Clinical trials: Skin Infection
Skin Infections, Bacterial
Retapamulin Microdialysis Feasibility Study
This feasibility study will allow for the determination of the in vivo recovery and time of dialysis to optimize a future thorough microdialysis study.
- Trial name
- NCT01812382
- Testing
- Retapamulin Microdialysis
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Onychomycosis of Toenail
An Internet Mediated Research Study to Assess the Quality of Life of Consumers With Self-reported Fungal Nail Infection (Onychomycosis) During Treatment With Scholl Fungal Nail.
To evaluate the effect on quality of life of consumers with self-reported onychomycosis during the first 4 weeks of treatment in relation to the appearance of the infected toenail.
- Trial name
- NCT04084782
- Testing
- Fungal Nail Treatment Kit
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
Wound Complication
Cesarean Skin Incision Trial
The purpose of this study is to determine if there is a difference between Pfannenstiel and midline vertical skin incision at time of cesarean section in preventing wound complications in the morbidly obese patient.
- Trial name
- C-SIT (NCT01897376)
- Testing
- Pfannenstiel incision, vertical skin incision
- Where
- 2 sites in United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Skin Diseases, Bacterial
Study of Intravenous (I.V.) Iclaprim Versus Linezolid in Complicated Skin and Skin Structure Infections [cSSSI] (ASSIST-2)
The study is now completed
- Trial name
- NCT00303550
- Testing
- Intravenous iclaprim, Intravenous linezolid
- Where
- 2 sites in United States
- Sponsor
- Arpida AG
Hidradenitis Suppurativa
Study to Assess the Safety and Efficacy of Infliximab to Treat Hidradenitis Suppurtativa
A study to assess the safety and efficacy of the IV drug infliximab for the treatment of hidradenitis suppurativa
- Trial name
- HS2006 (NCT00795574)
- Testing
- infliximab
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Florida Academic Dermatology Centers
Dermatitis, Atopic
Atopic Dermatitis Research Network (ADRN) Influenza Vaccine Study
Atopic dermatitis, also called eczema, is a disease in which the skin is dry and scaly with severe itching. People who have atopic dermatitis often have complications from skin infections; these can include eczema herpeticum…
- Trial name
- NCT01737710
- Testing
- Fluzone® Intradermal Vaccine, Fluzone® (Intramuscular) vaccine
- Where
- 5 sites in United States
- Volunteers
- 368 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Bacterial Infections, Acute Bacterial Skin and Skin Structure Infection
Development of a New Critical Pathway for Treatment of Acute Bacterial Skin and Skin Structure Infections (ABSSSI)
The purpose of this study is to assess the effect of a new critical pathway (use of guideline-based patient identification criteria and for those who meet these criteria, use of dalbavancin) compared to usual care for the…
- Trial name
- NCT03233438
- Testing
- Dalbavancin, Usual Care
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- Allergan
Hidradenitis Suppurativa
Study to Evaluate Tulisokibart for Hidradenitis Suppurativa (MK-7240-012)
This is a phase 2b randomized, double-blind, placebo-controlled study of the safety and efficacy of tulisokibart in participants with moderate to severe hidradenitis suppurativa.
- Trial name
- NCT06956235
- Testing
- Tulisokibart
- Where
- 68 sites in United States, Argentina and 13 more
- Volunteers
- 149 people
- Sponsor
- Merck Sharp & Dohme LLC
Wound Healing, Wound Infection
Efficacy Study of a Bioelectric Dressing to Treat Wounds Caused by Curettage and Electrodesiccation
The purpose of this study is to determine whether a bioelectric wound dressing, a silver-coated dressing, or a silver-foam dressing are effective in the treatment of wounds resulting from curettage and electrodesiccation of skin…
- Trial name
- NCT01004055
- Testing
- Procellera™ Antimicrobial Wound Dressing, ACTICOAT™ Antimicrobial Barrier Dressing, Mepilex® Ag Silver Foam Dressing
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Vomaris Innovations
Locally Advanced or Metastatic Melanoma
Phase I Endovenous Administration of Oncolytic Adenovirus ICOVIR-5 in Patients With Advanced or Metastatic Melanoma
The investigators will evaluate the safety of a single endovenous infusion of ICOVIR5 in adults with locally advanced and metastatic melanoma. ICOVIR5 consists in a conditionally replicative or oncolytic adenovirus.
- Trial name
- NCT01864759
- Testing
- ICOVIR-5
- Where
- Spain
- Volunteers
- 14 people
- Sponsor
- Institut Català d'Oncologia
Tinea Corporis, Tinea Cruris
Efficacy and Safety of Terbinafine and Itraconazole
There is a rise in the prevalence in recent years especially in tropical countries along with an increase in the number of treatment failures with chronic and recurrent dermatophytosis.
