Clinical trials: Skin Enhancement
Nephrogenic Systemic Fibrosis, Renal Insufficiency
Evaluation of Nephrogenic Systemic Fibrosis (NSF) in Patients With Chronic Kidney Disease Following OptiMARK Injection
The objective of this study is to prospectively monitor the incidence of adverse drug reactions, specifically NSF during routine use of gadoversetamide in a large number of patients with moderate renal insufficiency (eGFR 30-59)…
- Trial name
- SHERLOC (NCT00811863)
- Where
- United States
- Sponsor
- Guerbet
Breast Cancer
Comparison of Contrast-enhanced Spectral Mammography (CESM) to MRI in Screening High Risk Women for Breast Cancer
This research study is comparing Dual-Energy Contrast-Enhanced Spectral Mammography (CESM) to MRI as a screening tool for breast cancer.
- Trial name
- NCT02275871
- Testing
- MRI, CESM
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Breast Cancer Diagnosis, Breast Cancer Detection
Second-Look Ultrasound Post Contrast-Enhanced Mammography for Additional Lesions Characterization
This study investigates the utility of second-look ultrasound (US) following contrast-enhanced mammography (CEM) to characterize additional lesions detected during routine breast imaging.
- Trial name
- NCT06846814
- Testing
- CEM protocol
- Where
- Italy
- Volunteers
- 350 people
- Sponsor
- Graziella di Grezia
Breast Cancer Screening, Cervical Cancer Screening
Cancer Awareness Among Syrian Migrants
This study aims to develop and evaluate a theory-based educational intervention to improve cancer screening participation among Syrian migrants in Turkey.
- Conditions
- Breast Cancer Screening, Cervical Cancer Screening, Colorectal Cancer Screening, Cancer Prevention Behavior
- Trial name
- NCT07541105
- Testing
- PMT-Based Cancer Screening Educational Intervention, PMT-Based Cancer Screening Education Program
- Volunteers
- 30 people
- Sponsor
- Toros University
Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Triple-Negative Breast Carcinoma
Rintatolimod, Celecoxib and Interferon Alpha 2b With Pembrolizumab For the Treatment of Patients With Metastatic or Unresectable Triple Negative Breast Cancer
This phase I/IIa trial tests the safety, side effects, and best dose of chemokine modulation therapy (CKM) (rintatolimod, celecoxib, and interferon alpha 2b) in combination with pembrolizumab for the treatment of patients with…
- Conditions
- Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Triple-Negative Breast Carcinoma, Unresectable Triple-Negative Breast Carcinoma
- Trial name
- NCT05756166
- Testing
- Biopsy, Biospecimen Collection, Celecoxib
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Roswell Park Cancer Institute
Scar Conditions and Fibrosis of Skin
Dermabrasion for Free Flap Aesthetic Enhancement
The purpose of this study is to evaluate the aesthetic benefit and safety of serial dermabrasion for free flap skin paddles and donor site scars in head and neck reconstruction.
- Trial name
- NCT07233200
- Testing
- Dermabrasion
- Volunteers
- 40 people
- Sponsor
- Milton S. Hershey Medical Center
Skin Graft
Effect of Platelet Rich Plasma and Keratinocyte Suspensions on Wound Healing
This prospective randomized trial evaluated the impact of autologous keratinocytes suspended in platelet concentrates on healing skin graft donor site wounds.
- Trial name
- NCT00856934
- Testing
- Autologous Platelet Rich Plasma, Keratinocyte suspension, Standard dressings
- Where
- Switzerland
- Volunteers
- 45 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Breast Cancer
Multihance Versus Magnevist in Breast MRI
To show if one MRI contrast agent is better than another one in the diagnosis of malignant breast lesions compared to histopathology
- Trial name
- DETECT (NCT00486473)
- Testing
- Multihance, Magnevist
- Where
- Italy
- Volunteers
- 130 people
- Sponsor
- Bracco Diagnostics, Inc
Skin Cancer
SpotCheck: Comparison of Enhanced Telemedicine Versus In-person Evaluation for the Diagnosis of Skin Cancer
The overall goal of this research is to develop a platform that can increase patient access to expert skin cancer diagnostic services via telemedicine.
- Trial name
- NCT04411810
- Testing
- Nevisense 3.0, Dermlite Cam, Skin biopsy
- Where
- United States
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Breast Cancer
Monitoring Response to Neoadjuvant Chemotherapy in Breast Cancer Using Ultrafast DCE-MRI
The study will assess whether changes in kinetic parameters of tumor and peritumoral vasculature using ultrafast dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) during neoadjuvant chemotherapy (NAC) are predictive…
- Trial name
- NCT05744518
- Testing
- Response monitoring
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Fudan University
Breast Cancer, Social Determinants of Health (SDOH)
Early Point-of-Service Social and Behavioral Determinants of Health (SBDOH) Screening and Enhanced Navigation on Care Delivery for Patients With Breast Cancer
The overarching goal of this project is to optimize the collection of social and behavioral determinants of health (SBDOH) for patients with a pathological diagnosis of breast cancer at Penn Medicine.
