Clinical trials: Skin Quality
Rheumatoid Arthritis (RA)
Oral Versus Intramuscular Steroid Use to Control Rheumatoid Arthritis Flares
People living with rheumatoid arthritis (RA) often experience flares-periods where their symptoms suddenly get worse. These flares can cause significant pain, make it harder to move and do daily activities, and lower overall…
- Trial name
- STORM-RA (NCT07245732)
- Testing
- Glucocorticoid (GC)
- Where
- 5 sites in Canada
- Volunteers
- 220 people
- Sponsor
- Sunnybrook Health Sciences Centre
Burns, Full Thickness Burn
A Single-stage Bilayered Skin Reconstruction With Glyaderm®
The study will explore the potential of utilizing Glyaderm® in a single-stage engrafting process, aiming for a more cost-effective approach.
- Conditions
- Burns, Full Thickness Burn, Necrotizing Fascitis
- Trial name
- NCT06249971
- Testing
- Dermal subsitute Glyaderm + skin graft, Skin graft alone
- Where
- Belgium
- Volunteers
- 82 people
- Sponsor
- University Hospital, Ghent
Rheumatoid Arthritis
Quality of Life Study With Adalimumab in Rheumatoid Arthritis
The purpose of the study is to evaluate the ability of adalimumab combined with methotrexate to improve the quality of life in patients with active RA.
- Trial name
- NCT00234936
- Testing
- Adalimumab, Methotrexate
- Volunteers
- 200 people
- Sponsor
- Abbott
Oral Lichen Planus
Dexamethasone to Treat Oral Lichen Planus
This study will evaluate the effectiveness of dexamethasone 0.01% solution in treating pain associated with oral lichen planus, a chronic disease that causes painful ulcers inside the mouth.
- Trial name
- NCT00111072
- Testing
- dexamethasone 0.01% solution
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Obstructive Sleep Apnea
The Treatment of Obstructive Sleep Apnea With Continuous Positive Airway Pressure on Appearance and Age
The investigators hypothesized that the treatment of obstructive sleep apnea (OSA) with continuous positive airway pressure (CPAP) will positively affect the appearance of the patient.
- Trial name
- NCT02117271
- Testing
- continuous positive airway pressure, Breathe Right ®
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Nucleo Interdisciplinar da Ciencia do Sono
Breast Cancer, Breast - Female
Dance Intervention in Breast Cancer Treatment
This study aims to evaluate the effects of a dance program on physical and psychological outcomes in women undergoing breast cancer treatment.
- Conditions
- Breast Cancer, Breast - Female, Breast Cancer Females
- Trial name
- NCT07553702
- Testing
- Dance Program Group
- Where
- Brazil
- Volunteers
- 28 people
- Sponsor
- Federal University of Maranhao
Chronic Spontaneous Urticaria, Angioedema
Impact of Omalizumab on Quality of Life Measures and Angioedema Occurrence in Patients With CSU Refractory to Therapy
This study will assess the impact of omalizumab on the quality of life improvement when added to the standard therapy in refractory patients suffering from chronic spontaneous urticaria and angioedema.
- Trial name
- X-ACT (NCT01723072)
- Testing
- Omalizumab
- Where
- 25 sites in Germany
- Volunteers
- 91 people
- Sponsor
- Novartis Pharmaceuticals
Breast Cancer
Orall Administered Probiotics to Improve the Quality of the Vaginal Flora of Women With Breast Cancer and Chemotherapy.
The aim of this study is the improvement of the vaginal flora by at least two grades of the Nugent scale after application of oral probiotics.
- Trial name
- NCT01723592
- Testing
- Probiotics
- Where
- Austria
- Volunteers
- 27 people
- Sponsor
- Medical University of Vienna
Breast Cancer
Patient-Assisted Compression - Impact on Image Quality and Workflow
This study is being conducted to compare the image quality of breast images obtained using standard (technologist-controlled [TC]) compression and patient-assisted (PA) compression and to evaluate the impact of PA compression on…
- Trial name
- NCT03196635
- Testing
- Patient-Assisted (PA) Breast Compression, Technologist-Controlled (TC) Breast Compression
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- GE Healthcare
Alopecia
Evaluation of Scalp Cooling During Chemotherapy on Quality of Life and the Potential Role of Single Nucleotide Variations on Chemotherapy-Induced Alopecia and Hair Regrowth in the Appalachian Highlands Region
This single-blind, randomized controlled trial is proposed to assess the effects of the PAXMAN Scalp Cooling System on the quality of life of breast cancer subjects receiving any treatment regimen consisting of a chemotherapy…
- Trial name
- NCT07422376
- Testing
- Paxman Scalp Cooling System
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Charles Mays
Onychomycosis of Toenail
An Internet Mediated Research Study to Assess the Quality of Life of Consumers With Self-reported Fungal Nail Infection (Onychomycosis) During Treatment With Scholl Fungal Nail.
To evaluate the effect on quality of life of consumers with self-reported onychomycosis during the first 4 weeks of treatment in relation to the appearance of the infected toenail.