- Conditions
- Tinea Corporis, Tinea Cruris, Tinea Faciei, Dermatophytoses
- Trial name
- NCT05881980
- Testing
- Terbinafine Tablets, Itraconazole
- Volunteers
- 150 people
- Sponsor
- Dhaka Medical College
Periorbital Hyperpigmentation, Periorbital Edema
A 12 Week Study to Evaluate the Efficacy of an Eye Cream
This single center, open-label clinical study was conducted to assess the efficacy and tolerance of a topical eye cream when used over the course of 12 weeks by healthy women with moderate to severe under-eye dark circles…
- Conditions
- Periorbital Hyperpigmentation, Periorbital Edema, Fine Lines, Wrinkle
- Trial name
- NCT05807620
- Testing
- Gentle Cleansing Lotion, Facial Moisturizer, Sunscreen SPF 30
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Molluscum Contagiosum
Comparison of 5% Potassium Hydroxide With 10% Potassium Hydroxide Solution in Treatment of Molluscum Contagiosum
Molluscum is a virus-related skin infestation which is commonly seen among children. Molluscipox virus, the largest human virus, causes it.
- Trial name
- NCT05634460
- Testing
- potassium hydroxide
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Combined Military Hospital Abbottabad
Surgical Site Infection (SSI), Ileostomy Closure
Linear Versus Purse String Skin Closure at Loop Ileostomy Reversal.
This study is a randomized controlled trial designed to compare two commonly used skin closure techniques-linear closure and purse-string closure-after loop ileostomy reversal surgery.
- Conditions
- Surgical Site Infection (SSI), Ileostomy Closure, Surgical Technique Comparison
- Trial name
- NCT07573423
- Testing
- Linear Skin Closure, Purse-String Skin Closure
- Where
- Pakistan
- Volunteers
- 252 people
- Sponsor
- Hayat Abad Medical Complex, Peshawar
Onychomycosis
Single-blind Evaluation of Device to Nail Micro-drilling in Onychomycosis
Based on manufacturer testing, no major difference in drilling condition is expected in this study compared to the drilling conditions previously established.
- Trial name
- NCT00941317
- Testing
- Pathformer (micro-drilling device)
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Galderma R&D
Pediculosis
Efficacy, Safety and Tolerability of a Novel Malathion Formulation in Patients 2 Years and Older With Head Lice
In this study, Malathion Gel 0.5% will be compared to Nix (permethrin 1%) as a treatment for head lice in patients 2 years of age and older. Malathion Gel 0.5% is a new formulation of an established head lice treatment.
- Trial name
- NCT00963508
- Testing
- Malathion gel 0.5%, Permethrin 1% rinse (Nix Crème)
- Where
- 7 sites in United States
- Volunteers
- 403 people
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Herpes Simplex, Schizophrenia
Valacyclovir Augmentation for Cognitive and Functional Remediation in Schizophrenia
The effects of Valacyclovir (VAV) augmentation or placebo (PLA) as adjuncts to conventional antipsychotic drug treatment will be evaluated among patients with schizophrenia who have been exposed to herpes simplex virus type 1…
- Conditions
- Herpes Simplex, Schizophrenia, Schizoaffective Disorder
- Trial name
- NCT01794897
- Testing
- Experimental: Valacyclovir treatment
- Where
- India
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Cutaneous Leishmaniasis
Documentation of Patient Outcomes for SSG/Allopurinol Combination Treatment in Ethiopia
Outcomes of patients receiving SSG and Allopurinol combination have never been documented systematically in Ethiopia. Therefore, it is not known how effective this combination is.
- Trial name
- NCT04699383
- Testing
- Sodium Stibogluconate with allopurinol
- Where
- Ethiopia
- Volunteers
- 105 people
- Sponsor
- Institute of Tropical Medicine, Belgium
Common Warts
A Trial of a Botanical Drug Containing East Indian Sandalwood Oil (EISO) for Treatment of Common Warts
Nonclinical studies have shown sandalwood oil to have anti-inflammatory, anti-fungal, antiviral, and anti-bacterial activities. Previous clinical studies have shown East Indian Sandalwood oil to be promising as a treatment for…
- Trial name
- NCT01286441
- Testing
- 10% EISO, 20% EISO, 30% EISO
- Where
- 20 sites in United States
- Volunteers
- 183 people
- Sponsor
- ViroXis Corporation
Rheumatoid Arthritis, COVID
Anti-rheumatic Drug Use and Risk of COVID-19 Infection in Rheumatoid Arthritis Patients
Rheumatoid arthritis (RA) patients have an underlying immune deficiency and typically treated with immunosuppressive drugs, which may increase the risk of COVID-19 infection.
- Trial name
- NCT04434118
- Testing
- Traditional antirheumatic drugs
- Where
- Egypt
- Sponsor
- Sadat City University
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