Clinical trials: Skin Flaps
Sarcoma, Breast Cancer
Augmented Reality (AR): The Future of "Patient Information Leaflets
This project aims to assess a new type of Augmented Reality Patient Information leaflet, in order to demonstrate that it is a beneficial information resource to patients when facing the diagnosis of sarcoma, breast cancer or to…
- Conditions
- Sarcoma, Breast Cancer, Cleft Lip and Palate, Surgical Flap
- Trial name
- NCT04619030
- Testing
- Augmented Reality, Traditional leaflet
- Where
- 3 sites in United Kingdom
- Volunteers
- 20 people
- Sponsor
- NHS Greater Glasgow and Clyde
Breast Cancer, Breast Reconstruction
The Outcomes of Fat Grafting Combined With Latissimus Dorsi Muscle Flap for Delayed Breast Reconstruction After Mastectomy
The outcomes of fat grafting combined with latissimus dorsi muscle flap for delayed breast reconstruction after mastectomy
- Trial name
- NCT07331753
- Testing
- Fat grafting combined with latissimus dorsi muscle flap
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Sohag University
Carcinomatous Resections, Violent Trauma
Evaluation of the PICO® Negative Pressure Dressing System on the Fibula Free Flap Donor Site's Skin Graft.
A fibula free flap can be used for the reconstruction of a mandible or a maxillar when the lack of bonne exceeds 3cm. This flap is made of the fibula bone, some muscle around, the fibular vascular pedicle and a skin paddle to…
- Trial name
- PICOFLAP (NCT04628416)
- Testing
- PICO dressing, Conventional dressing
- Where
- France
- Volunteers
- 112 people
- Sponsor
- University Hospital, Montpellier
Breast Cancer, Breast Reconstruction
Sensory Restoration After DIEP Flap Neurotization
Common goals of breast reconstruction include obtaining satisfactory breast symmetry, softness, and appropriate size and shape. Advances in surgical techniques have prompted a new goal: achieving breast sensation after…
- Conditions
- Breast Cancer, Breast Reconstruction, Sensory Restoration
- Trial name
- NCT04533373
- Testing
- DIEP Flap Neurotization
- Where
- United States
- Volunteers
- 156 people
- Sponsor
- Johns Hopkins University
Breast Cancer
Application of VascuLens 2.0, A Mixed Reality System for Surgical Guidance During DIEP Flap Harvest
This study incorporates the use of the VascuLens system, which relies on a mixed reality headset and software system, during the pre-operative stage of DIEP flap surgery.
- Trial name
- VascuLens RCT (NCT07080463)
- Testing
- vasculens and cta
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
Breast Cancer
Opioid Free Versus Opioid Based Anaesthesia for Free Flap Reconstruction Surgery of the Breast: A Phase III Multicentric Randomized Controlled Study.
This study will compare morphine consumption during the first 48 hours postoperatively between the OFA group and the CA control group.
- Trial name
- OFOBA (NCT05439005)
- Testing
- Dexmedetomidine
- Where
- 3 sites in France
- Volunteers
- 158 people
- Sponsor
- Institut Curie
Breast Cancer, Hereditary Breast/Ovarian Cancer (brca1, brca2)
Outcomes After Perforator Flap Reconstruction for Breast Reconstruction and/or Lymphedema Treatment
The goal of this prospective, observational study is to investigate the clinical, psychosocial, and patient satisfaction outcomes of patients who undergo perforator flap reconstruction for breast reconstruction and/or…
- Conditions
- Breast Cancer, Hereditary Breast/Ovarian Cancer (brca1, brca2), Acquired Lymphedema, Congenital Lymphedema
- Trial name
- NCT01273909
- Testing
- Perforator Flap Breast Reconstruction, Vascularized Lymph Node Transfer
- Where
- 3 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- The National Institute of Lymphology
Oral Cancer, Oral Cavity Cancer
Radial Forearm Donor Site Closure
The radial forearm free flap (RFFF) is widely used in head and neck reconstruction. Its thinness, pliability, pedicle length, and vessel size are particularly suited for oropharyngeal and oral cavity reconstruction.
- Conditions
- Oral Cancer, Oral Cavity Cancer, Donor Site Complication
- Trial name
- NCT05740033
- Testing
- Split-Thickness Skin Graft for Radial Forearm Donor Site Closure, Hatchet Flap for Radial Forearm Donor Site Closure
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- University of British Columbia
Intraabdominal Hypertension, Breast Neoplasms
DIEP Flap Surgery and Intraabdominal Pressure
Aim: The primary aim of this study is to test if closure of the abdominal donor site increases the Intraabdominal Pressure (IAP) in women undergoing secondary Deep Inferior epigastric perforator (DIEP) flap breast reconstruction.
- Trial name
- NCT05764577
- Testing
- DIEP flap surgery
- Where
- Denmark
- Volunteers
- 13 people
- Sponsor
- Aalborg University Hospital
Scar Conditions and Fibrosis of Skin
Dermabrasion for Free Flap Aesthetic Enhancement
The purpose of this study is to evaluate the aesthetic benefit and safety of serial dermabrasion for free flap skin paddles and donor site scars in head and neck reconstruction.
