Clinical trials: Skin Testing
Allergic Rhinitis, Asthma
Evaluation and Validation of Novel Diagnostic Tool for Allergists (AbioSCOPE)
In this study, investigators evaluated for the first time the diagnostic efficacy of abioSCOPE® versus Phadia Laboratory System as an aid in the diagnosis of allergic diseases.
- Trial name
- NCT03599908
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Recurrent Melanoma
Lymph Node Mapping Using Indocyanine Green Solution in Diagnosing Patients With Malignant Melanoma
This clinical trial compares and contrasts lymph node mapping using indocyanine green (IC-GREEN), isosulfan blue (ISB), and TSC and Lymphoscintigraphy with 99-technetium (99Tc) sulfur colloid (TSC).
- Trial name
- NCT01898403
- Testing
- Indocyanine green solution, Isosulfan blue (ISB), Lymphoscintigraphy with 99-technetium (99Tc) sulfur colloid (TSC)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Stanford University
Skin Sensitisation
HRIPT for Collagen Dressing
The objectives of this study are to determine by repetitive epidermal contact, the primary or cumulative irritation and the allergic contact sensitization potential of the ColActive Plus Collagen Matrix Dressing, under maximized…
- Trial name
- NCT06283173
- Testing
- ColActive Plus Collagen Matrix Dressing
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Covalon Technologies Inc.
Allergy to Platanus Acerifolia
Biological Standardization of Platanus Acerifolia Allergen Extract
The objective of this study is to determine the biologic activity of a Platanus acerifolia allergen extract in histamine equivalent prick (HEP) units, in order to be used as in-house reference preparation (IHRP).
- Trial name
- NCT01739322
- Testing
- Prick test Platanus acerifolia allergen extract
- Where
- 2 sites in Spain
- Volunteers
- 36 people
- Sponsor
- Laboratorios Leti, S.L.
Erythema, Telangiectasis
The Effect of 16-week Dietary Intake of Food Supplements Containing Collagen and MSM on Facial Erythema and Other Skin Parameters
The aim of this study is to compare the effects of 16 weeks of daily dietary supplementation with two investigational products containing collagen, methylsulfonylmethane (MSM), and vitamin C on skin parameters in comparison to a…
- Conditions
- Erythema, Telangiectasis, Skin Redness
- Trial name
- TO-COSKIN4 (NCT07345195)
- Testing
- CPMSM-HD, CPMSM-LD
- Where
- Slovenia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- VIST - Faculty of Applied Sciences
Systemic Lupus Erythematosus
Evaluation of Belimumab Impact on a BLyS Activity Signature Test in the Absence of Confounding Polypharmacy
This will be an open label, non-randomized trial of belimumab in at least 20 subjects to test the feasibility of belimumab as a single agent and to capitalize on simplified background treatment regimens to determine immunologic…
- Trial name
- BLAST (NCT02270970)
- Testing
- belimumab
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Oklahoma Medical Research Foundation
Juvenile Idiopathic Arthritis
Sleep Innovations for Preschoolers With Arthritis (SIPA): Developing and Pilot Testing of a Self-Management Intervention
Behavioral sleep problems such as sleep onset delays and frequent night wakings are common among young children (2-5 years). Children with a chronic health condition such as juvenile idiopathic arthritis (JIA) are even more prone…
- Trial name
- NCT04354337
- Testing
- Sleep Innovations for Preschoolers with Arthritis (SIPA)
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Washington
Metastatic Cancer, Breast Cancer
Efficacy of Point Of Service Testing in MBC
This study will assess the efficacy of an innovative point of service cancer genetics counseling delivery model for metastatic breast cancer (MBC) patients whom have received a referral for hereditary cancer genetic counseling…
- Trial name
- EPOST MBC (NCT03983577)
- Testing
- Point of service delivery model
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Kansas Medical Center
Breast Carcinoma
Droplet-BC Screening Test for the Detection of Breast Cancer, the DROPLET-BC Study
This study investigates if a new type of test called Droplet-BC screening test can classify breast cancer patients from non-cancer volunteers by circulating small-noncoding RNA in the blood with a statistical validity.
- Trial name
- NCT04671498
- Testing
- Biospecimen Collection, Droplet-BC Test, Electronic Health Record Review
- Where
- 3 sites in United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Preferred Medicine, Inc
Allergy Skin, Allergic Skin Reaction
SPT for Sensitization of Collagen Dressing
The goal of this clinical trial is to determine the sensitization (contact allergy) potential of the test product ColActive Plus Collagen Matrix Dressing after a skin prick test on the skin of healthy human subjects.
- Trial name
- NCT06271993
- Testing
- ColActivePlus Collagen Matrix Dressing
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Covalon Technologies Inc.
