Clinical trials: Skin Enhancement
Healthy Adults, Skin Enhancement
A Study to Evaluate The Impact on Skin Quality Attributes by Juvederm® Volite Injection on Healthy Volunteers
To evaluate the impact on skin quality attributes, including physical measurements and gene and protein expression (histological and genomic analysis), following administration of Juvéderm® VOLITE in the volar forearms of healthy…
- Trial name
- NCT04206293
- Testing
- Juvederm® VOLITE
- Where
- Poland
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Allergan
Breast Cancer, Gynecologic Cancer
Mobile App Postoperative Home Monitoring After Enhanced Recovery Oncologic Surgery
This study will assess whether the implementation of a combination of ERAS (Enhanced Recovery After Surgery) protocols and postoperative followup via a smartphone app can offer 1) improved patient satisfaction, 2) virtual patient…
- Trial name
- ERAS-OncoRe (NCT03456167)
- Testing
- RecoverWell mobile app for follow-up care
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Alberta Health Services, Calgary
Diabetes Mellitus, Type 2, Diabetic Foot
Prostacyclin (PGI2) Pathway to Enhance Wound Healing in Diabetic Foot Ulcers
Prospective, monocentric, pathophysiological study, comparing 3 parallel groups: healthy controls; patients with diabetes and without DFU; patients with diabetes and with DFU.
- Trial name
- PGI2HEAL (NCT05099367)
- Testing
- Microdialysis, current induced vasodilation, Skin biopsy, peri-ulcerated skin biopsy
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Carcinoma, Basal Cell, Carcinoma, Squamous Cell
Optical Imaging for Preoperative Delineation of Nonmelanoma Skin Cancers
The purpose of the study is to evaluate the ability and efficacy of using a polarization-enhanced reflectance and fluorescence imaging device, PERFIS, (see the Device Brochure) for demarcation of nonmelanoma skin cancer margins…
- Trial name
- PERFIS (NCT02666833)
- Testing
- Polarization Enhanced Reflectance and Fluorescence System
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Skin Cancer
SpotCheck: Comparison of Enhanced Telemedicine Versus In-person Evaluation for the Diagnosis of Skin Cancer
The overall goal of this research is to develop a platform that can increase patient access to expert skin cancer diagnostic services via telemedicine.
- Trial name
- NCT04411810
- Testing
- Nevisense 3.0, Dermlite Cam, Skin biopsy
- Where
- United States
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Breast Cancer
Study of Dual-energy (DE) Contrast-enhanced (CE) Digital Mammography
This is a feasibility study to evaluate dual-energy (DE) contrast-enhanced (CE) digital mammography to detect breast cancer in patients with increased breast density (BI-RADS category c or d).
- Trial name
- NCT02995980
- Testing
- Dual-Energy Contrast-Enhanced (DECE) mammography, digital mammography
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Breast Cancer
Comparison of Breast Cancer Screening With CESM to DBT in Women With Dense Breasts
The over-arching goal of the Contrast-Enhanced Spectral Mammography Imaging Screening Trial (CMIST) is to determine if dual-energy contrast-enhanced spectral mammography (CESM) can detect more cancers with fewer false positives…
- Trial name
- CMIST (NCT05625659)
- Testing
- Dual-Energy Contrast-Enhanced Spectral Mammography (CESM)
- Where
- 13 sites in United States, Canada
- Volunteers
- 2,032 people, healthy volunteers welcome
- Sponsor
- American College of Radiology
Androgenic Alopecia
Autologous Stromal Vascular Fraction in Treatment of Male Androgenic Alopecia
Evaluation of Safety and efficacy of autologous stromal vascular fraction derived from denovo versus platelet rich plasma enhanced donner site in treatment of male androgenic alopecia
- Trial name
- NCT06326359
- Testing
- autologous stromal vascular fraction
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sohag University
Breast Neoplasm
GenetiKiT: Evaluation of an Educational Intervention on the Delivery of Genetics Services by Family Physicians
There is an urgent need for a knowledge translation strategy to facilitate the integration of genetics into family medicine, to improve the low knowledge base of most Canadian family physicians, ensure that the needs are met of…
- Trial name
- NCT00295529
- Testing
- Multifaceted educational intervention
- Where
- Canada
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Healthy
Pretreatments of the Skin Prior to PDT
The study investigates the potential of a range of different physical pretreatments to enhance methyl aminolevulinate (MAL)-induced protoporphyrin IX (PpIX) in the skin prior to photodynamic therapy (PDT).