- Trial name
- NCT07233200
- Testing
- Dermabrasion
- Volunteers
- 40 people
- Sponsor
- Milton S. Hershey Medical Center
Breast Cancer
Patient-Reported Outcome and Safety Between Preoperative and Postmastectomy Radiotherapy in DIEP Flap Reconstruction
This study is the first prospective randomized study assessing the patient-reported outcomes and safety outcomes between preoperative and postmastectomy radiotherapy in locally advanced breast cancer patients with immediate…
- Trial name
- CAPPELLA (NCT05512286)
- Testing
- Preoperative radiotherapy, Postmastectomy radiotherapy
- Where
- 6 sites in China
- Volunteers
- 80 people
- Sponsor
- Fudan University
Surgical Flaps, Skin Pigmentation
Evaluation of the Postoperative Effect of Expanded Pedicled Deltopectoral Flap to Repair the Facial-Cervical Scars
This study evaluates the effect of Expanded Pedicled Deltopectoral Flap on facial-cervical scars repair, including flap sensation, L*a*b* value,flap's elasticity,melanin content, hemoglobin content, and evaluation of scar and…
- Conditions
- Surgical Flaps, Skin Pigmentation, Sensory Defect
- Trial name
- NCT03735641
- Testing
- Expanded Pedicled Deltopectoral Flap
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Xijing Hospital
Skin Cancer, Basal Cell, Skin Cancer
A Comparison of Skin Grafts Versus Local Flaps for Facial Skin Cancer From the Patient Perspective: A Feasibility Study
A prospective single-centered feasibility study will be conducted. The purpose of the feasibility study is to define the variables to be included in a subsequent pilot study, assess the feasibility of conducting a prospective…
- Conditions
- Skin Cancer, Basal Cell, Skin Cancer, Skin Cancer, Non-Melanoma, Skin Cancers - Squamous Cell Carcinoma
- Trial name
- NCT04805905
- Testing
- FACE-Q patient reported outcome
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- McMaster University
Acute Wound, Traumatic Wound
Confirm the Safety and Performance of Avance Solo NPWT System
The primary objective of this post market clinical follow-up (PMCF) investigation is to confirm safety and performance of Avance® Solo NPWT System in low to moderate exuding acute (traumatic wounds and flaps and grafts), as well…
- Conditions
- Acute Wound, Traumatic Wound, Skin Graft, Skin Flap
- Trial name
- ASOLO-SW (NCT04754048)
- Testing
- Avance Solo NPWT System
- Where
- 10 sites in Belgium, France and 2 more
- Volunteers
- 105 people
- Sponsor
- Molnlycke Health Care AB
Breast Cancer
Outcomes of a Deep Inferior Epigastric Perforator Flap Program
The purpose of this study is to analyze an institution's experience with starting a subspecialized DIEP flap program.
- Trial name
- NCT00543907
- Where
- United States
- Volunteers
- 977 people
- Sponsor
- Beth Israel Deaconess Medical Center
DIEP Flap, Breast Reconstruction
ORASIS in Breast Reconstruction
The purpose of this study is to assess the use of ORASIS during microsurgical anastomosis formation in Deep Inferior Epigastric Perforator (DIEP) flap breast reconstruction and its potential effects on surgical precision, surgeon…
- Conditions
- DIEP Flap, Breast Reconstruction, Breast Cancer
- Trial name
- NCT07670754
- Testing
- Use of ORASIS Device
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Duke University
Microvascular Free Flap Transfer, Fibula Flap
Artificial Intelligence-Enabled Skin Perforator Segmentation
Computer-assisted surgery has revolutionized reconstruction with more efficient, accurate, and predictable surgery, as reported in our previous studies.
- Trial name
- NCT06634472
- Testing
- artificial intelligence
- Where
- Hong Kong
- Volunteers
- 49 people
- Sponsor
- The University of Hong Kong
Wound; Head, Multiple, Wound; Head, Scalp
Short Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
This study will evaluate the use of free autologous dermal fat grafting (also called free dermal fat autografting) to treat complex craniofacial wounds that have failed standard treatment and to understand how well these grafts…
- Conditions
- Wound; Head, Multiple, Wound; Head, Scalp, Wound; Head, Wound Infection
- Trial name
- FTFDT3 (NCT03872544)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dufresne, Craig, MD, PC
Pressure Injury
Determinants of the Success of Flap Reconstruction: Outcome Analysis of 484 Surgeries for Pressure Injury
Background: Pressure injury (PI) mainly occurs in bedridden older adults or those with physical limitations. PI treatment is typically long-term, requiring coordination between health-care workers and the patient's caregiver.
- Trial name
- NCT05441293
- Testing
- flap reconstruction
- Volunteers
- 484 people
- Sponsor
- Taipei Medical University WanFang Hospital
Breast Cancer
Nerve Coaptation in LTP Flap Breast Reconstruction
The sensory recovery of the breast remains an undervalued aspect of breast reconstruction and surgical reinnervation is not regarded as a priority by most reconstructive surgeons.
- Trial name
- NCT03959943
- Testing
- Sensory nerve coaptation
- Where
- Netherlands
- Volunteers
- 46 people
- Sponsor
- Maastricht University Medical Center