- Trial name
- NCT04084782
- Testing
- Fungal Nail Treatment Kit
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
Breast Cancer Screening, Artificial Intelligence (AI)
Screening Mammography: Single Reading by One Radiologist With AI vs. Double Reading by Two Radiologists (AI-BCSQ)
A randomized prospective study comparing the evaluation of mammography images in a breast cancer screening programme by a single radiologist with AI support versus standard double reading by two radiologists without AI support.
- Conditions
- Breast Cancer Screening, Artificial Intelligence (AI), Breast Cancer Screening and Diagnosis
- Trial name
- AI-BCSQ (NCT07075679)
- Testing
- Group with AI iCAD version 3, Group without AI
- Where
- Czechia
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- University Hospital Olomouc
Cancer, Breast Cancer
An EORTC Study Updating the QLQ-BR23 to BR45
Female breast cancer is still the most frequent type of cancer in Europe with 21 per 100,000 women .The EORTC QLQ-BR23 was one of the first modules developed to be used in conjunction with the core questionnaire EORTC QLQ-C30 and…
- Trial name
- NCT04270123
- Testing
- EORTC QLQ-BR45 questionnaire
- Where
- United Kingdom
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Diabetes Mellitus, Diabetic Foot Ulcer
Contribution of Psychological Factors in the Healing of the Diabetic Foot Ulcer
Diabetic foot ulcers (DFU) are one of the most serious complications of diabetes and can lead to amputations in 85% of cases, resulting in physical, psychological, family, social and economic consequences.
- Trial name
- NCT04698720
- Testing
- Muscle Relaxation with Guided Imagery, Hypnosis with Guided Imagery, Neutral Guided Imagery
- Where
- 3 sites in Portugal
- Volunteers
- 69 people
- Sponsor
- University of Minho
Scleroderma, System; Sclerosis
Rehabilitation Program in Patients With Scleroderma
Scleroderma (or Systemic Sclerosis - SSc) is one of the most neglected diseases worldwide, according to the World Health Organization.
- Conditions
- Scleroderma, System; Sclerosis, Muscle Strain, Physical Disability
- Trial name
- NCT05041868
- Testing
- Treatment
- Where
- Brazil
- Volunteers
- 104 people
- Sponsor
- Centro Universitário Augusto Motta
Breast Cancer
Water-based Versus Land-based Exercise for Breast Cancer Survivors
Physical activity and exercise have demonstrated to be an integral part of the cancer-continuum care. Despite strong evidence suggesting that both endurance and strength training should be encourage in cancer patients, there is…
- Trial name
- NCT03730818
- Testing
- Water-based Exercise Group, Land-based Exercise Group
- Where
- Spain
- Volunteers
- 28 people
- Sponsor
- Universitat Pompeu Fabra
Breast Cancer, Cancer, Therapy-Related
Study of the Effects of Transcutaneous Vagus Nerve Stimulation on Cancer Patients
Patients diagnosed with breast cancer who received assisted radiotherapy were recruited and the transcutaneous auricular vagus nerve stimulation (taVNS) was applied.
- Conditions
- Breast Cancer, Cancer, Therapy-Related, Cancer-related Fatigue, Quality of Life
- Trial name
- NCT04563013
- Testing
- Transcutaneous vagus nerve stimulation
- Where
- China
- Volunteers
- 261 people
- Sponsor
- Xidian University
Breast Cancer
Psychosocial Adjustment of Patients and Their Partners Following Breast Cancer Diagnosis
The purpose of this study is to describe psychosocial adjustment in patients with breast cancer and their cohabiting partners/spouses throughout the cancer trajectory, to study mutual influences of the partner on the patient and…
- Trial name
- NCT01392066
- Testing
- questionnaire
- Where
- Denmark
- Volunteers
- 1,584 people
- Sponsor
- University of Southern Denmark
Oral Epithelial Dysplasia, Precancerous Conditions
Oral Epithelial Dysplasia Informational Needs Questionnaire
Background: Oral epithelial dysplasia (OED) is a condition with an increased risk of oral cancer. Due to the current changes in the factors associated with these diseases (because of human papillomavirus), it is expected that…
- Conditions
- Oral Epithelial Dysplasia, Precancerous Conditions, Precancerous Lesions, Oral Lichen Planus
- Trial name
- ODIN-Q (NCT04153266)
- Testing
- No intervention is planned for this study
- Where
- United Kingdom
- Volunteers
- 128 people
- Sponsor
- University College, London
Eczema, Dermatitis, Atopic
Integrative Body-Mind-Spirit Intervention for Families With Children Suffering From Eczema
This randomized controlled trial aims to examine the efficacy of two integrative body-mind-spirit interventions, compared to a health education active control, in promoting adaptive emotional regulation and quality of life of…
- Trial name
- NCT04617977
- Testing
- I-BMS for families with children suffering from eczema, Health education for parents whose children have eczema
- Where
- Hong Kong
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
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