Breast Cancer
Multifunctional Magnetic Resonance Imaging in Predicting Breast Lesions in Women Undergoing Mastectomy for Breast Cancer
RATIONALE: Diagnostic procedures, such as multifunctional magnetic resonance imaging, may help doctors learn the extent of disease and plan the best treatment.
- Trial name
- NCT00602316
- Testing
- gadolinium-chelate, conventional surgery, magnetic resonance imaging
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Allergic Contact Dermatitis
Immune Reactions in Contact Dermatitis Affected Skin
This study hopes to improve the investigators understanding of how the immune system acts in allergic contact dermatitis. In order to reach this goal, normal volunteers, who are suspected of having allergic contact dermatitis…
- Trial name
- NCT01546298
- Testing
- Patch tests
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Rockefeller University
Hereditary Angioedema
Social Evaluated Cold Pressor Test in Hereditary Angioedema Patients
This study aims to evaluate the differences in objective and subjective stress responses between patients with hereditary angioedema and healthy individuals to a stress-induced challenge like socially-evaluated cold pressure…
- Trial name
- FROSEN (NCT06414252)
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Rheumatoid Arthritis
Impact of Guided Care With the Vectra Multi-biomarker Disease Activity (MBDA) Blood Test
Nine months multi-center prospective, randomized observational study, two arm trial to evaluate the effect of MBDA score-guided care on disease activity and medical costs.
- Trial name
- CareFirst (NCT03810144)
- Testing
- Vectra MBDA Test
- Where
- 11 sites in United States
- Volunteers
- 444 people
- Sponsor
- Sequenom, Inc.
Extrahepatic Bile Duct Cancer, Gallbladder Cancer
Anonymous Testing of Pathology Specimens for BRCA Mutations in Ashkenazi Jewish Individuals Who Have Cancer
The intent of the proposed study is to describe the prevalence of the most common recurring mutations in BRCA1 and BRCA2, blmAsh , and the A636P MSH2 mutation among Ashkenazi Jewish individuals with a variety of cancer diagnoses.
- Conditions
- Extrahepatic Bile Duct Cancer, Gallbladder Cancer, Gastric Cancer, Lung Cancer
- Trial name
- NCT00588263
- Where
- United States
- Sponsor
- Memorial Sloan Kettering Cancer Center
Allergic Contact Dermatitis
Reliability of Expired Allergens in Patch Testing: A Comparative Study With Non-Expired Series
Patch testing remains the gold standard in the diagnosis of allergic contact dermatitis. Patches used in testing consist of a wide spectrum of allergens, with variability in the stability of products over time.
- Trial name
- NCT07765563
- Testing
- Patch 1 (Expired), Patch 2 (non-expired)
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of Calgary
Early Breast Cancer, Premenopausal Breast Cancer
Optimising Adjuvant Chemotherapy Prescription in Young Patients With Hormone-dependent Breast Cancer Using Genomic Tests
Rationale: Around 70 to 80% of breast cancers are so-called "hormone-dependent" (HR+)/HER2-. For more than 50 years, studies have shown that chemotherapy and optimised hormonal treatments (hormone therapy), including a drug…
- Conditions
- Early Breast Cancer, Premenopausal Breast Cancer, HR+/HER2- Breast Cancer
- Trial name
- OPTIMA-YOUNG (NCT07106632)
- Testing
- test-directed treatment: allocated treatment will depend on the PAM50 score result (centrally assessed) : chemo-endocrine therapy or endocrine therapy alone, In the control arm, the treatment will be as standard of care : chemo-endocrine therapy
- Where
- 105 sites in Belgium, France and 5 more
- Volunteers
- 3,380 people
- Sponsor
- UNICANCER
Rhinitis, Allergic, Allergy
Effect of Vitamin C on Allergy Skin Test
This study will assess the effect of taking vitamin C on allergy skin test.
- Trial name
- NCT05810233
- Testing
- Ascorbic acid 1000mg
- Where
- Malaysia
- Volunteers
- 90 people
- Sponsor
- National University of Malaysia
Asthma, Atrial Fibrillation
The Living With a Long-Term Condition Study
Psychological distress (anxiety and depression) is common in and experienced differently by people living with long-term health conditions (LTCs).
- Conditions
- Asthma, Atrial Fibrillation, Cancer, Cerebrovascular Disorders
- Trial name
- LTC (NCT06072287)
- Testing
- Living with LTC Questionnaire
- Where
- United Kingdom
- Volunteers
- 600 people
- Sponsor
- King's College London
Peanut Allergy
Evaluation of Allergenicity of Hypoallergenic Peanut Product in Peanut Allergic Subjects
This is a proof of concept study to determine the safety and allergenicity of hypoallergenic peanut product extract as compared to standard peanut extract in an adult population with known peanut allergy.
- Trial name
- peanut (NCT01489514)
- Testing
- Epicutaneous skin prick testing
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
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