Clinical trials: Skin Graft
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Biphenotypic Leukemia
Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors in Preventing GVHD
This phase II trial is for patients with acute lymphocytic leukemia, acute myeloid leukemia, myelodysplastic syndrome or chronic myeloid leukemia who have been referred for a peripheral blood stem cell transplantation to treat…
- Conditions
- Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Biphenotypic Leukemia, Acute Leukemia of Ambiguous Lineage, Acute Undifferentiated Leukemia
- Trial name
- NCT02220985
- Testing
- Allogeneic Hematopoietic Stem Cell Transplantation, Cyclophosphamide, Fludarabine Phosphate
- Where
- 2 sites in United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Breast Cancer
Prospective Radiologic Evaluation of Changes Following Fat Grafting
Breast implants are currently used for cosmetic breast augmentation and in breast reconstruction following mastectomy for breast cancer.
- Trial name
- NCT01343030
- Where
- 2 sites in United States, France
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Skin Wound, Scar, Hypertrophic
Umbilical Cord Stem Cells for Skin Grafts in Donor Site Wounds
The goal of this clinical trial is to evaluate the safety and effectiveness of human umbilical cord mesenchymal stem cell (hUCMSC) therapy in patients undergoing medium-thickness skin grafts for donor site wounds.
- Trial name
- NCT05984628
- Testing
- human umbilical cord mesenchymal stem cells, blank solvent
- Where
- China
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University Union Hospital
Donor Site Complication, Skin Graft Scar
A Single Center Trial of Donor Site Wound Dressings After Split Thickness Skin Grafting.
The goal of this clinical trial] is to compare different types of dressings used and there outcomes on STSG donor site wound. The main question[s] it aims to answer are: the effectiveness of different donor site dressings and…
- Trial name
- NCT06044519
- Testing
- different types of dressings
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Nonsuicidal Self Injury, Stigmatization
Scar Resection and Reconstruction With Integra and Split Skin Grafts in Patients With Non-Suicidal Self-Inflicted Scars
Non-suicidal self-inflicted (NSSI) scars can act as a physical reminder of previous self-inflicted self-harm, thereby not only worsening the symptoms of depression and self-doubt but also leading to recurrent self-infliction and…
- Conditions
- Nonsuicidal Self Injury, Stigmatization, Cicatrix, Skin Transplantations
- Trial name
- NCT04420442
- Testing
- Scar Transformation Group
- Where
- Germany
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Berufsgenossenschaftliche Unfallklinik Ludwigshafen
Non-healing Wound
Effect of Lidocaine and Adrenaline Soaked Gauze Versus Normal Saline Soaked at Skin Graft Donor Site of Thigh
Investigator is studying the effects of Lidocaine and Adrenaline Soaked Gauze vs Normal Saline Soaked Gauze at Skin Graft Donor Site of Thigh.
- Trial name
- NCT04344483
- Testing
- 2% Lidocaine and 1:100,000 Adrenaline, Normal saline
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Wound of Skin, Wound Heal
Efficacy and Safety of 0.25% Timolol Gel in Enhancing Full Thickness Skin Grafts Healing and Cosmetic Outcomes
The use of topical beta-blockers, such as 0.25% timolol, in promoting wound healing is currently emerging in the academic literature.
- Conditions
- Wound of Skin, Wound Heal, Surgical Wound, Full Thickness Skin Graft Healing
- Trial name
- FTSG (NCT03579160)
- Testing
- 0.25% timolol gel with full-thickness skin grafts, Vaseline dressing
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Peyronie's Disease
Investigation of Surgery, Collagenase, and Restorex for the Improvement of Peyronie's
The purpose of this study is to compare key clinical outcomes of collagenase clostridium histolyticum injections versus surgery for the management of Peyronie's Disease.
