a new dosing strategy, and the other…
- Trial name
- Photos (NCT02294981)
- Testing
- Excimer laser phototherapy
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of California, San Francisco
Oral Lichen Planus, Oral Cancer
Malondialdehyde and Nitrous Oxide as Salivary Biomarkers for Different Oral Lesions
investigating the level of malondialdehyde (MDA) \& nitric oxide (NO) in saliva in oral premalignant and malignant lesions in order to determine their diagnostic value for the malignant and potentially malignant lesions.
- Conditions
- Oral Lichen Planus, Oral Cancer, Leukoplakia, Oral Keratoses
- Trial name
- NCT04267419
- Testing
- salivary biomarker
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Beni-Suef University
Alopecia Areata, Alopecia Totalis
The Epidemiology, Management and Comorbidities in Alopecia Areata in Czech Republic
The study series consists of three studies with the aim to assess the incidence, prevalence, risk factors, comorbidities and management of patients with alopecia areata in Czech Republic based on the patients and registry of a…
- Conditions
- Alopecia Areata, Alopecia Totalis, Alopecia Universalis, Alopecia Areata (& Ophiasis)
- Trial name
- NCT05098600
- Testing
- Exposure of interest
- Where
- Czechia
- Volunteers
- 123 people
- Sponsor
- Faculty Hospital Kralovske Vinohrady
Palmoplantaris Pustulosis
A Placebo-Controlled Double-Blind Study on the Safety and Efficacy of Etanercept in Palmoplantar Pustulosis
Palmoplantar pustulosis (PPP) is a chronic recurrent skin condition characterized by the presence of pustules, erythema and hyperkeratosis on palms and soles.
- Trial name
- NCT00353119
- Testing
- Etanercept
- Where
- 3 sites in Canada
- Volunteers
- 15 people
- Sponsor
- Innovaderm Research Inc.
Rheumatoid Arthritis, Ankylosing Spondylitis
Post-marketing Observational Study to Evaluate the Incremental Impact of AbbVie's Patient Support Program on Patient Reported Outcomes and Health Resource Utilization in Inflammatory Arthritis, Psoriasis and Inflammatory Bowel Diseases in Hungary (VALUE)
The objective of this post-marketing observational study (PMOS) was to evaluate the effectiveness of adalimumab plus the AbbVie Care 2.0 patient support program in participants with rheumatoid arthritis (RA), ankylosing…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Psoriatic Arthritis, Psoriasis
- Trial name
- VALUE (NCT02750800)
- Testing
- Adalimumab, AbbVie Care 2.0
- Volunteers
- 427 people
- Sponsor
- AbbVie
Psoriasis
Study to Assess the Safety and Tolerability of PBF-1650 in Healthy Volunteers.
Single center, randomized, double-blind, placebo-controlled clinical study to assess the safety and tolerability of PBF-1650 in order to obtain the Maximum Tolerated Dose (MTD).
- Trial name
- ADENOIMMUNE (NCT03798236)
- Testing
- PBF-1650 oral capsules
- Where
- Spain
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Palobiofarma SL
Psoriasis
Genomic Study for the Prediction of Efficacy and Adverse Effects of CD11a Monoclonal Antibodies(Raptiva)
The pathogenesis of psoriasis has evolved from epidermal hyperproliferation to immune dysregulation in recent years. A Th1 cytokine profile is universally found is psoriasis.
- Trial name
- NCT00602823
- Volunteers
- 20 people
- Sponsor
- National Taiwan University Hospital
Psoriasis
Enbrel® in Psoriatic Arthritis
This study is testing the effect of etanercept in treating both the skin and joint symptoms of psoriatic arthritis patients. Enbrel®, also known as etanercept, has already been approved by the Federal Food Drug Administration for…
- Trial name
- NCT00111124
- Testing
- Enbrel®
- Sponsor
- Amgen
Psoriasis
Efficacy and Tolerability Study of Topical Ciclosporin in a Psoriasis Plaque Test
Ciclosporin is a cyclic nonribosomal polypeptide of 11 amino acids produced by the fungi Tolypocladium inflatum and Cylindrocarpon lucidum.
- Trial name
- NCT00578370
- Testing
- Ciclosporin 0.5% (Formulation 01B), Ciclosporin 1.5% (Formulation 02B), 0.1% betamethasone
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- ISDIN
Psoriasis, Psoriasis Arthritis
Psoriasis Comorbidities at Hospital Calderón Guardia
The goal of this observational study is to characterize the epidemiologic, clinical, severity, and therapeutic features of patients with psoriasis treated in Costa Rica between 2024 and 2025.
- Conditions
- Psoriasis, Psoriasis Arthritis, Psoriasis (PsO), Psoriasis Patients
- Trial name
- NCT07448337
- Where
- Costa Rica
- Volunteers
- 350 people
- Sponsor
- Caja Costarricense de Seguro Social
Palmoplantar Pustulosis
Picankibart in Palmoplantar Pustulosis
1. Study Design This study is designed as a prospective, single-arm, open-label clinical study. It will be conducted by the Department of Dermatology, the First Affiliated Hospital of Air Force Medical University, and plans to…
- Trial name
- NCT07552454
- Testing
- Picankibart
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xijing Hospital
Fingernail Psoriasis
Dose Response and Safety Study of Topical Methotrexate for the Treatment of Fingernail Psoriasis
The purpose of this clinical study is to compare the efficacy and safety of three concentrations of topical methotrexate for the treatment of fingernail psoriasis.
- Trial name
- NCT00666354
- Testing
- Methotrexate
- Where
- 7 sites in United Kingdom
- Volunteers
- 83 people
- Sponsor
- MediQuest Therapeutics
Rheumatoid Arthritis, Psoriatic Arthritis
Mindfulness Based Stress Reduction in Rheumatic Diseases
This study will assess the mental health and clinical benefits of Mindfulness Based Stress Reduction (MBSR) in patients with rheumatic disease who have anxiety or depression.
- Conditions
- Rheumatoid Arthritis, Psoriatic Arthritis, Scleroderma
- Trial name
- MBSR (NCT03411057)
- Testing
- Mindfulness Based Stress Reduction (MBSR), Control
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Johns Hopkins University
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