Clinical trials: Skin Grafting
Ischemic Heart Disease, Angina Pectoris
Investigation of Leukocyte Trafficking Into Skin Blisters During Cardiopulmonary Bypass
The purpose of this study was to see if the heart-lung machine involved in cardiac surgery increases the movement of activated white blood cells from the bloodstream into the patient's tissues and also to see if aprotinin usage…
- Trial name
- NCT00131040
- Testing
- Aprotinin
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Breast Cancer
Decellularized, Whole Donor Nipple-Areola Complex Reconstruction Grafts
The goal of this study is to evaluate safety and healing time after nipple-areolar complex (NAC) reconstruction with the BioAesthetics' decellularized human nipple-areolar complex (dcl-hNAC) graft in patients who have had…
- Trial name
- NCT04534010
- Testing
- NACgraft
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Stanford University
Wound Healing
Efficacy of Topical Heparin Spray on Donor Site Wound Healing Time Compared to Conventional Dressing Among Patients Undergoing Split Thickness Skin Grafting
Wound is defined by the breach in dermis of the skin. It can be caused by road traffic accidents, tumor excision, chronic illness like diabetes, bed sores in bedridden patients, burns, insects' bites etc.
- Trial name
- NCT04613336
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Healing of Donor Site, Pain Level
Study Evaluating AWBAT-D Versus the Standard of Care of Split-thickness Skin Graft Donor Sites
Use of AWBAT-D on split thickness skin graft sites will reduce healing time and pain level.
- Trial name
- NCT01252836
- Testing
- AWBAT-D
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Georgetown University
Peyronie's Disease (PD)
Comparative Outcomes of Subtunical Microdissection and Grafting Versus Classical Plaque Incision and Grafting in Complex Peyronie's Disease
The goal of this clinical study is to compare two surgical techniques used for the treatment of complex Peyronie's disease. Peyronie's disease can cause penile curvature, deformity, and difficulties during sexual intercourse due…
- Trial name
- Peyronie (NCT07470528)
- Testing
- Subtunical microdissection and grafting, Classic plaque Incision and Grafting
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Namik Kemal University
Wounds
OxyGenesys Dissolved Oxygen Dressing; Abdominoplasty at Northwestern University
Twelve acute wounds (6 on either side of the umbilicus) will be surgically created in the lower abdominal area. One side of the umbilicus will be randomized to Oxygenesys treatment arm and the other side will be receiving a…
- Trial name
- NCT02591537
- Testing
- OxyGenesys Dissolved Oxygen Dressing
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Halyard Health
Traumatic Skin Loss, 2nd and 3rd Degree Burn, Post Tumour Excision - Raw Areas Undergoes Split- Thickness Skin Grafts
Evaluation of the Use of Minced Skin Grafts for Promoting Donor Site Wound Healing After Split-Thickness Skin Grafting
Split-thickness skin grafting (STSG) is one of the most commonly performed procedures to achieve wound closure. Most studies are concerned on improving the appearance of scars and shortening the healing time of the recipient…
- Trial name
- NCT06488612
- Testing
- Minced skin grafts for donor site
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sohag University
Autoimmune Diseases, Sickle Cell Disease
Microvascular and Fibrosis Imaging Study
In this study, Laser Doppler Flowmetry (LDF), Laser Doppler Imaging (LDI), Orthogonal Polarization Spectral Imaging (OPSI), Nail fold video capillaroscopy (NVC) and Optical Coherence Tomography (OCT) will be used to assess…
- Conditions
- Autoimmune Diseases, Sickle Cell Disease, Chronic Graft Versus Host Disease
- Trial name
- NCT01758250
- Testing
- Acoustic Radiation Force Impulse (ARFI), Laser Doppler Flowmetry (LDF), Laser Doppler Perfusion Imaging (LDI)
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Duke University
GVHD
Allogeneic Skin Grafting
The primary study objective is to evaluate local response to split-thickness skin grafts from a matched bone marrow donor to chronic GVHD-affected skin in a hematopoietic stem cell transplant patient.
- Trial name
- NCT04015947
- Testing
- CelluTome® Epidermal Harvesting System
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Minnesota
Skin Graft Detachment
Method of Securing Skin Graft: A Comparison of Vacuum Assisted Closure Device Versus Bolster Dressing
The goal of this randomized controlled trial is to compare the outcomes of vacuum assisted closure device versus conventional bolster dressing in securing split thickness skin graft in traumatic wounds; with emphasis on…
- Trial name
- NCT05831020
- Testing
- VAC and bolster dressing
- Where
- Pakistan
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Wound Healing
Comparison of Two Methods of Securing Skin Grafts Using Negative Pressure Wound Therapy: Vacuum Assisted Closure (VAC) and Gauze Suction (GSUC)
The purpose of this study is to compare how well two methods (VAC and G-SUC) of securing skin grafts using negative pressure wound therapy work.