- Trial name
- iSCRIP (NCT04786106)
- Testing
- Collagenase Clostridium Histolyticum 0.9 MG [Xiaflex] (CCH), Penile Plication Surgery, Incision and Grafting (I&G) Surgery
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Charitable Union for the Research and Education of Peyronie's Disease
Skin Transplantation
Post-market Clinical Follow-up Study for a CE Marked Wound Care Product (FibDex®)
FibDex® 2-2022 is a sponsored, post-marketing clinical follow-up (PMCF) study to monitor the clinical performance and safety of the CE marked product nanofibrillar cellulose (NFC) wound dressing, FibDex®, when used according to…
- Trial name
- NCT05666999
- Testing
- FibDex®, Suprathel, Aquacel Foam
- Where
- Finland
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- UPM-Kymmene Corporation
Burns, Skin Graft Complications
Suprathel Versus Xeroform for the Management of Skin Graft Donor Sites
The investigators aim to study whether Suprathel, a synthetic temporary skin substitute developed by PolyMedics Innovations GmBH aids in the management of patient pain and wound healing when compared to the current standard…
- Conditions
- Burns, Skin Graft Complications, Skin; Deformity
- Trial name
- Suprathel (NCT04014400)
- Testing
- Suprathel or Xeroform donor site application
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Breast Cancer
Decellularized, Whole Donor Nipple-Areola Complex Reconstruction Grafts
The goal of this study is to evaluate safety and healing time after nipple-areolar complex (NAC) reconstruction with the BioAesthetics' decellularized human nipple-areolar complex (dcl-hNAC) graft in patients who have had…
- Trial name
- NCT04534010
- Testing
- NACgraft
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Stanford University
Atopic Dermatitis, Contact Dermatitis
Exploratory Study of Natural Killer Cells in Human Skin
Natural Killer (NK) cells play a unique role during innate immune responses as they are able to recognize and eliminate, without specific sensitization, tumors, microbe-infected cells as well as allogeneic cells.In a first time…
- Conditions
- Atopic Dermatitis, Contact Dermatitis, Psoriasis, Lichen Planus
- Trial name
- NCT00824889
- Testing
- Biopsy and sample of blood
- Where
- France
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Head and Neck Cancer, Surgery--Complications
Tumescence in HNC Skin Graft Reconstruction
Our primary objective is to determine if the use of tumescence has a meaningful effect on STSG uptake at the recipient site. This is an important outcome because poor graft uptake results in the need for prolonged local wound…
- Conditions
- Head and Neck Cancer, Surgery--Complications, Graft Failure
- Trial name
- NCT04967391
- Testing
- Tumescence During STSG Harvest
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Wound of Skin, Non-melanoma Skin Cancer
Efficacy and Safety of a Nanofat-seeded Biological Scaffold in Healing Lower Limb Surgical Defects
Large full-thickness skin defects, such as those resulting from trauma, large and giant congenital nevi, disfiguring scars, or tumor resection remain major clinical problems to patients and physicians.
- Conditions
- Wound of Skin, Non-melanoma Skin Cancer, Skin Graft Complications, Wound of Lower Leg
- Trial name
- NCT03548610
- Testing
- Nanofat-seeded biological scaffold on surgical defect
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Rhinoplasty, Nasal Skin-soft Tissue Envelope Metabolism
The Impact of Rhinoplasty Approach and Used Autologous Cartilage Grafts on the Nasal Skin-soft Tissue Envelope Metabolism
This is a prospective observation cohort investigation. Patients, that is participants, undergoing primary functional rhinoplasty will be evaluated in terms of measuring capillary blood lactic acid concentration in the nasal…
- Conditions
- Rhinoplasty, Nasal Skin-soft Tissue Envelope Metabolism, Lactic Acid, Autologous Cartilage Grafting
- Trial name
- NCT06384469
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital Sestre Milosrdnice
Wound Healing
Comparison of Two Methods of Securing Skin Grafts Using Negative Pressure Wound Therapy: Vacuum Assisted Closure (VAC) and Gauze Suction (GSUC)
The purpose of this study is to compare how well two methods (VAC and G-SUC) of securing skin grafts using negative pressure wound therapy work.
- Trial name
- NCT00952120
- Testing
- GSUC, VAC
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Age, Cicatrix, Hypertrophic
Prospective Clinical Trials on Skin Wound Healing in Young and Aged Individuals
Regular wound healing follows a well-ordered sequence of overlapping phases: inflammation, proliferation, maturation and remodelling.
- Conditions
- Age, Cicatrix, Hypertrophic, Fibrosis, Diabetes Mellitus
- Trial name
- RESOLVE (NCT01040104)
- Testing
- Skin sample, Skin biopsy, Blood taking
- Where
- Austria
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Treatment of Donor Site Burns
Multi-Center, Prospective, Randomized, Comparison of AWBAT™-D vs. Xeroform™ or Glucan II™ for Treatment of Donor Sites in Burn Surgery
The purpose of this study is to compare the rate of healing and the non-adherence of three types of dressings. The study will also compare rate of infection, scarring and perception of pain associated with treatment.
- Trial name
- AWBAT-D (NCT00964470)
- Testing
- AWBAT™-D and XEROFORM™ OR GLUCAN II™ dressings
- Where
- 3 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aubrey Inc.
Hyperpigmentation
Fat Grafting an Ideal Filler For Contour Deformities With Hyperpigmentation On Face
Pigmentary changes are commonly associated with contour defects of facial region. These deformities cause cosmetic concerns. Traditionally used techniques indwelling limitations and therefore it invokes innovative techniques to…
- Trial name
- NCT06103461
- Testing
- Autologous fat grafting
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- King Edward Medical University
Burn Injury
Exercise in Burn Survivors: Cooling Modalities
This project will identify the efficacy of cooling modalities aimed to attenuate excessive elevations in skin and internal body temperatures during physical activity in well-healed burn survivors.
- Trial name
- NCT04512976
- Testing
- Control (no cooling modalities), Water Spray Only, Fan Only
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center