- Trial name
- Breast_SBDOH (NCT06019988)
- Testing
- Early Point-of-Service Social and Behavioral Determinants of Health (SBDOH) Screening
- Where
- United States
- Volunteers
- 2,500 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Breast Cancer
Quantitative Dynamic Contrast Enhanced Breast MRI
The purpose of this study is to see if dynamic contrast enhanced (DCE) MRI imaging makes it possible to distinguish benign conditions of the breast from malignant tumors and provide better information than can be obtained with…
- Trial name
- NCT00582764
- Testing
- perform dynamic contrast enhanced (DCE) MRI
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Hirsutism, Hypertrichosis
Enhanced Safety Laser Hair Removal System
The purpose of this study is to determine whether a new laser system provides better safety and efficacy in hair removal than existing lasers.
- Trial name
- NCT00441948
- Testing
- Peterio
- Where
- Israel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Scilex Ltd.
Breast Neoplasm Female, Quality of Life
Wearable Enhanced Fitness Tracking for Metastatic Breast Cancer Patients Using Endocrine Treatment and Palbociclib
Combining a fitness tracker technology with real-time patient-reported outcome monitoring associated with interventions through a health care app is a novel strategy to evaluate metastatic breast cancer patients using Palbociclib…
- Trial name
- WEFITTER (NCT05277935)
- Testing
- Use of the WeCancer app combined with the smartwatch.
- Where
- 4 sites in Brazil
- Volunteers
- 68 people
- Sponsor
- Beneficência Portuguesa de São Paulo
DCIS, Breast Carcinoma in Situ
The Added Value of Contrast Enhanced Mammography to Standard Mammography in Assessing the Extent of DCIS
The study hypothesis is that the rate of inadequate surgical margins after conservative breast surgery for DICS and the rate of reoperation (re-excision or/and mastectomy) is lower in the group of patients who underwent standard…
- Conditions
- DCIS, Breast Carcinoma in Situ, Calcification
- Trial name
- CEMinDCIS (NCT06217458)
- Testing
- Contrast Enhanced Mammography
- Where
- Croatia
- Volunteers
- 100 people
- Sponsor
- Clinical Hospital Center Rijeka
Anatomic Stage IV Breast Cancer AJCC v8, Hormone Receptor Positive Breast Adenocarcinoma
Immunotherapy (NHS-IL12 & Bintrafusp Alfa) and Radiation Therapy for the Treatment of Hormone Receptor Positive, HER2 Negative Metastatic Breast Cancer, the REINA Trial
This phase I trial is to find out the best dose, possible benefits and/or side effects of NHS-IL12 given together with bintrafusp alfa and radiation therapy in treating patients with hormone receptor positive, HER2 negative…
- Conditions
- Anatomic Stage IV Breast Cancer AJCC v8, Hormone Receptor Positive Breast Adenocarcinoma, Metastatic Breast Carcinoma, Metastatic HER2 Negative Breast Adenocarcinoma
- Trial name
- NCT04756505
- Testing
- Bintrafusp Alfa, Immunocytokine NHS-IL12, Radiation Therapy
- Sponsor
- M.D. Anderson Cancer Center
Rheumatoid Arthritis
Ultrasound Efficacy in Moderate Rheumatoid Arthritis
The objectives of this research study are to determine the frequency of low synovitis scores by ultrasound in patients with Rheumatoid Arthritis in moderate or high disease activity and to compare physician treatment…
- Trial name
- NCT04662359
- Testing
- Ultrasound Assessment
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Pennsylvania
Vitiligo
Enhanced Transcutaneous Delivery of Betamethasone for the Treatment of Vitiligo
Vitiligo is the commonest acquired depigmenting disorder characterized by loss of melanocytes from the basal layer of skin causing white patches which leads to great psychological distress in many patients.
- Trial name
- NCT05233735
- Testing
- Enhanced Transcutaneous Delivery of Topical Betamethasone after the treatment with Tixel, Topical treatment
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Breast Cancer
Assessment of Cardiotoxicity After Chemotherapy for Breast Cancer by Cardio-vascular Magnetic Resonance (MR)
Consecutive patients with a first diagnosis of breast cancer will be identified at the Tom Baker Cancer Centre (TBCC) and included into the study, if they are going to receive chemotherapy with anthracyclines and / or Trastuzumab…
- Trial name
- Cardiotox (NCT00679874)
- Testing
- Cardio-vascular MRI
- Where
- Canada
- Volunteers
- 66 people
- Sponsor
- University of Calgary
Breast Cancer
Magnetic Resonance Imaging in Women Receiving Chemotherapy for Stage III Breast Cancer
RATIONALE: Diagnostic procedures such as magnetic resonance imaging (MRI) may help determine the effectiveness of chemotherapy in killing breast cancer and allow doctors to plan more effective treatment.
- Trial name
- ACRIN 6657 (NCT00043017)
- Testing
- MRI/MRS, gadopentetate dimeglumine
- Where
- 11 sites in United States
- Volunteers
- 356 people
- Sponsor
- American College of Radiology Imaging Network