- Trial name
- NCT00952120
- Testing
- GSUC, VAC
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Punch Biopsy Wounds, Healing Times
Healing of Punch Graft Wounds. Comparative Study Between MariGen and Oasis: a Non-inferiority Study
The objective is to determine, if healing of punch biopsy wounds treated with the fish skin derived MariGen Wound dressing is non-inferior to healing with wounds treated with pig intestines derived Oasis Sheet wound dressing.
- Trial name
- NCT01917591
- Testing
- Punch biopsies treated with MariGen Wound ECM dressing, Punch biopsies treated with Oasis ECM dressing
- Where
- Iceland
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Kerecis Ltd.
Skin Cancer
Prospective, RCT of Split Thickness Skin Grafts on Lower Leg After Compression Therapy With Compression Bandage vs. NPWT
The single center, prospective, randomized trial includes in total 60 patients. We want to compare two different treatment methods for compression therapy for split thickness skin graft in lower leg.
- Trial name
- NCT03452852
- Testing
- PICO, Coban 2 lite
- Where
- Norway
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Wounds and Injuries, Skin Graft Scar
Effectiveness and Tolerability of Fitostimoline Plus vs Connettivina Bio Plus in Skin Graft
Partial thickness skin grafts are widely used to cover large losses of substance secondary to trauma, burns, ulcers, neoplasms. The donor site (SD), in principle, heals by spontaneous re-epithelialization from the epithelial…
- Conditions
- Wounds and Injuries, Skin Graft Scar, Skin Graft Complications
- Trial name
- FP (NCT05447793)
- Testing
- Fitostimoline plus, Connettivina bio plus
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Federico II University
Age, Cicatrix, Hypertrophic
Prospective Clinical Trials on Skin Wound Healing in Young and Aged Individuals
Regular wound healing follows a well-ordered sequence of overlapping phases: inflammation, proliferation, maturation and remodelling.
- Conditions
- Age, Cicatrix, Hypertrophic, Fibrosis, Diabetes Mellitus
- Trial name
- RESOLVE (NCT01040104)
- Testing
- Skin sample, Skin biopsy, Blood taking
- Where
- Austria
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Skin Wound, Scar, Hypertrophic
Umbilical Cord Stem Cells for Skin Grafts in Donor Site Wounds
The goal of this clinical trial is to evaluate the safety and effectiveness of human umbilical cord mesenchymal stem cell (hUCMSC) therapy in patients undergoing medium-thickness skin grafts for donor site wounds.
- Trial name
- NCT05984628
- Testing
- human umbilical cord mesenchymal stem cells, blank solvent
- Where
- China
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University Union Hospital
Nonsuicidal Self Injury, Stigmatization
Scar Resection and Reconstruction With Integra and Split Skin Grafts in Patients With Non-Suicidal Self-Inflicted Scars
Non-suicidal self-inflicted (NSSI) scars can act as a physical reminder of previous self-inflicted self-harm, thereby not only worsening the symptoms of depression and self-doubt but also leading to recurrent self-infliction and…
- Conditions
- Nonsuicidal Self Injury, Stigmatization, Cicatrix, Skin Transplantations
- Trial name
- NCT04420442
- Testing
- Scar Transformation Group
- Where
- Germany
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Berufsgenossenschaftliche Unfallklinik Ludwigshafen
Healthy Volunteers
A Study to Evaluate Pharmacokinetics of DRL_AB in Healthy Male Participants
The purpose of this study is to assess the PK comparability and compare safety and tolerability of DRL_AB administered via an auto injector (AI) or prefilled syringe (PFS) in healthy male participants.
- Trial name
- NCT07744828
- Testing
- DRL_AB
- Where
- 3 sites in New Zealand
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Head and Neck Cancer
Free Skin Grafting to Reconstruct Donor Sites After Radial Forearm Flap Harvesting
Reconstruction of the donor site after radial forearm flap harvesting is a common procedure in maxillofacial plastic surgery. Unfortunately, free skin graft transplantation faces wound healing impairments such as necrosis…
- Trial name
- NCT05137639
- Testing
- Platelet-rich fibrin (PRF)
- Where
- Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Wuerzburg University Hospital
Androgenic Alopecia
Condensed Nanofat Grafting for Treatment of Androgenetic Alopecia
Nowadays, multiple treatment modalities have been applied clinically to treat androgenic alopecia, such as Follicular unit transplantation(FUT), finasteride, platelet-rich plasma injection(PRP), etc.
- Trial name
- NCT03506503
- Testing
- Nanofat grafting
- Where
- China
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Jinan University Guangzhou