- Trial name
- NCT02372370
- Testing
- Microneedle pretreatment + MAL-PDT, Sandpaper pretreatment + MAL-PDT, Curettage pretreatment + MAL-PDT
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Breast Cancer
ThermoBreast - Non-contact Breast Cancer Imaging Using AI-enhanced Thermography.
Breast cancer is one of the most worrisome health concerns facing women. Early detection and active patient monitoring are crucial to survival. The chances of a cure are high when detected and treated in the early stages.
- Trial name
- ThermoBreast (NCT06266026)
- Testing
- ThermoBreast - AI-based evaluation of dynamic breast thermography imaging
- Where
- Germany
- Volunteers
- 28,000 people, healthy volunteers welcome
- Sponsor
- ThermoMind Ltd.
Pressure Injuries, Pressure Ulcer Prevention
Gamified Learning for Pressure Injury Prevention
The goal of this Randomized Controlled Trial is to define the effect of gamified teaching methods for pressure injury prevention in intensive care nurses.
- Trial name
- NCT07028892
- Testing
- A gamified mobile learning, Booklet training
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mehmet Akif Ersoy University
Adipose Tissue
Evaluation of CoolSculpt Combining Venus Legacy Technology for Enhanced Results in Fat Reduction & Laxity of the Flanks
The purpose of this study is to evaluate the effect on the subject outcome using the combination of the Zeltiq Cryolipolysis device and the Venus Concept multipolar radiofrequency device with varipulse technology for the enhanced…
- Trial name
- NCT02569112
- Testing
- multipolar RF, varipulse, cryolipolysis
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Venus Concept
Acquired Absence of Lower Limb, Scar Condition and Fibrosis of the Skin
LASER Pilot Project
Veterans who use prosthetic limbs commonly suffer from skin problems such as scars that create discomfort and pain to the point that wearing the prosthesis is no longer tolerable.
- Trial name
- LASER (NCT05966636)
- Testing
- Fractional CO2 Laser Ablative Resurfacing
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Early Primary Breast Cancer
KVUS at Neoadjuvant CTx of Breast Cancer
Effect of the contrast-enhanced diagnostic ultrasound during neoadjuvant chemotherapy of breast cancer on the achieved tumor size reduction and tolerability of chemotherapy
- Trial name
- NCT03385200
- Testing
- SonoVue
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- RWTH Aachen University
Breast Cancer
Evaluation of Patients With Breast Cancer Using DCE-MRI, MRS, and Proteomics
RATIONALE: Diagnostic procedures, such as dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI), magnetic resonance spectroscopy (MRS), and tissue proteomics, may help doctors find and diagnose breast cancer and plan the…
- Trial name
- NCT00656604
- Testing
- proteomic profiling, lumpectomy or mastectomy, dynamic contrast-enhanced magnetic resonance imaging
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Vanderbilt-Ingram Cancer Center
Burn Wound, 2nd Degree Burn of the Skin
Ultrasound Treatment on Wound Healing Time
This is a randomized, sham-controlled pilot study that will assess the safety and feasibility of splenic focused pulsed ultrasound treatment on burn wound healing time in 24 subjects (12 active ultrasound and 12 sham controls).
- Trial name
- GE-MTEC (NCT05796492)
- Testing
- Pulsed splenic ultrasound, Ultrasound probe (no energy applied)
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- General Electric Research
Breast Cancer Early Stage Breast Cancer (Stage 1-3)
Reflects the Intervention (AI Chatbot)
The goal of this clinical trial is to investigate the impact of an AI-powered chatbot intervention on improving knowledge, attitudes, and empowerment in breast cancer patients.
- Trial name
- BC-CHAT (NCT06943911)
- Testing
- AI Chatbot for Breast Cancer Patient Education and Empowerment
- Where
- Egypt
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Mostafa Shaban
Healthy, Dermoscopy
Topical Tartrazine for Improved Skin Structure Visualization in Dermatology
The goal of this clinical trial is to learn if the topical application of tartrazine, an FDA-approved food dye, can help improve the transparency of the skin in healthy volunteers.
- Conditions
- Healthy, Dermoscopy, Optical Imaging
- Trial name
- NCT06800183
- Testing
- Four-Chamber Tartrazine Patch across 3 Body Sites
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Hirsutism, Hypertrichosis
Enhanced Safety Laser Hair Removal System
The purpose of this study is to determine whether a new laser system provides better safety and efficacy in hair removal than existing lasers.
- Trial name
- NCT00441948
- Testing
- Peterio
- Where
- Israel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Scilex Ltd.